Standard name
Human Ortholog
Description Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.98 0.97 0.99 0.94 0.92 0.88 0.83 0.81 0.82 0.8 0.99 0.99 0.99 0.95 0.97 0.97 0.96 0.94 0.87 0.95 0.93 0.89
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0 0.15 0.16 0.14 0.26 0.27 0.26 0.29 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 1 0 0 0 0 2 5
Bud 2 1 2 0 0 1 1 7 4 3 1 1 1 0 0 0 0 0 0 0 1 1 1 6
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 1 1 0 7 1 12 11 11 1 6 3 1 2 6 2 3 0 0 0 0 0 1
Cytoplasm 189 268 164 151 267 288 373 532 280 262 124 126 396 666 569 259 127 123 182 259 157 315 494 674
Endoplasmic Reticulum 0 0 0 0 1 2 1 4 0 4 0 0 2 0 0 17 3 4 0 0 1 3 4 17
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 0 0 0 0 2 3 10
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 4 2
Mitochondria 4 4 4 10 8 46 63 83 87 86 40 46 0 0 2 5 1 2 1 2 2 1 3 6
Nucleus 1 1 1 2 1 1 2 10 9 3 1 1 3 7 2 3 2 2 0 1 0 2 1 1
Nuclear Periphery 0 0 1 0 0 0 0 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2
Nucleolus 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 5
Vac/Vac Membrane 0 0 0 0 1 0 3 12 2 3 3 2 1 4 5 3 0 0 1 8 12 2 5 10
Unique Cell Count 191 272 168 155 270 306 406 607 338 323 151 157 400 670 576 274 131 127 190 276 180 333 531 759
Labelled Cell Count 196 275 173 164 278 346 444 662 396 372 170 183 406 678 581 298 137 137 190 276 180 333 531 759


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 7.6 5.8 5.7 6.0 5.3 4.9 5.3 5.0 4.8 4.9 5.1 9.8 9.6 9.5 8.5 10.6 11.3 8.3 8.1 8.5
Std Deviation (1e-4) 0.8 1.1 1.0 0.8 1.1 0.8 1.1 1.0 1.0 1.0 1.2 1.3 1.4 1.4 1.4 1.3 1.7 1.7 1.4 1.5 1.3
Intensity Change (Log2) – – – -0.04 0.04 -0.14 -0.24 -0.13 -0.22 -0.27 -0.24 -0.2 0.75 0.71 0.71 0.55 0.86 0.95 0.51 0.48 0.54

