Standard name
Human Ortholog
Description Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0.06 0.08 0.07 0.1 0.06 0.06 0.1
Bud 0.08 0 0.09 0.07 0.1 0.13 0.19 0.15 0.15 0.17 0.14 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0.06 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0.06 0.07 0 0.11 0.07 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.56 0.54 0.54 0.51 0.49 0.33 0.23 0.21 0.15 0.15 0.17 0.19 0.68 0.75 0.74 0.56 0.51 0.5 0.16 0.28 0.1 0.41 0.33 0.28
Endoplasmic Reticulum 0 0.13 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0.07 0.13 0.07 0.12 0 0 0
Endosome 0.05 0.17 0 0.07 0.09 0 0.05 0.09 0.07 0 0.05 0.05 0 0 0 0.14 0.11 0.17 0.09 0.07 0.11 0.06 0.1 0.1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.23 0.06 0.08 0.14 0.16 0.45 0.36 0.3 0.39 0.34 0.44 0.38 0 0 0 0 0 0 0.21 0.19 0.25 0.13 0.17 0.11
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.06 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.06 0.06 0 0.12 0.07 0.1 0.18 0.16 0.13 0.12 0.16 0.11 0 0 0 0.05 0.05 0.05 0 0 0.07 0.05 0 0.09
SpindlePole 0.13 0.13 0.27 0.23 0.2 0.21 0.37 0.44 0.36 0.46 0.35 0.41 0.22 0.19 0.21 0.22 0.29 0.23 0.14 0.18 0.15 0.16 0.15 0.16
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 4 7 1 3 3 0 2 1 5 0 0 20 9 4 4 8 10 7 7 17 9 15 35
Bud 7 2 13 10 14 18 41 43 35 50 39 29 10 7 2 4 10 2 1 2 1 1 4 8
Bud Neck 1 2 5 3 2 2 3 2 5 5 4 1 16 12 7 2 11 4 5 4 2 5 8 13
Bud Site 1 0 5 1 2 4 13 20 8 33 20 24 1 0 1 0 0 0 – – – – – –
Cell Periphery 0 0 1 1 1 2 0 1 0 1 1 0 3 5 2 5 10 4 2 0 3 2 1 5
Cytoplasm 48 42 76 74 65 45 48 59 35 44 46 73 167 201 219 82 150 87 16 32 17 72 84 96
Endoplasmic Reticulum 3 10 2 2 2 3 3 0 4 0 1 4 4 1 1 7 21 12 13 8 19 6 7 8
Endosome 4 13 4 10 12 2 10 26 17 7 14 19 0 4 9 21 32 29 9 8 18 10 25 33
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 1 3 1 0 2 0 0 1
Mitochondria 20 5 11 21 22 61 76 84 89 100 122 144 2 0 1 5 8 2 22 22 42 22 42 39
Nucleus 0 1 0 0 0 0 0 1 2 2 2 3 3 0 0 0 1 2 0 0 0 0 2 1
Nuclear Periphery 0 0 1 0 0 0 0 0 0 0 2 1 0 0 1 0 2 0 0 0 2 0 0 0
Nucleolus 0 0 1 0 0 0 9 18 6 10 13 21 0 0 0 0 4 2 0 0 0 0 1 0
Peroxisomes 5 5 5 17 9 14 38 46 30 34 43 41 2 0 4 7 16 8 3 4 12 8 10 31
SpindlePole 11 10 39 34 27 29 78 125 83 136 97 157 55 50 62 32 86 39 14 20 25 28 37 55
Vac/Vac Membrane 0 2 1 0 2 0 1 7 7 1 6 12 1 0 1 11 14 9 4 2 2 3 8 6
Unique Cell Count 86 78 142 145 134 137 212 281 231 295 276 381 246 268 295 146 295 173 104 116 172 177 253 342
