Standard name
Human Ortholog
Description Major karyopherin; involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0 0.08 0.09 0.11 0.07 0.09 0.06 0.09 – 0.1 0.05 0 0.07 0.09 – 0 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0.12 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0.06 0.12 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.06 – 0.07 0.07 0 0 0 – 0 0 0 0 0 0 0 0
Nucleus 0.65 0.75 0.66 0.63 0.53 0.48 0.59 0.62 0.62 – 0.58 0.6 0.45 0.3 0.13 – 0.59 0.06 0.52 0.66 0.44 0.52 0.46 0.21
Nuclear Periphery 0 0 0.06 0.15 0.13 0.1 0.11 0.06 0.08 – 0.06 0.09 0.13 0.15 0.27 – 0 0 0.15 0 0.14 0 0 0
Nucleolus 0.09 0 0.06 0.11 0.19 0.26 0.18 0.14 0.12 – 0.19 0.17 0.14 0.22 0.33 – 0 0.06 0.2 0.14 0.2 0.12 0.07 0.11
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.24 0.28 0.21 0.1 0.12 0.15 0.1 0.13 0.08 – 0.05 0.12 0.38 0.38 0.24 – 0.35 0.69 0.12 0.14 0.17 0.26 0.4 0.56
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 1 0 0 3 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 1 1 0 0 – 0 0 0 0 1 – 0 0 0 2 1 0 1 1
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 3 1 2 – 2 4 0 0 2 – 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 8 4 10 16 22 14 24 19 15 – 17 11 3 12 14 – 0 2 0 0 0 0 0 0
Endoplasmic Reticulum 1 0 0 0 1 2 0 1 1 – 0 0 1 0 2 – 0 2 0 0 0 0 0 0
Endosome 0 1 0 0 0 1 0 0 0 – 0 1 0 3 7 – 0 0 0 0 2 1 0 5
Golgi 1 0 0 0 1 0 1 1 0 – 0 0 0 0 0 – 1 2 0 0 0 0 0 3
Mitochondria 0 0 0 3 1 6 8 13 11 – 12 15 0 0 3 – 0 0 0 0 1 3 0 2
Nucleus 85 145 83 110 107 96 163 190 106 – 99 121 38 49 20 – 10 1 82 152 66 57 65 37
Nuclear Periphery 2 4 8 27 27 20 29 19 14 – 11 19 11 24 42 – 0 0 23 9 20 1 3 5
Nucleolus 12 5 7 19 38 51 49 44 21 – 33 34 12 37 52 – 0 1 31 31 30 13 10 18
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 1 – 0 0 0 0 0 1 0 0
Vac/Vac Membrane 31 54 27 17 25 30 28 41 13 – 9 25 32 63 38 – 6 11 18 33 26 28 57 97
Unique Cell Count 131 193 126 175 201 200 276 307 171 171 201 85 165 158 17 16 159 232 152 111 143 175
Labelled Cell Count 140 213 135 192 222 222 306 329 183 183 231 97 188 185 17 19 159 232 152 111 143 175


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 25.7 21.9 18.6 17.8 20.5 18.5 18.3 15.9 16.9 – 16.0 15.4 20.5 19.5 17.5 – 33.9 30.2 20.0 22.6 25.7
Std Deviation (1e-4) 7.4 5.4 6.7 6.2 9.0 7.2 7.6 6.1 7.4 – 6.7 6.9 5.2 6.1 5.6 – 13.0 10.5 5.5 6.3 6.8
Intensity Change (Log2) – – – -0.07 0.14 -0.01 -0.03 -0.23 -0.14 – -0.22 -0.27 0.14 0.06 -0.09 – 0.86 0.7 0.11 0.28 0.47

