Standard name
Human Ortholog
Description Protein that binds eIF4G and has a role in repression of translation; has an RGG motif; found in cytoplasmic P bodies; binds to mRNAs under glucose starvation stress, most often in the 5' UTR; found associated with small nucleolar RNAs snR10 and snR11; SBP1 has a paralog, RNP1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0.07 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0.05 0 0 0.06 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.95 0.98 0.95 0.91 0.8 0.68 0.77 0.67 0.67 0.6 0.94 0.9 0.95 0.98 0.98 0.96 0.96 0.93 0.92 0.93 0.95 0.89
Endoplasmic Reticulum 0 0 0.06 0 0.06 0.09 0.16 0.22 0.14 0.18 0.21 0.24 0.05 0.11 0 0 0 0 0 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0.08 0.06 0.13 0.1 0.11 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 1 0 1 1 4 11 16 13 12 7 0 0 2 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 2 0 0 1 0 1 2 0 0 0 2 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 3 8 3 4 4 6 16 10 13 12 19 1 1 2 4 0 2 0 0 2 0 1 1
Cytoplasm 123 207 189 147 208 174 228 202 173 197 129 150 150 188 288 260 279 345 117 192 180 93 228 220
Endoplasmic Reticulum 3 1 11 3 14 17 45 66 31 54 40 60 8 22 13 4 10 16 1 1 10 2 3 9
Endosome 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 1 2 10 25 14 38 19 28 1 5 10 1 1 9 0 0 0 0 0 1
Mitochondria 0 1 0 0 0 1 4 2 13 7 9 3 0 0 0 10 5 4 0 0 0 0 0 1
Nucleus 0 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 1 1 2 0 2 1 12 0 2 1 1 4 4 0 3 2 2 1 4
Unique Cell Count 125 211 198 150 219 192 284 296 224 292 193 251 159 209 302 266 284 360 122 206 197 100 240 247
Labelled Cell Count 126 215 210 153 228 200 298 325 257 326 222 279 161 218 317 282 299 380 122 206 197 100 240 247


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 57.4 46.4 45.7 42.4 49.0 42.3 43.2 40.8 38.4 41.6 40.0 43.3 45.8 50.3 55.1 48.3 62.4 67.5 49.4 51.1 55.4
Std Deviation (1e-4) 12.8 11.5 7.8 10.1 9.6 8.5 9.7 8.6 8.9 10.4 10.2 13.0 7.5 12.3 12.8 15.9 23.0 23.8 14.2 12.8 14.7
Intensity Change (Log2) – – – -0.11 0.1 -0.11 -0.08 -0.17 -0.25 -0.14 -0.19 -0.08 0.0 0.14 0.27 0.08 0.45 0.56 0.11 0.16 0.28

