ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.06
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 0.16 0.14 0.11 0.13 0.2 0.18 – 0.21 0.22 0.19 0.22 0.23 0.22 0.27 0.21 0.2 0.22 0.12 0.06 0.1 0.13 0.1 0.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.08 0 – 0.1 0.08 0.13 0.15 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.61 0.74 0.75 0.85 0.75 0.63 0.61 – 0.52 0.54 0.56 0.52 0.61 0.71 0.57 0.54 0.41 0.41 0.47 0.56 0.5 0.37 0.33 0.37
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.34 0.24 0.13 0.06 0.21 0.17 0.28 – 0.26 0.23 0.22 0.2 0.22 0.12 0.22 0.32 0.43 0.4 0.3 0.3 0.3 0.39 0.4 0.31
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 2 1 1 1 0 0 0 0 1 0 0 1 1 0 1 1
Bud 0 0 0 0 0 1 0 – 4 4 4 4 0 0 0 0 0 0 8 9 3 12 21 23
Bud Neck 0 0 0 0 0 1 0 – 0 1 0 0 0 0 0 0 0 0 1 2 3 5 17 17
Bud Site 0 0 0 0 0 2 0 – 0 1 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 2 1 – 1 1 2 1 5 4 10 0 0 3 0 0 0 0 0 0
Cytoplasm 22 41 21 31 48 61 76 – 83 94 67 75 67 77 109 51 22 28 30 17 17 28 53 39
Endoplasmic Reticulum 0 4 0 2 1 2 1 – 1 5 1 2 3 5 1 11 6 6 7 0 2 3 12 12
Endosome 5 0 1 1 1 0 0 – 2 4 3 1 1 0 1 7 3 4 2 3 1 1 4 4
Golgi 0 0 1 0 0 0 0 – 0 0 0 0 0 1 1 1 0 0 0 1 1 0 2 4
Mitochondria 2 5 2 0 0 25 5 – 38 33 46 51 1 0 0 3 0 2 1 0 2 1 4 3
Nucleus 129 189 112 231 284 194 265 – 206 229 200 175 182 244 231 130 45 53 122 165 87 84 175 141
Nuclear Periphery 3 0 0 0 0 0 0 – 0 0 0 0 0 1 0 1 0 0 2 0 0 0 5 3
Nucleolus 1 0 0 0 0 0 0 – 0 2 0 0 0 0 0 0 0 0 0 0 0 0 3 5
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 2 0 0 0 0 0 0 0 0 0 1 0 0 6 4
Vac/Vac Membrane 72 62 20 17 79 52 120 – 102 97 79 68 65 43 89 77 47 52 77 86 52 90 214 118
Unique Cell Count 210 255 149 272 377 310 431 395 426 359 335 296 344 406 242 110 129 261 294 177 231 533 383
Labelled Cell Count 234 301 157 282 413 340 468 439 474 404 379 324 375 442 281 124 148 261 294 177 231 533 383


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.2 6.9 7.1 7.3 8.3 6.1 7.9 – 7.4 7.3 7.3 7.3 8.3 7.5 8.7 11.1 12.3 12.3 7.2 7.3 7.7
Std Deviation (1e-4) 1.3 0.8 0.9 1.3 1.5 1.3 1.4 – 1.6 1.3 1.3 1.2 1.1 1.3 1.5 1.9 2.1 2.0 1.4 1.3 1.5
Intensity Change (Log2) – – – 0.04 0.22 -0.21 0.15 – 0.06 0.05 0.04 0.04 0.23 0.07 0.3 0.65 0.79 0.79 0.01 0.04 0.11

