Standard name
Human Ortholog
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Cytoplasm – 0.62 0.84 0.83 0.8 0.82 0.92 0.82 0.64 0.64 0.47 0.35 0.84 0.9 0.93 0.27 0.26 0.28 – 0.72 0.44 0.64 0.63 0.47
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Endosome – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.14 – 0 0 0 0 0
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Mitochondria – 0.48 0 0 0 0.1 0.08 0.14 0.47 0.3 0.63 0.82 0 0 0 0.08 0.18 0.08 – 0.08 0.19 0 0 0.08
Nucleus – 0 0 0.1 0.07 0 0 0 0 0.05 0 0 0.05 0 0 0.59 0.44 0.42 – 0 0.08 0.07 0.06 0
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Nucleolus – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
SpindlePole – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0.08 0.06 0 0.1
Vac/Vac Membrane – 0.14 0.06 0.07 0.13 0.1 0 0.07 0.05 0 0 0 0.07 0.05 0.06 0.06 0.16 0.19 – 0.06 0 0.06 0.08 0.1
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 1 0 2 3
Bud – 0 0 0 0 0 1 0 1 2 0 0 0 0 0 0 0 1 – 0 0 2 4 5
Bud Neck – 0 2 0 0 2 1 5 0 0 0 1 0 0 1 0 0 0 – 0 0 0 3 2
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 2 2 0 0 1 1 0 1 0 0 0 5 0 0 0 – 0 0 0 1 0
Cytoplasm – 13 66 33 37 87 115 147 47 47 27 18 70 113 146 14 30 25 – 50 36 47 76 71
Endoplasmic Reticulum – 0 0 1 0 0 0 0 0 0 0 1 2 1 3 2 5 3 – 0 0 0 0 3
Endosome – 0 2 0 1 3 1 1 0 0 0 0 0 3 2 2 11 13 – 3 2 0 1 2
Golgi – 0 2 0 0 0 0 0 0 0 0 0 1 1 1 1 0 0 – 0 1 0 0 2
Mitochondria – 10 0 0 0 11 10 25 35 22 36 42 0 0 0 4 20 7 – 5 15 2 2 12
Nucleus – 0 3 4 3 1 3 7 1 4 0 2 4 2 1 30 50 38 – 2 6 5 7 6
Nuclear Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 – 0 0 0 0 1
Nucleolus – 0 0 0 0 1 0 0 1 0 2 1 0 0 0 1 4 1 – 0 1 1 1 2
Peroxisomes – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0
SpindlePole – 0 3 0 0 0 1 5 2 3 1 0 0 1 0 1 2 3 – 1 6 4 3 14
Vac/Vac Membrane – 3 5 3 6 11 3 12 4 3 2 1 6 6 10 3 18 17 – 3 3 4 9 15
Unique Cell Count 21 79 40 46 106 125 179 74 74 57 51 83 126 157 51 114 90 70 82 75 120 153
Labelled Cell Count 26 83 43 49 116 135 203 92 81 69 66 83 127 169 58 141 108 70 82 75 120 153


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 3.4 5.0 4.7 5.8 4.2 4.1 4.7 3.6 4.1 4.0 3.7 5.3 5.4 5.1 4.9 5.9 5.6 6.4 5.4 6.4
Std Deviation (1e-4) – 1.1 1.5 1.0 2.2 1.2 1.4 2.0 2.0 1.6 1.9 1.3 1.9 1.7 1.8 2.0 2.6 1.8 2.8 2.1 3.1
Intensity Change (Log2) – – – -0.11 0.21 -0.25 -0.29 -0.1 -0.47 -0.31 -0.34 -0.45 0.07 0.09 0.02 -0.04 0.24 0.15 0.34 0.09 0.35


