Standard name
Human Ortholog
Description ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.98 0.96 0.95 0.88 0.81 0.78 0.72 0.76 0.7 0.68 1.0 1.0 0.98 0.96 0.94 0.93 0.96 0.94 0.93 0.77 0.77 0.72
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.05 0.06 0.06 0 0.24 0.1 0.22 0.15 0 0 0 0 0 0 0 0 0 0.11 0.11 0.13
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.09 0.16 0.15 0.11 0.12 0.11 0.16 0 0 0 0.05 0.1 0.14 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 3 3 0 0 0 0 0 0 0 5 1 2 1 6
Bud 0 2 0 0 5 1 2 1 4 2 7 7 0 0 0 0 0 0 0 0 2 3 3 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 2
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 2 3 2 0 3 5 6 10 10 18 20 0 2 0 8 8 2 0 0 0 0 0 1
Cytoplasm 489 526 388 317 212 394 481 499 298 414 393 392 215 212 236 576 423 425 487 519 365 206 213 233
Endoplasmic Reticulum 2 5 2 2 0 4 2 18 4 12 7 10 0 1 1 16 11 10 0 1 1 3 2 7
Endosome 0 0 1 0 1 3 0 0 1 0 0 0 0 0 2 2 2 1 4 6 4 5 3 7
Golgi 1 1 2 0 0 0 1 0 0 0 0 0 0 0 0 1 1 1 1 1 2 0 1 1
Mitochondria 4 10 1 6 12 26 37 28 100 56 124 88 0 0 1 10 6 1 0 6 3 28 29 43
Nucleus 7 2 0 4 2 8 14 26 12 16 20 16 2 1 0 4 7 3 1 2 1 2 1 0
Nuclear Periphery 1 2 0 0 0 0 0 0 0 3 1 3 0 0 0 0 0 0 0 0 0 1 2 3
Nucleolus 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 1
SpindlePole 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 2 1 4
Vac/Vac Membrane 0 6 2 13 9 39 96 93 45 64 59 91 1 0 1 28 47 64 4 3 3 3 4 4
Unique Cell Count 501 542 394 331 224 447 594 638 416 545 560 574 216 213 240 598 451 455 510 556 394 268 276 326
Labelled Cell Count 506 556 399 346 241 478 638 672 474 577 632 630 218 216 241 645 505 508 510 556 394 268 276 326


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.7 6.2 7.2 6.8 5.9 6.7 7.0 7.5 6.7 7.6 7.3 7.6 7.1 7.0 7.1 8.5 10.3 10.3 7.4 7.6 7.7
Std Deviation (1e-4) 1.1 0.9 1.4 1.8 1.3 1.3 1.4 1.6 1.6 1.7 1.9 1.9 1.1 0.9 1.3 1.7 1.7 2.0 2.1 1.7 1.7
Intensity Change (Log2) – – – -0.07 -0.28 -0.09 -0.03 0.07 -0.1 0.09 0.03 0.09 -0.01 -0.04 -0.02 0.24 0.52 0.52 0.05 0.08 0.1

