Standard name
Human Ortholog
Description Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.25 0.3 0.24 0.24 0.18 0.25 0.11 0.13 0.33 0.16 0.25 0.18 0.22 0.17 0.09 0.17 0.16 0.19 0.2 0.19 0.18 0.2 0.24 0.18
Bud 0.06 0 0.16 0.1 0 0.09 0.08 0.09 0.16 0.13 0.12 0.11 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.24 0.27 0.29 0.26 0 0.05 0.06 0.05 0.12 0.08 0.18 0.08 0.06 0.09 0.11 0.28 0.28 0.25 0.13 0.15 0.13 0 0 0
Endoplasmic Reticulum 0.2 0.26 0.11 0.08 0 0.09 0 0.06 0.06 0 0.08 0 0.09 0.06 0 0 0.06 0 0.14 0.1 0.13 0 0 0.05
Endosome 0 0 0.05 0 0 0 0.08 0.07 0 0 0.07 0.05 0 0 0 0.05 0 0 0.07 0.06 0.14 0.06 0.08 0.06
Golgi 0.36 0.4 0.23 0.25 0.44 0.22 0.16 0.13 0.19 0.11 0.12 0.13 0.7 0.64 0.56 0.51 0.65 0.62 0.39 0.35 0.3 0.6 0.57 0.57
Mitochondria 0.27 0.16 0.42 0.48 0.69 0.79 0.7 0.69 0.58 0.74 0.56 0.74 0.48 0.45 0.45 0.08 0.1 0.08 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.06 0.09 0.05 0 0.07 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0.06 0 0 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 64 88 30 30 33 39 26 38 73 42 41 45 90 79 44 71 37 37 59 67 27 63 80 70
Bud 16 8 20 12 6 15 18 27 36 34 20 27 3 10 6 8 5 5 5 12 1 5 2 9
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 0 0 0 2
Bud Site 0 0 0 0 0 2 1 3 4 2 0 5 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 6 0 1 0 2 0 4 10 7 10 7 5 8 3 8 5 3 1 0 0 0 0 0
Cytoplasm 61 79 36 33 8 8 14 15 27 21 30 20 26 44 52 117 67 49 38 54 19 4 4 8
Endoplasmic Reticulum 51 77 14 10 6 14 8 16 14 11 13 7 37 27 20 15 15 8 42 34 20 13 14 21
Endosome 3 0 6 3 8 6 19 20 8 8 11 12 5 7 14 21 5 2 22 20 22 19 26 23
Golgi 90 117 28 31 82 34 38 37 41 28 19 32 282 300 275 209 154 122 118 124 46 191 193 225
Mitochondria 69 46 52 61 129 125 164 199 126 196 92 182 193 212 222 31 23 16 4 8 5 5 2 12
Nucleus 0 1 0 0 1 0 1 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 1
Nuclear Periphery 0 0 0 0 1 3 1 2 0 2 3 0 1 1 1 1 1 0 0 0 0 0 0 1
Nucleolus 4 0 4 4 4 9 22 15 3 19 1 12 5 7 16 6 6 4 0 0 0 0 0 0
Peroxisomes 0 0 0 0 5 2 2 5 3 2 0 2 2 2 5 1 0 0 1 1 1 2 5 5
SpindlePole 0 0 0 1 0 1 2 6 3 3 1 4 1 1 0 9 4 0 1 3 0 3 2 0
Vac/Vac Membrane 0 4 2 2 6 2 11 16 4 1 4 5 7 10 14 24 6 6 1 16 5 5 2 8
Unique Cell Count 251 291 124 126 188 158 234 290 219 265 165 247 404 470 488 413 238 197 304 355 155 317 341 395
Labelled Cell Count 363 426 192 188 289 262 327 403 352 376 245 361 657 708 672 523 328 252 304 355 155 317 341 395