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – 0 0
Bud Neck – – – – – – – – – – – – – 0 0
Bud Site – – – – – – – – – – – – – 0 0
Cell Periphery – – – – – – – – – – – – – 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – 0 0
Endosome – – – – – – – – – – – – – 0 0
Golgi – – – – – – – – – – – – – 0 0
Mitochondria – – – – – – – – – – – – – 0 0
Nuclear Periphery – – – – – – – – – – – – – 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – 0 0
Peroxisomes – – – – – – – – – – – – – 0 0
SpindlePole – – – – – – – – – – – – – 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – 0 0
Cytoplasm – – – – – – – – – – – – – 0 0
Nucleus – – – – – – – – – – – – – 0 0
Vacuole – – – – – – – – – – – – – 2.0 2.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.2766 0.0327 0.0026 0.1921 0.3616 0.0008 – – – – – – 0.0428 0.0002 0.013 0.0008 0.0004 0.0222
Bud 0.0023 0.001 0.0033 0.0012 0.0004 0.0001 – – – – – – 0.0006 0.0001 0.0006 0.0005 0.0002 0.0007
Bud Neck 0.0502 0.0015 0.0009 0.0024 0.0029 0.0096 – – – – – – 0.0077 0.0005 0.0009 0.0019 0.0033 0.0292
Bud Periphery 0.004 0.0016 0.0025 0.0012 0.0005 0.0001 – – – – – – 0.0008 0.0001 0.0009 0.0008 0.0002 0.0014
Bud Site 0.0128 0.0049 0.0044 0.007 0.001 0.0001 – – – – – – 0.0145 0.001 0.0008 0.0014 0.0005 0.0011
Cell Periphery 0.0024 0.0002 0.0001 0.0001 0.0002 0 – – – – – – 0.0006 0.0001 0.0002 0.0003 0 0.0002
Cytoplasm 0.0151 0.0663 0.0607 0.0417 0.0124 0.1095 – – – – – – 0.0718 0.1056 0.0759 0.1376 0.1218 0.1307
Cytoplasmic Foci 0.0441 0.0082 0.0096 0.023 0.0133 0.0037 – – – – – – 0.0201 0.0069 0.0243 0.0152 0.0014 0.0449
Eisosomes 0.003 0.0003 0.0001 0.0005 0.0011 0.0002 – – – – – – 0.0005 0.0002 0.0001 0.0001 0 0.0002
Endoplasmic Reticulum 0.0101 0.001 0.0033 0.0002 0.0084 0.0014 – – – – – – 0.003 0.0026 0.003 0.0031 0.0025 0.0039
Endosome 0.097 0.0014 0.0105 0.0024 0.0296 0.0016 – – – – – – 0.0149 0.0026 0.0034 0.0644 0.0018 0.0128
Golgi 0.0332 0.0025 0.0016 0.0159 0.0214 0.0001 – – – – – – 0.0047 0.0002 0.0009 0.0077 0.0001 0.0099
Lipid Particles 0.06 0.0011 0.0012 0.0207 0.0134 0.0004 – – – – – – 0.0161 0.0032 0.0006 0.0061 0.0001 0.0068
Mitochondria 0.021 0.0143 0.0058 0.009 0.0018 0.0004 – – – – – – 0.0046 0.0008 0.0013 0.0059 0.0007 0.0323
None 0.22 0.7185 0.5676 0.2785 0.4975 0.4463 – – – – – – 0.2648 0.4672 0.3608 0.4054 0.3764 0.3563
Nuclear Periphery 0.0228 0.0037 0.0344 0.0011 0.0123 0.011 – – – – – – 0.0223 0.012 0.009 0.0107 0.0254 0.0132
Nucleolus 0.0095 0.0031 0.0038 0.0005 0.0004 0.0049 – – – – – – 0.0088 0.0079 0.0076 0.0052 0.0094 0.0073
Nucleus 0.0093 0.117 0.2127 0.3438 0.0013 0.3622 – – – – – – 0.4101 0.3394 0.4121 0.1949 0.3453 0.279
Peroxisomes 0.0394 0.0016 0.0011 0.0566 0.0059 0.0001 – – – – – – 0.005 0.0003 0.0002 0.0014 0.0001 0.0039
Punctate Nuclear 0.0236 0.0181 0.0682 0.0019 0.0136 0.0468 – – – – – – 0.08 0.0467 0.0816 0.1117 0.1078 0.04
Vacuole 0.0365 0.0009 0.0035 0.0002 0.0004 0.0007 – – – – – – 0.0051 0.0019 0.0024 0.0195 0.0023 0.0029
Vacuole Periphery 0.0072 0.0002 0.0022 0.0001 0.0008 0.0002 – – – – – – 0.0013 0.0004 0.0006 0.0054 0.0004 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 44.4499 51.4225 54.3458 32.9654 38.4209 64.4603 43.7215 43.599 58.006 43.0006
Translational Efficiency 0.4862 0.4028 0.3769 0.7953 0.7189 0.3363 0.4389 0.6168 0.4112 0.5059

