Standard name
Human Ortholog
Description Required for splicing of the group I intron bI5 of the COB pre-mRNA; nuclear-encoded mitochondrial protein that binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0.06 0 0 0 0 0 0 0 0 0 0.07 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 – – – – – –
Cell Periphery 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0.05 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.05 0 0 0 0.05 0 0 0 0.09 0.08 0.1 – 0.17 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 0.07 0.12 0.06 0.11 0.1 0.1 0.14 0.05 0 0 0.05 0.09 0 0.17 – 0.17 0.25 0.06 0.09 0.06 0.09 0.07 0.06
Golgi 0 0 0 0.16 0.17 0 0 0 0 0 0 0 0.18 0.23 0.25 – 0.17 0.07 0 0.06 0 0 0.09 0
Mitochondria 0.94 0.81 0.68 0.78 0.67 0.77 0.77 0.76 0.86 0.87 0.89 0.86 0.65 0.67 0.43 – 0 0.09 0.79 0.64 0.72 0.62 0.64 0.72
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nuclear Periphery 0.05 0 0 0 0 0.05 0.06 0 0.05 0 0 0.05 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0.06 0 0 0 0 0 0 0
Peroxisomes 0 0.05 0.07 0 0.07 0 0 0.05 0 0.05 0 0 0 0 0.15 – 0.14 0.22 0.07 0 0.09 0.06 0.07 0
SpindlePole 0 0 0.1 0.06 0.07 0.05 0.07 0.09 0 0 0 0 0 0.06 0.11 – 0.17 0.18 0 0 0 0 0 0
Vac/Vac Membrane 0.08 0.25 0.23 0 0.11 0.1 0.07 0.06 0.07 0.08 0.06 0.05 0.1 0.08 0.1 – 0.17 0.21 0 0.09 0.05 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 2 6 13 2 0 1 3 0 1 0 0 3 6 3 – 0 2 0 3 3 0 3 1
Bud 3 1 0 7 3 4 9 12 7 12 7 7 2 3 1 – 1 2 0 1 1 0 0 2
Bud Neck 0 0 0 0 0 1 0 1 1 0 0 1 0 0 0 – 0 0 0 0 0 0 0 2
Bud Site 0 0 1 0 0 0 2 6 1 1 3 2 0 0 0 – 0 1 – – – – – –
Cell Periphery 3 5 4 13 4 3 2 3 4 2 3 1 4 4 6 – 1 4 0 0 0 0 0 0
Cytoplasm 4 5 3 7 9 9 11 13 13 8 8 7 10 7 14 – 6 8 0 0 0 1 1 1
Endoplasmic Reticulum 3 1 0 2 1 3 3 1 3 1 3 4 1 3 3 – 0 3 0 0 0 0 0 2
Endosome 7 13 12 14 21 30 37 63 15 11 0 18 10 3 23 – 6 23 12 19 9 4 15 12
Golgi 2 7 2 36 32 4 3 3 0 2 0 5 20 20 33 – 6 6 6 13 1 1 19 8
Mitochondria 188 156 66 174 128 235 277 334 245 297 204 311 74 59 58 – 1 8 162 142 101 33 137 137
Nucleus 0 0 0 1 3 7 10 5 2 9 6 7 3 1 2 – 1 4 0 1 0 0 1 1
Nuclear Periphery 10 3 0 2 1 16 20 10 13 8 9 18 0 1 0 – 0 1 2 1 0 0 1 0
Nucleolus 7 3 0 2 2 6 10 18 8 11 8 6 2 1 0 – 2 1 0 1 1 0 1 1
Peroxisomes 7 9 7 7 13 11 10 23 5 16 1 3 5 2 20 – 5 20 14 9 12 3 14 6
SpindlePole 6 6 10 14 13 16 25 38 12 13 6 15 4 5 15 – 6 16 0 4 1 1 2 3
Vac/Vac Membrane 16 48 22 5 21 32 24 26 19 28 13 18 11 7 13 – 6 19 2 19 6 1 10 6
Unique Cell Count 199 192 97 222 192 306 361 440 284 343 228 360 113 88 134 36 91 206 222 141 54 215 190
