Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the small subunit; null mutant does not grow on glycerol, is sensitive to 2,4-dichlorophenol, and accumulates large lipid droplets
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.07 0.05 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.15 0.13 0.07 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.05 0 0.16 0.05 0 0 0 0 0 0 0 0.07 0.12 0.05 0.07 0.06 0 0.08 0 0.05 0.05 0.06
Golgi 0 0 0.1 0.11 0 0 0 0 0 0 0 0 0.19 0.24 0.23 0.41 0.38 0.13 0 0.06 0 0 0.05 0
Mitochondria 0.96 0.91 0.73 0.91 0.8 0.85 0.9 0.82 0.95 0.9 0.95 0.9 0.83 0.66 0.67 0.05 0.09 0.1 0.83 0.69 0.82 0.77 0.69 0.65
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.08 0 0 0 0 0.06 0.08 0.08 0.1 0.05 0.07 0.08 0.08 0.05 0.06 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0.06 0.07 0.06 0.06 0.09 0.05 0 0 0 0 0.05 0.06 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0.07 0.12 0.12 0.36 0 0 0 0.07 0.1 0.08
SpindlePole 0 0 0.05 0 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0.09 0.08 0 0 0 0 0 0
Vac/Vac Membrane 0.09 0.16 0.12 0 0.15 0.11 0.08 0.06 0 0.08 0.05 0.07 0.17 0.24 0.17 0.14 0.09 0.2 0 0.05 0 0 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 8 0 0 0 0 3 1 0 2 2 2 1 0 2 4 2 1 1 2 1 4 9
Bud 6 1 3 5 5 8 10 9 12 8 8 4 0 1 2 5 6 4 0 1 0 0 1 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 5
Bud Site 2 0 0 0 0 0 4 3 5 4 4 3 0 0 0 4 2 1 – – – – – –
Cell Periphery 3 2 2 7 4 6 6 2 5 2 3 3 4 4 6 9 12 6 0 0 0 0 0 0
Cytoplasm 3 2 4 4 7 9 8 11 4 9 8 6 4 5 3 2 2 2 0 0 1 0 0 0
Endoplasmic Reticulum 3 2 1 0 0 3 0 2 2 2 0 1 4 5 11 1 2 0 1 0 0 0 0 0
Endosome 3 0 5 4 48 19 14 10 5 3 0 6 9 17 30 3 6 5 13 11 3 7 14 24
Golgi 0 1 10 20 13 3 0 2 1 2 0 2 39 58 56 24 35 11 3 8 2 6 16 15
Mitochondria 282 122 71 169 246 302 405 312 400 456 329 335 172 156 165 3 8 8 242 104 91 114 212 250
Nucleus 2 4 1 0 1 7 7 13 6 10 0 2 1 0 2 1 1 1 0 2 0 0 2 1
Nuclear Periphery 23 1 0 4 9 22 35 32 44 27 24 31 16 11 14 0 1 1 7 5 0 1 3 7
Nucleolus 16 2 2 2 5 10 26 27 25 30 30 20 4 6 6 1 5 5 1 0 0 0 5 3
Peroxisomes 4 0 2 6 20 6 3 4 4 5 0 2 2 6 17 7 11 30 12 2 1 10 30 29
SpindlePole 4 0 5 3 16 11 10 11 7 15 3 8 5 3 6 3 8 7 2 1 0 0 2 6
Vac/Vac Membrane 26 22 12 8 46 40 36 21 16 40 18 26 34 57 41 8 8 17 2 7 4 3 10 22
Unique Cell Count 295 134 97 185 309 357 452 379 422 504 348 372 206 238 248 59 91 83 292 151 111 150 308 384
Labelled Cell Count 377 161 126 232 420 446 564 462 537 613 429 451 296 330 359 73 111 100 292 151 111 150 308 384


