Standard name
Human Ortholog
Description Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bacteria; binds AU-rich RNA
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 0.15 0.42 0.52 0.48 0.49 0.48 0.34 0.15 0.52 0.31 0.54 0.36 – 0.44 0.43 0.2 0.26 0.16 0.66 0.67 0.68 0.64 0.59 0.66
Cytoplasm 0.95 0.67 0.74 0.68 0.63 0.67 0.75 0.9 0.74 0.84 0.78 0.84 – 0.69 0.67 0.75 0.86 0.82 0.3 0.25 0.27 0.3 0.35 0.27
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0.28 0.2 0.16 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 2 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 14 20 101 124 145 272 117 37 327 158 343 171 – 17 18 13 17 8 124 178 522 82 127 207
Cytoplasm 87 32 146 174 185 379 257 216 472 434 494 395 – 27 28 48 57 42 56 67 203 38 74 85
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 18 13 8 0 1 1 0 0 1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 4 0 0 0 10 0 2 – 1 0 0 0 0 4 8 4 2 5 7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 6 0 2 1
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 1 0 0 0
Unique Cell Count 92 48 196 256 294 566 344 240 634 518 633 473 39 42 64 66 51 189 267 763 128 215 313
Labelled Cell Count 101 52 247 298 330 655 374 254 799 603 837 568 45 46 79 87 58 189 267 763 128 215 313


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 820.9 802.1 900.2 842.3 802.4 793.5 751.1 716.1 792.1 714.1 775.9 725.5 – 827.7 827.2 899.2 869.3 895.3 851.2 816.9 801.8
Std Deviation (1e-4) 146.5 148.3 156.3 146.1 170.4 165.8 168.1 166.4 160.8 175.8 152.0 176.5 – 218.5 151.2 128.7 118.3 126.4 153.0 183.7 173.3
Intensity Change (Log2) – – – -0.1 -0.17 -0.18 -0.26 -0.33 -0.18 -0.33 -0.21 -0.31 – -0.12 -0.12 -0.0 -0.05 -0.01 -0.08 -0.14 -0.17