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Cytoplasm 0.4 0.9 -0.3 0.3 -0.7 0.3 – 0.6 -0.9 -1.3 -0.2 0.3 – 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Mitochondria 0 0 0 0 0 0 – 3.0 3.1 0 0 0 – 0 0
Nucleus -0.5 -2.3 -3.2 -1.3 -0.8 -0.7 – -1.4 -1.0 -3.0 -6.1 -9.3 – -0.6 -4.6
Nuclear Periphery 2.4 2.0 1.1 1.3 -0.1 0.6 – 0 1.0 1.6 2.2 4.4 – 0 0
Nucleolus 1.6 3.4 4.6 3.3 2.6 2.0 – 3.4 3.0 2.1 4.0 5.6 – 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 – 0 0
Vacuole -2.8 -2.2 -1.5 -3.1 -2.1 -3.4 – -4.2 -2.2 2.6 3.1 0.5 – 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 19.5745 25.3239 22.7358 21.5222 21.2287 22.7062 22.6759 28.2168 23.5842 19.5951 21.9032 24.9246 25.1905 24.8817 23.9287 22.5404 22.4833 23.3519
Actin 0.0673 0.0003 0.0015 0.0217 0.0332 0.0258 0.0106 0.0003 0.007 0.0011 0.003 0.0006 0.0005 0.0009 0.0007 0.0004 0.0003 0.0005
Bud 0.0009 0 0.0005 0.0001 0.0004 0.0002 0.0002 0 0.0004 0.0002 0.0003 0 0.0001 0.0002 0.0057 0 0 0
Bud Neck 0.0038 0.0001 0.0002 0.0002 0.0011 0.0019 0.0002 0.0001 0.0003 0.0002 0.0005 0.0007 0 0.0021 0.0001 0.0001 0.0002 0.0005
Bud Periphery 0.0017 0.0001 0.001 0.0002 0.0009 0.0009 0.0004 0 0.0006 0.0004 0.0005 0.0002 0.0002 0.0011 0.0018 0.0001 0.0001 0.0002
Bud Site 0.0082 0 0.0003 0.0002 0.001 0.0002 0.0005 0 0.0007 0.0006 0.0005 0 0.0001 0.0002 0.0046 0 0 0
Cell Periphery 0.002 0.0001 0.0004 0.0003 0.001 0.0004 0.0003 0.0001 0.0003 0.0004 0.0003 0.0001 0.0001 0.0009 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.0049 0.0005 0.0009 0.0015 0.0005 0.0005 0.0043 0.0003 0.0027 0.002 0.0014 0.0005 0.0002 0.0006 0.0007 0.0011 0.0006 0.0003
Cytoplasmic Foci 0.0297 0 0 0.0181 0.0023 0.0005 0.0118 0 0.0071 0.002 0.0146 0.0045 0.0003 0 0 0 0.0001 0
Eisosomes 0.0007 0 0 0.0001 0.0004 0.0005 0.0001 0 0.0002 0.0001 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0061 0.0002 0.0005 0.0005 0.0003 0.0015 0.0029 0.0001 0.0015 0.0014 0.001 0.0004 0.0002 0.0006 0.0002 0.0003 0.0003 0.0003
Endosome 0.0255 0 0.0003 0.002 0.0014 0.0028 0.0102 0.0002 0.0085 0.0066 0.0108 0.0005 0.0002 0.0003 0.0001 0.0001 0.0004 0.0001
Golgi 0.0122 0 0 0.0019 0.0049 0.0035 0.0036 0.0001 0.0035 0.001 0.0073 0.0001 0 0 0 0 0.0001 0
Lipid Particles 0.0183 0 0.0001 0.0052 0.0146 0.0028 0.0162 0.0008 0.0047 0.0194 0.0181 0.0026 0.0004 0 0 0 0.0016 0
Mitochondria 0.0147 0.0014 0.0047 0.0053 0.0429 0.0066 0.0056 0.0039 0.0164 0.0386 0.0268 0.0015 0.0096 0.0014 0.0016 0.001 0.0024 0.0014
None 0.0037 0 0.0002 0.0018 0.0003 0.0026 0.0029 0 0.0014 0.0007 0.0004 0.0002 0.0001 0 0.0002 0 0.0001 0
Nuclear Periphery 0.325 0.3114 0.3757 0.3247 0.0636 0.2855 0.3769 0.3355 0.4535 0.3113 0.2988 0.3225 0.324 0.3316 0.5473 0.4199 0.2973 0.3309
Nucleolus 0.0125 0.0028 0.0086 0.0128 0.0374 0.0211 0.0129 0.0054 0.0089 0.0088 0.0185 0.005 0.0062 0.0055 0.002 0.0051 0.0106 0.0051
Nucleus 0.4018 0.6744 0.5923 0.5779 0.7721 0.6211 0.5107 0.6383 0.4581 0.5717 0.5774 0.6514 0.6455 0.6224 0.4257 0.5628 0.6739 0.651
Peroxisomes 0.0191 0 0 0.0067 0.0029 0.0006 0.0032 0 0.0013 0.0006 0.0021 0.0001 0 0 0 0 0 0
Punctate Nuclear 0.0081 0.0001 0.0005 0.0028 0.0005 0.0019 0.0089 0.0003 0.0022 0.0029 0.0027 0.0022 0.0034 0.0005 0.0005 0.0004 0.0007 0.0002
Vacuole 0.0111 0.0012 0.0024 0.0015 0.0046 0.0034 0.0049 0.001 0.005 0.0075 0.003 0.0009 0.0009 0.0239 0.0006 0.002 0.0013 0.0011
Vacuole Periphery 0.0226 0.0073 0.0096 0.0144 0.0138 0.0156 0.0126 0.0135 0.0157 0.0225 0.0119 0.0063 0.0079 0.0077 0.008 0.0065 0.0101 0.0082

