Standard name
Human Ortholog
Description Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.13 0.15 0.06 0.09 0.07 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0 0 0.05 0.06 0.12 0.22 0.12 0.16 0.17 0.24 0.18 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.39 0.17 0.15 0.15 0.29 0.24 0.32 0.43 0.44 0.56 0.52 0.64 0.22 0.26 0.56 0.64 0.63 0.69 0 0.05 0 0.07 0.09 0.1
Nuclear Periphery 0.76 0.66 0.77 0.84 0.68 0.69 0.51 0.47 0.51 0.38 0.42 0.32 0.78 0.68 0.45 0.2 0.15 0.12 0.9 0.83 0.9 0.78 0.68 0.54
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.28 0.49 0.35 0.2 0.24 0.2 0.16 0.2 0.18 0.16 0.14 0.14 0.23 0.22 0.12 0.23 0.19 0.17 0 0.07 0 0.07 0.14 0.25
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 1 3 6 4 2 3 4 4 0 0 0 0 0 1 2 1 4 3 4 2
Bud Neck 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Bud Site 0 0 0 0 1 2 5 4 3 8 9 12 0 2 1 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1 7 13 10 25 13 29 28 13 21 4 16 18 71 64 13 25 14 0 2 1 2 5 5
Endoplasmic Reticulum 0 0 1 0 1 2 1 0 0 0 1 0 1 0 1 8 8 10 0 0 1 0 0 3
Endosome 0 0 1 0 1 3 3 2 1 0 0 0 1 0 0 1 3 0 0 1 2 2 4 7
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 1 1 2
Mitochondria 23 4 20 23 40 105 245 117 133 160 170 180 2 0 1 1 2 6 4 1 10 8 12 18
Nucleus 128 35 84 69 193 206 356 426 362 533 375 653 64 137 239 140 169 135 5 11 11 25 45 59
Nuclear Periphery 253 136 421 380 448 583 572 475 416 355 306 331 223 358 191 43 41 24 301 193 498 278 340 301
Nucleolus 3 1 6 10 13 18 35 34 20 22 28 31 2 4 4 4 13 6 3 1 3 4 12 15
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 0 2 1 0 0 1 0 0 0 0 0 0
SpindlePole 0 1 1 0 0 1 1 1 1 2 0 0 0 6 9 0 0 0 3 0 2 2 3 1
Vac/Vac Membrane 94 100 189 88 157 167 181 197 147 153 98 139 65 115 53 50 52 34 9 15 14 25 69 140
Unique Cell Count 331 206 546 450 659 844 1112 1001 819 946 722 1019 286 528 429 220 269 196 334 233 556 359 503 562
Labelled Cell Count 502 284 737 580 880 1103 1435 1290 1098 1257 995 1366 376 696 564 261 314 231 334 233 556 359 503 562


Nuclear Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 7.9 7.0 6.7 6.6 5.6 5.3 5.6 5.3 5.3 5.1 5.2 9.2 8.7 8.5 10.3 9.4 8.7 8.7 9.0 9.5
Std Deviation (1e-4) 1.1 2.1 1.3 1.5 1.7 1.4 1.3 1.4 1.3 1.2 1.2 1.2 2.0 2.1 2.0 2.5 2.5 2.6 1.6 1.6 1.5
Intensity Change (Log2) – – – -0.05 -0.08 -0.3 -0.38 -0.32 -0.39 -0.38 -0.46 -0.41 0.4 0.33 0.28 0.56 0.44 0.32 0.32 0.38 0.44

