Standard name
Human Ortholog
Description Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal wormannin resistance; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0.11 0.06 – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 0.22 0.43 0.13 0.3 0.36 0.44 0.49 0.47 0.59 0.59 0.51 0.59 0.32 0.23 0.42 0.59 0.6 – 0 0 0 0 0 0
Endoplasmic Reticulum 0.24 0.31 0.42 0.6 0.55 0.5 0.44 0.36 0.21 0.27 0.29 0.26 0.36 0.33 0.32 0.07 0 – 0.38 0.44 0.67 0.23 0.27 0.3
Endosome 0.06 0 0.12 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.09 – 0.05 0.05 0.05 0.05 0.05 0.07
Golgi 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0.07 0.16 0.2 0.24 0.17 0 0 0 0.09 0.07 – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0.59 0.29 0.42 0.07 0.14 0.08 0.09 0.14 0.08 0.08 0 0.06 0.41 0.47 0.34 0.16 0.16 – 0.5 0.42 0.21 0.66 0.61 0.54
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 3 3 9 11 12 8 27 10 8 8 5 0 0 1 5 4 – 0 0 0 0 1 0
Bud 0 1 1 3 1 3 4 7 6 9 4 6 0 0 0 0 2 – 2 1 1 0 0 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 2 4 2 5 4 9 13 0 0 0 1 3 – 0 0 0 0 0 0
Cytoplasm 79 56 26 67 108 146 216 244 182 221 149 238 7 10 16 26 41 – 5 6 2 1 0 2
Endoplasmic Reticulum 84 40 84 132 166 164 193 188 66 101 84 105 8 14 12 3 2 – 156 72 169 28 34 49
Endosome 22 2 24 7 8 9 16 16 13 9 4 5 0 1 0 5 6 – 19 9 12 6 6 10
Golgi 0 0 5 11 11 0 3 5 1 4 0 1 0 0 0 1 0 – 6 1 4 1 1 2
Mitochondria 0 0 3 3 2 14 18 38 50 75 70 69 0 0 0 4 5 – 2 0 2 0 0 1
Nucleus 1 0 0 1 1 0 0 2 0 1 2 0 0 0 1 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 1 0 1 0 1 2 7 0 0 1 3 0 0 0 0 0 – 9 1 4 1 4 2
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 209 38 85 16 41 28 39 74 26 30 12 24 9 20 13 7 11 – 202 70 54 81 79 88
Unique Cell Count 353 130 202 221 300 331 442 521 311 372 290 405 22 43 38 44 68 407 166 254 124 131 163
Labelled Cell Count 399 141 231 250 349 379 503 610 359 462 343 469 24 45 43 52 75 407 166 254 124 131 163


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.6 9.8 10.8 12.4 14.1 10.1 9.9 9.2 8.6 8.0 7.9 7.8 11.0 10.4 10.4 8.7 9.3 – 11.4 11.1 11.2
Std Deviation (1e-4) 1.7 1.7 2.1 2.5 2.7 2.3 1.7 1.6 1.8 1.7 1.6 1.4 1.4 1.5 1.4 1.2 1.7 – 2.1 2.3 1.6
Intensity Change (Log2) – – – 0.2 0.39 -0.09 -0.12 -0.22 -0.32 -0.43 -0.45 -0.47 0.03 -0.05 -0.05 -0.31 -0.21 – 0.09 0.05 0.06