Late Golgi, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 19.1 20.7 13.1 10.9 12.9 11.7 10.0 10.1 11.0 10.1 9.9 10.3 20.5 19.8 19.3 18.4 22.9 23.4 18.7 18.0 19.0
Std Deviation (1e-4) 3.5 4.2 2.3 3.1 2.5 2.5 2.4 2.2 2.1 2.0 2.0 1.9 4.0 4.5 5.3 5.0 6.5 6.4 3.9 3.8 3.9
Intensity Change (Log2) – – – -0.27 -0.03 -0.17 -0.39 -0.38 -0.26 -0.38 -0.41 -0.36 0.64 0.59 0.55 0.48 0.8 0.83 0.51 0.45 0.54


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.1 -1.4 0.1 -3.2 -2.8 1.8 -2.0 0.1 -1.4 -0.4 -1.9 -4.6 -1.7 -2.0 -1.2
Bud -1.6 -4.0 -1.7 -2.5 -2.0 0.1 -0.9 -1.0 -1.4 -7.3 -6.3 -7.3 -6.2 -5.0 -4.4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 -6.2 -5.5 -6.0 -6.8 -3.8 -5.5 -2.2 -5.3 -6.8 -5.7 -5.2 -0.2 -0.2 -0.8
Endoplasmic Reticulum -0.9 -2.9 -0.7 -3.0 -2.1 -1.6 -2.7 -1.0 -3.3 -0.7 -2.2 -3.1 -3.3 -1.7 -2.5
Endosome 0 -0.2 -0.4 1.2 0.8 -0.5 0 0.7 0 0 0 0 0.1 0 0
Golgi 0.4 3.8 -0.2 -1.5 -2.5 -0.9 -3.1 -2.5 -2.4 9.3 8.2 6.7 5.5 7.6 6.9
Mitochondria 1.0 4.7 6.4 5.2 5.1 2.8 6.1 2.3 6.0 1.1 0.6 0.7 -9.3 -7.2 -7.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 1.0 2.1 0.9 0 1.5 0 0.7 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 1.8 0 0 0 0 0 0 0 1.9 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 18.7112 20.953 21.3864 21.4725 20.5385 22.0043 12.5473 17.8306 16.7065 16.0336 16.6629 15.4505 16.843 18.092 19.7 18.0106 17.3675 18.1645
Actin 0.1264 0.0442 0.0585 0.0329 0.0391 0.042 0.1751 0.1725 0.1409 0.0813 0.0996 0.0989 0.2382 0.1358 0.0772 0.0172 0.0134 0.115
Bud 0.0012 0.0033 0.0084 0.0048 0.0014 0.0002 0.0045 0.0015 0.0108 0.0021 0.0004 0.0003 0.0072 0.0042 0.02 0.0018 0.0124 0.0007
Bud Neck 0.0045 0.0013 0.0023 0.0022 0.0026 0.0027 0.004 0.0006 0.0016 0.0012 0.0007 0.0011 0.002 0.0009 0.0012 0.0009 0.0011 0.0011
Bud Periphery 0.0015 0.0019 0.0053 0.0052 0.0024 0.0002 0.005 0.0006 0.0094 0.0007 0.0003 0.0003 0.0023 0.0015 0.0122 0.0009 0.0156 0.0007
Bud Site 0.0027 0.0169 0.01 0.0023 0.0016 0.0002 0.0084 0.0018 0.0041 0.0016 0.0004 0.0002 0.0444 0.0054 0.0036 0.0004 0.061 0.0006
Cell Periphery 0.001 0.001 0.0008 0.0011 0.0006 0.0002 0.0005 0.0007 0.0008 0.0002 0.0001 0.0001 0.0004 0.0002 0.0006 0.0007 0.0018 0.0001
Cytoplasm 0.0303 0.0389 0.0891 0.1113 0.0319 0.0036 0.0172 0.0208 0.0614 0.0743 0.0385 0.0038 0.0282 0.0563 0.0814 0.2953 0.1007 0.0047
Cytoplasmic Foci 0.0726 0.1304 0.0803 0.1002 0.1027 0.0374 0.0683 0.0546 0.0869 0.1108 0.081 0.0326 0.0706 0.1338 0.0993 0.1092 0.0649 0.0345
Eisosomes 0.0006 0.0003 0.0001 0.0001 0.0002 0.0001 0.001 0.0001 0.0004 0 0 0.0002 0.0003 0.0001 0.0003 0 0.0001 0.0002