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005001000WT3HU120HU16005001000WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305001000WT1AF100AF140AF18005001000
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Cell Periphery -0.7 -0.5 -0.8 -4.0 -8.1 0 -5.2 0.7 -3.7 – -0.9 -1.0 -4.4 -3.6 -4.6
Cytoplasm -1.5 -2.7 -2.0 0.1 4.3 0 2.8 1.0 2.7 – -0.7 -1.0 0.1 2.0 1.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0041 0.0004 0.0095 0 0.0001 0.0042 0.0009 0.0003 0.0008 0 0.0047 0.0007 0.0116 0 0.0004 0.0001 0.001 0.0126
Bud 0.004 0.0004 0.0007 0 0.0005 0.0008 0.0015 0.0006 0.0003 0.0001 0.0005 0.0004 0.0034 0.0001 0.0006 0.0001 0.0006 0.0034
Bud Neck 0.0004 0 0.0006 0 0.0001 0.0002 0.0001 0.0001 0.0001 0 0.0004 0.0002 0.0005 0 0.0001 0 0.0001 0.0004
Bud Periphery 0.0013 0.0001 0.0008 0 0.0001 0.0016 0.0008 0 0.0002 0 0.0005 0.0001 0.0017 0 0.0002 0 0.0013 0.0015
Bud Site 0.0022 0.0002 0.0013 0 0.0006 0.0007 0.0008 0 0.0006 0 0.0015 0.0002 0.0065 0 0.0003 0.0002 0 0.001
Cell Periphery 0.0015 0.0003 0.0012 0 0.002 0.0002 0.0019 0.0001 0.0024 0 0.0051 0.0005 0.0033 0 0.0024 0.0002 0.0002 0.0003
Cytoplasm 0.0173 0.2877 0.1257 0.0019 0.0009 0.0161 0.0065 0.4388 0.1301 0.0102 0.0854 0.0089 0.0176 0.1315 0.2354 0.003 0.0028 0.1414
Cytoplasmic Foci 0.0105 0.0002 0.0313 0 0.2935 0.016 0.0014 0.0002 0.0167 0 0.0029 0.022 0.0836 0 0.0059 0.0034 0.0001 0.0003
Eisosomes 0.0015 0.0001 0.0016 0 0.01 0.0004 0.0032 0 0.0032 0 0.0227 0.0004 0.0034 0 0.0007 0.0013 0 0.0001
Endoplasmic Reticulum 0.0021 0 0.0095 0 0 0.0018 0.0001 0 0 0 0.0004 0.0001 0.0023 0 0 0 0.0016 0.0002
Endosome 0.0486 0 0.0591 0 0 0.007 0.0001 0 0.0001 0 0.0003 0.0002 0.0025 0 0.0002 0 0.0033 0.0002
Golgi 0.004 0 0.0125 0 0.0001 0.0013 0.0001 0 0.0002 0 0.0006 0.0001 0.0014 0 0.0001 0 0.0001 0.0001
Lipid Particles 0.0086 0 0.0069 0 0.0099 0.0021 0.0008 0 0.0023 0 0.0039 0.0014 0.0089 0 0.001 0.0003 0 0.0001
Mitochondria 0.0465 0.0121 0.0517 0.0017 0.374 0.0227 0.0714 0.0066 0.0497 0.0031 0.0652 0.0101 0.032 0.0038 0.022 0.0067 0.0053 0.0087
None 0.0183 0.0018 0.0311 0 0.0547 0.0042 0.0047 0.0014 0.0121 0.0001 0.0133 0.0167 0.0177 0.0001 0.0022 0.0057 0.0003 0.0016
Nuclear Periphery 0.0533 0.0172 0.0859 0.0013 0.0001 0.0188 0.0138 0.0151 0.0055 0.0024 0.0218 0.0661 0.0776 0.006 0.0158 0.0027 0.6508 0.0161
Nucleolus 0.2956 0.023 0.2255 0.028 0.2241 0.0716 0.3702 0.0048 0.1777 0.0052 0.3418 0.1551 0.2581 0.0061 0.2999 0.381 0.0015 0.046
Nucleus 0.4253 0.6543 0.2863 0.9668 0.0053 0.8026 0.5026 0.5291 0.5815 0.9782 0.3643 0.6961 0.4022 0.8518 0.3933 0.5796 0.0784 0.7589
Peroxisomes 0.0017 0.0001 0.0015 0 0.0157 0.0008 0.0006 0 0.0007 0 0.0014 0.0002 0.0023 0 0.0004 0.0001 0 0.0003
Punctate Nuclear 0.0417 0.0006 0.0381 0 0.0013 0.0202 0.008 0.0008 0.0045 0 0.0509 0.008 0.0428 0.0001 0.0006 0.0148 0.0002 0.0048
Vacuole 0.0055 0.0004 0.0092 0 0.0031 0.0027 0.0029 0.0005 0.0027 0.0001 0.0024 0.0016 0.01 0.0001 0.0046 0.0002 0.0281 0.0007
Vacuole Periphery 0.006 0.0011 0.0101 0.0001 0.0039 0.0041 0.0076 0.0016 0.0087 0.0004 0.01 0.011 0.0106 0.0004 0.0139 0.0006 0.2243 0.0014

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17673.2478 18137.8682 19503.5782 16161.9002 18696.7683 18148.0748 19135.3418 18271.1041 21473.981 17382.6511
Translational Efficiency 0.8581 0.8727 0.8394 0.8638 0.8131 0.9127 1.0364 1.0042 0.915 1.1651

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1451 1607 3143 28 1072 798 900 1001 2523 2405 4043 1029

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 55686.58 55626.22 57945.52 46921.60 54060.95 53756.80 54764.69 43754.34 54995.86 55005.93 57237.45 43840.52
Standard Deviation 4674.99 5666.96 6888.88 21872.49 4539.32 7637.25 7689.92 9549.98 4687.23 6448.80 7197.73 10099.69
Intensity Change Log 2 — -0.001565 0.057367 -0.247077 — -0.008140 0.018659 -0.305161 — -0.004800 0.038430 -0.275397

