ORF
Human Ortholog
Description Putative protein of unknown function; transcriptionally regulated by Upc2p via an upstream sterol response element; SWAT-GFP fusion protein localizes to the cell periphery, while mCherry fusion localizes to both the cell periphery and vacuole; YHL026C is not an essential gene; in 2005 the start site was moved 141 nt upstream (see Locus History)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.07 0.1 0.05 0.06 0.06
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.07 0.05 0 0 0 0 – 0 0 0 0.06 0.06 0 0.25 0.3 0.34 0 0.08 0.13 0.22 0.16 0.15
Cytoplasm 1.0 0.97 0.96 0.95 0.97 0.92 0.91 0.84 – 0.84 0.62 0.81 1.0 0.99 1.0 0.77 0.78 0.79 0.56 0.65 0.51 0.46 0.52 0.54
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0.12 0.08 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0 0 0.05 0 0.16 0.2 0.23 – 0.22 0.5 0.37 0 0 0 0.08 0 0 0.17 0.05 0.12 0.14 0.11 0.1
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 1 0 0 0 0 – 1 2 0 0 1 0 5 6 3 1 13 14 14 20 21
Bud 0 0 2 1 2 5 9 8 – 15 15 20 0 1 0 5 3 3 0 1 0 1 7 5
Bud Neck 0 1 2 1 7 9 5 8 – 10 3 7 5 1 4 4 1 0 0 6 3 13 13 13
Bud Site 0 0 0 0 0 2 0 0 – 1 0 3 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 6 10 7 7 10 10 8 – 16 10 12 32 27 24 45 54 49 0 14 18 62 53 57
Cytoplasm 17 165 132 126 311 316 512 445 – 514 230 472 506 465 610 141 140 114 21 122 74 132 174 199
Endoplasmic Reticulum 0 2 0 0 0 0 0 1 – 2 5 1 2 4 2 10 21 11 0 3 6 2 5 6
Endosome 0 1 0 0 0 0 0 0 – 0 0 0 0 0 0 2 1 2 2 1 3 1 3 6
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 1 1 0 0 0 2 1 2
Mitochondria 1 3 3 7 13 54 112 122 – 135 185 217 0 1 0 14 7 3 6 9 16 38 38 37
Nucleus 0 0 1 1 0 0 3 0 – 1 0 2 2 0 0 0 0 0 0 0 0 1 0 0
Nuclear Periphery 0 0 0 0 0 0 1 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 2 4 7 5 – 15 2 12 0 0 0 11 3 0 0 0 0 0 2 1
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 1 0 0 0 1 0 1 0 0 7 0 8 8 14
Unique Cell Count 17 170 137 132 319 343 562 531 615 373 586 508 471 612 182 180 145 38 187 145 286 336 371
Labelled Cell Count 18 178 151 145 342 400 659 598 710 454 746 547 500 641 238 238 186 38 187 145 286 336 371


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.5 4.5 3.2 3.2 3.0 3.0 2.6 2.9 – 2.7 2.4 2.5 5.2 4.9 5.1 5.7 6.0 6.0 5.4 5.5 5.6
Std Deviation (1e-4) 1.8 1.2 0.6 1.4 0.8 1.2 0.8 1.0 – 0.5 0.3 0.6 0.8 0.7 0.8 0.9 1.5 1.2 1.1 1.0 1.1
Intensity Change (Log2) – – – 0.01 -0.09 -0.08 -0.3 -0.14 – -0.22 -0.37 -0.32 0.72 0.64 0.7 0.84 0.92 0.93 0.77 0.79 0.83