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.1 1.0 -1.7 -2.6 -3.8 -4.8 -5.1 -4.7 -5.0 1.3 2.1 1.1 -1.6 -0.4 -0.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.3 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 1.8 0 4.3 4.5 4.1 6.4 0 6.2 6.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.4978 6.1157 6.0702 6.5456 5.7076 5.668 1.0601 2.2608 2.0718 2.2352 2.2943 2.3633 3.1262 4.7209 4.1977 3.961 3.1867 4.1612
Actin 0.0231 0.0132 0.0093 0.0357 0.011 0.0049 0.0001 0.0003 0.0043 0.0078 0.0002 0.0007 0.0273 0.0008 0.0013 0.0009 0.0396 0.0094
Bud 0.0009 0.0004 0.0002 0.0008 0.001 0.0007 0 0 0.0002 0.0002 0 0.0001 0.0005 0.001 0.0001 0.0001 0.0002 0.0002
Bud Neck 0.0066 0.0006 0.0006 0.0004 0.0007 0.0018 0 0.0001 0.0007 0.0003 0.0001 0.0004 0.0003 0.001 0.0001 0.0003 0.0008 0.0036
Bud Periphery 0.0017 0.0002 0.0002 0.0006 0.0003 0.0006 0 0 0.0001 0.0001 0 0.0001 0.0006 0.0004 0 0.0001 0.0003 0.0001
Bud Site 0.0075 0.0128 0.0013 0.0006 0.0004 0.0003 0.0001 0.0003 0.0003 0.0001 0 0.0003 0.0015 0.0085 0.0002 0.0002 0.0009 0.0035
Cell Periphery 0.0049 0.0006 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0 0 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.7128 0.8862 0.8605 0.9224 0.8453 0.8926 0.7639 0.8 0.842 0.7633 0.5829 0.8448 0.8217 0.9279 0.903 0.9761 0.7886 0.9126
Cytoplasmic Foci 0.0213 0.0083 0.0082 0.0071 0.0078 0.0116 0.0026 0.0021 0.0074 0.0031 0.0017 0.0055 0.0064 0.0027 0.0058 0.0022 0.034 0.0106
Eisosomes 0.0012 0 0.0002 0.0001 0 0 0 0.0001 0 0.0001 0.0001 0 0.0003 0 0 0 0.0003 0
Endoplasmic Reticulum 0.0131 0.0042 0.0041 0.0033 0.0045 0.0032 0.0011 0.003 0.0028 0.0046 0.0005 0.0019 0.0029 0.0038 0.0023 0.0012 0.0009 0.0016
Endosome 0.0209 0.0037 0.0043 0.0029 0.0079 0.0064 0.0004 0.0005 0.0219 0.0026 0.0002 0.0099 0.0028 0.0005 0.001 0.0007 0.0138 0.002
Golgi 0.0078 0.0021 0.0006 0.0023 0.0018 0.0054 0 0.0001 0.015 0.0003 0 0.0017 0.0057 0.0001 0.0003 0.0001 0.0129 0.0017
Lipid Particles 0.0121 0.0003 0.0009 0.003 0.0012 0.0011 0 0.0002 0.0005 0 0 0.0018 0.0093 0.0001 0.0008 0 0.0172 0.0006
Mitochondria 0.0071 0.0005 0.0033 0.0004 0.0007 0.0015 0 0 0.0034 0.0001 0 0.0021 0.0024 0.0001 0.0001 0.0001 0.0404 0.0003
None 0.1114 0.06 0.0912 0.0092 0.0806 0.0527 0.2307 0.1915 0.0967 0.2147 0.4134 0.1268 0.1012 0.0502 0.0828 0.016 0.0109 0.0476
Nuclear Periphery 0.0057 0.001 0.0016 0.0014 0.003 0.0016 0.0002 0.0005 0.0007 0.0008 0.0001 0.0008 0.0007 0.0004 0.0004 0.0003 0.0004 0.0003
Nucleolus 0.0015 0.0001 0.0006 0 0.0009 0.0003 0 0 0 0 0 0.0001 0.0001 0 0 0 0.0001 0
Nucleus 0.0068 0.0029 0.0071 0.0024 0.0231 0.0051 0.0003 0.0006 0.0011 0.001 0.0005 0.0009 0.003 0.0014 0.0007 0.0011 0.0007 0.001
Peroxisomes 0.006 0.0005 0.0024 0.005 0.0013 0.0044 0 0 0.0003 0.0001 0 0.0003 0.0122 0.0001 0.0004 0 0.0354 0.0034
Punctate Nuclear 0.0221 0.0007 0.0014 0.001 0.0075 0.0046 0.0002 0.0002 0.0003 0.0002 0.0002 0.0005 0.0006 0.0005 0.0002 0.0002 0.0017 0.001
Vacuole 0.0044 0.0015 0.0015 0.0011 0.0007 0.0009 0.0002 0.0003 0.0016 0.0004 0.0001 0.0008 0.0003 0.0003 0.0003 0.0002 0.0004 0.0003
Vacuole Periphery 0.001 0.0001 0.0002 0.0002 0.0002 0.0002 0 0 0.0005 0.0001 0 0.0003 0.0001 0 0 0 0.0002 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 57.9077 53.9621 51.6823 56.4076 55.9686 65.9431 57.8917 58.6631 59.7904 59.8566
Translational Efficiency 0.5259 0.6066 0.5765 0.5746 0.4832 0.4782 0.6279 0.5246 0.5251 0.4326

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
225 518 1127 1141 941 1680 234 1713 1166 2198 1361 2854

