Standard name
Human Ortholog
Description Ribosomal 40S subunit protein S0A; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication;
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0.06 0.05 0.05 0.07 0 0 0 0.06 0.05 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 0.92 0.95 0.91 0.83 0.64 0.58 0.54 0.54 0.48 0.48 0.97 0.96 0.97 0.94 0.97 0.95 0.89 0.9 0.84 0.88 0.96 0.88
Endoplasmic Reticulum 0 0 0 0 0 0.08 0.13 0.1 0.18 0.19 0.14 0.19 0 0 0 0.05 0 0.05 0 0 0.09 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.09 0.12 0.31 0.28 0.29 0.34 0.45 0.39 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.09 0.05 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 1 5 10 12 10 5 7 16 0 0 0 2 0 1 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 12 5 7 7 12 14 15 12 11 16 7 4 6 17 18 10 0 0 2 0 0 0
Cytoplasm 82 100 226 169 191 185 198 197 131 125 100 106 155 136 168 286 327 285 78 93 220 37 109 84
Endoplasmic Reticulum 0 1 11 4 7 18 39 35 44 43 30 42 4 4 6 15 5 16 3 2 23 0 1 4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Golgi 1 0 1 0 0 1 3 19 4 6 1 2 0 0 1 3 0 1 0 0 1 0 0 0
Mitochondria 1 1 5 4 18 26 97 93 70 78 94 85 0 0 0 3 3 1 1 1 5 0 0 0
Nucleus 0 0 0 0 0 1 1 2 0 1 0 1 2 1 0 0 0 2 0 2 0 1 0 0
Nuclear Periphery 0 0 1 0 0 1 1 0 0 2 2 3 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 2 0 5 1 7 31 13 10 12 7 0 0 6 8 6 9 1 1 2 1 0 2
Unique Cell Count 83 102 245 177 210 223 310 338 244 230 209 219 159 142 174 305 337 301 88 104 261 43 114 97
Labelled Cell Count 84 102 259 183 229 245 368 404 288 283 258 278 168 145 187 335 359 326 88 104 261 43 114 97