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.5039 -0.158 -0.3924 -0.4134 -0.3731 -0.1584 1.472 1.5782 1.5787 1.3591 1.3165 1.5818 -1.4399 -0.7744 -0.9808 -0.6365 -0.9845 -1.0664
Actin 0.0082 0.0011 0.0034 0.0007 0.0151 0.0068 0.0508 0.0024 0.0159 0.0005 0.0224 0.0047 0.0139 0.0006 0.0019 0.0004 0.0072 0.0028
Bud 0.0002 0.0076 0.0027 0.0001 0.0002 0.0007 0.0026 0.0046 0.0013 0.0003 0.0076 0.0008 0.0002 0.0012 0.0013 0.0003 0.0018 0.0014
Bud Neck 0.0005 0.0021 0.0057 0.0012 0.0019 0.0066 0.0061 0.0012 0.0087 0.0007 0.0092 0.0026 0.0046 0.0008 0.0023 0.0005 0.0068 0.008
Bud Periphery 0.0008 0.0024 0.0048 0.0009 0.001 0.0021 0.0093 0.0066 0.0064 0.0005 0.0276 0.004 0.0004 0.0008 0.0012 0.0008 0.0028 0.0019
Bud Site 0.0014 0.019 0.0166 0.0003 0.0006 0.0006 0.0093 0.052 0.0192 0.0008 0.0266 0.0037 0.0014 0.0251 0.0141 0.0009 0.0082 0.0016
Cell Periphery 0.0041 0.01 0.0079 0.0016 0.0063 0.0028 0.0059 0.0087 0.0124 0.0027 0.0046 0.0047 0.0033 0.0085 0.0099 0.0034 0.0012 0.0045
Cytoplasm 0.0798 0.173 0.102 0.0803 0.1701 0.1629 0.1142 0.1726 0.1168 0.1142 0.0686 0.1881 0.1224 0.2279 0.1921 0.1193 0.1112 0.2204
Cytoplasmic Foci 0.0094 0.0037 0.0054 0.025 0.0035 0.0077 0.0108 0.008 0.0074 0.0033 0.004 0.0043 0.0199 0.0107 0.0071 0.011 0.0237 0.0196
Eisosomes 0.002 0.0011 0.0009 0.0003 0.0007 0.0005 0.0016 0.0009 0.0013 0.0008 0.0013 0.0004 0.0014 0.0006 0.0007 0.0003 0.0003 0.0003
Endoplasmic Reticulum 0.0014 0.0017 0.0012 0.0008 0.0012 0.0013 0.0068 0.0021 0.0016 0.0027 0.0023 0.0014 0.0033 0.0017 0.0019 0.0017 0.0015 0.0009
Endosome 0.0042 0.0008 0.0005 0.0007 0.002 0.0013 0.0066 0.001 0.0011 0.0004 0.0027 0.0008 0.0045 0.0004 0.0016 0.0009 0.0096 0.0005
Golgi 0.0015 0.0003 0.0003 0.0002 0.0014 0.0003 0.0034 0.0005 0.0008 0.0001 0.001 0.0005 0.0015 0.0002 0.0005 0.0002 0.0018 0.0001
Lipid Particles 0.0024 0.0006 0.0004 0.0002 0.0009 0.0007 0.0042 0.0017 0.0014 0.0007 0.0015 0.0007 0.008 0.0006 0.0009 0.001 0.0052 0.0006
Mitochondria 0.0019 0.0007 0.0007 0.0001 0.0004 0.0005 0.002 0.0007 0.0007 0.0003 0.0014 0.0004 0.0017 0.0003 0.0004 0.0004 0.0008 0.0002
None 0.8701 0.7691 0.8432 0.8862 0.7872 0.7987 0.7495 0.7302 0.7921 0.8596 0.8053 0.7795 0.7976 0.7147 0.748 0.8516 0.7715 0.7314
Nuclear Periphery 0.0023 0.0004 0.0003 0.0001 0.0036 0.0013 0.0051 0.0004 0.0006 0.0003 0.0033 0.0004 0.0016 0.0002 0.0011 0.0006 0.0067 0.0002
Nucleolus 0.0004 0.0008 0.0005 0.0001 0.0003 0.0003 0.0014 0.0008 0.0012 0.0018 0.0014 0.0003 0.0007 0.0006 0.0009 0.0006 0.0014 0.0004
Nucleus 0.001 0.0021 0.0009 0.0002 0.0006 0.0017 0.0034 0.0014 0.0011 0.0017 0.0025 0.0005 0.0014 0.0007 0.0082 0.0011 0.002 0.0009
Peroxisomes 0.0045 0.0002 0.0007 0.0003 0.0004 0.0007 0.0024 0.0012 0.0056 0.0001 0.0009 0.0005 0.0082 0.0001 0.0002 0.0002 0.0062 0.0002
Punctate Nuclear 0.003 0.0023 0.0008 0.0003 0.0021 0.0016 0.0025 0.0016 0.0026 0.0073 0.0043 0.001 0.003 0.0035 0.0046 0.0038 0.0286 0.0035
Vacuole 0.0006 0.0007 0.0009 0.0002 0.0004 0.0007 0.0016 0.0011 0.0012 0.0008 0.0014 0.0008 0.0009 0.0007 0.001 0.001 0.001 0.0007
Vacuole Periphery 0.0003 0.0001 0.0001 0 0.0002 0.0002 0.0006 0.0001 0.0001 0.0001 0.0003 0.0001 0.0002 0 0.0001 0.0001 0.0003 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.8196 3.1214 14.6696 21.0183 6.0363 12.7961 5.5232 16.3311 15.1962 7.4875
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1574 1776 1243 1622 1466 1419 3096 1765 3040 3195 4339 3387

