Standard name
Human Ortholog
Description High affinity nicotinic acid plasma membrane permease; responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – 0.06 0.1 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 – 0 0 0 0 0 0 – 0 0.06 0 0 0 0 – – – 0 0 0 0.05 0.08 0.09
Bud Neck 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 – 0 0.05 0.05 0 0 0 – 0 0 0 0 0.05 0.07 – – – 0 0 0 0 0 0
Cytoplasm 0.26 – 0.09 0.23 0.35 0.63 0.79 0.8 – 0.76 0.67 0.66 0.68 0.64 0.63 – – – 0.09 0.07 0 0.27 0.28 0.32
Endoplasmic Reticulum 0.62 – 0.74 0.58 0.47 0.19 0 0 – 0 0 0 0.26 0.33 0.26 – – – 0.8 0.83 0.88 0.47 0.44 0.35
Endosome 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 – 0 0.07 0 0.13 0.11 0.19 – 0.36 0.48 0.47 0 0 0 – – – 0 0 0 0.1 0.06 0.06
Nucleus 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 – 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0.15 – 0.16 0.12 0.18 0.1 0.09 0 – 0 0 0.05 0.06 0 0.08 – – – 0 0 0 0 0.05 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – 16 20 13 2 1 1 – 0 0 0 1 2 6 – – – 2 0 6 5 21 15
Bud 0 – 1 2 3 7 12 11 – 10 22 19 2 1 0 – – – 2 0 4 14 39 45
Bud Neck 0 – 0 0 0 0 2 0 – 2 4 2 1 4 5 – – – 0 1 1 6 5 12
Bud Site 0 – 0 0 0 0 0 0 – 1 0 1 0 0 1 – – – – – – – – –
Cell Periphery 0 – 11 11 18 2 5 2 – 2 4 2 4 14 23 – – – 0 0 2 2 8 9
Cytoplasm 9 – 24 47 117 205 404 579 – 408 239 351 108 190 210 – – – 9 2 3 80 138 168
Endoplasmic Reticulum 21 – 196 118 156 62 17 13 – 6 3 9 41 97 87 – – – 80 33 261 142 217 184
Endosome 0 – 3 6 12 8 16 11 – 2 0 1 0 0 0 – – – 0 0 1 1 1 1
Golgi 0 – 11 3 0 0 1 0 – 0 0 0 1 0 0 – – – 0 0 1 0 1 1
Mitochondria 0 – 8 14 10 41 56 134 – 192 171 248 1 0 0 – – – 0 0 3 29 28 30
Nucleus 0 – 0 1 0 0 1 8 – 1 3 3 0 2 2 – – – 0 0 0 0 0 0
Nuclear Periphery 0 – 4 3 3 6 1 2 – 0 1 8 0 1 0 – – – 1 0 5 2 0 1
Nucleolus 0 – 0 0 0 0 0 4 – 0 0 1 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 – 1 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 1 2 2 – 5 5 12 0 1 6 – – – 0 0 0 1 5 9
Vac/Vac Membrane 5 – 43 25 61 31 46 27 – 21 11 27 10 12 28 – – – 1 1 3 10 22 35
Unique Cell Count 34 265 202 334 325 509 721 537 359 533 159 298 332 101 40 298 301 496 521
Labelled Cell Count 35 317 250 393 365 564 794 651 463 684 169 324 368 101 40 298 301 496 521


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.4 – 12.7 12.3 8.7 5.4 4.2 4.1 – 3.2 3.3 3.1 7.0 7.9 8.7 3.1 3.6 3.9 7.8 7.9 7.4
Std Deviation (1e-4) 3.7 – 4.8 5.7 3.0 1.7 1.5 1.3 – 1.2 1.3 1.0 2.5 3.1 4.4 0.7 1.0 0.9 3.5 2.6 2.6
Intensity Change (Log2) – – – -0.04 -0.54 -1.25 -1.58 -1.63 – -1.99 -1.93 -2.04 -0.87 -0.7 -0.55 -2.03 -1.8 -1.72 -0.7 -0.69 -0.78