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.6 1.5 1.4 0 2.2 1.2 0 0 0 0 0 0 0 0 –
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Cytoplasm 4.3 5.7 7.5 8.8 8.5 10.3 10.8 8.8 10.7 0 1.7 4.4 6.8 7.8 –
Endoplasmic Reticulum 3.7 3.0 1.8 0.5 -1.4 -5.0 -3.5 -2.9 -3.9 -0.5 -1.1 -1.2 -4.4 -5.9 –
Endosome -3.4 -4.1 -4.3 -4.0 -4.6 -3.3 -4.7 -4.9 -5.8 0 0 0 -0.1 -0.7 –
Golgi 1.3 0.7 0 0 0 0 0 0 0 0 0 0 0 0 –
Mitochondria 0 0 1.7 1.7 3.0 5.3 6.2 7.0 5.6 0 0 0 0 0 –
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 –
Vacuole -8.4 -7.2 -9.2 -9.9 -8.1 -9.1 -9.7 -10.4 -10.9 -0.1 0.5 -0.9 -3.3 -3.9 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0319 0.0005 0.0019 0.0114 0.0106 0.0008 0.0723 0.0005 0.0068 0.0027 0.0004 0.0003 – – – – – –
Bud 0.0009 0.0004 0.0002 0.0006 0.0007 0.0005 0.0006 0.0006 0.0003 0.0017 0.0003 0.0002 – – – – – –
Bud Neck 0.001 0.0007 0.0005 0.0052 0.0005 0.0009 0.0009 0.0005 0.0005 0.002 0.0004 0.0009 – – – – – –
Bud Periphery 0.0015 0.001 0.0003 0.0006 0.0016 0.0008 0.0011 0.0018 0.0007 0.0023 0.0005 0.0005 – – – – – –
Bud Site 0.0042 0.0024 0.0021 0.0285 0.0005 0.0005 0.0028 0.0011 0.0006 0.0018 0.0007 0.0005 – – – – – –
Cell Periphery 0.0015 0.0051 0.0016 0.0009 0.0014 0.0008 0.0024 0.0032 0.0027 0.0031 0.0011 0.002 – – – – – –
Cytoplasm 0.1169 0.1926 0.0965 0.1192 0.0265 0.0728 0.0306 0.1737 0.0894 0.1382 0.0681 0.0639 – – – – – –
Cytoplasmic Foci 0.0126 0.0185 0.0317 0.0293 0.0106 0.0089 0.0145 0.0104 0.0193 0.0217 0.0151 0.0127 – – – – – –
Eisosomes 0.0006 0 0.0001 0.0002 0.0001 0 0.0008 0 0.0001 0.0001 0 0 – – – – – –
Endoplasmic Reticulum 0.2603 0.3578 0.3309 0.1794 0.0881 0.3673 0.4746 0.384 0.4545 0.2462 0.176 0.44 – – – – – –
Endosome 0.1639 0.0771 0.2265 0.3317 0.1814 0.1708 0.1251 0.1142 0.112 0.2222 0.3269 0.1705 – – – – – –
Golgi 0.0358 0.0026 0.0181 0.0132 0.0062 0.0049 0.0158 0.0048 0.0055 0.0208 0.0187 0.0113 – – – – – –
Lipid Particles 0.0219 0.0456 0.0218 0.0163 0.0064 0.0145 0.0312 0.0245 0.038 0.0233 0.0086 0.012 – – – – – –
Mitochondria 0.014 0.0017 0.0035 0.0028 0.0074 0.003 0.0149 0.0034 0.0182 0.0271 0.0064 0.0036 – – – – – –
None 0.0342 0.0056 0.0103 0.0026 0.0011 0.0125 0.0039 0.0047 0.0052 0.0044 0.0018 0.0008 – – – – – –
Nuclear Periphery 0.099 0.0627 0.0457 0.0633 0.1153 0.0852 0.0477 0.0416 0.0623 0.0344 0.0359 0.0525 – – – – – –
Nucleolus 0.0009 0.0003 0.0007 0.0004 0.0004 0.0003 0.0003 0.0003 0.0006 0.0058 0.0002 0.0003 – – – – – –
Nucleus 0.0136 0.025 0.0083 0.0054 0.0085 0.0092 0.0024 0.0047 0.0047 0.0074 0.0022 0.0036 – – – – – –
Peroxisomes 0.0011 0.0002 0.0089 0.0041 0.0002 0.0027 0.0079 0.0003 0.008 0.0036 0.0004 0.0003 – – – – – –
Punctate Nuclear 0.0023 0.0013 0.0033 0.001 0.0012 0.0006 0.0023 0.0008 0.0013 0.0086 0.0003 0.0003 – – – – – –
Vacuole 0.1603 0.1872 0.169 0.1505 0.4542 0.2053 0.1355 0.2089 0.1544 0.1941 0.2856 0.2012 – – – – – –
Vacuole Periphery 0.0217 0.0116 0.0181 0.0334 0.0774 0.0377 0.0122 0.0161 0.0149 0.0284 0.0505 0.0226 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.9113 12.0483 15.7633 25.2369 21.8432 13.8248 22.0399 21.7452 21.6286 24.702
Translational Efficiency 0.739 1.1115 0.9147 0.6078 0.5805 1.0113 0.5887 0.613 0.642 0.5427