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 1.9 1.4 2.5 2.7 0 0 0 0 1.3 0
Cytoplasm -2.2 -2.7 -5.9 -8.3 -9.1 -10.6 -9.6 -11.2 -11.7 1.2 1.2 -0.1 -2.0 -3.5 -3.7
Endoplasmic Reticulum 0 0 0 0 2.6 0 2.1 0 0 0 0 0 2.5 2.3 2.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.6 4.8 3.9 10.2 6.3 9.9 8.0 0 0 0 0 0 0
Nucleus 0 0 0 3.1 4.1 3.4 3.4 3.8 3.3 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.2 0 5.5 8.1 7.6 6.3 6.6 6.2 8.0 0 0 0 3.8 6.2 7.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.04 4.095 3.1546 3.0957 2.5043 3.2337 5.8375 6.8256 6.8866 5.1404 6.2609 6.8568 3.9292 4.5547 4.334 4.0564 3.9572 4.3042
Actin 0.0358 0.0042 0.0069 0.0382 0.0432 0.0007 0.0011 0.006 0.0005 0.0013 0.0005 0.0038 0.0205 0.0018 0.0033 0.0097 0.0013 0.0028
Bud 0.0006 0.0017 0.0005 0.0004 0.0001 0.0001 0.0002 0.0002 0.0028 0.0011 0.0006 0.012 0.0005 0.0058 0.0017 0.0004 0.0001 0.0001
Bud Neck 0.0015 0.0001 0.0004 0.0003 0.0004 0.0011 0.0002 0.0001 0.0002 0.0004 0.0004 0.0064 0.0027 0.002 0.0005 0.0047 0.0002 0.0013
Bud Periphery 0.001 0.002 0.0006 0.0007 0.0002 0 0.0001 0.0001 0.0016 0.0006 0.0002 0.004 0.0007 0.0044 0.0013 0.0003 0.0001 0.0001
Bud Site 0.0026 0.001 0.0028 0.0005 0.0003 0.0001 0.0003 0.0006 0.0006 0.0003 0.0003 0.0005 0.0029 0.0114 0.0048 0.0044 0.0001 0.0002
Cell Periphery 0.0004 0.0002 0.0002 0 0.0001 0 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0002 0.0003 0.0002 0.0002 0 0
Cytoplasm 0.587 0.7838 0.6988 0.7168 0.6854 0.8217 0.8334 0.827 0.8135 0.9038 0.7941 0.7745 0.6077 0.7394 0.6798 0.6783 0.636 0.6967
Cytoplasmic Foci 0.0177 0.0028 0.01 0.0176 0.0177 0.0108 0.0037 0.0158 0.0049 0.0093 0.005 0.0054 0.0125 0.0073 0.0073 0.0076 0.0076 0.0111
Eisosomes 0.0004 0.0001 0.0001 0.0001 0.0005 0 0 0.0001 0 0 0 0 0.0002 0 0 0.0001 0.0002 0
Endoplasmic Reticulum 0.0048 0.0051 0.0023 0.0013 0.0013 0.002 0.0043 0.0014 0.0026 0.0028 0.0031 0.0033 0.0025 0.0014 0.0023 0.003 0.0012 0.0017
Endosome 0.0127 0.0012 0.0071 0.0017 0.0072 0.0017 0.0012 0.0017 0.0008 0.0046 0.0021 0.0036 0.0133 0.0015 0.0028 0.0025 0.0021 0.0035
Golgi 0.0062 0.0003 0.0019 0.0012 0.0059 0.0002 0.0001 0.001 0.0001 0.0003 0.0001 0.0002 0.002 0.0002 0.0009 0.0008 0.0003 0.0005
Lipid Particles 0.0082 0.0002 0.0051 0.0026 0.0191 0.0001 0.0001 0.0007 0.0001 0.0001 0 0.0001 0.0027 0.0001 0.001 0.0002 0.0019 0.0009
Mitochondria 0.0055 0.0003 0.0125 0.0006 0.0019 0.0001 0.0002 0.0002 0.0009 0.0002 0.0002 0.0003 0.0019 0.0003 0.0007 0.0003 0.0003 0.0003
None 0.2839 0.1929 0.2374 0.1755 0.1866 0.1575 0.1488 0.138 0.1579 0.0626 0.1824 0.1809 0.3133 0.2117 0.2788 0.2804 0.3389 0.2701
Nuclear Periphery 0.0016 0.0007 0.001 0.0004 0.0016 0.0005 0.0014 0.0004 0.0014 0.0016 0.002 0.0007 0.0029 0.001 0.0019 0.001 0.0022 0.0008
Nucleolus 0.0013 0.0001 0.0003 0 0.0003 0 0 0 0.0008 0 0 0 0.0006 0.0003 0.0002 0.0001 0.0004 0.0001
Nucleus 0.003 0.0022 0.002 0.0025 0.0014 0.0021 0.0031 0.002 0.0053 0.0078 0.007 0.0029 0.0041 0.0063 0.0054 0.0036 0.002 0.0037
Peroxisomes 0.0195 0.0002 0.0071 0.0383 0.0157 0.0003 0.0001 0.0036 0.0002 0.0001 0.0001 0.0001 0.0033 0.0005 0.0028 0.0004 0.0004 0.002
Punctate Nuclear 0.0034 0.0003 0.0011 0.0008 0.0106 0.0009 0.0008 0.0004 0.0051 0.0008 0.0009 0.0005 0.0038 0.0037 0.0033 0.0015 0.0043 0.0035
Vacuole 0.0019 0.0005 0.0014 0.0004 0.0003 0.0003 0.0007 0.0004 0.0005 0.0018 0.0008 0.0005 0.0014 0.0008 0.0009 0.0006 0.0004 0.0004
Vacuole Periphery 0.001 0.0001 0.0004 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0003 0.0002 0.0001 0.0004 0.0001 0.0002 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 10.1114 10.1688 11.7378 16.3515 11.4711 10.1058 15.4225 17.7341 20.1241 17.7399
Translational Efficiency 1.4234 0.8742 1.4673 1.4151 1.4564 2.4068 1.3408 1.218 1.4142 1.3156