Labelled Cell Count 103 96 172 174 161 183 320 434 322 428 410 529 285 289 314 180 374 213 104 116 172 177 253 342


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.4 4.7 4.2 4.0 4.5 3.8 3.9 4.1 3.9 3.7 3.5 3.6 5.6 5.6 5.6 6.5 6.5 6.6 5.8 6.0 6.0
Std Deviation (1e-4) 0.4 0.6 1.4 1.4 1.8 1.4 1.3 1.8 1.5 1.0 0.9 0.9 1.2 1.1 1.1 1.1 1.5 1.4 1.8 1.7 1.4
Intensity Change (Log2) – – – -0.07 0.07 -0.15 -0.13 -0.06 -0.13 -0.21 -0.27 -0.24 0.4 0.41 0.41 0.62 0.62 0.63 0.44 0.5 0.49

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 – –
Bud Neck – – – – – – – – – – – – 0 – –
Bud Site – – – – – – – – – – – – 0 – –
Cell Periphery – – – – – – – – – – – – 0 – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 – –
Endosome – – – – – – – – – – – – 0 – –
Golgi – – – – – – – – – – – – 0 – –
Mitochondria – – – – – – – – – – – – 0 – –
Nuclear Periphery – – – – – – – – – – – – 0 – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 – –
Peroxisomes – – – – – – – – – – – – 0 – –
SpindlePole – – – – – – – – – – – – 0 – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 – –
Cytoplasm – – – – – – – – – – – – 0 – –
Nucleus – – – – – – – – – – – – 0 – –
Vacuole – – – – – – – – – – – – 2.9 – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.827 1.3975 1.3158 1.1519 1.0744 1.5249 0.3254 0.7618 0.3652 0.4563 0.3529 0.563 -1.1387 -0.1651 -0.7404 -1.0203 -0.5062 -0.6767
Actin 0.0035 0.0014 0.0147 0.0226 0.0074 0.0164 0.0122 0.0123 0.0184 0.0058 0.0341 0.0052 0.008 0.0051 0.0212 0.0119 0.0472 0.0233
Bud 0 0.0001 0.0001 0.0014 0.0013 0.0001 0.0002 0.0006 0.0002 0.0021 0.0004 0 0.0001 0.0001 0.0014 0.0001 0.0004 0.0003
Bud Neck 0.0005 0.0015 0.0019 0.1155 0.024 0.0278 0.0028 0.003 0.0051 0.05 0.0014 0.0332 0.0058 0.0076 0.0107 0.0332 0.001 0.0193
Bud Periphery 0 0.0001 0.0002 0.0013 0.0025 0.0001 0.0003 0.0008 0.0003 0.0056 0.0005 0.0001 0.0001 0.0001 0.0052 0.0001 0.0007 0.0009
Bud Site 0.0005 0.0272 0.0036 0.0094 0.0038 0.0008 0.002 0.0448 0.0065 0.0041 0.0013 0.0004 0.0025 0.0211 0.0076 0.0076 0.0011 0.0011
Cell Periphery 0.0002 0.0003 0.0002 0.0002 0.0005 0.0003 0.0003 0.0011 0.0003 0.0004 0.0003 0.0002 0.0001 0.0002 0.0003 0.0001 0.0001 0.0002
Cytoplasm 0.0717 0.0723 0.0569 0.0788 0.0365 0.1027 0.0948 0.1192 0.106 0.1601 0.1057 0.1559 0.0361 0.0759 0.0517 0.0991 0.0404 0.0388
Cytoplasmic Foci 0.408 0.51 0.4656 0.5104 0.3792 0.4415 0.3899 0.3979 0.5287 0.4149 0.2568 0.4518 0.4719 0.4802 0.4902 0.5858 0.5003 0.5345
Eisosomes 0.0004 0.0001 0.0006 0.0001 0.0007 0.0002 0.0004 0.0003 0.0002 0.0001 0.0005 0.0001 0.0003 0.0001 0.0004 0 0.0006 0.0002