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 7.0 6.7 6.9 6.7 5.8 5.4 6.2 5.4 5.8 5.2 5.9 7.7 7.7 7.3 8.0 9.2 8.7 6.8 7.6 7.6
Std Deviation (1e-4) 0.7 1.2 2.2 1.8 1.4 1.3 1.2 1.3 1.1 1.2 1.2 1.3 1.2 1.2 1.1 1.5 1.8 1.9 1.4 1.7 1.7
Intensity Change (Log2) – – – 0.03 -0.01 -0.21 -0.32 -0.13 -0.31 -0.23 -0.38 -0.18 0.19 0.19 0.12 0.24 0.45 0.36 0.01 0.18 0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 -1.1 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 2.9 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 2.6 0.1 0 0 0 0 0 0 0 0.7 1.9 0 0.4 0
Golgi 0.1 -2.3 0 0 0 0 0 0 0 1.9 2.9 2.6 4.5 4.5 0.6
Mitochondria 4.1 1.3 2.6 4.3 2.0 6.6 4.7 6.2 4.3 2.1 -1.4 -1.2 -8.3 -8.9 -8.6
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 2.8 3.0 3.3 0 2.7 2.9 2.8 0 0 0 0 0
Nucleolus 0 0 0 0 1.9 1.5 1.6 2.2 0 0 0 0 0 0 0
Peroxisomes 0 1.7 0 0 0 0 0 0 0 0 0 1.8 0 2.7 6.0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 1.0 0.9
Vacuole -2.5 0.6 -0.3 -1.4 -2.4 -3.4 -1.4 -2.5 -1.7 0.9 2.4 1.0 0.2 -0.8 1.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.5292 6.8648 6.7595 6.7648 5.7748 7.0333 6.8033 7.1929 7.0693 6.1383 5.705 6.6073 6.213 5.8929 5.651 5.3945 5.7693 5.7517
Actin 0.0093 0.0098 0.0097 0.0383 0.0015 0.0011 0.0112 0.003 0.0059 0.0459 0.0236 0.0007 0.0286 0.0118 0.0107 0.0015 0.023 0.0019
Bud 0.0003 0.0005 0.0002 0.0004 0.0001 0 0.0004 0.0002 0.0001 0.0002 0.0013 0 0.0005 0.0013 0.0001 0.0001 0.0006 0
Bud Neck 0.0043 0.0004 0.0001 0.0026 0 0.0001 0.0008 0.0001 0.0002 0.0011 0.0005 0 0.0008 0.0002 0.0001 0.0004 0.0004 0.0001
Bud Periphery 0.0005 0.001 0.0003 0.0008 0.0002 0.0001 0.0008 0.0004 0.0003 0.0004 0.003 0.0001 0.0008 0.0015 0.0002 0.0003 0.0013 0.0001
Bud Site 0.0038 0.0013 0.0012 0.0028 0.0001 0.0001 0.0015 0.0004 0.0004 0.0011 0.0053 0 0.0036 0.0014 0.0003 0.0012 0.0028 0
Cell Periphery 0.0003 0.0002 0.0001 0.0003 0 0.0001 0.0002 0.0001 0.0001 0.0002 0.0002 0.0001 0.0004 0.0002 0.0001 0.0003 0.0002 0
Cytoplasm 0.0033 0.0001 0.0001 0.0002 0.0001 0.0001 0.0015 0.0001 0.0009 0.0001 0.0006 0 0.001 0.004 0.0002 0.0012 0.0001 0.0078
Cytoplasmic Foci 0.0144 0.0034 0.009 0.0218 0.002 0.0033 0.0186 0.0026 0.0021 0.0024 0.005 0.0004 0.0097 0.0114 0.0024 0.0016 0.0022 0.0008
Eisosomes 0.0003 0.0002 0.0002 0.0004 0.0002 0.0001 0.0005 0.0001 0.0002 0.0005 0.0004 0.0001 0.0007 0.0006 0.0004 0.0001 0.0004 0.0001
Endoplasmic Reticulum 0.0018 0.0001 0.0002 0.0002 0.0003 0.0003 0.0052 0.0003 0.0007 0.0004 0.0012 0 0.0011 0.0002 0.0001 0.0086 0.0001 0.0008