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 124.4084 98.4861 102.3133 136.9868 110.7571 107.7384 106.3965 113.8421 108.4325 127.5256
Translational Efficiency 1.1861 1.3931 1.2515 0.9176 1.1139 1.122 1.0227 0.8283 0.9502 0.8807

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
381 177 500 93 1487 1758 857 136 1868 1935 1357 229

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1119.70 2061.45 2700.58 3164.34 1525.62 1723.43 2661.30 3066.15 1442.83 1754.35 2675.77 3106.03
Standard Deviation 265.39 419.91 454.52 769.15 316.96 370.91 522.17 641.37 347.98 388.09 498.67 697.76
Intensity Change Log 2 — 0.880547 1.270157 1.498792 — 0.175887 0.802735 1.007033 — 0.516805 1.019297 1.235903

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001387 0.001765 0.002115 0.001690 0.001605 0.001894 0.002206 0.002263 0.001561 0.001882 0.002172 0.002030
Bud Neck 0.004009 0.006213 0.011594 0.036558 0.006154 0.005000 0.009882 0.027614 0.005717 0.005111 0.010513 0.031246
Bud Site 0.000552 0.000206 0.000420 0.003618 0.000789 0.000290 0.000418 0.002447 0.000740 0.000282 0.000419 0.002923
Cell Periphery 0.000113 0.000047 0.000095 0.000315 0.000083 0.000083 0.000086 0.000279 0.000089 0.000080 0.000089 0.000294
Cytoplasm 0.003327 0.000325 0.000317 0.000966 0.000853 0.000764 0.000458 0.000903 0.001357 0.000724 0.000406 0.000928
Cytoplasmic Foci 0.000973 0.000484 0.000956 0.020048 0.000236 0.000558 0.001089 0.003771 0.000386 0.000551 0.001040 0.010381
Eisosomes 0.000028 0.000017 0.000031 0.000042 0.000017 0.000024 0.000025 0.000041 0.000020 0.000023 0.000027 0.000041
Endoplasmic Reticulum 0.004239 0.002709 0.000967 0.001163 0.004549 0.003997 0.001036 0.001111 0.004486 0.003879 0.001010 0.001132
Endosome 0.000693 0.000210 0.000195 0.009119 0.000311 0.000466 0.000285 0.002601 0.000389 0.000442 0.000252 0.005248
Golgi 0.000651 0.000243 0.000741 0.008960 0.000251 0.000553 0.000531 0.001967 0.000333 0.000524 0.000608 0.004807
Lipid Particles 0.000397 0.000111 0.000136 0.001870 0.000076 0.000160 0.000504 0.001241 0.000142 0.000156 0.000368 0.001496
Mitochondria 0.003078 0.005064 0.009004 0.015682 0.004465 0.004380 0.007114 0.012861 0.004182 0.004443 0.007811 0.014007
Mitotic Spindle 0.006510 0.005945 0.020588 0.169051 0.000777 0.003347 0.008822 0.080724 0.001946 0.003585 0.013157 0.116595
None 0.004513 0.000879 0.000687 0.000945 0.001595 0.001518 0.000780 0.001402 0.002190 0.001459 0.000746 0.001216
Nuclear Periphery 0.038645 0.134703 0.194453 0.174088 0.071713 0.074696 0.170475 0.133253 0.064968 0.080185 0.179310 0.149837
Nuclear Periphery Foci 0.100331 0.044358 0.047850 0.100979 0.031182 0.025460 0.047259 0.056459 0.045285 0.027189 0.047477 0.074539
Nucleolus 0.351261 0.374521 0.379371 0.247544 0.287340 0.311575 0.384190 0.358907 0.300378 0.317333 0.382414 0.313681
Nucleus 0.466215 0.410951 0.314866 0.180755 0.572025 0.548854 0.351436 0.278458 0.550444 0.536240 0.337962 0.238780
Peroxisomes 0.002876 0.002313 0.007485 0.013331 0.000869 0.001520 0.005144 0.008959 0.001278 0.001592 0.006007 0.010734
Vacuole 0.003494 0.002145 0.001447 0.006652 0.003409 0.003785 0.001661 0.012960 0.003427 0.003635 0.001582 0.010398
Vacuole Periphery 0.006706 0.006791 0.006683 0.006625 0.011701 0.011077 0.006599 0.011780 0.010682 0.010685 0.006630 0.009686