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.2 1.4 -1.1 0.3 0.5 -1.1 -0.2 -2.8 -1.1 2.8 6.8 7.2 2.4 4.4 3.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.1 1.9 5.6 9.6 5.3 7.2 7.6 9.8 7.9 -2.5 -4.4 -3.7 -2.5 -2.4 -0.4
Nucleus 0 5.7 4.0 7.2 10.9 11.1 15.5 13.4 18.4 2.5 4.3 13.3 13.3 13.8 14.1
Nuclear Periphery 2.9 -3.5 -3.3 -10.0 -11.3 -9.8 -14.7 -12.4 -16.8 0.3 -3.4 -10.4 -14.7 -16.8 -15.9
Nucleolus 1.4 1.2 1.4 2.5 2.7 1.8 1.7 3.0 2.4 0 0 0 0 3.3 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -5.3 -4.1 -6.2 -8.4 -6.5 -7.0 -8.2 -8.9 -9.7 -3.5 -4.7 -8.0 -3.2 -4.5 -4.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.5589 11.3035 11.1689 10.0896 10.3049 10.7621 8.7984 9.0559 8.2212 7.2612 7.4838 7.4015 9.3874 9.3233 8.2768 7.6379 6.7801 7.6105
Actin 0.0017 0 0.0004 0.0003 0.0001 0 0.009 0.0003 0.0143 0.1318 0.0001 0.0297 0.0109 0 0.005 0.0004 0.0068 0.0005
Bud 0.0001 0 0 0.0003 0 0 0.0006 0.0001 0.0002 0.0013 0 0.0005 0.0001 0 0.0001 0 0.0002 0
Bud Neck 0.0001 0 0 0.0001 0 0 0.0006 0.0003 0.0001 0.001 0 0.0001 0.0002 0 0.0007 0.0003 0.0003 0
Bud Periphery 0.0003 0 0.0002 0.0008 0 0 0.0007 0.0004 0.0003 0.0029 0.0001 0.0018 0.0002 0 0.0003 0 0.0003 0
Bud Site 0.0003 0 0 0.0008 0 0 0.0038 0.0001 0.0011 0.0032 0 0.0002 0.0012 0 0.0008 0 0.0009 0
Cell Periphery 0.0002 0 0.0001 0.0003 0 0 0.0002 0.0002 0.0001 0.0004 0 0 0 0 0.0001 0 0.0001 0
Cytoplasm 0.0005 0.0001 0.0001 0.0005 0 0 0.0032 0.0002 0.0046 0.0027 0 0.0003 0.0003 0 0.0004 0.0127 0.0065 0
Cytoplasmic Foci 0.0008 0 0.0002 0.0003 0 0 0.0023 0.0002 0.0018 0.0064 0 0.0002 0.0177 0 0.0008 0.0001 0.0086 0.0012
Eisosomes 0.0001 0 0 0 0 0 0.0002 0 0.0001 0.0005 0 0.0001 0.0001 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0025 0.0007 0.0059 0.0023 0.0007 0.0003 0.0026 0.001 0.0056 0.009 0.0006 0.0018 0.0007 0.0008 0.0016 0.0017 0.0064 0.0006
Endosome 0.0027 0.0001 0.0022 0.0057 0.0001 0.0001 0.0121 0.0016 0.0098 0.0508 0.0001 0.002 0.0058 0 0.001 0.0004 0.0215 0.0008
Golgi 0.0018 0 0.0009 0.0004 0 0 0.0022 0.0003 0.0043 0.0144 0 0.0012 0.0034 0 0.0005 0 0.0076 0.0003
Lipid Particles 0.0124 0 0.0051 0.0011 0.0001 0 0.0027 0.0014 0.0025 0.01 0.0001 0.0006 0.0137 0 0.0019 0 0.0176 0.0022
Mitochondria 0.0076 0.0014 0.0031 0.0088 0.0004 0.0003 0.0058 0.0029 0.0066 0.241 0.0042 0.0054 0.0038 0.0004 0.0055 0.0007 0.007 0.0026
None 0.0003 0 0.0002 0.0002 0 0 0.003 0.0001 0.0004 0.0021 0.0001 0.0003 0.0005 0 0.0003 0.0108 0.004 0.0001
Nuclear Periphery 0.883 0.8723 0.89 0.8128 0.9639 0.97 0.7676 0.8912 0.8722 0.4386 0.9161 0.9139 0.8846 0.9165 0.9101 0.9092 0.8517 0.9693
Nucleolus 0.0026 0.0002 0.0001 0.0023 0.0002 0.0001 0.0034 0.0009 0.0002 0.0019 0.0001 0.0003 0.0002 0.0001 0.0011 0.0001 0.0009 0.0001
Nucleus 0.0375 0.0896 0.028 0.111 0.0054 0.0103 0.1329 0.032 0.0187 0.0151 0.002 0.0095 0.0095 0.0165 0.0075 0.0118 0.0157 0.0045
Peroxisomes 0.0003 0 0 0.0002 0 0 0.0009 0 0.0005 0.003 0 0.0005 0.0084 0 0.0002 0 0.0023 0.0003
Punctate Nuclear 0.0016 0.0001 0.0002 0.0002 0.0003 0.0001 0.0097 0.0002 0.0019 0.0059 0 0.001 0.0038 0 0.0003 0.0009 0.0077 0.0007
Vacuole 0.0026 0.0005 0.0026 0.0151 0.0002 0.0002 0.0023 0.0064 0.0016 0.0075 0.0003 0.0005 0.0004 0.0005 0.0015 0.0004 0.0018 0.0002
Vacuole Periphery 0.0411 0.035 0.0606 0.0364 0.0287 0.0186 0.0343 0.0602 0.0531 0.0506 0.076 0.0301 0.0346 0.065 0.0602 0.0503 0.0319 0.0166

