Standard name
Human Ortholog
Description Phosphoserine phosphatase of the phosphoglycerate pathway; involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 1.0 1.0 0.98 0.98 0.96 0.89 0.84 0.9 0.88 0.89 0.83 0.99 0.99 0.99 1.0 0.99 0.95 0.96 0.94 0.92 0.97 0.97 0.96
Endoplasmic Reticulum 0 0 0 0 0 0 0.08 0.11 0.06 0.06 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 3 2 2 2 2 5 0 1 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 1 0 2 1 3 2 1 1 1 0 1 0 0 0 0 0 0 0 4 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 5 10 11 16 25 19 20 4 17 2 2 8 1 2 4 0 0 0 0 0 0
Cytoplasm 120 70 69 351 537 442 591 605 446 434 329 401 490 713 799 73 145 97 116 70 91 254 587 624
Endoplasmic Reticulum 1 0 0 1 5 13 52 77 28 31 9 32 3 4 1 1 4 2 0 0 0 0 3 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 1 1 0 1 1 0 0 1 0 0 0 1 0 0 0 0 0 0
Nucleus 0 0 0 4 1 5 10 14 5 11 3 8 0 0 0 0 0 0 0 1 1 2 2 2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 1 0 0 2 5 2 12 17 12 16 25 45 1 0 2 1 1 2 0 2 1 0 1 6
Unique Cell Count 122 70 69 358 549 460 667 718 498 496 368 484 494 717 804 73 147 102 121 75 99 262 608 647
Labelled Cell Count 122 70 69 363 559 473 687 742 516 517 374 509 497 722 812 76 153 107 121 75 99 262 608 647


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 32.2 25.5 33.5 33.1 30.6 25.2 22.7 22.9 20.4 19.9 18.1 18.6 41.1 44.0 40.5 56.1 57.8 52.2 35.7 36.8 37.9
Std Deviation (1e-4) 6.1 9.7 7.2 6.6 5.7 4.3 4.2 4.4 4.0 4.0 3.7 3.8 7.9 9.8 9.0 15.5 17.5 19.5 6.9 8.3 8.6
Intensity Change (Log2) – – – -0.02 -0.13 -0.41 -0.56 -0.55 -0.71 -0.75 -0.89 -0.85 0.3 0.39 0.27 0.74 0.79 0.64 0.09 0.13 0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000204060WT3HU80HU120HU1600204060WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30204060WT1AF100AF140AF1800204060
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.2 -1.2 -1.7 -3.0 -3.6 -2.8 -3.1 -2.8 -3.7 -0.8 -0.6 -0.7 0 -1.0 -1.9
Endoplasmic Reticulum 0 0 0 0 2.9 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 2.6 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 28.4441 33.9015 31.0926 29.3493 31.4311 31.521 26.1088 37.6052 35.2668 36.2875 28.2837 35.4654 32.889 37.6705 35.7788 33.7177 34.7964 34.8447
Actin 0.0061 0.0001 0.0066 0.0001 0.0153 0.0002 0.0105 0.0001 0.0008 0.0001 0.0041 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0006
Bud 0.0003 0.0001 0.0005 0.0001 0.0001 0 0.0007 0 0.0006 0 0.0005 0.0001 0.0001 0.0011 0.0001 0 0 0.0003
Bud Neck 0.0004 0.0001 0.0005 0.0003 0.0005 0.0004 0.0013 0.0001 0.0002 0.0002 0.0006 0.0004 0.0001 0.0001 0.0001 0.0001 0.0002 0.0006