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1580 506 1980 1944 2000 1897 2464 1344 3580 2403 4444 3288

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 727.52 804.25 1019.62 1010.58 806.15 949.18 1095.26 1161.09 771.45 918.66 1061.56 1072.10
Standard Deviation 94.82 172.43 157.97 139.67 112.87 124.24 164.57 173.17 112.29 148.12 165.98 171.08
Intensity Change Log 2 — 0.144657 0.486973 0.474125 — 0.235633 0.442153 0.526360 — 0.193192 0.463588 0.501817

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000191 0.000432 0.000256 0.003974 0.000382 0.000347 0.000107 0.001680 0.000298 0.000365 0.000174 0.003036
Bud Neck 0.009368 0.006354 0.003732 0.005534 0.002504 0.010063 0.002050 0.003313 0.005533 0.009282 0.002799 0.004626
Bud Site 0.006067 0.015609 0.011008 0.023313 0.003914 0.013580 0.005614 0.034711 0.004864 0.014007 0.008018 0.027972
Cell Periphery 0.000124 0.000099 0.000083 0.000112 0.000064 0.000082 0.000056 0.000077 0.000090 0.000086 0.000068 0.000098
Cytoplasm 0.579681 0.638171 0.710568 0.555764 0.738088 0.674062 0.717321 0.653022 0.668177 0.666504 0.714312 0.595519
Cytoplasmic Foci 0.231546 0.118693 0.010421 0.021305 0.073096 0.119910 0.006755 0.017546 0.143026 0.119653 0.008389 0.019768
Eisosomes 0.000104 0.000045 0.000016 0.000025 0.000023 0.000050 0.000010 0.000013 0.000059 0.000049 0.000013 0.000020
Endoplasmic Reticulum 0.001231 0.000926 0.000922 0.001406 0.000899 0.000586 0.000527 0.000856 0.001045 0.000658 0.000703 0.001181
Endosome 0.008719 0.013451 0.002252 0.013463 0.002592 0.009176 0.000797 0.007506 0.005296 0.010076 0.001445 0.011028
Golgi 0.003882 0.001895 0.001367 0.007991 0.000632 0.002483 0.000065 0.006847 0.002067 0.002359 0.000645 0.007523
Lipid Particles 0.004312 0.001647 0.000512 0.001861 0.001183 0.001450 0.000353 0.000580 0.002564 0.001491 0.000424 0.001337
Mitochondria 0.002378 0.002618 0.000484 0.004576 0.000832 0.003735 0.000313 0.002330 0.001514 0.003500 0.000389 0.003658
Mitotic Spindle 0.000673 0.004259 0.010211 0.093442 0.002432 0.009046 0.005534 0.100412 0.001655 0.008038 0.007618 0.096291
None 0.004145 0.007762 0.008201 0.007290 0.003530 0.002667 0.009210 0.006359 0.003801 0.003740 0.008760 0.006910
Nuclear Periphery 0.000172 0.000328 0.000671 0.000874 0.000277 0.000171 0.000498 0.003094 0.000230 0.000204 0.000575 0.001782
Nuclear Periphery Foci 0.000829 0.001376 0.001244 0.002309 0.000924 0.000462 0.001268 0.004845 0.000882 0.000654 0.001257 0.003346
Nucleolus 0.000691 0.001467 0.000452 0.000675 0.000308 0.000400 0.000143 0.000177 0.000477 0.000625 0.000281 0.000472
Nucleus 0.098381 0.078171 0.157606 0.089376 0.128549 0.077508 0.195153 0.084136 0.115234 0.077647 0.178424 0.087234
Peroxisomes 0.002754 0.003700 0.000298 0.003487 0.000578 0.003465 0.000130 0.000683 0.001538 0.003514 0.000205 0.002341
Vacuole 0.043734 0.101757 0.079244 0.155286 0.038773 0.069538 0.054026 0.068833 0.040963 0.076322 0.065262 0.119948
Vacuole Periphery 0.001020 0.001240 0.000451 0.007938 0.000421 0.001221 0.000068 0.002979 0.000685 0.001225 0.000239 0.005911