Endoplasmic Reticulum 0.0051 0.0055 0.0087 0.0018 0.0013 0.0044 0.0065 0.0037 0.0052 0.0029 0.0049 0.0059 0.0062 0.0067 0.0072 0.0032 0.0104 0.0034
Endosome 0.0166 0.0326 0.0365 0.0289 0.0274 0.0292 0.1123 0.0481 0.0557 0.0499 0.1207 0.033 0.0324 0.0206 0.0238 0.0304 0.0526 0.0322
Golgi 0.0036 0.0065 0.006 0.0138 0.0085 0.0067 0.0238 0.0079 0.0104 0.0089 0.0324 0.006 0.0068 0.0049 0.0099 0.0084 0.0152 0.0118
Lipid Particles 0.0972 0.1091 0.065 0.0588 0.0341 0.0832 0.062 0.0621 0.067 0.0445 0.0677 0.0662 0.13 0.0972 0.111 0.0895 0.1267 0.0971
Mitochondria 0.0003 0.0006 0.0015 0.0041 0.003 0.0082 0.0139 0.0008 0.0014 0.0123 0.0095 0.0005 0.0006 0.0005 0.0036 0.0006 0.0061 0.0075
None 0.2915 0.1258 0.2332 0.0487 0.4003 0.1807 0.1959 0.175 0.1018 0.1025 0.1883 0.1313 0.1395 0.0575 0.1064 0.0413 0.0364 0.0514
Nuclear Periphery 0.0019 0.0009 0.0028 0.0022 0.0004 0.0005 0.0037 0.0009 0.0009 0.0016 0.001 0.001 0.0032 0.0023 0.002 0.0008 0.0073 0.0019
Nucleolus 0.0013 0.0007 0.0005 0.0007 0.0006 0.0005 0.0005 0.0035 0.0021 0.0005 0.0006 0.0009 0.0004 0.001 0.0005 0.0002 0.0005 0.0009
Nucleus 0.0013 0.0006 0.0007 0.0023 0.0004 0.0007 0.001 0.006 0.0015 0.0023 0.0009 0.0012 0.001 0.0014 0.0012 0.0005 0.0013 0.0011
Peroxisomes 0.0361 0.0683 0.0588 0.0653 0.0458 0.0729 0.0371 0.0705 0.0569 0.0858 0.0769 0.0615 0.0699 0.0949 0.0727 0.0551 0.0775 0.0995
Punctate Nuclear 0.0591 0.0335 0.0396 0.0319 0.0217 0.0216 0.035 0.0371 0.0289 0.0393 0.093 0.0437 0.0839 0.1152 0.072 0.0314 0.0724 0.073
Vacuole 0.0009 0.0026 0.0025 0.0016 0.0006 0.0015 0.0034 0.0042 0.0022 0.0046 0.0023 0.0016 0.0009 0.0072 0.001 0.0005 0.001 0.0012
Vacuole Periphery 0.0001 0.0002 0.0004 0.0004 0.0001 0.0002 0.0018 0.0002 0.0003 0.0018 0.0008 0.0001 0.0003 0.0003 0.0002 0.0001 0.0008 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.8168 8.0911 7.6414 11.8277 5.8675 16.4473 9.4824 14.3058 15.1971 12.8611
Translational Efficiency 0.4166 0.5116 0.5264 0.4824 0.5652 0.2748 0.7737 0.3969 0.5192 0.4163

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
122 394 414 1220 2147 1591 1332 884 2269 1985 1746 2104

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 778.57 781.79 885.57 822.05 706.52 736.65 889.31 925.64 710.39 745.61 888.42 865.57
Standard Deviation 98.62 92.52 85.83 126.23 73.37 82.59 112.95 123.82 76.68 86.55 107.16 135.26
Intensity Change Log 2 — 0.005954 0.185780 0.078399 — 0.060249 0.331956 0.389721 — 0.032040 0.257171 0.234899