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 655.26 703.47 867.14 896.48 649.35 648.45 825.12 917.41 652.41 679.03 837.16 907.39
Standard Deviation 67.68 90.53 100.38 123.33 87.28 81.22 105.18 126.69 77.81 90.74 105.55 125.53
Intensity Change Log 2 — 0.102421 0.404197 0.452204 — -0.002001 0.345608 0.498570 — 0.051391 0.375333 0.475468

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000250 0.001214 0.001519 0.043618 0.000550 0.001760 0.011596 0.037509 0.000394 0.001457 0.008709 0.040435
Bud Neck 0.026805 0.051646 0.007779 0.041279 0.028953 0.085282 0.048667 0.046339 0.027841 0.066585 0.036954 0.043916
Bud Site 0.004966 0.025749 0.021924 0.139453 0.011279 0.025830 0.052615 0.141327 0.008011 0.025785 0.043823 0.140430
Cell Periphery 0.000383 0.000537 0.002787 0.076325 0.000362 0.000665 0.020989 0.094721 0.000373 0.000594 0.015775 0.085912
Cytoplasm 0.488196 0.415466 0.500535 0.348879 0.460971 0.300022 0.465020 0.388700 0.475067 0.364194 0.475194 0.369630
Cytoplasmic Foci 0.229103 0.268863 0.065655 0.015754 0.255999 0.322089 0.012341 0.013810 0.242073 0.292503 0.027614 0.014741
Eisosomes 0.000931 0.000911 0.000598 0.039928 0.000838 0.001682 0.009666 0.040497 0.000886 0.001253 0.007068 0.040225
Endoplasmic Reticulum 0.000683 0.001125 0.008425 0.009745 0.001212 0.000858 0.004755 0.005114 0.000938 0.001007 0.005806 0.007332
Endosome 0.008873 0.015134 0.004139 0.001249 0.016134 0.033072 0.000756 0.002129 0.012375 0.023101 0.001725 0.001708
Golgi 0.005623 0.009693 0.000305 0.001696 0.008014 0.023078 0.000410 0.001757 0.006776 0.015638 0.000380 0.001728
Lipid Particles 0.011201 0.009217 0.005432 0.002469 0.015001 0.019317 0.001587 0.001855 0.013034 0.013702 0.002688 0.002149
Mitochondria 0.004124 0.013122 0.000206 0.000745 0.007844 0.036839 0.001020 0.002756 0.005918 0.023655 0.000787 0.001793
Mitotic Spindle 0.001739 0.002841 0.000425 0.002814 0.001230 0.002304 0.000818 0.004354 0.001493 0.002602 0.000706 0.003616
None 0.004117 0.003014 0.003098 0.000778 0.006442 0.001972 0.001092 0.000621 0.005238 0.002551 0.001667 0.000696
Nuclear Periphery 0.000226 0.000182 0.000668 0.000123 0.000225 0.000186 0.000172 0.000105 0.000225 0.000184 0.000314 0.000113
Nuclear Periphery Foci 0.000246 0.000274 0.004317 0.001013 0.000436 0.000450 0.000355 0.000587 0.000338 0.000352 0.001490 0.000791
Nucleolus 0.000804 0.000829 0.000323 0.000050 0.001482 0.000922 0.000094 0.000066 0.001131 0.000871 0.000159 0.000059
Nucleus 0.170970 0.114476 0.273675 0.131847 0.127668 0.054205 0.301541 0.117505 0.150088 0.087708 0.293558 0.124373
Peroxisomes 0.006461 0.019390 0.000441 0.001065 0.009188 0.042812 0.000830 0.002069 0.007776 0.029793 0.000719 0.001588
Vacuole 0.033704 0.045042 0.097632 0.140899 0.044880 0.043775 0.065440 0.097463 0.039094 0.044479 0.074662 0.118264
Vacuole Periphery 0.000595 0.001274 0.000118 0.000272 0.001291 0.002879 0.000233 0.000716 0.000931 0.001987 0.000200 0.000503