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700020406080WT3HU80HU120HU160020406080WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3020406080WT1AF100AF140AF180020406080
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 3.5 2.6 3.2 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 -1.4 -1.1 -1.2 0.7 0.2 0.2 1.0 1.6 0 0 0 -1.7 0 0
Cytoplasm 1.3 -0.2 -1.9 -4.8 -7.3 -5.3 -7.4 -7.3 -8.7 -0.5 -2.1 0 1.4 1.8 0.2
Endoplasmic Reticulum -1.7 0.4 1.3 3.5 5.0 2.8 4.1 4.5 5.3 -0.2 1.8 -0.6 -2.4 -1.1 -0.6
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 4.2 3.6 5.3 4.5 4.9 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 3.4 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 3.1 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 44.4841 53.0722 45.8594 47.2959 30.6749 49.8019 42.2387 42.9496 42.0487 38.1815 37.5389 44.1961 39.942 48.5653 47.0021 43.0032 37.9615 44.5682
Actin 0.0088 0.0009 0.0157 0.0015 0.0356 0.0019 0.0048 0.022 0.0206 0.0004 0.002 0.0046 0.0185 0.0009 0.0042 0.0024 0.011 0.0023
Bud 0.0015 0.0015 0.0014 0.0053 0.0034 0.0013 0.0015 0.0061 0.0069 0.0013 0.0033 0.0024 0.001 0.0007 0.0013 0.002 0.001 0.0013
Bud Neck 0.0008 0.0009 0.0013 0.0009 0.0008 0.002 0.0009 0.0008 0.0009 0.0004 0.0005 0.0011 0.0013 0.0005 0.0005 0.0008 0.001 0.0011
Bud Periphery 0.0016 0.001 0.0009 0.0027 0.0032 0.0014 0.0011 0.004 0.0106 0.0002 0.0013 0.0011 0.0009 0.0003 0.0006 0.0017 0.0005 0.0005
Bud Site 0.0007 0.001 0.0032 0.0005 0.0019 0.0002 0.0008 0.0177 0.0056 0.0005 0.0004 0.0004 0.0011 0.0005 0.0004 0.0004 0.0055 0.0001
Cell Periphery 0.0026 0.0023 0.0014 0.0022 0.0018 0.0013 0.0027 0.0045 0.0014 0.0002 0.0004 0.0003 0.0025 0.0007 0.0016 0.0031 0.0005 0.0002
Cytoplasm 0.7183 0.9424 0.8145 0.6633 0.6425 0.7605 0.7523 0.859 0.7988 0.8291 0.8923 0.7317 0.7545 0.9476 0.8788 0.6783 0.7962 0.8381
Cytoplasmic Foci 0.0054 0.0023 0.0081 0.0241 0.0254 0.0084 0.0048 0.0039 0.0069 0.0074 0.0184 0.0286 0.0044 0.0032 0.013 0.0136 0.0128 0.0101
Eisosomes 0.0001 0 0.0002 0.0001 0.0002 0 0.0001 0.0007 0.0001 0 0 0 0.0002 0 0 0 0.0012 0
Endoplasmic Reticulum 0.0926 0.018 0.0178 0.0201 0.0069 0.0917 0.0709 0.0218 0.0169 0.0116 0.0055 0.0388 0.0729 0.0156 0.0101 0.0238 0.0026 0.0715
Endosome 0.0287 0.0043 0.0198 0.0329 0.0389 0.0405 0.0318 0.0072 0.025 0.0272 0.0368 0.0804 0.0206 0.0082 0.0215 0.0827 0.0448 0.0392
Golgi 0.0032 0.0012 0.0051 0.0035 0.0476 0.0077 0.0093 0.0049 0.0038 0.0005 0.002 0.0228 0.005 0.0008 0.0035 0.0051 0.0025 0.0062
Lipid Particles 0.0012 0.0003 0.0024 0.017 0.0153 0.0002 0.0009 0.0002 0.0021 0.0002 0.0004 0.0047 0.0022 0.0002 0.0034 0.0037 0.0027 0.0002
Mitochondria 0.0087 0.0014 0.0134 0.0065 0.0803 0.0104 0.0056 0.0273 0.004 0.0005 0.0013 0.0273 0.0136 0.0006 0.0025 0.0019 0.028 0.0042
None 0.0024 0.0003 0.0013 0.0047 0.002 0.0005 0.0015 0.0004 0.0163 0.0008 0.0013 0.0031 0.0019 0.0002 0.0009 0.0003 0.0027 0.0005
Nuclear Periphery 0.0228 0.0018 0.0062 0.0098 0.0058 0.0199 0.014 0.0026 0.0102 0.0199 0.0022 0.0065 0.0268 0.0019 0.0055 0.0107 0.0036 0.0106
Nucleolus 0.0002 0.0001 0.0003 0.0004 0.0021 0 0.0001 0 0.0005 0.0001 0.0001 0.0002 0.0033 0 0.0003 0.0002 0.022 0
Nucleus 0.0047 0.0013 0.002 0.0032 0.0061 0.0022 0.0044 0.0011 0.0054 0.0123 0.0017 0.002 0.0091 0.001 0.0018 0.0028 0.0102 0.0019
Peroxisomes 0.0004 0.0001 0.0051 0.0012 0.0147 0.0001 0.0001 0.0004 0.0013 0.0001 0.0002 0.0006 0.0005 0.0001 0.0011 0.0001 0.0043 0.0001
Punctate Nuclear 0.0003 0 0.0003 0.0052 0.0005 0.0001 0.0001 0.0001 0.0031 0.0012 0.0002 0.0028 0.0072 0 0.0008 0.0001 0.004 0.0001
Vacuole 0.0713 0.016 0.0596 0.1571 0.0473 0.033 0.0688 0.0122 0.042 0.0676 0.022 0.0278 0.043 0.0146 0.0378 0.1184 0.031 0.0075
Vacuole Periphery 0.0233 0.0031 0.0201 0.0378 0.0176 0.0165 0.0234 0.0033 0.0175 0.0186 0.0079 0.0127 0.0098 0.0025 0.0106 0.0478 0.012 0.0042