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2318 981 237 943 1634 421 226 1517 3952 1402 463 2460

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 926.10 1009.07 1029.85 1115.01 1199.22 986.89 1145.24 1038.77 1039.02 1002.41 1086.17 1068.00
Standard Deviation 111.06 167.23 124.92 164.80 219.24 178.56 126.24 155.30 212.60 171.01 138.18 163.27
Intensity Change Log 2 — 0.123786 0.153194 0.267817 — -0.281135 -0.066446 -0.207220 — -0.090597 0.033395 0.019191

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000241 0.000371 0.000580 0.001447 0.003198 0.000238 0.000161 0.000487 0.001463 0.000331 0.000376 0.000855
Bud Neck 0.003907 0.000769 0.005758 0.007581 0.000258 0.001176 0.002358 0.004006 0.002398 0.000891 0.004099 0.005376
Bud Site 0.004564 0.004998 0.008534 0.028241 0.005511 0.005526 0.002677 0.013733 0.004955 0.005157 0.005675 0.019294
Cell Periphery 0.000173 0.000834 0.000204 0.000839 0.006990 0.000555 0.000247 0.000430 0.002991 0.000750 0.000225 0.000587
Cytoplasm 0.052098 0.040852 0.069575 0.077267 0.009641 0.033419 0.038126 0.070692 0.034544 0.038620 0.054224 0.073213
Cytoplasmic Foci 0.034299 0.046295 0.041605 0.042465 0.005220 0.047502 0.011172 0.057456 0.022276 0.046657 0.026750 0.051709
Eisosomes 0.000047 0.000048 0.000025 0.000065 0.000491 0.000044 0.000016 0.000035 0.000231 0.000047 0.000021 0.000046
Endoplasmic Reticulum 0.216004 0.650395 0.078048 0.118197 0.938651 0.453662 0.425380 0.195252 0.514791 0.591319 0.247588 0.165714
Endosome 0.075558 0.052793 0.070368 0.082343 0.004712 0.063815 0.051968 0.106080 0.046266 0.056103 0.061386 0.096981
Golgi 0.004109 0.012723 0.005175 0.010164 0.003319 0.008651 0.002839 0.010317 0.003782 0.011500 0.004035 0.010258
Lipid Particles 0.028751 0.014605 0.016376 0.028162 0.007127 0.018588 0.011421 0.028140 0.019810 0.015801 0.013957 0.028148
Mitochondria 0.004655 0.002366 0.000858 0.001163 0.001854 0.006092 0.000230 0.001870 0.003497 0.003485 0.000551 0.001599
Mitotic Spindle 0.003320 0.000303 0.017372 0.006778 0.000077 0.001910 0.001621 0.003688 0.001979 0.000785 0.009684 0.004872
None 0.000174 0.001994 0.000317 0.000922 0.002732 0.000803 0.000061 0.000299 0.001232 0.001636 0.000192 0.000538
Nuclear Periphery 0.021310 0.001577 0.024701 0.003794 0.000174 0.005186 0.019952 0.004572 0.012571 0.002661 0.022383 0.004274
Nuclear Periphery Foci 0.015725 0.012239 0.157167 0.029875 0.000932 0.014633 0.105078 0.029681 0.009608 0.012958 0.131742 0.029755
Nucleolus 0.001434 0.000667 0.003812 0.000477 0.000261 0.000763 0.000243 0.000360 0.000949 0.000696 0.002070 0.000405
Nucleus 0.017339 0.003425 0.019242 0.006206 0.002030 0.003271 0.005752 0.004598 0.011010 0.003379 0.012657 0.005214
Peroxisomes 0.000998 0.001004 0.000765 0.000936 0.004236 0.001023 0.000118 0.000600 0.002337 0.001010 0.000449 0.000729
Vacuole 0.496161 0.116661 0.376868 0.536154 0.001957 0.262881 0.307995 0.439847 0.291827 0.160569 0.343250 0.476764
Vacuole Periphery 0.019134 0.035081 0.102648 0.016925 0.000629 0.070260 0.012584 0.027858 0.011483 0.045645 0.058686 0.023667