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.8 -0.4 1.5 1.0 – 1.8 2.1 1.2 2.1 2.1 2.1 3.1 1.7 1.3 1.7
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.9 0 – 3.3 2.8 4.0 4.5 0 0 0 0 0 0
Nucleus 2.5 0 -2.7 -3.0 – -4.9 -4.6 -4.1 -4.7 -2.9 -1.0 -3.9 -4.2 -5.6 -5.8
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole -2.5 2.0 0.9 3.5 – 3.1 2.4 2.2 1.8 2.2 -0.3 2.2 4.1 5.3 5.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6955 2.0536 1.9032 1.6659 0.7468 1.8534 3.3375 3.7226 3.4586 3.1898 2.7335 3.0915 5.3296 6.4496 5.325 5.738 5.4512 5.4875
Actin 0.0115 0.0003 0.0032 0.0002 0.0036 0.0019 0.0351 0.0011 0.0006 0.0132 0.0002 0.0029 0.0522 0.0005 0.014 0.0002 0.0038 0.0035
Bud 0.0003 0.0002 0.0001 0.0001 0.0005 0.0002 0.0006 0.0073 0.0026 0.0004 0.0003 0.0003 0.0009 0.0003 0.0007 0.0001 0.0002 0.0004
Bud Neck 0.005 0.0017 0.0011 0.0031 0.0037 0.0147 0.009 0.0028 0.0019 0.0058 0.0108 0.0158 0.0037 0.0012 0.0047 0.0009 0.0019 0.0202
Bud Periphery 0.0004 0.0001 0.0001 0 0.0008 0.0002 0.001 0.0014 0.0015 0.0003 0.0002 0.0003 0.0027 0.0002 0.0008 0 0.0002 0.0007
Bud Site 0.0016 0.003 0.0009 0.0003 0.0021 0.0004 0.0034 0.005 0.0078 0.0012 0.0017 0.0006 0.0027 0.0039 0.0047 0.0003 0.0009 0.001
Cell Periphery 0.0004 0.0003 0.0002 0.0001 0.0003 0.0002 0.0018 0.001 0.0005 0.0004 0.0005 0.0004 0.0011 0.0003 0.0004 0.0001 0.0001 0.001
Cytoplasm 0.2276 0.2362 0.1867 0.2141 0.0932 0.1618 0.3419 0.2887 0.2639 0.2175 0.405 0.2978 0.221 0.176 0.2132 0.207 0.1356 0.1744
Cytoplasmic Foci 0.0114 0.0014 0.0049 0.0004 0.0108 0.0023 0.0296 0.0024 0.0031 0.0012 0.0005 0.0014 0.0113 0.0007 0.0072 0.0007 0.0104 0.0019
Eisosomes 0.0002 0 0 0.0001 0.0001 0 0.0001 0 0 0.0002 0 0.0001 0.0003 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0157 0.0153 0.0143 0.0063 0.0076 0.0084 0.0273 0.0167 0.0064 0.004 0.0075 0.021 0.0122 0.0136 0.0074 0.0071 0.0095 0.0107
Endosome 0.0232 0.0031 0.0092 0.0008 0.0615 0.0032 0.0748 0.0027 0.0155 0.002 0.0008 0.004 0.0044 0.0014 0.0024 0.001 0.0174 0.0073
Golgi 0.0046 0.0001 0.003 0 0.015 0.0009 0.0153 0.0004 0.0041 0.0067 0 0.0056 0.0027 0.0001 0.0012 0 0.0093 0.0016
Lipid Particles 0.0162 0.0003 0.0081 0.0001 0.0311 0.0023 0.0182 0.0004 0.0005 0.0004 0.0001 0.0033 0.0041 0.0003 0.0005 0 0.0082 0.0008
Mitochondria 0.0048 0.0003 0.0016 0.0001 0.0097 0.0007 0.0029 0.0038 0.0038 0.0275 0.0002 0.0231 0.0134 0.0002 0.0013 0.0002 0.0122 0.0014
None 0.0188 0.0086 0.0078 0.0441 0.042 0.0076 0.0085 0.005 0.0039 0.0002 0.0004 0.0005 0.0191 0.0489 0.0168 0.0208 0.049 0.012
Nuclear Periphery 0.0418 0.0392 0.0392 0.0099 0.0446 0.018 0.0298 0.0263 0.0221 0.0137 0.0166 0.0163 0.0176 0.0208 0.0136 0.0145 0.012 0.0114
Nucleolus 0.0026 0.0021 0.0013 0.0006 0.003 0.002 0.0015 0.0035 0.0011 0.0008 0.0012 0.0018 0.001 0.0016 0.0011 0.0006 0.0016 0.0017
Nucleus 0.5698 0.6765 0.7062 0.716 0.6384 0.7582 0.3522 0.6091 0.6495 0.6997 0.5451 0.5966 0.603 0.7226 0.7007 0.742 0.6933 0.738
Peroxisomes 0.0196 0.0001 0.0018 0 0.0053 0.0021 0.011 0.0024 0.001 0.001 0 0.001 0.0152 0 0.0024 0 0.0256 0.0001
Punctate Nuclear 0.0159 0.0051 0.0064 0.0019 0.0128 0.0089 0.0075 0.0084 0.0022 0.0013 0.0029 0.0022 0.0028 0.0023 0.0037 0.0027 0.0051 0.0028
Vacuole 0.0072 0.0056 0.0032 0.0017 0.0113 0.0057 0.0266 0.0112 0.0072 0.0023 0.0056 0.0047 0.008 0.0049 0.0031 0.0016 0.003 0.0084
Vacuole Periphery 0.0014 0.0005 0.0006 0.0001 0.0027 0.0002 0.0017 0.0003 0.0008 0.0002 0.0002 0.0004 0.0005 0.0002 0.0002 0.0001 0.0006 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.7572 4.27 3.1685 7.8676 8.2575 1.5913 8.9946 7.2849 10.901 8.6343
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2313 1498 2604 2063 1596 2578 1218 1787 3909 4076 3822 3850

