Standard name
Human Ortholog
Description Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.09 0 0.09 0.05 0.06 0.1 0.14 0.15 0.15 0.17 0.18 0.08 0.13 0.43 0.18 0.11 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0.05 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.17 0.09 0.08 0 0.08 0.11 0.06 0 0.05 0.05 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.28 0.21 0.31 0.31 0.3 0.35 0.33 0.33 0.29 0.25 0.22 0.2 0.25 0.32 0.18 0.43 0.42 0.46 0.08 0.08 0 0.06 0.07 0.06
Nuclear Periphery 0.11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.63 0.64 0.65 0.76 0.76 0.64 0.65 0.68 0.69 0.69 0.73 0.75 0.7 0.65 0.54 0.42 0.5 0.49 0.79 0.79 0.87 0.82 0.82 0.82
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0
Bud 1 0 0 0 0 0 2 0 2 1 2 0 0 0 0 0 0 0 0 2 3 4 3 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 1 0 0 0 3 0 0 0 0 0 0 0 0 0
Cytoplasm 4 14 12 27 14 23 61 92 65 71 79 100 23 50 163 30 27 18 0 1 1 2 0 4
Endoplasmic Reticulum 0 1 1 2 0 0 1 0 0 1 2 3 1 0 0 3 3 4 0 0 0 2 0 0
Endosome 1 0 8 4 7 0 1 1 0 0 1 0 20 34 21 3 5 0 4 3 5 6 10 12
Golgi 0 0 0 0 1 0 0 1 0 0 0 0 3 0 0 1 2 3 1 0 2 0 0 1
Mitochondria 38 13 24 1 23 44 38 19 23 25 22 34 8 5 2 7 10 7 5 2 4 4 5 2
Nucleus 61 31 89 91 91 137 210 222 129 117 102 109 77 123 68 74 100 97 18 12 10 17 22 19
Nuclear Periphery 23 3 12 3 7 5 6 8 2 1 2 2 5 2 1 1 0 1 7 3 6 1 5 7
Nucleolus 9 15 8 5 5 8 3 4 1 2 1 1 3 3 0 6 7 11 9 6 3 5 4 5
Peroxisomes 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 1 1 0 1 0 0 4 2 3 1 0 2 0 0 0 0 1 0
Vac/Vac Membrane 137 96 190 225 233 248 407 455 305 324 343 417 212 252 207 72 121 104 181 130 271 222 259 268
Unique Cell Count 219 149 291 295 305 386 630 672 439 468 473 556 305 386 382 171 240 213 230 165 313 270 317 327
Labelled Cell Count 274 173 344 359 382 466 730 804 527 543 557 666 357 472 468 198 275 247 230 165 313 270 317 327


Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.3 15.1 11.8 13.4 15.3 13.9 15.1 17.2 16.9 16.5 16.4 15.9 9.9 7.6 6.4 14.2 14.2 15.2 13.2 12.3 13.1
Std Deviation (1e-4) 3.7 7.0 4.1 3.7 6.5 6.6 7.2 8.8 8.9 9.2 9.1 8.7 3.0 2.0 1.7 7.1 6.1 7.3 5.5 4.4 4.0
Intensity Change (Log2) – – – 0.18 0.37 0.24 0.36 0.55 0.52 0.48 0.47 0.43 -0.25 -0.63 -0.87 0.27 0.27 0.37 0.16 0.06 0.15