Endoplasmic Reticulum 0.008 0.0015 0.003 0.0045 0.0081 0.0011 0.0049 0.0004 0.0074 0.002 0.0059 0.0021 0.0021 0.0013 0.0021 0.006 0.002 0.0007
Endosome 0.1905 0.2421 0.2792 0.3305 0.3153 0.1352 0.1597 0.158 0.1991 0.3403 0.221 0.0931 0.1244 0.2368 0.1921 0.2088 0.2023 0.0874
Golgi 0.4406 0.4309 0.3898 0.3292 0.4341 0.7505 0.4122 0.5523 0.4338 0.3492 0.5329 0.7274 0.453 0.402 0.4804 0.2673 0.5102 0.7069
Lipid Particles 0.0404 0.0279 0.0238 0.0243 0.0222 0.0085 0.0413 0.0017 0.0165 0.016 0.0052 0.0134 0.0058 0.007 0.0053 0.0714 0.0007 0.0043
Mitochondria 0.029 0.0148 0.0162 0.0068 0.0195 0.0121 0.0253 0.019 0.006 0.0035 0.0026 0.0086 0.0036 0.0061 0.0103 0.0015 0.0051 0.0385
None 0.0097 0.0003 0.0009 0.0003 0.0003 0 0.0288 0.0001 0.001 0.0001 0.0001 0.0009 0.0005 0.0001 0.0002 0.0002 0.0007 0.0001
Nuclear Periphery 0.007 0.001 0.0018 0.001 0.0026 0.0001 0.0026 0.0001 0.0016 0.0005 0.0008 0.0059 0.0003 0.0003 0.0006 0.0023 0.0006 0.0001
Nucleolus 0.0012 0.0007 0.001 0.0002 0.0001 0 0.0035 0.0001 0.0001 0 0 0.0002 0.0001 0 0.0001 0.0001 0.0001 0.0001
Nucleus 0.0024 0.0009 0.0012 0.0005 0.0005 0 0.0033 0.0002 0.0004 0.0001 0.0001 0.0005 0.0003 0.0001 0.0003 0.0012 0.0009 0.0001
Peroxisomes 0.0092 0.0047 0.0043 0.0019 0.0034 0.0013 0.0095 0.0037 0.0062 0.008 0.001 0.005 0.0139 0.0034 0.0029 0.0009 0.0015 0.0021
Punctate Nuclear 0.0045 0.0025 0.0016 0.0006 0.0006 0.0001 0.0158 0.0001 0.0008 0.0002 0.0001 0.0034 0.0006 0.0002 0.0003 0.0003 0.0003 0.0002
Vacuole 0.0119 0.024 0.0158 0.0324 0.0063 0.0017 0.006 0.0087 0.0062 0.0047 0.0065 0.0006 0.001 0.0025 0.0062 0.0103 0.003 0.0007
Vacuole Periphery 0.0048 0.0106 0.0067 0.0076 0.0044 0.0026 0.0031 0.0025 0.0046 0.0031 0.0027 0.0013 0.0008 0.0016 0.0034 0.0033 0.0016 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 87.2256 59.1306 64.6107 70.0383 73.5097 74.8272 62.9076 76.2699 63.5376 71.9949
Translational Efficiency 1.0698 1.2551 1.0707 1.0382 0.9657 0.9824 0.8974 0.7355 0.9924 0.9365

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
113 1491 108 433 206 884 287 161 319 2375 395 594

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1534.36 1521.35 2330.02 2020.32 1555.67 1611.63 2238.69 2239.01 1548.12 1554.95 2263.66 2079.59
Standard Deviation 230.75 341.94 294.39 344.87 243.82 293.97 263.18 315.11 239.49 327.83 275.10 350.80
Intensity Change Log 2 — -0.012285 0.602705 0.396947 — 0.050985 0.525119 0.525325 — 0.019915 0.564166 0.463006