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.71 -0.64 -2.03 -1.39 -1.95 0.18 1.01 -0.76 -1.03 -1.65 -0.49 0.87 -1.97 -1.86 -2.51
Bud Neck 2.83 6.36 7.17 3.37 0.02 -8.88 0.58 0.72 9.66 0.05 -4.87 5.77 6.02 9.38 -0.56
Bud Site -4.28 -1.62 -4.54 2.11 -1.96 -6.74 -0.67 -4.50 1.33 -4.17 -7.76 -1.63 -6.63 2.34 -4.85
Cell Periphery 2.86 7.49 7.82 4.34 1.43 -3.80 1.38 -0.88 3.45 -2.83 1.16 6.79 5.58 4.69 -0.18
Cytoplasm -2.84 -2.57 7.41 7.49 10.24 9.04 19.22 20.63 11.36 5.76 1.31 10.94 21.52 17.25 12.31
Cytoplasmic Foci 13.63 41.20 40.62 16.23 -2.58 -11.14 27.91 25.39 31.13 -6.00 5.60 44.67 43.14 35.10 -6.20
Eisosomes 8.08 15.25 14.79 5.50 -2.25 -10.28 6.10 4.06 14.99 -3.82 2.76 15.88 14.39 14.59 -5.36
Endoplasmic Reticulum 1.14 -0.07 1.86 1.01 3.35 1.65 1.84 3.37 0.24 3.15 2.31 0.97 2.89 -0.51 3.31
Endosome -2.19 12.09 6.29 4.98 -4.01 -8.34 8.91 2.24 8.97 -3.01 -6.06 14.41 5.21 8.82 -5.33
Golgi 3.55 5.10 2.72 -0.39 -2.03 -4.30 3.66 -1.20 2.45 -2.81 -0.49 5.89 1.10 1.40 -3.37
Lipid Particles 7.78 14.15 10.43 1.93 -2.11 -1.38 5.31 1.97 3.00 -7.62 5.77 14.68 9.19 2.75 -3.50
Mitochondria 0.02 3.76 1.45 0.56 -3.99 -3.07 1.48 0.70 3.52 -1.59 -2.32 3.86 1.09 2.91 -4.39
Mitotic Spindle -2.83 -6.80 -11.96 -10.16 -8.23 -3.62 -4.01 -8.11 -5.85 -6.48 -4.60 -7.51 -14.23 -10.52 -10.75
None -1.72 -3.60 -2.24 0.76 1.01 1.52 -11.80 -6.65 -7.06 2.90 0.41 -10.49 -5.57 -4.49 3.13
Nuclear Periphery -2.80 -25.86 -15.82 -10.11 -1.53 2.29 -14.18 -3.34 -3.67 -1.19 0.49 -25.71 -7.83 -8.00 -1.85
Nuclear Periphery Foci -3.55 -4.10 -2.50 1.05 0.44 4.31 -4.30 -2.99 -4.30 -1.41 2.37 -5.87 -3.78 -4.97 -0.78
Nucleolus -1.67 2.27 2.26 2.45 -0.34 -1.40 1.79 1.46 4.37 -1.42 -1.19 2.84 2.05 2.86 -1.26
Nucleus 2.78 -21.69 -7.71 -7.94 15.46 13.31 -24.88 -2.89 -14.57 19.74 11.91 -32.79 -6.40 -17.75 26.07
Peroxisomes -1.31 11.06 4.59 3.96 -2.57 -7.13 4.56 3.54 8.32 -2.74 -5.54 11.71 3.99 7.43 -2.89
Vacuole -9.76 -20.14 -35.88 -14.96 -16.83 -11.27 -17.29 -26.28 -20.43 -15.00 -14.86 -26.37 -44.43 -31.41 -23.71
Vacuole Periphery -0.52 5.84 -1.80 -1.55 -3.13 -3.23 3.96 -0.46 2.40 -2.51 -2.56 6.97 -2.12 -0.65 -3.68
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases; null mutant is sensitive to expression of the top1-T722A allele
Localization
Cell Percentages cytoplasm (93%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Tda10

Tda10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tda10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available