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 846.27 924.40 1133.47 1247.64 789.68 929.65 1137.10 1279.43 823.16 927.72 1134.63 1262.40
Standard Deviation 107.30 127.23 171.98 223.07 109.18 129.37 179.75 218.95 111.60 128.61 174.50 221.74
Intensity Change Log 2 — 0.127399 0.421556 0.560012 — 0.235420 0.526019 0.696161 — 0.180551 0.472926 0.627337

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000144 0.000560 0.000289 0.000871 0.000367 0.000290 0.001012 0.000980 0.000235 0.000389 0.000519 0.000921
Bud Neck 0.003537 0.006614 0.012243 0.032919 0.002216 0.010163 0.019519 0.027527 0.002998 0.008859 0.014562 0.030416
Bud Site 0.001071 0.003761 0.002432 0.014646 0.001540 0.004564 0.006724 0.010141 0.001263 0.004269 0.003800 0.012555
Cell Periphery 0.000487 0.000550 0.000318 0.000893 0.000401 0.000349 0.000892 0.000527 0.000452 0.000423 0.000501 0.000723
Cytoplasm 0.124755 0.139091 0.049613 0.063738 0.150193 0.139240 0.033420 0.072212 0.135141 0.139185 0.044453 0.067671
Cytoplasmic Foci 0.009805 0.008887 0.000174 0.001603 0.014907 0.006338 0.000733 0.001711 0.011888 0.007275 0.000352 0.001653
Eisosomes 0.000035 0.000042 0.000018 0.000064 0.000047 0.000023 0.000077 0.000047 0.000040 0.000030 0.000037 0.000056
Endoplasmic Reticulum 0.002898 0.013093 0.004112 0.014230 0.003530 0.003708 0.020369 0.011431 0.003156 0.007157 0.009293 0.012931
Endosome 0.000631 0.001413 0.000228 0.001657 0.001132 0.001504 0.001221 0.002530 0.000836 0.001471 0.000544 0.002062
Golgi 0.000318 0.000483 0.000026 0.000549 0.000493 0.000329 0.000165 0.000601 0.000389 0.000386 0.000070 0.000573
Lipid Particles 0.001343 0.001225 0.000105 0.000465 0.002757 0.001740 0.000426 0.000489 0.001920 0.001551 0.000207 0.000476
Mitochondria 0.001639 0.001229 0.000986 0.003188 0.001750 0.002441 0.001490 0.002776 0.001684 0.001996 0.001147 0.002996
Mitotic Spindle 0.001778 0.002060 0.000545 0.016528 0.001702 0.003550 0.000759 0.018820 0.001747 0.003002 0.000613 0.017592
None 0.002461 0.004145 0.003053 0.005886 0.006442 0.006289 0.002815 0.011010 0.004087 0.005501 0.002977 0.008264
Nuclear Periphery 0.001054 0.001636 0.001377 0.003263 0.001060 0.001604 0.001968 0.003028 0.001056 0.001616 0.001565 0.003154
Nuclear Periphery Foci 0.000502 0.001542 0.000188 0.000936 0.001061 0.000587 0.000622 0.001222 0.000730 0.000938 0.000326 0.001069
Nucleolus 0.001028 0.001324 0.000190 0.000732 0.001649 0.001492 0.000447 0.001069 0.001281 0.001430 0.000272 0.000888
Nucleus 0.840608 0.799917 0.919253 0.815086 0.799167 0.805252 0.889951 0.811831 0.823688 0.803291 0.909915 0.813576
Peroxisomes 0.000596 0.000653 0.000016 0.000121 0.001203 0.001220 0.000072 0.000145 0.000844 0.001011 0.000034 0.000132
Vacuole 0.005044 0.011542 0.004787 0.021414 0.008216 0.008683 0.017056 0.021268 0.006339 0.009734 0.008697 0.021346
Vacuole Periphery 0.000268 0.000233 0.000048 0.001210 0.000167 0.000636 0.000264 0.000636 0.000227 0.000488 0.000117 0.000944