Labelled Cell Count 257 259 133 297 253 377 444 559 348 420 271 423 149 122 191 41 118 206 222 141 54 215 190


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 5.7 6.3 6.5 7.1 5.9 5.7 6.0 5.2 5.3 5.0 5.1 6.4 6.7 6.7 – 8.1 7.6 5.8 6.8 7.0
Std Deviation (1e-4) 0.8 1.2 1.4 1.2 1.4 1.4 1.1 1.4 1.1 1.2 1.4 0.9 0.9 1.0 1.3 – 2.0 1.9 1.2 1.2 1.1
Intensity Change (Log2) – – – 0.04 0.16 -0.11 -0.16 -0.07 -0.3 -0.27 -0.35 -0.31 0.01 0.07 0.09 – 0.35 0.25 -0.12 0.11 0.15

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.1 0 0 0 0 0 0 0 0 0 0.2 0 – 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Cell Periphery 0.6 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 1.7 0 2.1 – 0 1.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Endosome -1.8 -0.4 -0.7 -0.6 0.5 -2.3 -3.6 0 -2.6 -0.8 -2.2 1.0 – 0 2.3
Golgi 3.6 3.6 0 0 0 0 0 0 0 3.7 4.3 4.7 – 0 0
Mitochondria 2.0 -0.2 1.7 1.8 1.6 4.0 4.2 4.7 4.2 -0.4 -0.1 -3.7 – -6.7 -8.3
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0
Peroxisomes 0 -0.1 0 0 -0.8 0 -1.0 0 0 -0.9 0 1.8 – 0 2.9
SpindlePole -1.2 -1.0 -1.8 -1.1 -0.5 -2.2 -2.5 0 -2.4 -2.0 -1.2 0.2 – 0 1.4
Vacuole -6.0 -2.6 -3.1 -4.7 -5.2 -4.4 -4.0 -4.5 -5.5 -2.6 -2.8 -2.7 – -0.8 -0.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6973 1.7376 1.4497 1.5807 0.8629 1.4444 1.6706 2.2876 2.0498 1.8676 1.2956 1.8662 1.2866 1.6396 1.5121 1.2897 1.4355 1.4794
Actin 0.0331 0.0285 0.0133 0.0058 0.0318 0.0041 0.0127 0.0091 0.0077 0.0228 0.0053 0.0184 0.0418 0.0204 0.0125 0.0016 0.0754 0.0056
Bud 0.0007 0.0017 0.0068 0.0003 0.0004 0.0003 0.0005 0.0005 0.0004 0.0004 0.0002 0.0003 0.0007 0.0057 0.0018 0.005 0.0012 0.0002
Bud Neck 0.0009 0.0006 0.0004 0.0002 0.0058 0.0005 0.0005 0.0006 0.0002 0.0002 0.0003 0.0011 0.0007 0.0011 0.0099 0.0003 0.0046 0.0003
Bud Periphery 0.0012 0.0013 0.0045 0.0008 0.0008 0.0005 0.001 0.0007 0.001 0.0008 0.0005 0.0008 0.0011 0.0094 0.0022 0.0034 0.0017 0.0004
Bud Site 0.0042 0.0145 0.0103 0.0004 0.0017 0.0006 0.0026 0.0085 0.001 0.0008 0.0006 0.0005 0.0019 0.0184 0.0081 0.0044 0.0032 0.0003
Cell Periphery 0.0004 0.0004 0.0013 0.0002 0.0004 0.0002 0.0003 0.0002 0.0001 0.0001 0.0002 0.0002 0.0003 0.0007 0.0004 0.0068 0.0004 0.0003
Cytoplasm 0.0022 0.0119 0.0045 0.0002 0.0007 0.0003 0.0016 0.0004 0.0014 0.0008 0.0004 0.0002 0.002 0.001 0.0054 0.002 0.0042 0.0005
Cytoplasmic Foci 0.0487 0.0304 0.0129 0.007 0.0276 0.0104 0.0253 0.0204 0.0192 0.0361 0.0118 0.0088 0.0288 0.0235 0.0244 0.0273 0.0123 0.0277
Eisosomes 0.0006 0.0003 0.0002 0.0003 0.0008 0.0002 0.0005 0.0002 0.0002 0.0002 0.0001 0.0003 0.0006 0.0005 0.0004 0.0003 0.0007 0.0005