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
31 214 1749 14 46 199 110 36 77 413 1859 50

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 681.56 802.06 831.25 774.14 710.98 857.74 830.10 900.24 699.14 828.89 831.18 864.93
Standard Deviation 109.86 144.70 110.74 89.97 119.30 146.73 115.73 304.20 116.49 148.32 111.04 268.51
Intensity Change Log 2 — 0.234869 0.286442 0.183754 — 0.270731 0.223476 0.340501 — 0.253291 0.254637 0.265908

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000323 0.002257 0.000953 0.000232 0.000636 0.002112 0.001164 0.001530 0.000510 0.002187 0.000966 0.001167
Bud Neck 0.004140 0.015872 0.030451 0.008090 0.008065 0.011461 0.009607 0.005792 0.006485 0.013747 0.029217 0.006435
Bud Site 0.009383 0.030216 0.019525 0.004688 0.005731 0.020130 0.016091 0.091010 0.007201 0.025356 0.019322 0.066840
Cell Periphery 0.000300 0.000366 0.000217 0.000249 0.000259 0.000211 0.000255 0.000266 0.000276 0.000291 0.000220 0.000261
Cytoplasm 0.263779* 0.171947* 0.078893 0.522783* 0.155001* 0.115988* 0.238291* 0.235885* 0.198795* 0.144984* 0.088325 0.316217*
Cytoplasmic Foci 0.041304 0.028467 0.001597 0.126783 0.014569 0.052957 0.009928 0.012324 0.025333 0.040267 0.002090 0.044372
Eisosomes 0.000116 0.000083 0.000039 0.000131 0.000082 0.000091 0.000068 0.000064 0.000096 0.000087 0.000041 0.000083
Endoplasmic Reticulum 0.004253 0.010488 0.005699 0.002150 0.004854 0.005721 0.011566 0.006015 0.004612 0.008191 0.006046 0.004933
Endosome 0.005430 0.013433 0.001523 0.015803 0.002810 0.019303 0.005524 0.002180 0.003865 0.016261 0.001760 0.005995
Golgi 0.000982 0.007850 0.000401 0.000349 0.000287 0.011629 0.000690 0.001031 0.000567 0.009671 0.000418 0.000840
Lipid Particles 0.007464 0.006633 0.000773 0.007791 0.003457 0.005588 0.002339 0.002046 0.005070 0.006130 0.000866 0.003655
Mitochondria 0.004192 0.010407 0.005778 0.000518 0.001312 0.020167 0.001093 0.000841 0.002471 0.015110 0.005501 0.000750
Mitotic Spindle 0.003069 0.047751 0.033187 0.003255 0.058889 0.110457* 0.023054 0.016188 0.036416 0.077965 0.032587 0.012567
None 0.040499 0.035785 0.008871 0.021706 0.016406 0.020853 0.017071 0.004772 0.026106 0.028590 0.009356 0.009514
Nuclear Periphery 0.002104 0.002593 0.002767 0.001760 0.002162 0.002991 0.003403 0.005518 0.002139 0.002785 0.002805 0.004466
Nuclear Periphery Foci 0.001701 0.004782 0.000607 0.003255 0.001504 0.005816 0.005929 0.007725 0.001583 0.005280 0.000922 0.006473
Nucleolus 0.009954 0.010076 0.006312 0.004631 0.015560 0.010327 0.001565 0.000863 0.013303 0.010197 0.006032 0.001918
Nucleus 0.499630* 0.551229* 0.786755* 0.139744* 0.685983* 0.491856* 0.554851* 0.455956* 0.610957* 0.522621* 0.773033* 0.367417*
Peroxisomes 0.001463 0.004724 0.000351 0.001568 0.001341 0.025240 0.000391 0.000379 0.001390 0.014610 0.000353 0.000712
Vacuole 0.069212 0.039823 0.013523 0.134018 0.020576 0.063973 0.096405 0.073091 0.040157 0.051460 0.018427 0.090151
Vacuole Periphery 0.030702 0.005217 0.001778 0.000496 0.000516 0.003130 0.000716 0.076523 0.012669 0.004211 0.001715 0.055235