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 224.4212 189.4734 176.1603 217.0244 244.9014 223.0509 232.1455 233.1223 261.4405 216.1563
Translational Efficiency 3.63 4.0437 3.208 2.6193 2.7676 4.2665 2.7787 2.634 2.3566 3.0474

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1915 833 2611 1959 1664 1680 1596 1811 3579 2513 4207 3770

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 3227.63 2869.66 4320.97 5379.40 2970.30 3126.03 4394.72 5347.28 3107.99 3041.05 4348.95 5363.97
Standard Deviation 563.58 730.69 910.30 1139.69 521.40 564.25 918.05 1096.17 559.30 635.91 913.95 1119.11
Intensity Change Log 2 — -0.169595 0.420880 0.736970 — 0.073723 0.565163 0.848197 — -0.047861 0.491828 0.791345

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000050 0.000215 0.000100 0.000261 0.000060 0.000141 0.000151 0.000183 0.000055 0.000166 0.000120 0.000224
Bud Neck 0.000057 0.000771 0.000633 0.000970 0.000176 0.000421 0.002622 0.000859 0.000112 0.000537 0.001388 0.000917
Bud Site 0.002002 0.009835 0.005368 0.009365 0.002763 0.006088 0.007901 0.007266 0.002356 0.007330 0.006329 0.008356
Cell Periphery 0.005873 0.017984 0.014049 0.045203 0.008994 0.004900 0.006959 0.034789 0.007324 0.009237 0.011359 0.040200
Cytoplasm 0.799796 0.596126 0.709434 0.559290 0.694472 0.673797 0.474541 0.534500 0.750828 0.648051 0.620323 0.547381
Cytoplasmic Foci 0.031685 0.022309 0.012982 0.006311 0.029204 0.023400 0.010529 0.007718 0.030532 0.023038 0.012052 0.006987
Eisosomes 0.000001 0.000003 0.000002 0.000005 0.000001 0.000002 0.000003 0.000003 0.000001 0.000002 0.000003 0.000004
Endoplasmic Reticulum 0.004183 0.002594 0.002742 0.001400 0.004268 0.002451 0.000922 0.000997 0.004222 0.002499 0.002051 0.001207
Endosome 0.001069 0.003118 0.001316 0.001007 0.001724 0.002722 0.002423 0.001150 0.001374 0.002853 0.001736 0.001076
Golgi 0.056246 0.124501 0.039996 0.032881 0.107932 0.098248 0.043032 0.048064 0.080277 0.106950 0.041148 0.040174
Lipid Particles 0.008286 0.023724 0.017886 0.035878 0.011091 0.006460 0.014795 0.032563 0.009590 0.012182 0.016713 0.034285
Mitochondria 0.000453 0.000462 0.000397 0.000421 0.000295 0.000428 0.000230 0.000300 0.000380 0.000439 0.000333 0.000363
Mitotic Spindle 0.000607 0.001538 0.001565 0.001056 0.000986 0.002318 0.002631 0.001326 0.000783 0.002060 0.001970 0.001185
None 0.001319 0.002601 0.000811 0.000990 0.001404 0.000958 0.000765 0.001196 0.001358 0.001502 0.000793 0.001089
Nuclear Periphery 0.000148 0.000442 0.000496 0.000420 0.000308 0.000269 0.000908 0.000467 0.000223 0.000327 0.000652 0.000442
Nuclear Periphery Foci 0.006170 0.017516 0.009704 0.006701 0.012288 0.011540 0.015585 0.008939 0.009015 0.013521 0.011935 0.007776
Nucleolus 0.000025 0.000122 0.000067 0.000160 0.000033 0.000091 0.000162 0.000125 0.000029 0.000101 0.000103 0.000143
Nucleus 0.000688 0.004865 0.003101 0.003593 0.001251 0.002829 0.008723 0.004378 0.000950 0.003504 0.005234 0.003970
Peroxisomes 0.000072 0.000113 0.000090 0.000196 0.000033 0.000043 0.000048 0.000099 0.000054 0.000066 0.000074 0.000149
Vacuole 0.021825 0.087546 0.121256 0.234219 0.034575 0.065000 0.331707 0.243242 0.027753 0.072473 0.201094 0.238553
Vacuole Periphery 0.059445 0.083617 0.058005 0.059674 0.088140 0.097895 0.075363 0.071836 0.072786 0.093162 0.064590 0.065516