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.032022 0.038016 0.054495 0.020144 0.013361 0.018219 0.029876 0.012646 0.019971 0.030648 0.036607 0.018111
Bud Neck 0.003342 0.002268 0.020792 0.004831 0.002925 0.002005 0.012294 0.006333 0.003073 0.002170 0.014618 0.005238
Bud Site 0.043106 0.028530 0.038406 0.061088 0.045329 0.029914 0.090078 0.071447 0.044542 0.029045 0.075950 0.063896
Cell Periphery 0.001705 0.001213 0.021288 0.016459 0.007443 0.000882 0.016795 0.037085 0.005410 0.001090 0.018024 0.022050
Cytoplasm 0.006434 0.011494 0.001853 0.052713 0.009691 0.014268 0.027056 0.061638 0.008537 0.012527 0.020165 0.055132
Cytoplasmic Foci 0.161531 0.105320 0.026157 0.058122 0.128089 0.155134 0.061479 0.050045 0.139936 0.123861 0.051822 0.055932
Eisosomes 0.000235 0.000242 0.000745 0.000260 0.000131 0.000104 0.000214 0.000143 0.000168 0.000191 0.000359 0.000228
Endoplasmic Reticulum 0.013508 0.005163 0.027826 0.004787 0.010506 0.003954 0.011815 0.005683 0.011570 0.004713 0.016192 0.005030
Endosome 0.149419 0.134301 0.091856 0.092686 0.097771 0.127262 0.087390 0.071326 0.116067 0.131681 0.088611 0.086896
Golgi 0.520877* 0.593000* 0.376040* 0.455830* 0.638121* 0.571831* 0.433856* 0.427642* 0.596589* 0.585121* 0.418048* 0.448189*
Lipid Particles 0.031861 0.042437 0.158361* 0.102289* 0.017072 0.022102 0.120578* 0.120771* 0.022311 0.034868 0.130909* 0.107299*
Mitochondria 0.004857 0.010666 0.004058 0.000960 0.001467 0.006046 0.001720 0.000525 0.002668 0.008946 0.002360 0.000842
Mitotic Spindle 0.002109 0.003156 0.008022 0.006797 0.001082 0.014082 0.009599 0.002675 0.001446 0.007223 0.009168 0.005680
None 0.000055 0.000152 0.000172 0.000129 0.000062 0.000066 0.000106 0.000114 0.000060 0.000120 0.000124 0.000125
Nuclear Periphery 0.000068 0.000090 0.001675 0.000576 0.000051 0.000130 0.000347 0.000203 0.000057 0.000105 0.000710 0.000475
Nuclear Periphery Foci 0.000910 0.001250 0.009370 0.004621 0.001177 0.001757 0.004870 0.004488 0.001082 0.001438 0.006100 0.004585
Nucleolus 0.000008 0.000469 0.000085 0.000029 0.000009 0.000026 0.000020 0.000032 0.000009 0.000304 0.000038 0.000030
Nucleus 0.000064 0.000186 0.000309 0.000455 0.000064 0.000081 0.000399 0.000709 0.000064 0.000147 0.000374 0.000524
Peroxisomes 0.002809 0.002534 0.000474 0.001161 0.000732 0.002244 0.001136 0.001815 0.001468 0.002426 0.000955 0.001338
Vacuole 0.016764 0.011742 0.137596 0.098353 0.015143 0.019547 0.078298 0.104392 0.015717 0.014647 0.094511 0.099990