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 25.097 23.9825 20.6664 20.2927 20.1969 18.1637 30.3108 19.0059 21.9087 21.9927
Translational Efficiency 0.9492 1.3444 1.151 1.3187 1.2906 1.5514 0.9996 1.8256 1.3396 1.2942

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
850 1384 2102 120 2109 14 196 13 2959 1398 2298 133

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 684.44 798.48 1008.62 1138.21 797.58 319.28 917.23 351.78 765.08 793.68 1000.83 1061.34
Standard Deviation 128.12 134.61 147.75 179.81 109.06 14.84 104.99 4.10 125.75 142.19 146.83 289.34
Intensity Change Log 2 — 0.222332 0.559387 0.733771 — -1.320807 0.201654 -1.180956 — -0.406954 0.377930 0.007738

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000246 0.000180 0.000272 0.000318 0.000099 0.000013 0.000276 0.000103 0.000141 0.000178 0.000272 0.000297
Bud Neck 0.000365 0.000669 0.001935 0.002178 0.000532 0.000002 0.000556 0.000002 0.000484 0.000662 0.001817 0.001965
Bud Site 0.000125 0.000715 0.000628 0.000610 0.000345 0.000006 0.000138 0.000009 0.000281 0.000708 0.000586 0.000551
Cell Periphery 0.000139 0.000104 0.000033 0.000026 0.000119 0.000031 0.000035 0.000175 0.000125 0.000103 0.000033 0.000040
Cytoplasm 0.022998 0.032638 0.003467 0.000690 0.016356 0.000013 0.002558 0.000015 0.018264 0.032312 0.003390 0.000624
Cytoplasmic Foci 0.004258 0.005205 0.000434 0.000189 0.002161 0.000006 0.000579 0.000010 0.002763 0.005153 0.000447 0.000171
Eisosomes 0.000021 0.000016 0.000003 0.000003 0.000006 0.000028 0.000016 0.001052 0.000010 0.000016 0.000004 0.000105
Endoplasmic Reticulum 0.021635 0.041932 0.010947 0.011951 0.040493 0.000000 0.015462 0.000000 0.035076 0.041512 0.011332 0.010783
Endosome 0.002709 0.004277 0.000931 0.001032 0.002600 0.000000 0.001010 0.000000 0.002631 0.004234 0.000938 0.000931
Golgi 0.000199 0.000856 0.000237 0.000188 0.000077 0.000003 0.000113 0.000001 0.000112 0.000847 0.000226 0.000170
Lipid Particles 0.013215 0.012855 0.000410 0.000204 0.005020 0.000011 0.001840 0.000010 0.007374 0.012726 0.000532 0.000185
Mitochondria 0.007255 0.005759 0.002946 0.002945 0.003920 0.000005 0.006221 0.000006 0.004878 0.005701 0.003226 0.002658
Mitotic Spindle 0.002053 0.002859 0.008801 0.029536 0.000365 0.000235 0.010312 0.000128 0.000850 0.002833 0.008930 0.026662
None 0.026218 0.011511 0.000919 0.000114 0.004851 0.999575 0.001383 0.998319 0.010989 0.021405 0.000958 0.097683
Nuclear Periphery 0.461928 0.550961 0.768932 0.721621 0.735410 0.000000 0.665175 0.000000 0.656850 0.545444 0.760082 0.651087
Nuclear Periphery Foci 0.153238 0.192789 0.085366 0.172967 0.119345 0.000015 0.147829 0.000000 0.129081 0.190859 0.090694 0.156060
Nucleolus 0.051576 0.016041 0.019683 0.011944 0.006862 0.000014 0.018449 0.000001 0.019706 0.015880 0.019578 0.010777
Nucleus 0.226415 0.108750 0.087388 0.019856 0.048524 0.000006 0.122117 0.000003 0.099625 0.107661 0.090350 0.017915
Peroxisomes 0.000999 0.001142 0.000135 0.000271 0.000277 0.000037 0.000658 0.000166 0.000484 0.001131 0.000179 0.000260
Vacuole 0.002753 0.006545 0.003559 0.012508 0.007666 0.000000 0.004392 0.000000 0.006255 0.006479 0.003630 0.011286
Vacuole Periphery 0.001656 0.004196 0.002974 0.010850 0.004974 0.000000 0.000881 0.000000 0.004021 0.004154 0.002795 0.009789