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.59 -4.41 -5.08 -1.48 -3.73 -2.70 -3.74 -5.34 -1.69 -0.12 -4.72 -5.62 -6.92 -2.56 -3.33
Bud Neck -6.94 -8.99 -10.21 -2.22 -2.85 -5.15 -12.17 -11.20 -6.66 8.78 -9.17 -14.54 -14.70 -6.45 5.36
Bud Site -6.56 -9.45 -10.33 -0.28 -5.44 -5.11 -7.34 -7.99 -2.33 0.73 -8.61 -11.23 -13.09 -2.49 -3.91
Cell Periphery -7.00 -9.05 -20.49 -10.57 -15.31 5.57 2.92 -14.61 -17.68 -16.35 -2.60 -6.15 -25.08 -21.91 -21.20
Cytoplasm 15.09 11.46 24.82 2.73 14.34 1.89 19.35 14.39 12.51 -5.26 12.47 18.98 27.56 11.83 8.69
Cytoplasmic Foci 3.92 10.27 14.60 9.58 8.62 2.99 10.06 12.51 13.38 3.75 5.04 14.20 19.20 17.03 8.91
Eisosomes -4.89 -4.29 -6.62 -3.37 -4.68 -1.34 -5.35 -8.84 -6.32 -0.31 -4.21 -6.77 -8.91 -6.20 -4.52
Endoplasmic Reticulum 3.44 3.40 7.38 3.66 4.54 3.57 8.07 7.98 4.59 -0.77 4.91 7.07 10.88 5.36 4.43
Endosome -8.73 -3.93 0.58 8.68 3.63 -4.78 -3.57 4.81 7.89 6.87 -9.55 -4.33 3.97 11.42 7.54
Golgi -10.98 5.57 8.22 15.84 4.00 1.97 16.86 14.76 12.85 -2.83 -6.95 16.27 16.27 20.83 0.60
Lipid Particles -7.52 -8.22 -14.30 -4.56 -8.79 4.47 -3.39 -11.66 -15.23 -9.22 -2.76 -8.53 -18.47 -15.48 -12.35
Mitochondria -0.14 0.95 -0.24 -0.01 -0.87 -1.41 0.25 -0.40 1.08 -0.62 -0.79 0.60 -0.38 0.46 -0.86
Mitotic Spindle -4.48 -4.77 -1.28 0.91 1.01 -3.66 -3.11 -1.20 1.78 2.06 -5.18 -5.08 -1.76 2.05 2.12
None -2.04 3.35 0.93 2.35 -0.83 3.26 4.48 0.86 -1.25 -1.98 -0.63 5.47 1.24 1.41 -1.84
Nuclear Periphery -3.69 -13.44 -13.87 0.18 3.13 1.12 -8.32 -5.35 -6.58 6.32 -3.30 -13.07 -12.36 -3.76 6.84
Nuclear Periphery Foci -9.20 -6.04 -1.25 8.99 5.80 0.58 -3.35 3.42 2.91 7.17 -6.03 -5.51 1.97 8.36 8.62
Nucleolus -4.20 -6.81 -14.19 -1.70 -7.92 -1.98 -12.72 -17.40 -0.31 4.49 -3.08 -13.72 -20.61 -1.01 -3.86
Nucleus -5.18 -10.91 -11.83 0.94 -1.40 -2.98 -10.87 -8.19 -3.11 6.75 -5.76 -13.89 -13.46 -1.95 4.92
Peroxisomes -1.63 -0.97 -5.82 -3.16 -6.21 -1.29 -1.86 -5.72 -4.23 -3.96 -1.09 -1.91 -7.63 -6.54 -6.80
Vacuole -13.65 -27.04 -38.71 -20.59 -16.72 -9.17 -41.55 -35.41 -28.10 9.82 -16.77 -44.67 -52.47 -35.96 -6.40
Vacuole Periphery -4.82 0.64 0.38 5.22 -0.28 -1.93 4.89 4.70 6.61 -0.37 -5.86 4.61 3.72 9.20 -1.02
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein that binds eIF4G and has a role in repression of translation; has an RGG motif; found in cytoplasmic P bodies; binds to mRNAs under glucose starvation stress, most often in the 5' UTR; found associated with small nucleolar RNAs snR10 and snR11; SBP1 has a paralog, RNP1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Sbp1

Sbp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sbp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available