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.3 12.3 14.7 15.6 15.5 14.2 14.2 14.5 13.3 13.6 13.3 13.7 17.1 16.5 15.6 19.3 19.1 20.1 – 18.0 17.2
Std Deviation (1e-4) 2.1 2.9 2.0 2.4 2.5 2.6 5.8 3.0 3.1 3.0 4.0 3.2 2.7 3.2 2.4 5.8 5.2 4.9 – 3.5 3.6
Intensity Change (Log2) – – – 0.09 0.07 -0.05 -0.05 -0.02 -0.14 -0.11 -0.14 -0.1 0.22 0.16 0.08 0.4 0.38 0.45 – 0.29 0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020WT1AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 2.5 2.8 0 0 3.9 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.1 -0.8 -1.0 -0.6 -0.4 0.6 0.2 0.2 1.1 -0.2 -1.0 -0.7 0.4 0.2 -0.9
Cytoplasm 1.3 -0.5 -3.1 -7.8 -9.1 -9.6 -9.4 -10.5 -10.4 2.2 1.4 1.8 0.7 2.6 1.2
Endoplasmic Reticulum -1.2 -0.6 1.6 3.3 2.6 4.7 4.9 3.7 5.0 -1.0 -0.8 -0.5 0.2 -2.2 0.4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 3.4 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 3.2 4.2 8.8 8.1 8.2 9.1 11.0 10.0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 4.3 2.9 2.5 3.0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 18.9832 28.6931 25.4217 22.1199 19.6055 24.8214 17.8753 30.5962 25.8965 24.8594 20.2174 26.7831 22.38 30.0386 23.5441 28.6072 25.8603 27.4601
Actin 0.0155 0.0012 0.0139 0.0014 0.0164 0.0036 0.0246 0.0012 0.0062 0.0046 0.0009 0.024 0.0186 0.0005 0.0494 0.0002 0.006 0.0011
Bud 0.0017 0.0006 0.0012 0.0021 0.0008 0.0015 0.001 0.001 0.0006 0.0011 0.0025 0.0005 0.0013 0.001 0.0015 0.0011 0.0005 0.001
Bud Neck 0.0009 0.0006 0.0009 0.0009 0.0008 0.0019 0.0011 0.0003 0.0008 0.0058 0.0007 0.0008 0.0011 0.0003 0.0013 0.0006 0.0006 0.0016
Bud Periphery 0.0022 0.0003 0.0013 0.0007 0.0004 0.0016 0.001 0.0007 0.0002 0.0005 0.0027 0.0002 0.0012 0.0011 0.0015 0.0001 0.0002 0.0008
Bud Site 0.003 0.0005 0.0006 0.0015 0.0005 0.0007 0.0027 0.0014 0.0007 0.0024 0.0005 0.0001 0.0041 0.0002 0.0127 0.0002 0.0007 0.0002
Cell Periphery 0.003 0.0007 0.0008 0.0004 0.0003 0.0008 0.0021 0.0023 0.0002 0.0004 0.0005 0.0001 0.0025 0.0002 0.0013 0.0002 0.0001 0.0003
Cytoplasm 0.6482 0.9168 0.8103 0.6693 0.623 0.7413 0.6353 0.9439 0.8171 0.6511 0.7127 0.8349 0.702 0.9529 0.7283 0.866 0.7992 0.8371
Cytoplasmic Foci 0.024 0.0062 0.0105 0.0185 0.0171 0.0154 0.0465 0.0048 0.0392 0.0236 0.0226 0.0226 0.0083 0.003 0.0279 0.0059 0.0365 0.0108
Eisosomes 0.0002 0 0.0001 0 0.0003 0.0001 0.0003 0 0 0.0001 0 0 0.0002 0 0.0003 0 0 0
Endoplasmic Reticulum 0.0723 0.0301 0.0336 0.0493 0.034 0.0837 0.0381 0.0121 0.0184 0.0049 0.0069 0.0152 0.0746 0.0146 0.0122 0.0056 0.0024 0.065
Endosome 0.0635 0.0159 0.0588 0.1284 0.0935 0.0679 0.0887 0.0073 0.04 0.0636 0.079 0.0593 0.0544 0.008 0.0377 0.0285 0.043 0.0452
Golgi 0.0109 0.0037 0.0092 0.0102 0.0077 0.0176 0.0179 0.0011 0.0167 0.0157 0.0117 0.0088 0.0189 0.0011 0.0081 0.0005 0.0452 0.0034
Lipid Particles 0.0106 0.0001 0.0017 0.0009 0.0106 0.0045 0.0524 0.0005 0.0078 0.0081 0.037 0.0039 0.0049 0.0001 0.0192 0.0001 0.0127 0.0001
Mitochondria 0.0146 0.0014 0.0051 0.0042 0.0156 0.0176 0.0081 0.0063 0.0021 0.0078 0.0568 0.0022 0.014 0.0017 0.0174 0.0002 0.0089 0.0059
None 0.0028 0.0002 0.0008 0.0008 0.0306 0.0009 0.0062 0.0004 0.0012 0.0004 0.0004 0.0005 0.0025 0.0004 0.0022 0.0003 0.0002 0.0005
Nuclear Periphery 0.0215 0.0016 0.0034 0.0068 0.0168 0.0087 0.0074 0.0013 0.0036 0.0065 0.0034 0.0044 0.0211 0.0035 0.0052 0.0104 0.0037 0.0051
Nucleolus 0.0013 0 0.0001 0.0003 0.0016 0.0003 0.0005 0.0001 0.0001 0.0003 0.0002 0 0.0002 0 0.0015 0 0.0001 0
Nucleus 0.0077 0.0009 0.0013 0.0031 0.0056 0.003 0.0029 0.001 0.0015 0.0015 0.0026 0.0014 0.0076 0.0013 0.0029 0.002 0.0013 0.0018
Peroxisomes 0.0052 0.0001 0.0009 0.0003 0.002 0.0061 0.0205 0.0002 0.0079 0.009 0.0122 0.0016 0.004 0 0.0126 0.0001 0.0264 0.0001
Punctate Nuclear 0.0036 0 0.0014 0.0003 0.0112 0.0007 0.0089 0 0.0006 0.0004 0.0019 0.0003 0.0016 0.0001 0.0102 0.0001 0.0003 0.0001
Vacuole 0.0657 0.0165 0.0344 0.0786 0.0778 0.0133 0.0281 0.0121 0.0281 0.1362 0.0337 0.0116 0.0467 0.0079 0.0344 0.0565 0.0079 0.0128
Vacuole Periphery 0.0216 0.0027 0.0096 0.022 0.0332 0.0088 0.0055 0.002 0.0071 0.056 0.011 0.0075 0.0105 0.0022 0.0123 0.0214 0.0041 0.0068