Vacuole Periphery 0.008315 0.007772 0.020420 0.017714 0.009772 0.010346 0.012073 0.020287 0.009256 0.008730 0.014355 0.018411

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.73 -1.40 1.43 3.90 2.36 -1.10 -2.64 0.13 1.46 2.93 -2.54 -2.59 0.39 3.71 3.11
Bud Neck 1.83 -5.86 -2.16 -4.28 5.28 0.90 -5.60 -3.09 -5.45 3.37 1.32 -7.99 -3.06 -6.39 6.57
Bud Site 1.37 0.09 -1.94 -6.16 -2.31 1.88 -4.35 -2.45 -4.34 1.31 2.42 -3.92 -3.11 -7.53 1.30
Cell Periphery 1.51 -3.85 -6.21 -6.45 0.93 2.86 -2.80 -3.58 -4.61 -2.40 2.90 -4.71 -5.26 -7.62 -1.01
Cytoplasm -2.14 2.08 -7.14 -6.57 -7.92 -1.48 -3.32 -5.20 -4.82 -3.14 -2.00 -3.11 -8.56 -8.07 -5.37
Cytoplasmic Foci 3.35 7.97 6.01 9.04 -5.65 -2.62 6.30 6.94 13.11 1.37 1.83 9.50 9.15 15.17 -0.79
Eisosomes -0.16 -1.72 -0.15 -0.09 1.60 1.34 -2.61 -0.25 -1.33 2.07 -1.04 -2.23 -0.70 -0.41 1.23
Endoplasmic Reticulum 2.23 -2.20 2.35 0.48 4.35 3.21 -0.37 2.19 -1.11 2.66 3.64 -1.59 3.47 -0.20 5.17
Endosome 1.12 3.74 4.18 7.24 0.03 -3.81 1.49 2.88 6.88 1.98 -2.25 3.82 4.06 9.52 0.45
Golgi -2.54 3.84 2.65 8.67 -2.02 3.24 8.17 6.77 5.42 0.47 0.73 8.49 7.92 10.10 -0.94
Lipid Particles -1.47 -5.93 -6.51 -6.56 2.42 -1.21 -9.18 -6.35 -6.10 0.08 -3.29 -10.72 -10.21 -9.11 1.81
Mitochondria -1.82 0.24 1.33 7.57 1.41 -2.72 -0.14 1.36 3.52 0.88 -4.21 0.23 1.61 8.12 1.32
Mitotic Spindle -1.23 -1.69 -3.36 -2.87 0.42 -5.89 -3.05 -3.43 4.99 2.48 -6.27 -3.45 -4.26 0.49 1.44
None -4.07 -2.87 -3.18 0.82 0.97 -0.29 -2.63 -2.50 -2.69 -0.41 -4.02 -3.91 -4.05 -0.56 -0.08
Nuclear Periphery -1.44 -5.13 -1.80 -1.72 2.63 -4.61 -3.83 -4.65 -2.21 1.61 -4.74 -6.14 -2.05 -1.81 1.04
Nuclear Periphery Foci -1.40 -6.56 -6.41 -5.99 3.25 -1.59 -6.75 -4.99 -3.84 0.17 -1.68 -9.37 -7.61 -6.86 1.94
Nucleolus -1.15 -1.56 -5.24 1.09 1.09 -1.30 -2.73 -3.55 -0.85 -2.40 -1.17 -2.12 -5.63 1.08 0.35
Nucleus -1.12 -2.55 -5.55 -2.82 -1.22 -0.91 -3.68 -1.97 -1.94 -1.29 -1.22 -4.36 -3.76 -3.17 -1.48
Peroxisomes 0.33 3.13 2.20 3.45 -3.32 -3.90 -2.19 -1.70 0.42 -1.13 -2.50 1.71 0.31 3.08 -1.59
Vacuole 1.11 -6.96 -10.11 -12.41 1.96 -1.38 -8.48 -7.87 -7.57 -2.29 0.35 -10.78 -13.44 -14.38 -0.97
Vacuole Periphery 0.18 -2.26 -2.75 -5.90 0.62 -0.28 -0.92 -1.90 -1.88 -1.56 0.31 -2.22 -3.68 -5.16 -1.65
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
Localization
Cell Percentages cytoplasm (17%), Golgi (6%), mixed (42%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Smi1

Smi1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Smi1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available