Bud Periphery 0.0002 0 0.0004 0.0001 0.0003 0 0.0007 0 0.0007 0 0.0004 0 0 0.0002 0 0 0 0.0001
Bud Site 0.0003 0.0001 0.0003 0.0001 0.0003 0 0.0018 0 0.0003 0 0.0009 0 0.0001 0.0002 0 0 0 0
Cell Periphery 0.0001 0 0.0003 0.0002 0.0002 0 0.0002 0 0.0001 0 0.0002 0 0.0001 0 0 0 0 0
Cytoplasm 0.9258 0.99 0.9594 0.9387 0.9305 0.9687 0.8529 0.9947 0.9651 0.99 0.8597 0.9744 0.9575 0.9904 0.9851 0.9878 0.9913 0.9692
Cytoplasmic Foci 0.0072 0.0002 0.0031 0.0053 0.0006 0.0019 0.0158 0.0001 0.0014 0.0002 0.024 0.0005 0.0004 0.0004 0.0014 0.0001 0.0003 0.0011
Eisosomes 0.0001 0 0.0001 0 0.0005 0 0.0004 0 0 0 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0019 0.0003 0.0008 0.0011 0.0042 0.0017 0.0056 0.0001 0.0006 0.0002 0.0035 0.0007 0.0007 0.0003 0.0001 0.0001 0.0001 0.0009
Endosome 0.0026 0.0001 0.0023 0.0023 0.0105 0.0016 0.0157 0 0.0018 0 0.0031 0.0004 0.001 0.0001 0.0001 0 0.0001 0.0006
Golgi 0.0011 0 0.0003 0.0002 0.0039 0.0001 0.0019 0 0.0005 0 0.0021 0 0 0 0 0 0 0.0001
Lipid Particles 0.0031 0 0.0011 0.0055 0.0032 0.0005 0.0051 0 0.0006 0 0.0146 0 0 0 0 0 0 0
Mitochondria 0.0025 0.0001 0.0044 0.0027 0.0027 0.0001 0.0083 0 0.0113 0 0.0037 0.0001 0.0002 0.0001 0.0001 0 0.0001 0.0003
None 0.0023 0.0001 0.0009 0.0058 0.002 0.0003 0.0102 0.0001 0.0009 0.0001 0.0075 0.0002 0.002 0.0004 0.0005 0.0001 0.0001 0.0003
Nuclear Periphery 0.0056 0.0012 0.0015 0.0061 0.0088 0.0039 0.0161 0.0004 0.0013 0.0012 0.0095 0.0032 0.0077 0.001 0.0011 0.0014 0.0006 0.0047
Nucleolus 0.0028 0 0.0002 0.0027 0.0002 0 0.0028 0 0.0004 0 0.0017 0 0.0002 0 0 0 0 0
Nucleus 0.0273 0.0072 0.0113 0.0196 0.0129 0.018 0.0289 0.0043 0.0101 0.0078 0.0174 0.0187 0.0257 0.0051 0.0105 0.0102 0.0071 0.0202
Peroxisomes 0.0042 0 0.0003 0.0003 0.0003 0 0.0023 0 0.0003 0 0.0315 0 0 0 0 0 0 0
Punctate Nuclear 0.0037 0.0001 0.0004 0.0021 0.0007 0.0017 0.012 0 0.0005 0.0001 0.012 0.0002 0.0008 0.0001 0.0005 0 0 0.0002
Vacuole 0.0017 0.0002 0.0044 0.0037 0.0008 0.0005 0.0051 0 0.0018 0.0001 0.002 0.0008 0.0024 0.0003 0.0001 0.0001 0.0001 0.0005
Vacuole Periphery 0.0007 0 0.0008 0.0029 0.0012 0.0001 0.0017 0 0.0007 0 0.0009 0.0002 0.0008 0 0 0 0 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 63.4754 49.8491 40.1383 43.7563 54.6094 56.9184 58.1772 49.2178 41.5595 56.0132
Translational Efficiency 1.5063 1.7856 1.6697 1.2399 1.3555 1.489 1.5183 1.6713 1.741 1.6501

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1321 289 255 620 1268 1794 250 358 2589 2083 505 978

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2563.58 2940.16 2586.87 2402.77 2494.60 2823.25 2764.93 2547.47 2529.80 2839.47 2675.02 2455.74