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.48 -3.60 -4.14 -3.67 -2.80 4.64 4.76 4.17 -2.57 -3.45 4.21 3.99 2.09 -4.04 -3.59
Bud Neck 12.20 -3.12 -6.96 -12.91 -2.71 -5.02 -7.27 -16.74 -10.48 -4.58 9.08 -4.82 -11.04 -17.50 -3.35
Bud Site -0.50 -3.14 -7.88 -7.70 -5.92 0.00 2.50 -5.54 -4.57 -8.53 -0.22 -1.14 -9.99 -9.60 -8.81
Cell Periphery -9.11 -1.59 -3.57 0.44 -3.33 7.72 8.09 7.87 1.71 -2.33 6.36 7.92 6.86 2.24 -4.17
Cytoplasm 3.53 -2.06 -6.33 -8.23 -1.55 -5.82 -4.65 -17.17 -7.77 -4.74 -1.06 -3.71 -13.68 -10.91 -3.80
Cytoplasmic Foci -3.49 -1.81 -2.53 1.40 0.10 -9.06 -3.38 -21.82 -1.82 -16.14 -8.95 -1.94 -15.37 -1.35 -8.96
Eisosomes -0.10 5.52 -2.46 -1.75 -6.10 5.77 6.14 5.90 1.62 -6.16 5.66 6.50 5.75 0.28 -8.08
Endoplasmic Reticulum -36.66 13.47 12.72 44.16 -2.64 26.81 22.99 94.56 14.14 9.89 -6.74 17.24 42.71 41.10 5.86
Endosome 6.90 1.06 0.01 -5.59 -0.95 -13.29 -10.70 -33.97 -7.36 -9.68 -4.02 -4.43 -18.27 -11.76 -8.15
Golgi -6.87 -1.11 -3.21 2.26 -2.39 -4.03 0.33 -6.67 -0.81 -3.90 -8.10 -0.20 -6.83 1.77 -4.80
Lipid Particles 7.83 4.84 -0.17 -6.42 -4.38 -4.10 -2.44 -11.96 -3.09 -7.18 2.74 3.50 -5.95 -7.48 -7.83
Mitochondria 2.84 5.29 4.92 3.09 -0.78 -1.94 3.71 0.12 1.99 -5.97 -0.02 6.45 4.08 2.76 -4.93
Mitotic Spindle 3.72 -3.46 -2.89 -5.04 2.07 -1.04 -1.55 -4.74 -1.58 -2.36 1.73 -3.54 -4.34 -5.42 1.47
None -2.07 -1.58 -0.96 1.10 -0.74 1.66 2.65 2.41 0.93 -2.41 -0.53 2.49 1.54 1.69 -1.14
Nuclear Periphery 14.10 -1.11 11.53 -4.29 7.54 -4.76 -6.36 -10.16 0.44 4.85 11.02 -4.42 9.02 -3.67 8.64
Nuclear Periphery Foci 2.20 -11.16 -6.32 -7.45 9.73 -4.32 -9.69 -14.59 -4.34 6.82 -2.19 -14.49 -12.92 -9.11 11.78
Nucleolus 1.92 -2.49 4.66 0.39 3.54 -1.26 0.07 -0.46 1.18 -1.13 0.87 -2.21 3.98 0.98 3.42
Nucleus 9.17 -0.60 8.12 -3.08 3.70 -1.22 -2.48 -3.32 -2.60 0.91 7.26 -1.05 6.50 -2.96 3.86
Peroxisomes 0.00 1.55 0.89 0.32 -0.64 4.78 6.46 5.69 1.98 -7.94 3.31 6.79 5.93 1.05 -2.72
Vacuole 45.23 7.15 -4.21 -39.10 -9.21 -20.19 -15.83 -59.21 -12.20 -6.38 16.69 -3.85 -23.90 -38.92 -9.98
Vacuole Periphery -6.54 -6.80 2.78 7.76 7.14 -12.04 -5.12 -20.70 7.41 -5.44 -13.87 -7.03 -10.05 9.19 5.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal wormannin resistance; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
Localization
Cell Percentages ER (68%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Vsb1

Vsb1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vsb1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available