Endosome 0.0295 0.0167 0.0058 0.0079 0.0055 0.0083 0.0228 0.0257 0.0108 0.0077 0.0271 0.0044 0.0196 0.0127 0.0037 0.0112 0.0092 0.0047
Golgi 0.0212 0.055 0.0168 0.0123 0.0101 0.017 0.0266 0.035 0.0196 0.0129 0.0117 0.018 0.0239 0.049 0.0148 0.0041 0.0155 0.0269
Lipid Particles 0.027 0.0025 0.0134 0.0125 0.0048 0.0037 0.0261 0.0059 0.0074 0.0068 0.0188 0.0012 0.0399 0.0073 0.0068 0.0047 0.0043 0.0084
Mitochondria 0.8482 0.8862 0.9287 0.8892 0.9338 0.9508 0.8414 0.9083 0.921 0.9152 0.857 0.9715 0.8102 0.8695 0.9469 0.9417 0.9268 0.9424
None 0.0009 0 0.0001 0.0002 0.0002 0 0.005 0.0001 0.0018 0.0001 0.0025 0 0.0009 0.0001 0.0004 0.0003 0.0001 0
Nuclear Periphery 0.0049 0.0001 0.0002 0.0001 0.031 0.0011 0.0046 0.0003 0.0024 0.0002 0.009 0 0.0022 0.0001 0.0001 0.0077 0.0004 0.0001
Nucleolus 0.0017 0.0005 0.0001 0.0001 0.0002 0.0001 0.0006 0.0001 0.0004 0.0001 0.0013 0 0.007 0.0001 0.0001 0.0004 0.0011 0
Nucleus 0.0035 0.0003 0.0001 0.0001 0.0005 0.0002 0.0011 0.0001 0.0008 0.0001 0.0015 0 0.0012 0.0001 0.0001 0.0008 0.0009 0
Peroxisomes 0.0151 0.014 0.0117 0.0067 0.0045 0.0059 0.0163 0.0029 0.0056 0.0029 0.014 0.0013 0.0239 0.0216 0.0089 0.0072 0.0067 0.0027
Punctate Nuclear 0.0021 0 0.0002 0.0002 0.0031 0.0001 0.0087 0 0.0016 0.0002 0.0052 0 0.0012 0.0003 0.001 0.0001 0.0002 0
Vacuole 0.0044 0.0047 0.0005 0.0013 0.0004 0.0025 0.0016 0.0063 0.0052 0.0005 0.0061 0.0003 0.0097 0.0015 0.0007 0.0046 0.0015 0.0004
Vacuole Periphery 0.0034 0.003 0.001 0.0016 0.0014 0.0051 0.0046 0.008 0.0122 0.0011 0.0044 0.0017 0.013 0.0052 0.0022 0.002 0.0023 0.0025

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.9177 19.0053 21.8593 26.7883 33.0777 21.2484 28.8244 29.506 28.942 30.6876
Translational Efficiency 1.2255 1.7131 1.39 1.2228 0.9256 1.6775 1.2724 1.2245 1.3762 1.3985

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1847 311 2621 1633 1593 1669 962 1203 3440 1980 3583 2836

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 854.97 990.91 1159.99 1130.48 854.48 891.33 1199.65 1183.92 854.74 906.97 1170.64 1153.15
Standard Deviation 116.66 157.95 243.31 203.93 129.61 137.31 206.38 172.07 122.83 145.34 234.63 192.88
Intensity Change Log 2 — 0.212880 0.440167 0.402990 — 0.060913 0.489495 0.470453 — 0.138918 0.465035 0.437106

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000720 0.004459 0.005153 0.008940 0.001249 0.003521 0.003378 0.008577 0.000965 0.003668 0.004677 0.008786