Standard Deviation 476.77 546.53 473.03 429.57 454.15 515.81 391.41 497.10 467.10 521.75 443.57 460.75
Intensity Change Log 2 — 0.197735 0.013048 -0.093461 — 0.178548 0.148434 0.030257 — 0.188304 0.081406 -0.031120

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000146 0.000178 0.000217 0.000272 0.000150 0.000103 0.000265 0.012486 0.000148 0.000114 0.000241 0.004743
Bud Neck 0.000418 0.001055 0.001696 0.002692 0.000624 0.000357 0.002494 0.004573 0.000519 0.000454 0.002091 0.003381
Bud Site 0.000844 0.001844 0.005952 0.005150 0.000817 0.000861 0.002022 0.031465 0.000830 0.000997 0.004006 0.014783
Cell Periphery 0.000340 0.000737 0.000927 0.000326 0.000316 0.000133 0.000616 0.000514 0.000328 0.000216 0.000773 0.000395
Cytoplasm 0.772819 0.679708 0.691537 0.625926 0.749281 0.760349 0.560334 0.648232 0.761291 0.749160 0.626585 0.634091
Cytoplasmic Foci 0.004556 0.017724 0.021979 0.018152 0.005434 0.003849 0.017617 0.020394 0.004986 0.005774 0.019819 0.018972
Eisosomes 0.000001 0.000002 0.000003 0.000004 0.000001 0.000001 0.000003 0.000017 0.000001 0.000001 0.000003 0.000009
Endoplasmic Reticulum 0.000074 0.000591 0.000100 0.000351 0.000109 0.000124 0.000077 0.000181 0.000091 0.000189 0.000088 0.000289
Endosome 0.000074 0.001296 0.000292 0.011892 0.000129 0.000262 0.000184 0.004476 0.000101 0.000406 0.000238 0.009177
Golgi 0.000781 0.003363 0.001135 0.006321 0.000873 0.000961 0.000404 0.031315 0.000826 0.001294 0.000773 0.015470
Lipid Particles 0.000418 0.000758 0.001439 0.001902 0.000440 0.000269 0.001291 0.002855 0.000429 0.000337 0.001366 0.002251
Mitochondria 0.000094 0.000092 0.000545 0.000660 0.000132 0.000219 0.000202 0.013636 0.000113 0.000201 0.000375 0.005410
Mitotic Spindle 0.000226 0.000278 0.000631 0.046934 0.000732 0.002335 0.001344 0.005213 0.000474 0.002050 0.000984 0.031662
None 0.015027 0.019091 0.012781 0.013292 0.012423 0.020203 0.012531 0.009097 0.013752 0.020049 0.012657 0.011757
Nuclear Periphery 0.000062 0.000114 0.000194 0.000434 0.000119 0.000090 0.000407 0.000657 0.000090 0.000093 0.000300 0.000516
Nuclear Periphery Foci 0.001740 0.002138 0.001921 0.004092 0.002369 0.001511 0.002230 0.002757 0.002048 0.001598 0.002074 0.003604
Nucleolus 0.000067 0.000068 0.000099 0.000110 0.000076 0.000123 0.000119 0.000106 0.000071 0.000115 0.000109 0.000109
Nucleus 0.198600 0.261463 0.232574 0.205983 0.220872 0.204636 0.372986 0.157219 0.209508 0.212521 0.302085 0.188133
Peroxisomes 0.000008 0.000028 0.000025 0.000255 0.000009 0.000011 0.000020 0.000842 0.000008 0.000013 0.000023 0.000470
Vacuole 0.003582 0.007360 0.021090 0.042609 0.004446 0.002926 0.024780 0.040975 0.004005 0.003541 0.022917 0.042011