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.07 -4.78 -2.39 -0.95 0.58 -4.21 -7.65 -3.55 -2.11 -0.62 -4.83 -9.22 -4.12 -2.03 -0.13
Bud Neck -2.39 -8.21 -5.26 -4.98 -4.31 1.39 -5.75 -6.46 -6.63 -5.43 0.57 -8.65 -8.07 -8.14 -6.80
Bud Site 2.52 0.63 -3.12 -3.41 -3.21 0.85 0.26 -3.50 -4.49 -4.13 0.99 0.37 -4.41 -5.55 -5.20
Cell Periphery 3.12 0.66 -4.80 -6.13 -5.24 -0.28 -1.68 -6.07 -5.85 -5.54 0.49 -1.28 -8.00 -7.95 -7.62
Cytoplasm 1.72 1.73 1.29 -4.02 -4.57 0.25 2.47 -1.64 -1.65 -2.92 1.53 2.39 0.31 -2.11 -4.46
Cytoplasmic Foci 1.45 0.11 -3.27 -3.35 -3.28 -1.22 -2.78 -4.00 -3.65 -3.05 -0.64 -3.00 -4.11 -4.04 -3.85
Eisosomes 2.81 -0.80 -2.47 -3.77 -2.23 -3.60 -6.42 -7.47 -5.18 -4.76 -2.12 -6.08 -6.41 -5.32 -4.37
Endoplasmic Reticulum 2.63 6.86 5.23 3.10 -1.12 1.59 14.36 12.31 10.04 -0.94 1.94 16.03 12.62 9.84 -1.44
Endosome 4.47 4.70 -1.51 -1.63 -1.63 -1.56 0.08 -1.58 -1.43 -1.59 -0.59 2.55 -2.01 -1.98 -2.07
Golgi 2.31 -0.53 -1.47 -1.56 -1.45 -1.12 -7.15 -6.16 -3.73 -5.06 -0.78 -6.08 -2.06 -1.95 -1.91
Lipid Particles 3.32 3.12 -2.75 -3.31 -3.25 -1.76 -1.18 -2.38 -2.18 -1.11 -0.36 -0.99 -3.79 -3.71 -2.60
Mitochondria -3.46 -10.73 -2.91 -2.45 -1.53 0.13 -6.46 -5.18 -5.25 -3.43 -0.96 -10.48 -4.85 -4.72 -3.00
Mitotic Spindle 0.28 -2.85 -5.96 -5.99 -5.42 -2.40 -5.14 -4.99 -4.82 -4.37 -1.31 -6.30 -7.77 -7.65 -6.88
None 2.58 2.77 2.39 -1.02 -3.31 0.12 4.83 -0.85 -0.62 -2.83 1.29 4.59 1.45 -0.32 -3.55
Nuclear Periphery -5.54 -12.11 -5.59 -0.77 1.46 -0.45 -10.48 -2.23 -2.06 3.78 -2.99 -14.78 -4.87 -3.63 3.66
Nuclear Periphery Foci 4.34 4.69 0.67 -2.94 -3.04 1.79 -3.69 -2.42 -3.38 -0.10 5.01 -0.29 -2.55 -5.30 -2.47
Nucleolus -0.91 -1.51 3.81 4.04 4.88 -2.58 -8.11 -2.19 -1.19 1.70 -1.95 -8.34 -0.03 0.89 4.25
Nucleus 1.90 7.21 9.92 6.96 4.94 2.09 16.99 9.63 8.80 1.45 1.34 19.53 14.60 13.87 3.89
Peroxisomes 1.36 -8.08 -3.68 -3.85 -2.25 -6.39 -17.28 -9.09 -8.24 -3.66 -2.84 -18.93 -6.82 -6.59 -3.43
Vacuole 1.36 2.05 -2.49 -4.00 -4.54 -0.76 4.59 -1.80 -1.71 -2.16 -0.46 5.13 -2.38 -2.29 -3.02
Vacuole Periphery -0.00 0.08 0.27 0.53 0.45 0.47 4.00 0.66 0.46 -0.84 0.06 3.80 1.17 1.14 -0.72
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Major karyopherin; involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin
Localization
Cell Percentages nucleus (48%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Crm1

Crm1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Crm1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available