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70001020WT3HU80HU120HU16001020WT3rpd3Δ_1rpd3Δ_2rpd3Δ_301020WT1AF100AF140AF18001020
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.4 0.3 1.1 2.9 4.4 4.6 4.7 5.2 5.7 1.8 3.9 11.3 4.8 3.1 2.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -1.2 -0.4 0 0 0 0 0 0 0 2.2 3.2 1.7 0 -0.5 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -4.7 -0.3 1.4 -1.2 -3.7 -1.6 -1.6 -2.0 -1.2 -3.0 -4.4 -5.2 -1.7 -1.9 -2.3
Nucleus 0.1 -0.2 1.3 0.8 0.7 -0.3 -1.7 -2.8 -3.6 -1.5 0.4 -3.9 2.8 2.7 3.4
Nuclear Periphery -2.4 -1.3 -2.3 -3.2 -2.9 -3.5 0 -3.7 0 -1.8 -3.3 -3.6 0 -3.2 -2.6
Nucleolus -0.9 -0.9 -0.6 0 0 0 0 0 0 -1.6 0 0 0.5 0.1 1.4
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.9 3.0 -0.3 -0.2 0.7 1.2 1.1 2.1 3.0 1.1 0 -2.9 -4.9 -3.5 -3.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.415 9.7354 8.1569 6.7717 8.3991 8.9013 4.9574 9.8048 8.3241 7.8968 8.3992 9.704 3.2455 8.1491 6.4839 4.808 6.1353 8.881
Actin 0.0049 0 0.0069 0 0 0.0004 0.0004 0.0003 0.0042 0 0.0397 0 0.0124 0.0019 0.0017 0.0819 0.035 0
Bud 0.0005 0.0002 0.0003 0.0038 0.0007 0.0004 0.0003 0.0002 0.0002 0.0001 0.0004 0.0002 0.0003 0.0002 0.0004 0.0011 0.0012 0.0002
Bud Neck 0.0014 0.0007 0.0007 0.0019 0.002 0.001 0.0007 0.0007 0.0005 0.0004 0.0011 0.0008 0.0005 0.0007 0.0007 0.0009 0.0019 0.0008
Bud Periphery 0.0015 0.0008 0.0011 0.0148 0.0026 0.0017 0.001 0.0006 0.0009 0.0005 0.0007 0.0009 0.0008 0.0007 0.0011 0.0024 0.0015 0.0009
Bud Site 0.0014 0.0003 0.0005 0.0034 0.0014 0.0006 0.0013 0.0014 0.0004 0.0002 0.001 0.0003 0.0009 0.0004 0.0005 0.0019 0.0203 0.0004
Cell Periphery 0.0074 0.0096 0.0081 0.0068 0.0117 0.0155 0.0067 0.0108 0.0093 0.0073 0.0046 0.0102 0.0047 0.0098 0.0059 0.0048 0.008 0.0093
Cytoplasm 0.0016 0.0004 0.0003 0.0005 0.0004 0.0004 0.0009 0.0008 0.0003 0.0002 0.002 0.0003 0.0004 0.0003 0.0006 0.0012 0.0008 0.0003
Cytoplasmic Foci 0.0039 0.0007 0.0021 0.0022 0.0011 0.0007 0.0135 0.0006 0.0021 0.0015 0.0235 0.0026 0.0218 0.0017 0.0032 0.012 0.0122 0.0004
Eisosomes 0.0002 0 0.0001 0 0 0 0 0 0 0 0.0001 0 0.0003 0 0 0.0008 0.0002 0
Endoplasmic Reticulum 0.0029 0.0012 0.001 0.0004 0.0006 0.0008 0.0013 0.0006 0.0007 0.0002 0.0033 0.0006 0.0015 0.0008 0.0015 0.0065 0.0009 0.0006
Endosome 0.0616 0.0292 0.0278 0.0603 0.0488 0.0287 0.0513 0.0167 0.0376 0.0326 0.0581 0.018 0.0542 0.0316 0.0377 0.0943 0.0683 0.014
Golgi 0.0052 0.0013 0.0037 0.0027 0.0077 0.0039 0.0062 0.0008 0.0048 0.0032 0.0115 0.0007 0.0093 0.0035 0.0054 0.067 0.0088 0.0009
Lipid Particles 0.0248 0.0045 0.023 0.0177 0.0182 0.0194 0.0448 0.0054 0.0188 0.0207 0.0413 0.0087 0.0662 0.0145 0.0246 0.0944 0.0866 0.0153
Mitochondria 0.031 0.0071 0.0783 0.0033 0.0149 0.0289 0.0418 0.0016 0.027 0.0057 0.008 0.0028 0.0598 0.0214 0.0653 0.0147 0.0296 0.0025
None 0.0023 0 0.0002 0 0.0001 0.0001 0.0008 0 0.0001 0 0.0012 0.0001 0.0005 0.0001 0.0002 0.004 0.0007 0
Nuclear Periphery 0.0186 0.0031 0.002 0.0009 0.0015 0.0019 0.0038 0.0025 0.0056 0.0005 0.0208 0.0012 0.004 0.0053 0.0051 0.0825 0.0019 0.0015
Nucleolus 0.0124 0.0044 0.011 0.0049 0.0109 0.0106 0.0222 0.0099 0.0167 0.0042 0.0071 0.0071 0.0065 0.0086 0.0102 0.004 0.0159 0.0132
Nucleus 0.01 0.0024 0.0027 0.0049 0.0041 0.0051 0.0072 0.0033 0.0054 0.0017 0.0067 0.0066 0.0021 0.0042 0.0068 0.0039 0.0035 0.0042
Peroxisomes 0.0032 0.0003 0.0024 0.001 0.0011 0.0006 0.0037 0.0002 0.0018 0.0022 0.0054 0.0004 0.0161 0.0048 0.0026 0.0115 0.0085 0.0003
Punctate Nuclear 0.0019 0 0.0001 0 0 0 0.0022 0.0001 0.0001 0 0.0043 0.0032 0.001 0 0.0003 0.0231 0.0009 0
Vacuole 0.4476 0.5596 0.4856 0.5643 0.6145 0.5648 0.4374 0.5947 0.5008 0.6711 0.5176 0.6026 0.3702 0.4815 0.412 0.142 0.4574 0.5811
Vacuole Periphery 0.3556 0.374 0.3421 0.306 0.2576 0.3142 0.3523 0.3489 0.3626 0.2477 0.2418 0.3326 0.3665 0.4078 0.414 0.3451 0.2359 0.3541