Endoplasmic Reticulum 0.0023 0.0005 0.0011 0.0001 0.0001 0.0003 0.0005 0.0001 0.0004 0.0005 0.0002 0.0003 0.0038 0.0002 0.002 0.0003 0.0028 0.0002
Endosome 0.0444 0.0647 0.0372 0.0253 0.0365 0.0363 0.053 0.0214 0.032 0.0805 0.0245 0.0247 0.0677 0.0342 0.0289 0.029 0.0609 0.0261
Golgi 0.0545 0.0706 0.0328 0.0369 0.0817 0.0307 0.0472 0.0342 0.0352 0.054 0.0236 0.0457 0.0482 0.0507 0.0206 0.0238 0.0743 0.0366
Lipid Particles 0.0499 0.036 0.0109 0.0093 0.0175 0.0238 0.05 0.0187 0.0167 0.039 0.024 0.0252 0.058 0.039 0.0123 0.0155 0.0229 0.0061
Mitochondria 0.7052 0.6885 0.805 0.8959 0.6685 0.8612 0.7102 0.8268 0.82 0.7323 0.8469 0.8045 0.675 0.7352 0.7996 0.8246 0.6681 0.881
None 0.0014 0.0019 0.0062 0.0001 0.0006 0.0001 0.0061 0.0001 0.0006 0.0005 0.0004 0.0001 0.0018 0.0004 0.0071 0.0074 0.0008 0.0006
Nuclear Periphery 0.0027 0.0003 0.0034 0.0001 0 0.0001 0.0052 0.0001 0.0004 0.0004 0.0009 0.0003 0.0022 0.0001 0.0012 0.0002 0.0043 0.0003
Nucleolus 0.0006 0.0006 0.0004 0.0002 0.0001 0.0002 0.001 0.0001 0.0002 0.0004 0.0012 0.0002 0.0005 0.0006 0.0018 0.0014 0.0012 0.0002
Nucleus 0.0006 0.0003 0.0043 0.0001 0.0001 0.0001 0.0012 0.0001 0.0001 0.0002 0.0006 0.0001 0.0005 0.0003 0.0008 0.0005 0.0024 0.0001
Peroxisomes 0.0366 0.031 0.0296 0.0142 0.1232 0.0228 0.0697 0.0555 0.0593 0.0243 0.0404 0.0634 0.0497 0.0453 0.0519 0.0394 0.0499 0.0095
Punctate Nuclear 0.0035 0.0004 0.0004 0.0001 0.0002 0.0001 0.0038 0.0001 0.0002 0.0015 0.0082 0.0002 0.0023 0.0001 0.0008 0.0011 0.0033 0.0002
Vacuole 0.003 0.009 0.0102 0.0013 0.0005 0.0037 0.0044 0.0009 0.002 0.0026 0.0067 0.002 0.0046 0.0044 0.0044 0.003 0.0027 0.001
Vacuole Periphery 0.0033 0.0067 0.0043 0.0014 0.0008 0.0035 0.0028 0.0013 0.0017 0.0017 0.0031 0.0027 0.0081 0.0089 0.0035 0.0027 0.003 0.0024

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.1203 3.6475 8.1197 9.7927 6.0459 5.8256 10.9321 8.0007 7.2389 10.2574
Translational Efficiency 0.6404 0.938 0.7019 0.5917 0.8155 0.8233 0.4132 0.6331 0.7897 0.5359

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
174 434 148 523 2084 1555 265 185 2258 1989 413 708

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 653.20 819.09 960.30 935.62 816.24 774.91 1041.13 1048.56 803.68 784.55 1012.16 965.13
Standard Deviation 80.72 147.67 130.37 134.96 105.88 111.94 117.44 130.22 112.86 122.02 128.23 142.65
Intensity Change Log 2 — 0.326497 0.555960 0.518398 — -0.074965 0.351085 0.361344 — 0.117385 0.445765 0.433276