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1464.664 1563.3867 1657.6996 1451.0502 1780.2544 1647.6521 1317.2823 1284.1727 1403.1514 1295.3666
Translational Efficiency 1.2429 1.2052 1.2355 1.4048 1.2345 1.1245 1.3728 1.3694 1.3121 1.4788

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
88 108 1945 1654 2238 1401 112 1351 2326 1509 2057 3005

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1439.40 1654.35 1544.36 1734.58 1238.46 1371.48 1940.84 1831.90 1246.06 1391.73 1565.95 1778.33
Standard Deviation 232.91 264.31 273.93 282.36 187.79 250.41 234.12 312.34 193.53 261.79 286.41 300.14
Intensity Change Log 2 — 0.200797 0.101542 0.269119 — 0.147186 0.648134 0.564793 — 0.176250 0.380161 0.413420

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000308 0.000726 0.000134 0.000319 0.000090 0.000288 0.001209 0.000440 0.000099 0.000319 0.000192 0.000373
Bud Neck 0.000455 0.001146 0.001231 0.000776 0.000142 0.000642 0.004360 0.001032 0.000154 0.000678 0.001402 0.000891
Bud Site 0.036730 0.042988 0.008926 0.017183 0.013414 0.018561 0.042596 0.018560 0.014297 0.020309 0.010759 0.017802
Cell Periphery 0.001920 0.001732 0.000407 0.006854 0.000285 0.000362 0.003964 0.004020 0.000347 0.000460 0.000601 0.005580
Cytoplasm 0.599706 0.679534 0.679907 0.815681 0.758830 0.652392 0.620470 0.801585 0.752809 0.654334 0.676671 0.809343
Cytoplasmic Foci 0.201613 0.123267 0.032630 0.017990 0.123745 0.107727 0.073455 0.028413 0.126691 0.108840 0.034853 0.022676
Eisosomes 0.000004 0.000005 0.000014 0.000003 0.000002 0.000008 0.000007 0.000004 0.000002 0.000007 0.000013 0.000004
Endoplasmic Reticulum 0.013298 0.004505 0.005402 0.001797 0.006824 0.005477 0.011064 0.001442 0.007069 0.005407 0.005710 0.001637
Endosome 0.013797 0.012102 0.009583 0.003284 0.004673 0.014949 0.024742 0.005680 0.005018 0.014745 0.010409 0.004362
Golgi 0.055937 0.048284 0.011139 0.022805 0.019282 0.023948 0.055581 0.029400 0.020668 0.025690 0.013559 0.025770
Lipid Particles 0.003311 0.003220 0.002511 0.010809 0.000423 0.001683 0.010000 0.009379 0.000533 0.001793 0.002919 0.010166
Mitochondria 0.002330 0.007749 0.000397 0.000297 0.000701 0.003374 0.000026 0.000638 0.000763 0.003687 0.000377 0.000450
Mitotic Spindle 0.001927 0.004473 0.003461 0.000962 0.000984 0.002381 0.009503 0.001828 0.001020 0.002531 0.003790 0.001351
None 0.000102 0.000191 0.000514 0.000237 0.000262 0.000524 0.000092 0.000197 0.000256 0.000500 0.000491 0.000219
Nuclear Periphery 0.000032 0.000031 0.000253 0.000048 0.000029 0.000097 0.000158 0.000045 0.000029 0.000092 0.000248 0.000047
Nuclear Periphery Foci 0.002058 0.002674 0.003059 0.002544 0.000477 0.000937 0.011512 0.002705 0.000537 0.001062 0.003519 0.002617
Nucleolus 0.000015 0.000023 0.000164 0.000084 0.000021 0.000530 0.000034 0.000429 0.000021 0.000494 0.000157 0.000239
Nucleus 0.000449 0.001855 0.019584 0.002084 0.000940 0.006253 0.002435 0.002634 0.000921 0.005938 0.018650 0.002331
Peroxisomes 0.000248 0.000326 0.000199 0.000234 0.000093 0.000944 0.000250 0.000409 0.000099 0.000900 0.000202 0.000313
Vacuole 0.021243 0.022246 0.193400 0.070751 0.017400 0.117578 0.103496 0.069116 0.017545 0.110755 0.188505 0.070016
Vacuole Periphery 0.044516 0.042924 0.027086 0.025257 0.051383 0.041347 0.025046 0.022044 0.051123 0.041460 0.026975 0.023812