Bud Neck 0.001341 0.002250 0.001247 0.000951 0.000620 0.002265 0.007319 0.002379 0.001007 0.002263 0.002877 0.001557
Bud Site 0.003976 0.006369 0.003895 0.003447 0.001789 0.004423 0.014737 0.012751 0.002963 0.004729 0.006806 0.007394
Cell Periphery 0.000254 0.000764 0.001026 0.000815 0.000254 0.000245 0.000549 0.000676 0.000254 0.000327 0.000897 0.000756
Cytoplasm 0.001003 0.001016 0.000502 0.001088 0.000492 0.001865 0.003545 0.002333 0.000766 0.001732 0.001319 0.001616
Cytoplasmic Foci 0.012637 0.042978 0.006031 0.005447 0.017698 0.028366 0.023353 0.015051 0.014981 0.030661 0.010682 0.009521
Eisosomes 0.000035 0.000116 0.000133 0.000184 0.000039 0.000070 0.000136 0.000156 0.000037 0.000077 0.000134 0.000172
Endoplasmic Reticulum 0.000248 0.000383 0.000207 0.000501 0.000223 0.000381 0.000355 0.000444 0.000236 0.000381 0.000247 0.000477
Endosome 0.038325 0.056143 0.007177 0.007318 0.032571 0.050004 0.035887 0.018488 0.035660 0.050968 0.014885 0.012056
Golgi 0.023945 0.053845 0.015776 0.021528 0.020592 0.045848 0.027624 0.046784 0.022393 0.047104 0.018957 0.032242
Lipid Particles 0.004976 0.006204 0.001395 0.001770 0.006400 0.006314 0.006780 0.000677 0.005635 0.006296 0.002841 0.001306
Mitochondria 0.873910 0.738894 0.936977 0.922714 0.882602 0.807825 0.808608 0.836712 0.877935 0.796998 0.902511 0.886233
Mitotic Spindle 0.002796 0.011396 0.001952 0.002659 0.002589 0.004539 0.010819 0.010819 0.002700 0.005616 0.004333 0.006120
None 0.000165 0.000277 0.000644 0.000557 0.000165 0.000220 0.001237 0.000530 0.000165 0.000229 0.000803 0.000546
Nuclear Periphery 0.000315 0.000167 0.000235 0.000108 0.000170 0.000122 0.001115 0.000479 0.000248 0.000129 0.000471 0.000265
Nuclear Periphery Foci 0.000411 0.000264 0.000161 0.000116 0.000187 0.000390 0.000972 0.000358 0.000307 0.000370 0.000378 0.000219
Nucleolus 0.000122 0.000362 0.000169 0.000057 0.000043 0.000396 0.000702 0.000273 0.000085 0.000390 0.000312 0.000149
Nucleus 0.000204 0.000182 0.000139 0.000041 0.000036 0.000561 0.001188 0.000610 0.000126 0.000502 0.000421 0.000283
Peroxisomes 0.017302 0.054417 0.005661 0.011832 0.022714 0.030733 0.019789 0.016583 0.019808 0.034453 0.009454 0.013848
Vacuole 0.006903 0.011575 0.005089 0.003436 0.003587 0.006003 0.018700 0.012605 0.005367 0.006879 0.008744 0.007325
Vacuole Periphery 0.010414 0.007937 0.006429 0.006490 0.005979 0.005909 0.013208 0.012712 0.008360 0.006228 0.008250 0.009129