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.6 -1.2 -3.8 0 0 – 0 0 0 -2.7 -3.6 -2.7 – – –
Bud 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Cell Periphery 0.7 0.7 -2.9 0 0 – 0 0 0 -0.9 0.3 1.5 – – –
Cytoplasm 4.2 7.4 13.4 18.7 20.3 – 17.9 14.4 15.1 12.7 13.3 13.5 – – –
Endoplasmic Reticulum -3.5 -6.7 -13.4 0 0 – 0 0 0 -9.7 -9.8 -11.6 – – –
Endosome 0 1.9 0 0 0 – 0 0 0 0 0 0 – – –
Golgi -1.7 0 0 0 0 – 0 0 0 0 -3.6 0 – – –
Mitochondria 2.0 0 4.2 0 0 – 0 0 0 0 0 0 – – –
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 – – –
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 – – –
Vacuole -1.2 0.7 -2.4 -3.0 -6.8 – -6.1 -5.8 -5.2 -3.0 -4.9 -2.9 – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0006 0.0017 0.0033 0.0003 0.0012 0.0016 0.0175 0.0007 0.007 0.007 0.002 0.0003 0.0001 0.0002 0.0328 0.0001 0.0104 0.0026
Bud 0.0006 0.0148 0.0117 0 0.0001 0.001 0.0012 0.0005 0.0037 0.0002 0 0 0 0 0.0009 0 0.0002 0.0001
Bud Neck 0.0003 0.0008 0.0007 0.0007 0.006 0.0023 0.0093 0.0003 0.0005 0.0025 0.0008 0.0004 0 0 0.0013 0 0.001 0.0004
Bud Periphery 0.0044 0.007 0.007 0 0.0001 0.0041 0.0029 0.0009 0.0072 0.0005 0 0 0 0 0.0031 0 0.0003 0.0004
Bud Site 0.0009 0.0343 0.0029 0.0002 0.0001 0.0002 0.0042 0.0085 0.003 0.0003 0.0001 0 0 0.0002 0.0142 0 0.0024 0
Cell Periphery 0.0066 0.0069 0.0018 0.0004 0.0009 0.0025 0.0016 0.0127 0.0031 0.0011 0.0003 0.0004 0.0002 0.0006 0.0008 0.0002 0.0004 0.0004
Cytoplasm 0.0789 0.2058 0.095 0.1346 0.3685 0.136 0.0482 0.1024 0.1019 0.0633 0.1775 0.122 0.0206 0.1474 0.1573 0.1082 0.57 0.1672
Cytoplasmic Foci 0.0147 0.0084 0.0061 0.0057 0.0077 0.0088 0.0445 0.002 0.0185 0.0204 0.0112 0.0077 0.0028 0.0032 0.0084 0.002 0.0523 0.0038
Eisosomes 0.0001 0.0002 0.0001 0 0 0.0003 0.0003 0 0.0001 0.0006 0 0.0001 0 0.0001 0.0005 0 0.0002 0
Endoplasmic Reticulum 0.6979 0.5333 0.6524 0.8039 0.5515 0.7113 0.6469 0.7717 0.702 0.6717 0.6887 0.7625 0.8835 0.5523 0.4614 0.5638 0.0775 0.6163
Endosome 0.0138 0.0062 0.0103 0.0114 0.0146 0.0098 0.0421 0.0034 0.007 0.0365 0.0094 0.0089 0.0231 0.0101 0.0096 0.0028 0.0143 0.0058
Golgi 0.0005 0.0004 0.0011 0.0005 0.0013 0.0007 0.0178 0.0003 0.0018 0.0095 0.0078 0.0005 0.0006 0.0003 0.0012 0.0002 0.023 0.0004
Lipid Particles 0.0038 0.0032 0.0069 0.0017 0.0023 0.0046 0.0191 0.0096 0.0096 0.034 0.0246 0.009 0.017 0.0027 0.0056 0.0006 0.033 0.0014
Mitochondria 0.0011 0.0008 0.0019 0.0001 0.0008 0.0006 0.0069 0.0002 0.0013 0.0022 0.0005 0.0001 0 0.0001 0.0033 0.0001 0.043 0.0002
None 0.1147 0.1006 0.1172 0.0166 0.0085 0.0663 0.0753 0.0507 0.0955 0.1205 0.0517 0.0769 0.0011 0.2703 0.2533 0.3148 0.0085 0.1847
Nuclear Periphery 0.0279 0.0352 0.0347 0.0152 0.0225 0.0289 0.0203 0.0195 0.014 0.0107 0.0058 0.0068 0.043 0.007 0.0144 0.0047 0.0017 0.011
Nucleolus 0.0006 0.0024 0.0014 0.0001 0.0001 0.0002 0.001 0.0002 0.0006 0.0003 0 0 0 0 0.0012 0 0.0002 0
Nucleus 0.0125 0.0155 0.021 0.002 0.0034 0.0121 0.0028 0.0035 0.0037 0.0017 0.0015 0.0008 0.0011 0.001 0.0249 0.0005 0.0015 0.0014
Peroxisomes 0.0001 0.0002 0.0002 0 0.0001 0.0001 0.0057 0.0001 0.007 0.0048 0.0153 0.0001 0 0 0.0005 0 0.1575 0
Punctate Nuclear 0.0064 0.0071 0.0093 0.0007 0.0006 0.0017 0.0189 0.0013 0.0046 0.0018 0.0007 0.0004 0.0006 0.0004 0.002 0.0002 0.0006 0.0003
Vacuole 0.0122 0.0143 0.0125 0.0053 0.0086 0.0057 0.0106 0.0109 0.0061 0.009 0.0018 0.0028 0.0054 0.0037 0.0028 0.0013 0.0018 0.0031
Vacuole Periphery 0.0013 0.0011 0.0024 0.0005 0.0012 0.0012 0.0028 0.0007 0.0016 0.0015 0.0002 0.0002 0.0007 0.0003 0.0006 0.0002 0.0003 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 51.2172 51.0089 55.6361 56.0817 37.4366 47.4098 53.7499 41.9393 51.5556 49.0864
Translational Efficiency 0.9609 0.9725 0.7708 0.8145 1.0323 1.1324 1.0562 1.0785 0.8939 0.7962