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.005386 0.003274 0.002511 0.059945 0.000862 0.001597 0.009545 0.041820 0.001105 0.001930 0.007877 0.052330
Bud Neck 0.028536 0.027056 0.009345 0.018173 0.021089 0.030949 0.010790 0.013988 0.021490 0.030176 0.010447 0.016415
Bud Site 0.062510 0.018778 0.013762 0.096601 0.005146 0.012883 0.024707 0.076920 0.008231 0.014053 0.022112 0.088332
Cell Periphery 0.004720 0.000419 0.000868 0.002023 0.000321 0.000210 0.000708 0.001617 0.000557 0.000252 0.000746 0.001853
Cytoplasm 0.253869 0.158562 0.205010 0.259045 0.232979 0.228219 0.313818 0.244985 0.234102 0.214393 0.288019 0.253138
Cytoplasmic Foci 0.234959 0.434718 0.156479 0.161541 0.421863 0.405204 0.205697 0.158566 0.411813 0.411062 0.194026 0.160291
Eisosomes 0.002457 0.000604 0.000341 0.001832 0.000759 0.000427 0.000694 0.001493 0.000850 0.000462 0.000610 0.001689
Endoplasmic Reticulum 0.067197 0.004222 0.012324 0.017658 0.004109 0.001702 0.006706 0.008848 0.007501 0.002202 0.008038 0.013956
Endosome 0.026491 0.062647 0.009244 0.014681 0.023420 0.045883 0.008394 0.020336 0.023585 0.049211 0.008595 0.017057
Golgi 0.024752 0.022296 0.000469 0.003510 0.009161 0.014301 0.000765 0.009097 0.009999 0.015888 0.000695 0.005857
Lipid Particles 0.125324 0.047689 0.020993 0.024925 0.095985 0.052521 0.022063 0.018297 0.097562 0.051562 0.021809 0.022140
Mitochondria 0.006954 0.011040 0.000458 0.001736 0.004610 0.012143 0.001173 0.004181 0.004736 0.011924 0.001004 0.002763
Mitotic Spindle 0.001966 0.011032 0.002225 0.009310 0.001899 0.013305 0.010564 0.026679 0.001903 0.012854 0.008587 0.016608
None 0.001165 0.001038 0.001961 0.000637 0.003791 0.001999 0.002304 0.001033 0.003650 0.001808 0.002222 0.000803
Nuclear Periphery 0.001849 0.000530 0.002897 0.000594 0.000978 0.000789 0.001370 0.000721 0.001025 0.000737 0.001732 0.000648
Nuclear Periphery Foci 0.018282 0.003866 0.021933 0.008878 0.003543 0.001243 0.011282 0.008095 0.004335 0.001764 0.013807 0.008549
Nucleolus 0.001453 0.001743 0.002068 0.000348 0.002778 0.002787 0.000891 0.000402 0.002707 0.002580 0.001171 0.000371
Nucleus 0.057251 0.037767 0.423749 0.087493 0.090198 0.057741 0.225223 0.092101 0.088426 0.053776 0.272296 0.089429
Peroxisomes 0.036751 0.108921 0.026248 0.063329 0.056636 0.078097 0.065866 0.073999 0.055567 0.084215 0.056472 0.067812
Vacuole 0.034811 0.040521 0.086941 0.167186 0.019295 0.036462 0.077325 0.194362 0.020129 0.037267 0.079605 0.178604