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000024 0.000012 0.000026 0.001010 0.000011 0.000100 0.000060 0.000219 0.000018 0.000041 0.000033 0.000241
Bud Neck 0.000086 0.000073 0.000036 0.005294 0.000050 0.000186 0.000229 0.000999 0.000071 0.000110 0.000079 0.001116
Bud Site 0.000032 0.000068 0.000136 0.003862 0.000006 0.001252 0.000989 0.003861 0.000021 0.000461 0.000326 0.003861
Cell Periphery 0.240118 0.471491 0.622869 0.253186 0.358581 0.257772 0.351574 0.120898 0.290452 0.400578 0.562477 0.124497
Cytoplasm 0.052696 0.018809 0.011224 0.044178 0.013422 0.038937 0.051470 0.316287 0.036009 0.025488 0.020183 0.308882
Cytoplasmic Foci 0.000005 0.000001 0.000333 0.018168 0.000003 0.000029 0.000781 0.000144 0.000004 0.000010 0.000433 0.000634
Eisosomes 0.000034 0.000057 0.000025 0.000042 0.000047 0.000044 0.000064 0.000023 0.000039 0.000052 0.000034 0.000024
Endoplasmic Reticulum 0.000013 0.000007 0.000005 0.000012 0.000012 0.000083 0.000009 0.000094 0.000012 0.000033 0.000006 0.000092
Endosome 0.000001 0.000001 0.000089 0.005370 0.000001 0.000010 0.000053 0.000038 0.000001 0.000004 0.000081 0.000183
Golgi 0.000025 0.000004 0.000065 0.004244 0.000009 0.000073 0.000389 0.000250 0.000018 0.000027 0.000137 0.000358
Lipid Particles 0.000212 0.000029 0.000025 0.000143 0.000033 0.000280 0.000135 0.003749 0.000136 0.000112 0.000049 0.003651
Mitochondria 0.000002 0.000001 0.000097 0.000140 0.000002 0.000895 0.000059 0.000265 0.000002 0.000297 0.000089 0.000262
Mitotic Spindle 0.000004 0.000006 0.000006 0.000247 0.000006 0.000050 0.000219 0.000021 0.000005 0.000021 0.000054 0.000027
None 0.000001 0.000000 0.000076 0.000076 0.000000 0.000083 0.000062 0.001622 0.000001 0.000028 0.000073 0.001580
Nuclear Periphery 0.000134 0.000047 0.000023 0.000115 0.000081 0.000315 0.000069 0.000152 0.000111 0.000136 0.000033 0.000151
Nuclear Periphery Foci 0.000067 0.000024 0.000013 0.000268 0.000023 0.000194 0.000108 0.000790 0.000048 0.000080 0.000034 0.000776
Nucleolus 0.000006 0.000004 0.000004 0.000036 0.000004 0.000051 0.000006 0.000121 0.000005 0.000020 0.000004 0.000118
Nucleus 0.000365 0.000076 0.000250 0.018327 0.000108 0.000689 0.001049 0.003511 0.000256 0.000279 0.000428 0.003914
Peroxisomes 0.000002 0.000000 0.000002 0.111103 0.000000 0.000040 0.000002 0.000036 0.000001 0.000013 0.000002 0.003058
Vacuole 0.705790 0.509190 0.364652 0.534019 0.627424 0.698088 0.592477 0.545500 0.672493 0.571868 0.415367 0.545187
Vacuole Periphery 0.000386 0.000101 0.000043 0.000160 0.000177 0.000830 0.000196 0.001421 0.000297 0.000343 0.000077 0.001386