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 874.86 935.51 1535.08 1217.74 795.66 814.56 1384.75 1229.71 810.94 843.06 1509.23 1224.92
Standard Deviation 101.74 141.66 238.04 175.09 146.87 115.43 218.88 166.24 142.77 132.47 241.61 169.94
Intensity Change Log 2 — 0.096701 0.811190 0.477082 — 0.033869 0.799402 0.628094 — 0.067115 0.805587 0.550982

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000288 0.000264 0.000283 0.002350 0.000201 0.000704 0.000552 0.000977 0.000218 0.000600 0.000329 0.001526
Bud Neck 0.001089 0.001531 0.001216 0.003259 0.001570 0.004597 0.001497 0.003569 0.001477 0.003874 0.001264 0.003445
Bud Site 0.005391 0.008819 0.002619 0.022753 0.004695 0.010081 0.003195 0.026081 0.004830 0.009783 0.002718 0.024750
Cell Periphery 0.000232 0.000083 0.000116 0.000129 0.000134 0.000049 0.000178 0.000142 0.000153 0.000057 0.000127 0.000137
Cytoplasm 0.704646 0.757153 0.636252 0.648578 0.694600 0.743052 0.648414 0.651412 0.696538 0.746375 0.638343 0.650279
Cytoplasmic Foci 0.132379 0.082693 0.004977 0.025564 0.111960 0.092263 0.009363 0.014922 0.115900 0.090008 0.005731 0.019176
Eisosomes 0.000059 0.000021 0.000004 0.000018 0.000040 0.000023 0.000009 0.000015 0.000043 0.000022 0.000005 0.000016
Endoplasmic Reticulum 0.001640 0.001542 0.000540 0.001140 0.002250 0.000515 0.000831 0.001637 0.002132 0.000757 0.000590 0.001438
Endosome 0.008498 0.005893 0.000905 0.004919 0.009372 0.007287 0.000963 0.004154 0.009203 0.006959 0.000915 0.004460
Golgi 0.001268 0.001323 0.000439 0.014998 0.002107 0.002419 0.000273 0.003407 0.001945 0.002161 0.000411 0.008041
Lipid Particles 0.002730 0.000796 0.000585 0.001051 0.002543 0.001362 0.001026 0.000910 0.002579 0.001228 0.000661 0.000966
Mitochondria 0.004127 0.002136 0.000285 0.003589 0.001718 0.001542 0.000180 0.008343 0.002183 0.001682 0.000267 0.006442
Mitotic Spindle 0.002852 0.001807 0.005893 0.045286 0.001701 0.002468 0.003553 0.081260 0.001923 0.002312 0.005491 0.066878
None 0.001609 0.003550 0.010765 0.011121 0.008093 0.003391 0.005859 0.006210 0.006842 0.003429 0.009922 0.008173
Nuclear Periphery 0.000161 0.000154 0.000449 0.000677 0.000291 0.000165 0.000463 0.000411 0.000265 0.000162 0.000452 0.000517
Nuclear Periphery Foci 0.005240 0.003220 0.002228 0.004623 0.003806 0.001213 0.006916 0.001952 0.004083 0.001686 0.003034 0.003019
Nucleolus 0.000316 0.000261 0.000150 0.000220 0.000776 0.000578 0.000118 0.000222 0.000688 0.000503 0.000145 0.000221
Nucleus 0.055971 0.058495 0.309768 0.132206 0.076666 0.046515 0.247187 0.114776 0.072673 0.049338 0.299008 0.121744
Peroxisomes 0.000725 0.001592 0.000081 0.000448 0.000782 0.002454 0.000059 0.002595 0.000771 0.002251 0.000077 0.001737
Vacuole 0.069776 0.067392 0.022223 0.075596 0.075785 0.078059 0.069259 0.071871 0.074626 0.075545 0.030310 0.073360
Vacuole Periphery 0.001003 0.001275 0.000220 0.001476 0.000910 0.001262 0.000105 0.005136 0.000928 0.001265 0.000200 0.003673