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 488.5012 506.3568 796.8684 480.8416 300.0466 547.1224 636.7497 653.9936 585.9135 343.1831
Translational Efficiency 1.8945 2.2467 1.8183 2.0015 2.1983 1.9215 2.0074 2.31 1.7563 1.8512

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1270 316 115 1468 1339 1812 1246 1125 2609 2128 1361 2593

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1279.08 1403.97 1216.60 1108.74 1191.81 1213.35 1109.21 1045.01 1234.29 1241.66 1118.28 1081.09
Standard Deviation 278.15 384.03 156.37 231.17 292.53 236.86 177.65 200.39 288.93 272.52 178.47 220.62
Intensity Change Log 2 — 0.134406 -0.072252 -0.206185 — 0.025842 -0.103622 -0.189638 — 0.083060 -0.087298 -0.198180

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000035 0.000275 0.000169 0.001233 0.000050 0.000053 0.000090 0.002240 0.000043 0.000086 0.000097 0.001670
Bud Neck 0.002162 0.003979 0.038350 0.016203 0.002333 0.003540 0.017534 0.018972 0.002249 0.003605 0.019293 0.017404
Bud Site 0.001919 0.004222 0.019958 0.057708 0.003567 0.003163 0.016853 0.080693 0.002765 0.003320 0.017116 0.067680
Cell Periphery 0.007606 0.007383 0.000881 0.002919 0.010372 0.007069 0.000620 0.003282 0.009026 0.007116 0.000642 0.003077
Cytoplasm 0.000542 0.000570 0.003326 0.062926 0.001844 0.000736 0.005076 0.099987 0.001210 0.000712 0.004928 0.079005
Cytoplasmic Foci 0.000646 0.001043 0.014200 0.056541 0.002021 0.001396 0.022325 0.074216 0.001352 0.001343 0.021639 0.064210
Eisosomes 0.000196 0.000496 0.000063 0.000031 0.000250 0.000708 0.000034 0.000100 0.000224 0.000676 0.000036 0.000061
Endoplasmic Reticulum 0.001778 0.001611 0.001672 0.015836 0.002440 0.002547 0.003045 0.013952 0.002118 0.002408 0.002929 0.015018
Endosome 0.009334 0.009044 0.194037 0.208085 0.010996 0.008178 0.262848 0.200041 0.010187 0.008306 0.257034 0.204595
Golgi 0.001807 0.001763 0.006411 0.030007 0.001752 0.001066 0.010336 0.021844 0.001779 0.001169 0.010005 0.026465
Lipid Particles 0.000705 0.000730 0.002125 0.007436 0.000849 0.000997 0.003092 0.010089 0.000779 0.000957 0.003010 0.008587
Mitochondria 0.010479 0.009484 0.001054 0.002574 0.006695 0.004777 0.002295 0.001910 0.008537 0.005476 0.002190 0.002286
Mitotic Spindle 0.000031 0.000059 0.003092 0.013732 0.000095 0.000103 0.011090 0.008953 0.000063 0.000097 0.010414 0.011658
None 0.000198 0.000287 0.000045 0.000090 0.000192 0.000136 0.000516 0.000087 0.000195 0.000159 0.000476 0.000089
Nuclear Periphery 0.000360 0.000530 0.002006 0.000903 0.000308 0.000637 0.002080 0.000213 0.000333 0.000621 0.002074 0.000604
Nuclear Periphery Foci 0.000550 0.000750 0.006109 0.002873 0.000715 0.000917 0.011957 0.002533 0.000635 0.000893 0.011463 0.002725
Nucleolus 0.001862 0.006483 0.021360 0.000617 0.001393 0.004296 0.008358 0.000561 0.001621 0.004621 0.009457 0.000593
Nucleus 0.001381 0.004421 0.010780 0.002513 0.001264 0.004057 0.008918 0.004473 0.001321 0.004111 0.009076 0.003363
Peroxisomes 0.000538 0.000882 0.013217 0.006681 0.000482 0.000462 0.005988 0.011338 0.000510 0.000524 0.006599 0.008702
Vacuole 0.811248 0.848151 0.588933 0.484170 0.841563 0.892950 0.537691 0.430855 0.826806 0.886298 0.542021 0.461039
Vacuole Periphery 0.146625 0.097834 0.072212 0.026924 0.110818 0.062212 0.069252 0.013659 0.128248 0.067502 0.069502 0.021169