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin NaN NaN NaN NaN NaN -0.16 0.13 -0.94 -0.94 -1.32 -1.63 -0.42 -1.13 0.06 -1.06
Bud Neck NaN NaN NaN NaN NaN 0.23 0.48 0.61 0.41 0.22 -2.30 -7.22 -0.01 2.09 6.60
Bud Site NaN NaN NaN NaN NaN -1.00 0.07 -1.80 -1.63 -1.81 -2.07 -1.54 -1.76 -1.36 -1.57
Cell Periphery NaN NaN NaN NaN NaN 1.28 1.04 0.11 -1.67 -1.31 0.76 1.83 0.32 -0.47 -1.81
Cytoplasm NaN NaN NaN NaN NaN -0.41 -0.46 -0.70 -0.49 -0.38 0.97 3.39 -1.00 -2.10 -4.22
Cytoplasmic Foci NaN NaN NaN NaN NaN -2.20 1.01 0.39 2.77 -0.64 -0.17 3.70 -0.67 -0.62 -2.78
Eisosomes NaN NaN NaN NaN NaN -0.06 0.75 -0.12 -0.09 -0.84 1.18 4.15 -0.48 -1.50 -3.76
Endoplasmic Reticulum NaN NaN NaN NaN NaN -0.61 -3.19 -1.45 -1.24 0.47 -2.11 -0.56 -1.21 -0.15 -1.06
Endosome NaN NaN NaN NaN NaN -3.72 -1.54 -0.83 2.85 0.38 -3.43 3.90 -1.43 0.95 -2.80
Golgi NaN NaN NaN NaN NaN -1.82 0.62 -0.50 1.75 -0.86 -2.47 1.52 0.15 2.49 -1.15
Lipid Particles NaN NaN NaN NaN NaN -1.43 1.12 -0.22 1.21 -1.41 -0.36 3.47 -0.21 0.11 -3.39
Mitochondria NaN NaN NaN NaN NaN -2.18 0.40 0.87 2.26 0.68 -2.53 -2.69 1.74 3.21 6.88
Mitotic Spindle NaN NaN NaN NaN NaN -0.51 0.99 0.21 0.80 -0.73 -1.26 0.43 -0.07 1.03 -0.47
None NaN NaN NaN NaN NaN -0.23 0.73 2.34 1.82 1.93 0.42 1.38 1.43 2.45 0.37
Nuclear Periphery NaN NaN NaN NaN NaN -1.91 -1.82 -1.56 -0.36 -0.74 -2.24 -1.78 -1.28 0.05 -0.51
Nuclear Periphery Foci NaN NaN NaN NaN NaN -0.12 0.49 -0.74 -0.79 -1.32 -0.69 1.09 -0.96 -0.63 -1.86
Nucleolus NaN NaN NaN NaN NaN 1.07 2.68 2.57 2.76 -0.72 0.71 1.91 2.88 4.03 4.17
Nucleus NaN NaN NaN NaN NaN 2.26 0.78 2.66 1.21 2.38 0.72 -5.10 3.58 3.73 8.83
Peroxisomes NaN NaN NaN NaN NaN -2.55 3.03 1.98 2.81 -1.92 -2.96 3.88 1.02 3.19 -2.19
Vacuole NaN NaN NaN NaN NaN -1.43 -2.53 -2.48 -1.80 -0.81 -0.11 2.88 -3.25 -3.48 -5.09
Vacuole Periphery NaN NaN NaN NaN NaN -1.40 1.17 -0.99 -0.94 -1.00 0.81 1.01 -0.40 -0.88 -0.98
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance
Localization
Cell Percentages nucleus (63%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Srb2

Srb2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Srb2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available