Vacuole Periphery 0.003318 0.003278 0.000173 0.000555 0.000578 0.001539 0.000115 0.002461 0.000726 0.001884 0.000129 0.001356

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.14 1.44 -11.22 -12.58 -12.86 -1.10 -7.62 -8.25 -7.93 -5.98 -1.45 -7.73 -15.60 -15.03 -12.95
Bud Neck 0.19 1.71 1.18 2.39 -2.62 -4.04 4.93 4.33 7.82 -0.38 -3.82 5.33 3.33 7.34 -2.83
Bud Site 3.05 3.20 -1.34 -12.75 -13.01 -4.70 -8.05 -12.73 -10.65 -7.94 -3.31 -6.49 -19.35 -17.47 -14.47
Cell Periphery 4.02 3.62 2.68 -6.17 -4.33 4.46 -8.82 -4.88 -5.41 -3.12 4.46 -2.23 -6.73 -9.31 -6.02
Cytoplasm 3.57 2.60 -0.06 -7.26 -5.66 0.24 -6.23 -0.57 -0.72 4.54 2.14 -3.96 -2.11 -4.12 1.92
Cytoplasmic Foci -7.85 2.78 3.82 20.54 1.46 2.45 23.84 34.03 30.68 8.00 0.78 26.08 37.81 38.07 7.85
Eisosomes 3.36 3.83 1.45 -5.10 -7.26 4.00 1.11 -1.46 -2.69 -1.88 4.66 2.71 -3.66 -6.30 -5.24
Endoplasmic Reticulum 4.77 4.09 3.79 -7.12 -2.23 3.94 -4.42 -4.16 -7.07 -1.14 5.38 -1.26 -4.72 -11.82 -4.70
Endosome -5.16 3.10 3.00 8.46 -0.35 -8.56 8.15 3.00 10.39 -3.94 -10.29 8.54 5.44 14.49 -3.43
Golgi 0.52 5.13 4.61 7.51 -4.16 -4.31 15.68 2.22 4.74 -3.35 -5.13 16.25 6.59 9.77 -4.81
Lipid Particles 4.39 5.99 5.95 3.72 -0.42 9.27 17.38 19.37 10.50 2.84 10.37 18.65 19.67 10.25 1.21
Mitochondria -1.37 3.83 3.16 4.01 -2.45 -5.93 7.87 1.61 5.69 -1.48 -6.32 9.38 4.38 8.25 -1.94
Mitotic Spindle -2.45 -1.61 -3.90 0.21 -2.08 -6.28 -5.63 -6.45 -2.89 -2.09 -6.74 -5.86 -7.75 -1.36 -1.05
None -0.08 -2.10 1.32 1.50 5.03 3.80 2.42 5.17 2.60 3.04 4.10 2.61 6.49 4.79 5.14
Nuclear Periphery 2.21 -1.91 1.99 -0.99 7.65 0.61 -4.40 -1.11 -1.72 3.66 1.25 -5.97 0.73 -0.89 9.33
Nuclear Periphery Foci 1.94 -2.21 1.05 -4.21 4.49 4.01 -7.55 -5.89 -9.71 3.28 3.73 -8.45 -5.98 -11.76 5.56
Nucleolus -0.90 -2.73 1.78 4.25 4.26 -0.36 0.63 7.46 6.64 3.96 -0.01 -0.11 8.36 7.87 5.72
Nucleus 1.78 -17.96 -3.23 -8.71 18.39 7.52 -17.32 -1.29 -6.39 13.82 8.66 -23.68 -1.68 -10.03 22.26
Peroxisomes -5.98 0.98 -2.16 5.38 -4.86 -5.04 -1.26 -0.59 3.17 0.43 -6.96 0.27 -0.61 5.93 -0.80
Vacuole -0.67 -6.97 -19.32 -21.29 -12.05 -7.99 -19.11 -27.29 -25.03 -16.66 -8.71 -21.84 -38.07 -33.96 -20.24
Vacuole Periphery 0.06 3.44 3.11 2.14 -2.48 -4.89 5.74 -1.63 -0.02 -2.43 -3.70 6.48 -0.72 2.44 -3.09
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard
Localization
Cell Percentages ER (11%)
Cell Cycle Regulation No
Subcompartmental Group ER-2

Nem1

Nem1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nem1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available