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.19 -4.08 -4.97 -3.00 -4.35 -0.13 -2.82 -5.76 -5.76 -5.63 -1.35 -4.81 -7.59 -7.31 -7.28
Bud Neck -2.26 -3.85 -12.28 -9.20 2.33 -2.24 -11.15 -11.55 -10.74 -0.28 -3.30 -11.71 -16.78 -14.77 1.40
Bud Site -1.56 -4.77 -18.57 -15.96 -7.29 0.41 -9.37 -17.07 -17.13 -13.34 -1.05 -11.18 -24.92 -24.32 -17.01
Cell Periphery 0.13 7.96 5.80 3.17 -3.21 2.61 8.71 6.14 5.33 -3.89 2.16 11.99 8.43 7.02 -5.68
Cytoplasm -0.14 -2.31 -19.89 -19.91 -18.54 1.10 -4.24 -20.61 -20.90 -19.55 0.62 -5.50 -28.47 -28.66 -26.15
Cytoplasmic Foci -0.85 -4.22 -21.70 -21.21 -9.33 0.49 -11.95 -19.65 -20.06 -12.98 -0.20 -13.93 -28.82 -28.53 -15.86
Eisosomes -1.73 7.24 10.20 2.69 3.18 -4.22 3.90 2.63 6.43 -3.09 -5.12 6.34 5.33 7.36 -2.59
Endoplasmic Reticulum 0.52 0.25 -6.01 -6.04 -6.00 -0.35 -1.40 -4.56 -4.53 -4.21 -1.42 -2.16 -7.50 -7.29 -6.71
Endosome 0.14 -9.50 -28.55 -27.64 0.74 1.76 -33.43 -22.30 -23.06 8.90 1.69 -35.09 -36.02 -36.74 9.64
Golgi 0.05 -4.95 -11.30 -10.87 -8.46 1.55 -10.76 -9.33 -9.77 -4.21 1.67 -11.59 -14.56 -14.95 -7.96
Lipid Particles -0.20 -3.35 -7.45 -7.35 -5.35 -1.01 -3.77 -6.76 -6.66 -4.48 -1.84 -4.13 -9.99 -9.75 -5.62
Mitochondria 0.28 5.56 4.78 2.28 -1.89 1.32 3.40 3.59 3.25 0.91 2.38 5.94 5.93 4.00 0.37
Mitotic Spindle -1.49 -2.29 -8.46 -8.45 -5.82 -0.18 -5.94 -5.60 -5.59 0.80 -0.91 -6.08 -10.13 -10.10 -1.28
None -0.89 8.66 -0.54 0.22 -1.94 1.68 -1.52 1.75 0.36 1.78 1.42 -1.46 -0.11 -0.66 1.39
Nuclear Periphery -0.88 -2.17 -1.97 -1.36 1.19 -2.05 -6.37 -0.02 2.18 6.50 -2.07 -6.66 -1.98 -0.46 4.32
Nuclear Periphery Foci -1.09 -5.03 -5.78 -4.97 2.55 -0.63 -6.50 -6.37 -5.15 5.28 -1.10 -6.85 -8.00 -6.04 5.32
Nucleolus -2.15 -3.01 2.97 2.70 3.18 -5.50 -7.53 3.09 7.17 8.42 -5.36 -7.73 4.20 7.41 8.75
Nucleus -1.35 -3.27 -6.17 -0.92 1.51 -3.72 -6.59 -7.73 -3.97 0.51 -3.77 -7.02 -9.98 -3.77 1.74
Peroxisomes -0.87 -3.84 -8.48 -6.99 2.19 0.18 -8.08 -8.38 -8.45 -3.20 -0.08 -8.97 -11.74 -11.75 -1.35
Vacuole -2.87 8.84 31.32 25.22 3.60 -7.64 30.58 36.05 43.41 7.12 -10.79 32.13 47.62 56.76 6.70
Vacuole Periphery 4.86 7.34 23.06 8.69 5.43 9.45 8.37 22.20 18.07 20.09 14.12 14.13 31.42 18.03 18.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication
Localization
Cell Percentages vacuole (57%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Scw4

Scw4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Scw4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available