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.69 -6.20 -6.30 -2.38 -2.58 -3.27 -2.38 -4.77 -3.04 -2.96 -4.42 -6.44 -7.86 -4.44 -3.62
Bud Neck -1.73 0.27 1.26 2.84 1.52 -2.56 -5.54 -3.45 -0.28 3.65 -2.23 -4.92 -2.09 1.11 3.03
Bud Site -1.29 0.07 0.54 1.59 0.51 -2.98 -5.38 -5.39 -4.11 0.55 -2.30 -4.24 -4.38 -2.53 -0.58
Cell Periphery -1.00 -2.16 -3.88 -0.10 0.55 0.10 -2.28 -2.09 -2.32 -0.59 -0.79 -2.43 -4.17 -3.08 0.49
Cytoplasm -0.14 1.60 -0.22 -0.13 -1.93 -2.71 -3.07 -3.11 -0.71 0.97 -2.21 -1.70 -2.59 0.18 -0.80
Cytoplasmic Foci -5.43 5.53 6.02 6.76 0.65 -4.80 -2.22 1.29 5.98 3.23 -8.34 3.74 4.87 11.60 1.14
Eisosomes -3.22 -7.92 -10.70 -2.33 -2.80 -7.26 -5.13 -2.18 -1.59 -0.34 -7.74 -9.35 -5.62 -3.86 -1.47
Endoplasmic Reticulum -1.34 0.92 -1.78 -0.74 -2.10 -1.25 -2.03 -2.78 -0.53 -1.23 -1.40 -0.31 -2.71 -0.79 -2.68
Endosome -2.74 12.78 12.41 7.98 -0.13 -5.02 -0.89 5.24 10.44 5.21 -5.23 10.94 12.96 15.26 2.29
Golgi -4.63 3.94 0.94 4.92 -2.41 -8.57 -2.56 -6.79 -0.20 -4.48 -9.46 2.16 -4.45 4.88 -5.94
Lipid Particles -0.62 3.60 2.91 2.30 -0.73 0.05 -0.28 5.37 4.99 6.23 -0.55 3.59 5.57 4.83 3.74
Mitochondria 6.85 -9.75 -6.69 -9.40 2.48 7.91 6.55 4.71 -2.58 -2.20 10.15 -4.44 -1.30 -10.90 2.89
Mitotic Spindle -3.23 1.59 0.19 3.26 -1.13 -2.77 -4.64 -5.09 -3.81 -0.10 -4.14 -2.76 -4.35 -0.63 -2.05
None -3.45 -4.29 -12.01 -5.84 0.75 -1.19 -2.90 -6.80 -4.52 1.88 -1.69 -4.96 -12.83 -6.57 1.94
Nuclear Periphery 0.87 0.45 1.23 1.91 2.24 1.49 -3.08 -1.54 -1.79 1.73 1.29 -1.74 -0.14 -1.57 1.64
Nuclear Periphery Foci 0.58 1.27 1.49 2.66 1.35 -1.32 -3.73 -1.95 0.05 2.57 -0.41 -0.60 0.68 1.08 2.05
Nucleolus -1.00 -0.80 1.33 1.12 2.68 -2.09 -3.87 -2.45 0.58 2.14 -2.11 -3.81 -1.38 1.67 2.32
Nucleus -0.42 0.47 1.73 1.23 1.34 -2.36 -2.46 -1.92 -0.33 0.83 -2.01 -2.05 -1.26 0.83 0.52
Peroxisomes -4.77 5.66 2.15 5.51 -3.43 -2.44 0.90 1.95 4.22 1.05 -5.24 6.26 3.01 7.48 -2.77
Vacuole -1.50 2.10 3.91 2.64 2.20 -3.17 -8.51 -5.65 -3.96 2.57 -1.81 -4.64 -2.37 -0.48 1.44
Vacuole Periphery 1.36 3.72 3.33 0.80 -0.06 0.07 -5.56 -5.07 -5.08 0.30 2.60 0.13 -0.89 -3.21 -1.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the small subunit; null mutant does not grow on glycerol, is sensitive to 2,4-dichlorophenol, and accumulates large lipid droplets
Localization
Cell Percentages mitochondrion (98%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Mrps35

Mrps35


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrps35-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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