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
48 205 116 914 414 1493 385 1032 462 1698 501 1946

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1602.76 930.39 10831.61 4689.76 2710.11 775.41 5899.15 4412.80 2595.06 794.12 7041.20 4542.88
Standard Deviation 556.85 291.67 2936.03 1754.57 880.66 168.63 2074.08 1509.86 917.26 194.49 3103.31 1635.23
Intensity Change Log 2 — -0.784651 2.756617 1.548956 — -1.805320 1.122156 0.703343 — -1.338200 1.955783 1.077624

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.004907 0.000821 0.000416 0.003282 0.002744 0.000788 0.001750 0.003321 0.002968 0.000792 0.001441 0.003303
Bud Neck 0.005948 0.010367 0.037890 0.010929 0.002046 0.017308 0.007890 0.006457 0.002452 0.016470 0.014836 0.008557
Bud Site 0.024544 0.014802 0.002507 0.019370 0.002456 0.020796 0.015985 0.013021 0.004751 0.020072 0.012864 0.016003
Cell Periphery 0.017254 0.001513 0.099255 0.062816 0.009246 0.002543 0.033314 0.065999 0.010078 0.002418 0.048581 0.064504
Cytoplasm 0.065320 0.222019 0.000105 0.009008 0.000187 0.315347 0.001390 0.005164 0.006954 0.304079 0.001093 0.006969
Cytoplasmic Foci 0.050538 0.088818 0.000125 0.003179 0.000333 0.114395 0.002855 0.001565 0.005549 0.111307 0.002223 0.002323
Eisosomes 0.000281 0.000195 0.013142 0.000790 0.001061 0.000288 0.000954 0.000734 0.000980 0.000277 0.003776 0.000760
Endoplasmic Reticulum 0.339619 0.481312 0.473140 0.654033 0.942196 0.305158 0.815997 0.697966 0.879591 0.326425 0.736613 0.677332
Endosome 0.039063 0.018146 0.009182 0.016103 0.006776 0.022361 0.007830 0.013780 0.010131 0.021853 0.008143 0.014871
Golgi 0.011118 0.004528 0.013529 0.015014 0.006274 0.005897 0.014247 0.017012 0.006778 0.005731 0.014081 0.016074
Lipid Particles 0.042150 0.024355 0.064473 0.084795 0.004610 0.036156 0.028575 0.077283 0.008510 0.034731 0.036887 0.080811
Mitochondria 0.000124 0.004842 0.001800 0.005083 0.001824 0.009105 0.002190 0.003087 0.001648 0.008590 0.002100 0.004024
Mitotic Spindle 0.004343 0.001063 0.000715 0.003497 0.000228 0.001029 0.000341 0.002883 0.000655 0.001033 0.000428 0.003171
None 0.000054 0.001295 0.000064 0.001443 0.000231 0.007033 0.000403 0.001857 0.000212 0.006341 0.000325 0.001663
Nuclear Periphery 0.000931 0.006462 0.075925 0.012031 0.005013 0.006276 0.012367 0.009647 0.004589 0.006299 0.027083 0.010767
Nuclear Periphery Foci 0.019948 0.016215 0.016741 0.022198 0.004146 0.009551 0.006460 0.016468 0.005788 0.010356 0.008840 0.019159
Nucleolus 0.000076 0.000456 0.000124 0.000117 0.000044 0.000989 0.000049 0.000072 0.000047 0.000925 0.000066 0.000093
Nucleus 0.003255 0.045528 0.000499 0.001664 0.000120 0.059915 0.000520 0.001206 0.000445 0.058178 0.000515 0.001421
Peroxisomes 0.002818 0.003926 0.000007 0.000820 0.000092 0.006459 0.000289 0.000210 0.000376 0.006153 0.000223 0.000497
Vacuole 0.359320 0.050761 0.176518 0.065815 0.006789 0.056115 0.040036 0.054411 0.043415 0.055469 0.071637 0.059767
Vacuole Periphery 0.008386 0.002575 0.013844 0.008012 0.003584 0.002490 0.006558 0.007859 0.004083 0.002501 0.008245 0.007931