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.35 2.41 -0.27 2.38 -5.74 -3.31 -5.60 -4.19 -1.43 3.59 -3.87 -4.70 -6.81 -0.76 -3.98
Bud Neck -2.88 -5.59 -3.42 1.46 3.61 -9.59 -6.47 -11.43 -4.53 5.00 -10.23 -11.02 -16.07 -3.58 4.02
Bud Site -0.82 5.66 3.92 4.52 -6.90 -3.86 -5.55 -4.12 -0.16 4.49 -4.50 3.57 -3.67 1.64 -6.99
Cell Periphery 0.36 3.64 -6.53 -7.14 -10.31 -2.39 -5.42 -6.76 -6.62 0.02 -2.58 -4.58 -12.30 -12.01 -11.64
Cytoplasm -1.87 -2.38 -6.61 -4.57 -14.19 10.56 4.66 -4.54 -13.37 -5.93 10.08 8.58 -7.71 -16.43 -15.40
Cytoplasmic Foci 3.31 8.18 8.90 8.78 9.10 3.38 6.74 26.49 19.90 6.66 3.86 26.24 30.88 23.72 7.91
Eisosomes -0.90 -4.94 0.22 1.22 5.23 -5.31 -5.98 -2.80 2.53 2.60 -5.42 -6.14 -4.32 3.42 5.06
Endoplasmic Reticulum 1.49 1.38 2.01 1.74 5.32 1.33 -1.11 6.87 4.86 2.62 1.67 1.50 7.30 5.08 6.12
Endosome 0.59 1.69 4.31 5.00 11.37 -11.00 -6.79 -1.78 8.67 6.34 -11.00 -10.30 1.69 11.46 10.82
Golgi 0.75 6.24 4.56 3.22 -7.43 -2.57 -4.72 -4.89 -2.11 3.34 -2.76 7.03 -3.63 -0.01 -8.67
Lipid Particles 0.07 0.65 -5.05 -6.80 -8.60 -3.67 -8.21 -10.63 -8.48 0.49 -3.88 -10.47 -15.05 -11.73 -10.66
Mitochondria -0.67 0.86 0.91 0.97 0.40 -3.03 11.19 0.30 3.00 -2.27 -2.96 1.62 2.00 3.28 -0.28
Mitotic Spindle -1.66 -1.54 1.03 2.83 4.20 -3.30 -2.64 -1.94 0.92 2.33 -3.69 -4.84 -1.39 2.58 3.98
None -1.25 -2.72 -3.22 -0.61 1.80 -0.95 4.01 1.49 1.19 -6.04 -0.96 -1.58 0.84 1.10 1.89
Nuclear Periphery 0.07 -5.20 -1.44 -2.98 4.95 -4.54 -4.76 -2.99 3.36 4.10 -4.52 -5.58 -3.59 3.27 5.12
Nuclear Periphery Foci -0.70 -1.95 -0.96 0.14 2.10 -3.73 -5.58 -10.70 -7.77 4.37 -4.10 -12.13 -15.47 -9.29 3.31
Nucleolus -1.57 -6.45 -10.00 -8.32 3.32 -2.17 -3.94 -1.17 0.37 -1.13 -2.17 -6.29 -1.40 1.08 -0.53
Nucleus -1.62 -9.82 -10.16 0.27 8.89 -5.43 -4.74 -6.37 3.57 -0.77 -5.54 -9.62 -9.61 3.94 8.74
Peroxisomes -1.05 0.75 0.26 1.54 -0.74 -3.40 -4.82 -3.90 2.09 -1.77 -3.45 -2.56 -5.58 2.52 -1.98
Vacuole -0.24 -23.65 -10.15 -9.76 17.75 -18.19 -5.11 -14.88 7.22 1.89 -18.04 -28.70 -21.64 7.02 18.55
Vacuole Periphery 0.14 2.20 2.40 1.58 0.81 3.08 4.81 10.02 6.78 0.58 3.03 8.94 10.44 6.87 1.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 40S subunit protein S0A; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication;
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Rps0a

Rps0a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rps0a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available