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.76 -0.32 -1.08 -1.09 -1.07 -2.05 -2.01 -3.79 -1.49 -2.41 -1.63 -1.28 -3.84 -3.26 -3.40
Bud Neck 0.81 2.87 -1.24 -1.25 -1.26 -1.54 -2.34 -9.33 -6.28 -6.56 -1.17 -0.42 -7.61 -7.20 -7.52
Bud Site -0.81 -1.29 -1.31 -1.30 -1.26 -1.38 -1.75 -4.52 -2.11 -2.44 -1.45 -2.16 -4.61 -3.84 -4.09
Cell Periphery -23.09 -45.55 -0.24 4.80 8.14 8.33 0.56 24.46 14.78 21.91 -13.38 -36.62 23.89 35.29 61.73
Cytoplasm 10.80 14.46 0.62 -1.78 -2.32 -6.11 -8.90 -35.53 -29.94 -28.61 4.41 7.80 -32.17 -33.41 -34.38
Cytoplasmic Foci 2.85 -1.26 -1.56 -1.56 -1.53 -1.61 -1.06 -3.48 -2.90 0.74 -1.25 -1.64 -2.25 -2.22 -0.70
Eisosomes -2.49 0.70 -0.47 0.90 -0.88 0.10 -1.45 2.72 1.86 3.09 -1.84 0.47 2.16 3.43 1.05
Endoplasmic Reticulum 0.73 1.23 -0.05 -0.58 -0.91 -2.27 0.05 -3.04 0.06 -3.08 -1.95 1.16 -3.05 -1.87 -3.26
Endosome 1.79 -1.00 -1.38 -1.38 -1.35 -1.68 -1.04 -6.21 -3.81 0.14 -1.56 -1.16 -1.79 -1.76 -0.87
Golgi 1.70 -0.59 -1.22 -1.23 -1.21 -1.42 -0.99 -3.43 -1.72 0.38 -0.69 -1.19 -2.93 -2.77 -1.42
Lipid Particles 7.82 7.43 1.29 -2.17 -2.19 -2.93 -2.89 -10.26 -9.38 -9.94 0.78 4.88 -9.97 -10.01 -10.20
Mitochondria 0.77 -1.48 -1.11 -1.11 -0.46 -1.16 -1.83 -1.98 0.75 -1.38 -1.15 -1.80 -2.02 -0.00 -1.30
Mitotic Spindle -5.91 -0.94 -1.79 -1.77 -1.77 -1.00 -1.33 -1.58 0.50 1.21 -1.07 -1.37 -2.06 -0.61 0.61
None 1.79 -1.26 -1.03 -1.03 -0.15 -1.54 -1.59 -1.71 -1.60 -1.61 -1.53 -1.60 -1.71 -1.68 -1.62
Nuclear Periphery 9.67 12.46 0.22 -1.53 -1.98 -1.89 1.21 -6.29 1.39 -7.21 -0.83 12.86 -3.83 -0.03 -11.77
Nuclear Periphery Foci 7.73 9.56 -1.08 -1.32 -1.37 -1.87 -1.77 -10.84 -4.53 -8.29 -1.22 1.23 -10.56 -8.89 -10.65
Nucleolus 2.13 0.90 -1.42 -1.49 -1.49 -1.18 -1.00 -4.22 -1.58 -4.12 -1.10 0.27 -4.22 -3.38 -4.23
Nucleus 4.80 0.56 -0.99 -1.00 -0.99 -2.02 -1.86 -5.38 -4.47 -3.74 -0.73 -1.29 -5.10 -5.01 -4.85
Peroxisomes 5.84 -0.28 -2.03 -2.03 -2.03 -1.05 -1.16 -6.64 0.11 -5.66 -0.99 -1.02 -1.95 -1.94 -1.95
Vacuole 20.01 41.49 2.78 -0.30 -2.58 -5.67 2.75 7.76 13.40 4.40 12.53 35.91 14.27 3.55 -12.63
Vacuole Periphery 1.35 1.61 1.06 -1.46 -2.80 -1.76 -0.21 -4.89 -0.82 -4.38 -0.42 1.72 -3.87 -3.44 -5.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bacteria; binds AU-rich RNA
Localization
Cell Percentages cytoplasm (47%), cell periphery (1%), mixed (49%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Tdh3

Tdh3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tdh3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available