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.36 1.52 0.32 -2.81 -3.42 0.99 0.22 -0.45 -3.04 -1.26 1.19 0.58 -0.41 -4.24 -2.24
Bud Neck -1.29 -4.33 -3.66 -0.95 3.45 -9.08 -4.20 -5.36 5.35 1.24 -9.15 -6.04 -7.98 3.64 2.79
Bud Site 1.28 3.73 0.25 -1.42 -7.24 -7.62 -4.08 -6.25 1.72 0.93 -6.54 -3.26 -7.37 0.23 -0.94
Cell Periphery 1.83 -6.33 -5.53 -16.51 3.17 4.02 -6.00 -13.43 -16.13 -5.72 4.43 -9.02 -17.26 -22.74 -3.15
Cytoplasm -5.56 3.91 3.30 10.94 -5.90 -40.71 -3.09 -5.20 39.16 -3.85 -39.24 2.89 -0.57 40.30 -6.48
Cytoplasmic Foci -2.71 5.09 4.76 7.99 -4.24 -25.18 -1.88 -3.65 24.83 0.91 -24.20 1.85 2.32 25.88 -0.05
Eisosomes 0.74 -5.19 -3.77 -4.99 4.97 1.46 0.20 0.63 -4.32 1.32 1.48 -3.50 0.48 -6.07 4.79
Endoplasmic Reticulum -2.56 -2.24 -5.51 -4.76 -4.79 51.29 8.51 19.87 -25.24 5.99 34.87 7.91 14.66 -26.09 3.42
Endosome 2.24 3.36 2.52 0.67 -4.63 -9.47 -1.07 -5.58 4.96 -4.29 -6.61 1.05 -3.48 4.54 -6.18
Golgi 0.86 -0.50 -0.70 -5.53 -0.79 0.32 -4.32 -6.14 -8.30 -1.55 0.72 -4.35 -5.96 -10.33 -1.45
Lipid Particles 1.00 -1.43 -2.70 -8.82 -1.32 -12.33 -5.16 -14.29 -7.68 -6.80 -8.98 -6.06 -17.35 -11.21 -7.09
Mitochondria -1.71 -1.60 -3.56 -0.23 -2.03 -5.94 -0.66 -1.31 5.00 -0.60 -6.10 -0.76 -2.42 3.61 -1.79
Mitotic Spindle 0.97 1.00 0.81 -2.28 -3.46 -2.68 -1.14 -2.67 -1.82 -2.51 0.48 0.86 -0.84 -3.04 -4.13
None -3.90 0.15 -4.40 -0.54 -4.50 -9.24 -1.51 -2.26 4.78 -1.94 -9.42 -1.27 -3.54 5.87 -3.13
Nuclear Periphery -3.36 -10.60 -13.34 -3.24 9.03 -0.90 -4.06 -4.19 -3.85 1.59 -1.41 -9.04 -6.30 -5.64 6.88
Nuclear Periphery Foci 0.56 0.10 -0.72 -1.85 -1.05 -3.47 -1.57 -5.83 -3.87 -4.32 -2.92 -2.14 -7.31 -5.71 -4.96
Nucleolus -3.04 -0.11 -0.37 3.19 -0.30 -5.29 -0.70 -1.37 5.15 -0.91 -5.52 -1.01 -2.26 5.22 -1.47
Nucleus -6.60 1.61 0.74 7.44 -4.66 -23.57 -2.80 -4.88 22.56 -2.36 -24.50 -0.79 -4.60 23.72 -4.18
Peroxisomes -0.54 1.87 1.28 1.97 -1.49 -9.91 -1.17 -1.08 9.72 0.54 -9.34 0.72 -0.33 8.78 -0.91
Vacuole 7.11 4.11 6.70 -2.49 6.22 -17.13 -6.75 -14.27 -0.34 -1.74 -1.58 -3.44 -2.75 -2.39 1.70
Vacuole Periphery 1.08 -1.15 -0.07 -3.64 2.19 1.32 -2.36 -3.34 -5.43 -0.83 1.69 -3.28 -3.46 -7.37 0.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description High affinity nicotinic acid plasma membrane permease; responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)
Localization
Cell Percentages ER (98%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Tna1

Tna1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tna1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available