Vacuole Periphery 0.000124 0.002112 0.004863 0.012641 0.000648 0.000678 0.000072 0.012989 0.000381 0.000877 0.002491 0.012768

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.77 -3.08 -3.94 -0.46 -0.54 2.52 -6.25 -1.55 -1.59 -1.31 1.52 -6.84 -1.70 -1.75 -1.27
Bud Neck -4.61 -7.74 -10.07 -3.64 0.50 3.22 -9.34 -6.02 -6.83 4.08 0.09 -11.55 -10.88 -10.90 4.19
Bud Site -2.80 -5.22 -12.59 -4.60 0.95 -0.30 -8.77 -4.11 -4.09 -2.28 -1.54 -8.82 -6.58 -6.26 -1.49
Cell Periphery -4.35 -6.20 -1.47 3.77 5.67 4.36 -7.87 -3.30 -6.50 5.64 2.59 -9.93 -3.35 -5.80 8.31
Cytoplasm 8.66 9.08 15.04 3.23 1.68 -2.08 19.15 7.38 8.76 -9.68 2.69 18.61 15.91 13.95 -5.61
Cytoplasmic Foci -4.87 -8.72 -8.26 0.84 4.99 2.17 -8.47 -9.63 -10.37 1.61 -2.34 -12.13 -12.30 -10.53 5.25
Eisosomes -3.25 -6.30 -11.85 -4.57 -1.25 2.40 -8.84 -5.28 -5.55 1.06 -0.34 -10.65 -10.09 -9.93 0.92
Endoplasmic Reticulum -0.92 0.25 -1.62 0.82 -1.39 0.20 -2.36 2.58 0.91 4.33 -0.89 -1.30 -0.12 0.84 1.05
Endosome -1.05 -1.83 -2.52 -0.63 -2.29 -1.11 -5.48 -1.86 -1.50 -0.72 -1.66 -4.91 -2.90 -2.22 -2.32
Golgi -1.34 0.46 -0.50 1.18 -0.72 -0.10 0.77 -1.10 -1.08 -1.14 -0.98 0.76 -1.18 -0.84 -1.28
Lipid Particles -3.23 -3.64 -8.98 -4.00 1.13 1.79 -7.52 -6.22 -6.70 2.09 0.22 -6.90 -10.75 -10.61 2.26
Mitochondria -0.05 -0.96 -1.73 -1.68 0.47 -0.64 -6.46 -1.23 -1.17 -1.11 -0.81 -1.98 -1.31 -1.13 -0.98
Mitotic Spindle -0.54 -3.69 -3.48 -3.45 -3.22 -1.60 -2.58 -1.81 0.20 1.02 -2.18 -3.42 -3.61 -2.69 -2.83
None -0.36 4.62 7.18 2.86 1.22 -5.38 2.86 5.42 13.85 2.30 -4.81 5.37 8.62 12.89 2.22
Nuclear Periphery -5.41 -9.75 -14.36 -9.31 -2.84 1.68 -11.41 -5.06 -5.82 6.95 -0.37 -13.05 -12.50 -11.62 5.25
Nuclear Periphery Foci -2.15 -3.86 -2.86 -0.06 1.10 2.39 -3.46 -1.27 -4.02 2.85 1.60 -4.87 -2.65 -3.75 3.02
Nucleolus -0.55 -1.59 -3.57 -5.99 -2.99 -0.90 -9.42 -2.10 0.44 7.39 -1.03 -6.67 -4.50 -0.19 3.41
Nucleus -5.76 -1.32 2.64 7.00 2.81 2.66 -9.36 9.58 8.40 14.71 -0.86 -7.46 8.13 8.69 11.77
Peroxisomes -1.34 -4.73 -3.39 -1.70 -2.09 -0.27 -8.40 -2.17 -2.16 -1.41 -1.57 -9.40 -3.33 -3.17 -1.98
Vacuole -4.52 -8.59 -18.40 -16.17 -7.75 2.22 -9.56 -14.25 -14.47 -3.02 -0.98 -12.67 -23.23 -23.09 -7.18
Vacuole Periphery -1.07 -0.97 -1.30 -0.03 -0.01 -0.00 1.10 -0.89 -0.92 -1.35 -1.05 -0.66 -1.49 -1.02 -0.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Phosphoserine phosphatase of the phosphoglycerate pathway; involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Ser2

Ser2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ser2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available