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.56 -1.50 -0.98 -1.71 -0.40 NaN NaN NaN NaN NaN -1.84 -8.43 -2.35 -1.59 -0.05
Bud Neck -2.07 -7.75 -2.53 -2.12 -0.13 NaN NaN NaN NaN NaN -1.16 -7.24 -2.29 -2.03 0.05
Bud Site -1.68 -1.26 -1.89 0.15 -0.05 NaN NaN NaN NaN NaN -1.21 -0.88 -1.18 0.29 0.04
Cell Periphery 1.61 5.29 5.43 6.31 0.87 NaN NaN NaN NaN NaN 1.40 7.42 5.67 4.65 -0.55
Cytoplasm -2.31 7.23 8.33 11.14 5.56 NaN NaN NaN NaN NaN -4.42 10.33 12.58 11.18 6.07
Cytoplasmic Foci -1.02 4.82 5.44 5.58 0.64 NaN NaN NaN NaN NaN -2.55 4.71 6.10 5.61 0.84
Eisosomes 2.05 11.63 11.22 8.42 0.82 NaN NaN NaN NaN NaN -3.78 7.40 -1.81 -1.69 -1.92
Endoplasmic Reticulum -7.08 6.35 3.25 8.48 -0.31 NaN NaN NaN NaN NaN -2.24 14.43 8.79 9.15 0.32
Endosome -2.42 4.16 3.13 5.32 -0.48 NaN NaN NaN NaN NaN -2.98 6.97 4.60 5.61 -0.07
Golgi -2.58 -0.25 -0.16 2.38 0.12 NaN NaN NaN NaN NaN -2.92 -0.85 -0.95 2.47 0.20
Lipid Particles 0.01 9.58 9.93 8.92 0.73 NaN NaN NaN NaN NaN -3.67 10.96 12.60 8.93 1.41
Mitochondria 1.19 3.83 3.25 2.88 0.09 NaN NaN NaN NaN NaN -1.18 2.69 2.73 3.31 0.78
Mitotic Spindle -0.46 -4.64 -2.27 -2.23 -1.72 NaN NaN NaN NaN NaN -2.29 -6.21 -2.37 -2.21 -1.60
None 3.87 7.18 7.45 7.49 2.62 NaN NaN NaN NaN NaN -3.16 8.07 -3.35 -2.93 -3.75
Nuclear Periphery -5.66 -21.66 -10.10 -6.99 1.88 NaN NaN NaN NaN NaN 10.02 -11.03 0.30 -3.62 3.71
Nuclear Periphery Foci -4.24 8.94 -1.26 1.38 -6.19 NaN NaN NaN NaN NaN -8.75 9.15 -1.94 2.45 -4.80
Nucleolus 8.55 7.77 7.38 1.05 2.09 NaN NaN NaN NaN NaN 1.76 -0.27 2.45 1.41 2.58
Nucleus 9.30 11.51 17.36 11.37 10.99 NaN NaN NaN NaN NaN -1.21 0.81 13.46 11.95 12.51
Peroxisomes -0.74 8.76 6.37 3.46 -1.98 NaN NaN NaN NaN NaN -2.71 5.92 3.14 3.51 -1.24
Vacuole -4.41 -1.80 -2.25 -1.42 -2.00 NaN NaN NaN NaN NaN -0.27 2.52 -1.34 -1.27 -1.83
Vacuole Periphery -2.77 -3.03 -2.20 -1.58 -1.89 NaN NaN NaN NaN NaN -0.13 2.33 -1.53 -1.47 -1.85
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity
Localization
Cell Percentages nuclear periphery (84%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pct1

Pct1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pct1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available