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000581 0.006493 0.009483 0.029235 0.000981 0.001128 0.009025 0.013427 0.000950 0.002299 0.009189 0.025105
Bud Neck 0.013959 0.004622 0.024864 0.004345 0.000889 0.004509 0.007759 0.010675 0.001897 0.004534 0.013888 0.005999
Bud Site 0.012937 0.014844 0.045089 0.048470 0.003089 0.004895 0.028190 0.076064 0.003848 0.007066 0.034246 0.055680
Cell Periphery 0.003043 0.000460 0.000328 0.001000 0.000168 0.000222 0.000279 0.000569 0.000390 0.000274 0.000297 0.000887
Cytoplasm 0.004464 0.002491 0.004565 0.009151 0.000681 0.002764 0.005390 0.008106 0.000972 0.002704 0.005094 0.008878
Cytoplasmic Foci 0.025112 0.045770 0.115438 0.043560 0.028859 0.037757 0.119406 0.080201 0.028570 0.039505 0.117984 0.053134
Eisosomes 0.000095 0.000118 0.000173 0.000181 0.000048 0.000057 0.000119 0.000138 0.000052 0.000071 0.000138 0.000170
Endoplasmic Reticulum 0.000690 0.000493 0.005370 0.001159 0.000193 0.000288 0.001349 0.001472 0.000231 0.000333 0.002790 0.001241
Endosome 0.041803 0.105199 0.127858 0.080703 0.065851 0.101770 0.170735 0.100329 0.063998 0.102518 0.155370 0.085831
Golgi 0.030415 0.066867 0.080836 0.069545 0.061843 0.075311 0.107718 0.141592 0.059422 0.073469 0.098085 0.088371
Lipid Particles 0.021017 0.004791 0.013965 0.002286 0.004764 0.007125 0.006341 0.001176 0.006017 0.006616 0.009073 0.001996
Mitochondria 0.775181 0.606553 0.180231 0.561647 0.779590 0.681947 0.266417 0.403388 0.779250 0.665496 0.235532 0.520294
Mitotic Spindle 0.001994 0.019627 0.179128 0.039999 0.006605 0.010061 0.111352 0.039098 0.006250 0.012149 0.135640 0.039764
None 0.000499 0.000319 0.000256 0.000254 0.000115 0.000416 0.000165 0.000203 0.000145 0.000395 0.000198 0.000240
Nuclear Periphery 0.000106 0.000210 0.003125 0.000360 0.000323 0.000223 0.000605 0.000104 0.000306 0.000220 0.001508 0.000293
Nuclear Periphery Foci 0.000169 0.000447 0.002722 0.000549 0.000436 0.000442 0.001657 0.000252 0.000416 0.000443 0.002039 0.000471
Nucleolus 0.000578 0.001190 0.004810 0.000074 0.000217 0.001650 0.002122 0.000085 0.000245 0.001549 0.003085 0.000077
Nucleus 0.006771 0.000550 0.011414 0.000157 0.000172 0.001271 0.004134 0.000239 0.000681 0.001114 0.006743 0.000178
Peroxisomes 0.037881 0.102339 0.118715 0.074862 0.032016 0.040573 0.091681 0.080273 0.032468 0.054050 0.101369 0.076276
Vacuole 0.009483 0.009181 0.057715 0.018259 0.005087 0.014156 0.043255 0.029762 0.005425 0.013071 0.048437 0.021265
Vacuole Periphery 0.013221 0.007434 0.013914 0.014206 0.008073 0.013435 0.022302 0.012847 0.008470 0.012126 0.019296 0.013851