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.73 -5.34 -19.26 -18.75 -18.56 -6.00 -13.41 -18.40 -17.73 -11.95 -8.13 -14.01 -26.63 -25.82 -19.48
Bud Neck -7.79 8.76 -4.57 4.13 -15.49 -13.09 -7.28 -6.49 9.38 0.99 -14.82 -4.35 -7.85 9.50 -3.25
Bud Site -10.70 -7.81 -25.10 -19.95 -20.42 -7.00 -15.70 -24.35 -21.05 -15.56 -12.41 -18.75 -34.98 -28.95 -23.17
Cell Periphery -2.35 -7.15 -20.56 -20.51 -19.81 -4.51 -17.85 -23.31 -23.23 -17.49 -4.70 -18.33 -30.98 -30.90 -24.16
Cytoplasm 8.54 0.61 17.31 8.31 14.55 17.24 -0.10 8.35 -9.74 10.04 17.35 1.31 17.89 -0.36 17.78
Cytoplasmic Foci -5.58 30.29 43.63 47.33 17.91 -8.18 45.81 45.31 50.44 -1.20 -9.38 58.33 62.80 68.60 10.98
Eisosomes 0.18 3.27 -18.59 -18.60 -18.77 -5.07 -16.94 -20.93 -20.41 -15.71 -3.72 -16.31 -27.96 -27.65 -22.69
Endoplasmic Reticulum -1.62 -10.50 -15.37 -13.40 -0.95 1.43 -8.79 -10.70 -12.04 -0.48 -0.38 -14.03 -18.76 -17.29 -2.74
Endosome -5.19 5.37 9.09 15.75 9.19 -7.48 12.97 11.31 15.87 -3.24 -8.72 14.74 14.34 21.15 0.38
Golgi -4.46 8.79 4.97 9.34 -2.29 -8.56 10.24 6.96 12.77 -2.44 -9.41 13.42 8.45 15.69 -3.29
Lipid Particles 1.88 4.58 9.72 11.44 3.21 -2.48 10.80 10.69 13.60 -1.20 -0.71 12.86 14.43 17.40 1.71
Mitochondria -6.90 8.17 6.73 10.20 -2.77 -10.00 7.36 4.43 12.04 -2.29 -11.83 10.00 6.58 15.04 -2.44
Mitotic Spindle -0.99 1.77 -0.76 0.14 -2.32 -1.16 0.73 -2.41 -1.39 -2.96 -1.51 1.63 -2.26 -0.92 -3.63
None 1.99 1.76 6.28 4.90 3.70 3.80 5.10 5.56 2.81 3.28 4.24 6.23 7.99 5.67 4.33
Nuclear Periphery 1.26 -11.23 2.69 1.73 16.77 1.28 1.83 5.60 3.64 6.05 1.79 -5.16 5.38 3.86 15.50
Nuclear Periphery Foci -0.52 -13.69 -12.13 -11.27 10.78 -0.11 0.65 -1.84 -0.88 -5.28 -0.19 -11.64 -8.93 -5.79 7.07
Nucleolus 0.36 3.37 5.09 9.69 7.37 1.66 4.41 4.49 6.79 2.75 1.67 5.79 6.35 11.24 7.83
Nucleus 10.40 -14.04 6.27 -3.81 18.88 16.58 -31.07 1.66 -14.48 32.40 17.17 -32.13 5.99 -10.85 37.60
Peroxisomes -9.43 10.06 8.81 14.81 -3.45 -13.26 9.88 7.42 16.78 -2.44 -15.96 13.73 10.89 21.68 -3.06
Vacuole -5.64 -18.50 -25.44 -22.70 -8.13 0.39 -10.18 -15.70 -15.38 -9.00 -3.22 -20.90 -29.42 -27.06 -14.54
Vacuole Periphery -7.24 8.81 3.02 8.11 -1.35 -4.76 7.45 1.87 5.05 -1.48 -6.65 8.52 2.58 6.88 -1.63
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; transcriptionally regulated by Upc2p via an upstream sterol response element; SWAT-GFP fusion protein localizes to the cell periphery, while mCherry fusion localizes to both the cell periphery and vacuole; YHL026C is not an essential gene; in 2005 the start site was moved 141 nt upstream (see Locus History)
Localization
Cell Percentages cytoplasm (56%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-10

YHL026C

YHL026C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yhl026c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available