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.68 -3.25 -11.90 -5.11 -15.05 0.30 -5.01 -4.31 -8.22 1.88 -1.52 -5.06 -9.93 -9.68 -10.71
Bud Neck -4.68 -13.63 -24.07 -21.54 -15.74 -7.37 -16.61 -24.10 -14.63 -4.64 -7.95 -21.33 -33.37 -24.06 -16.29
Bud Site -5.64 -5.66 -12.12 -8.43 -9.83 -4.23 -9.64 -10.83 -5.43 -1.31 -6.46 -10.47 -16.16 -9.47 -9.88
Cell Periphery -0.54 1.41 -2.14 -3.65 -7.13 1.08 -6.08 -1.33 -3.56 6.04 0.39 -0.51 -2.21 -6.26 -2.67
Cytoplasm -2.36 21.29 18.89 17.06 -2.01 1.69 22.65 17.42 18.46 -8.24 -0.92 30.32 25.60 25.29 -5.83
Cytoplasmic Foci 0.90 12.58 10.98 7.92 -3.12 6.37 11.85 11.66 8.08 -0.59 5.47 17.31 16.01 11.25 -3.06
Eisosomes -2.52 5.87 -12.38 -9.58 -18.70 7.52 -8.89 -3.60 -15.98 7.04 4.64 -2.21 -12.04 -18.52 -10.30
Endoplasmic Reticulum -12.12 -7.14 -18.24 -0.14 -14.36 -0.58 -20.75 -13.29 -12.02 11.43 -9.86 -19.53 -22.54 -9.54 -3.25
Endosome -4.20 4.12 -3.04 1.28 -6.08 -1.24 -0.23 -0.54 0.59 -0.24 -3.58 2.51 -2.44 1.25 -4.28
Golgi -0.67 2.03 0.36 1.10 -2.59 0.95 2.02 1.25 0.45 -0.97 0.12 2.99 1.05 1.08 -2.78
Lipid Particles 0.62 6.60 3.07 3.43 -10.57 1.51 3.59 3.41 2.84 -1.80 1.14 6.09 4.40 3.44 -11.24
Mitochondria 0.86 1.17 -2.96 -4.83 -8.28 -1.03 0.07 -2.07 -0.90 -7.58 -0.70 1.07 -3.62 -2.87 -11.71
Mitotic Spindle -0.22 1.45 -5.86 -5.58 -6.60 -1.97 0.07 -6.35 -5.24 -6.57 -1.89 1.25 -8.62 -7.38 -9.43
None -2.28 -1.10 -7.11 -2.13 -7.89 0.20 4.29 -1.32 -1.67 -6.11 -2.27 3.34 -4.72 -2.00 -9.15
Nuclear Periphery -6.26 -8.73 -17.50 -12.10 -13.27 -3.07 -10.49 -17.52 -9.17 -8.89 -4.99 -12.93 -24.73 -13.65 -16.83
Nuclear Periphery Foci -4.33 3.14 -1.79 2.60 -3.65 2.09 1.64 1.27 -1.45 -0.66 -0.62 3.08 -0.09 0.60 -3.85
Nucleolus -0.53 3.02 0.01 0.60 -5.12 0.28 3.60 0.97 0.74 -3.48 -0.51 4.72 0.58 1.12 -6.23
Nucleus 5.67 -15.65 5.45 -0.86 20.96 -0.86 -10.17 -2.21 -1.51 9.35 3.83 -19.13 2.57 -1.49 23.37
Peroxisomes -0.16 3.83 3.32 3.86 -5.46 -0.02 3.54 3.49 5.11 -0.82 -0.72 5.13 4.76 6.14 -5.22
Vacuole -6.95 -3.04 -16.11 -12.16 -15.03 0.20 -7.89 -12.17 -12.48 -4.61 -4.41 -7.35 -20.35 -17.66 -15.78
Vacuole Periphery 0.28 1.75 -0.78 -0.96 -1.60 -1.98 -0.47 -1.32 1.46 -0.42 -1.54 1.49 -1.00 0.38 -1.84
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS
Localization
Cell Percentages nucleus (52%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

YGR126W

YGR126W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ygr126w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available