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.46 -3.18 -6.45 -4.79 -3.76 -0.31 -3.52 -3.89 -3.82 -1.12 -2.50 -4.64 -7.11 -6.65 -4.16
Bud Neck 2.26 -1.82 2.36 0.22 4.49 -4.58 -4.51 -3.24 -1.98 -0.85 -3.61 -6.13 -4.07 -1.27 3.68
Bud Site -0.36 -3.69 -5.04 -5.41 -0.32 -2.14 -6.06 -6.35 -6.19 -3.95 -3.12 -7.92 -10.22 -9.53 -3.38
Cell Periphery 1.48 1.55 1.16 -2.64 -3.35 -1.87 -3.46 -3.04 -2.61 -2.16 0.84 0.67 -2.47 -4.08 -3.92
Cytoplasm 0.80 -0.14 -1.73 -3.87 -2.50 -3.18 -3.28 -4.87 -3.32 -1.45 -3.09 -4.23 -6.26 -4.57 -2.41
Cytoplasmic Foci -2.93 -6.88 -2.61 0.50 5.86 -3.87 -9.98 -6.10 -4.97 3.22 -5.09 -12.36 -6.45 -3.39 8.17
Eisosomes -1.25 -3.59 -3.61 -2.90 -0.21 -2.23 -6.43 -6.89 -6.29 -1.08 -4.12 -9.02 -8.15 -6.86 -1.78
Endoplasmic Reticulum 0.67 -3.66 -1.08 -1.77 3.27 -1.51 -4.09 -2.30 -2.12 -0.16 -1.61 -5.08 -3.39 -3.02 2.80
Endosome -6.40 -6.86 -4.34 2.54 3.78 -7.18 -9.15 -3.65 0.17 4.94 -8.58 -10.64 -3.77 2.68 7.21
Golgi -4.67 -4.37 -4.99 -0.38 0.94 -3.16 -5.35 -6.07 -4.97 -2.24 -3.72 -5.65 -5.03 -2.49 1.13
Lipid Particles 2.09 0.72 2.48 1.47 2.01 -1.78 -0.84 3.47 4.34 2.68 -0.51 -1.23 3.85 4.16 2.91
Mitochondria 5.88 18.71 7.61 1.82 -13.63 9.02 24.67 13.12 9.54 -3.96 11.34 33.16 16.29 8.76 -13.54
Mitotic Spindle -4.82 -7.74 -8.56 -3.56 5.97 -2.49 -8.81 -6.04 -5.32 5.55 -4.19 -11.44 -9.24 -7.35 8.10
None 1.05 1.85 1.92 0.72 0.07 -3.63 -2.32 -4.57 2.57 -1.39 -3.65 -2.38 -4.34 2.27 -1.60
Nuclear Periphery -1.14 -1.32 -2.54 -1.19 1.21 0.51 -1.15 1.16 1.97 3.10 0.48 -1.43 0.06 -0.87 1.47
Nuclear Periphery Foci -2.00 -3.48 -2.71 -0.50 2.93 -0.04 -2.40 0.77 2.19 3.05 -0.14 -3.66 -0.25 -0.22 3.87
Nucleolus -1.01 -2.98 2.41 1.63 3.37 -3.13 -1.34 1.65 3.43 1.43 -3.37 -2.72 2.32 3.82 2.89
Nucleus 1.41 -1.01 1.51 1.35 4.33 -3.08 -1.51 -0.84 2.89 1.48 -1.08 -3.10 1.43 3.26 3.39
Peroxisomes -5.78 -4.85 -3.80 2.37 2.58 -2.33 -5.44 -3.67 -2.99 0.68 -5.74 -7.57 -6.52 -3.14 2.32
Vacuole 0.08 -5.15 -2.14 -3.16 4.36 -7.93 -6.65 -4.01 -2.57 1.56 -7.58 -8.81 -6.38 -3.24 5.05
Vacuole Periphery 1.60 -0.14 -0.25 -2.41 -0.14 -4.93 -4.17 -1.77 0.23 2.22 -3.69 -4.53 -2.75 -0.85 1.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Required for splicing of the group I intron bI5 of the COB pre-mRNA; nuclear-encoded mitochondrial protein that binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene
Localization
Cell Percentages mitochondrion (96%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Cbp2

Cbp2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cbp2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available