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.40 -2.54 -2.49 -2.63 -1.86 -1.42 -6.81 -2.93 0.45 2.21 -1.41 -7.74 -3.80 -0.49 -1.27
Bud Neck -2.41 -7.15 -9.36 -7.73 -4.71 -5.39 -3.75 -5.92 1.55 -2.71 -5.53 -5.71 -9.37 -0.08 -4.82
Bud Site -2.03 1.99 -5.25 -2.82 -6.62 -4.85 -1.88 -6.26 -1.64 -5.09 -5.30 1.24 -8.45 -3.01 -8.85
Cell Periphery 6.67 1.36 4.63 -5.17 4.51 9.10 -4.83 4.05 -5.38 6.87 10.90 -3.74 4.93 -9.10 7.94
Cytoplasm -2.38 8.60 11.06 17.52 4.52 -4.63 8.51 13.69 21.44 -0.26 -5.24 14.17 17.94 28.21 3.22
Cytoplasmic Foci 5.17 14.88 13.05 12.38 -9.10 3.57 21.08 20.28 21.79 -2.92 5.44 27.45 23.89 25.07 -11.40
Eisosomes 6.02 8.47 6.64 1.23 -10.93 6.37 9.06 10.31 6.15 1.07 8.54 14.96 11.87 5.56 -9.50
Endoplasmic Reticulum 0.33 3.12 3.43 1.36 0.85 5.70 3.76 5.55 0.05 3.61 4.86 5.17 6.12 1.05 2.66
Endosome 2.27 8.28 7.01 3.80 -3.59 2.49 11.03 10.68 8.90 -0.94 3.18 13.21 12.10 9.50 -3.48
Golgi 0.04 1.51 -0.94 -1.02 -2.00 -0.30 2.62 2.06 3.15 -1.01 -0.23 2.73 0.94 1.42 -2.11
Lipid Particles 2.57 1.98 0.36 -8.87 -6.79 3.53 1.05 1.56 -2.80 0.24 4.49 4.54 1.24 -5.01 -6.18
Mitochondria 0.66 1.31 1.17 0.77 -1.33 0.23 2.05 0.46 0.28 -1.79 0.58 2.27 1.25 0.82 -1.94
Mitotic Spindle 0.38 -1.53 -9.22 -10.71 -9.43 -0.83 -2.53 -14.59 -14.44 -9.84 -0.46 -4.58 -17.74 -17.86 -15.67
None -2.61 -18.48 -10.02 -5.68 0.65 2.80 1.45 0.19 -7.28 -2.52 2.55 -1.15 -0.91 -9.03 0.69
Nuclear Periphery -0.23 -15.84 -15.32 -15.72 -2.97 2.43 -6.47 -17.30 -16.73 -0.58 2.48 -14.70 -21.26 -20.92 -2.97
Nuclear Periphery Foci 2.30 2.88 -0.87 -3.46 -4.19 8.60 -4.52 1.84 -7.33 5.46 8.01 0.40 -0.64 -8.07 -0.99
Nucleolus 1.12 2.54 -2.02 -2.59 -3.18 1.50 6.12 0.51 -0.73 -4.39 1.79 5.89 0.37 -1.29 -5.10
Nucleus -0.69 -39.11 -15.60 -15.18 25.55 7.73 -12.08 -10.79 -22.68 7.89 6.87 -39.53 -16.07 -28.61 29.99
Peroxisomes -1.74 2.56 1.08 2.66 -3.28 -4.46 6.53 0.43 4.21 -2.60 -4.79 6.63 1.11 5.14 -3.40
Vacuole -0.94 0.95 -13.70 -13.96 -17.90 -1.00 -6.70 -16.84 -17.56 -1.11 -1.26 -1.04 -21.85 -22.89 -19.17
Vacuole Periphery -0.21 1.68 1.43 1.28 -1.04 -0.82 5.95 0.61 1.09 -1.83 -0.82 4.95 1.62 1.83 -1.83
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Tda3

Tda3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tda3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available