Standard name
Human Ortholog
Description Arginine/alanine amino peptidase; overproduction stimulates glycogen accumulation; AAP1 has a paralog, APE2, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.97 0.97 0.99 0.97 0.93 0.9 0.87 0.82 0.83 0.86 0.98 0.99 0.99 0.99 0.99 0.99 0.97 0.91 0.95 0.91 0.91 0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0.06 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.12 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 3 1 3 1 4 3 0 0 0 0 0 0 0 0 0 1 0 1
Bud 0 0 0 0 0 1 0 0 3 3 1 1 2 0 2 0 0 0 0 1 1 0 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 4 5 5 8 17 6 11 8 8 7 4 4 6 3 1 6 0 0 0 0 0 0
Cytoplasm 193 146 266 164 295 284 438 369 261 247 213 242 313 448 613 286 196 221 185 135 252 201 353 412
Endoplasmic Reticulum 0 0 4 2 1 4 21 24 11 6 5 14 1 2 7 11 5 4 0 0 0 8 9 12
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1
Mitochondria 1 1 0 1 0 1 2 2 9 10 15 2 1 1 0 1 0 0 0 0 2 0 2 0
Nucleus 0 0 1 2 3 3 6 7 3 6 6 2 3 1 4 2 1 0 0 4 2 0 2 6
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 3 3 1 2 6 16 10 37 19 22 2 4 3 4 2 6 0 4 6 2 11 12
Unique Cell Count 194 147 273 169 299 292 469 411 299 303 258 283 320 454 622 290 198 224 191 149 267 221 387 461
Labelled Cell Count 194 149 278 177 305 303 493 425 312 318 271 294 327 461 636 308 205 237 191 149 267 221 387 461


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 33.8 27.4 25.1 20.9 21.6 18.7 17.9 17.0 14.6 13.3 13.1 13.9 26.6 27.4 27.2 42.5 39.4 41.4 25.7 26.9 29.1
Std Deviation (1e-4) 6.9 7.0 5.4 5.4 4.1 4.2 4.1 3.7 3.6 3.4 3.9 3.6 6.2 6.3 6.1 12.4 11.4 9.9 5.2 6.1 7.0
Intensity Change (Log2) – – – -0.27 -0.22 -0.42 -0.49 -0.56 -0.78 -0.92 -0.94 -0.85 0.08 0.13 0.11 0.76 0.65 0.72 0.04 0.1 0.21


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 1.1 1.7 0 1.7 1.0 1.3 0.9 0 0 0 0 0 0
Cytoplasm -0.2 1.1 -0.1 -2.4 -3.8 -4.5 -6.1 -5.8 -5.0 0.3 1.2 1.2 1.0 1.2 1.0
Endoplasmic Reticulum 0 0 0 2.2 2.8 1.7 0 0 2.3 0 0 0 1.7 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 4.0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.2 1.8 5.2 3.6 3.8 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 16.2851 22.6154 19.8754 16.1759 19.0469 20.6804 18.7289 26.4922 23.0856 22.3716 20.9291 23.141 11.0618 19.6598 16.4805 19.6283 20.0081 18.7302
Actin 0.0083 0.0003 0.0012 0.0631 0.0565 0.0005 0.0155 0.0001 0.0025 0.0011 0.004 0 0.0206 0.0098 0.0338 0.0001 0 0.0001
Bud 0.0004 0 0.0002 0.0002 0.0002 0.0002 0.0009 0.0013 0.0003 0.0011 0.0006 0 0.0026 0.0031 0.0035 0.0001 0 0
Bud Neck 0.0007 0.0002 0.0005 0.001 0.0009 0.0014 0.0017 0.0001 0.0002 0.0003 0.0007 0.0003 0.0103 0.0013 0.0005 0.0002 0.0002 0.0003
Bud Periphery 0.0005 0 0 0.0001 0.0004 0.0001 0.0006 0.0004 0.0002 0.0002 0.0006 0 0.0017 0.003 0.0036 0 0 0
Bud Site 0.0003 0.0001 0.0002 0.0004 0.0002 0.0002 0.006 0.0004 0.001 0.0001 0.0053 0 0.0456 0.0181 0.0048 0.0004 0 0
Cell Periphery 0.0001 0 0 0 0.0001 0 0.0003 0 0.0001 0 0.0001 0 0.0003 0.0006 0.0006 0 0 0
Cytoplasm 0.8807 0.9861 0.9404 0.9075 0.8666 0.9482 0.8958 0.9901 0.9292 0.9396 0.8475 0.9784 0.5839 0.8371 0.8049 0.8358 0.7467 0.9045
Cytoplasmic Foci 0.0125 0.0003 0.0052 0.0031 0.0011 0.0013 0.0152 0.0012 0.0078 0.0008 0.0136 0.0003 0.0165 0.009 0.0041 0.0482 0.0001 0.0006
Eisosomes 0.0001 0 0 0.0001 0.0003 0 0.0001 0 0 0 0.0001 0 0.0002 0 0.0002 0 0 0
Endoplasmic Reticulum 0.0055 0.0005 0.0013 0.0008 0.0044 0.0019 0.0041 0.0002 0.0012 0.0003 0.0047 0.0004 0.0093 0.0003 0.0046 0.0004 0.0001 0.0003
Endosome 0.0111 0.0001 0.0021 0.0007 0.0117 0.0014 0.0126 0.0002 0.0199 0.0029 0.0329 0.0001 0.0533 0.0003 0.002 0.0965 0 0.0002
Golgi 0.0024 0 0.0003 0.0013 0.0053 0.0001 0.0084 0 0.0043 0.0045 0.0225 0 0.0142 0.0006 0.0043 0.0047 0 0
Lipid Particles 0.006 0 0.0008 0.001 0.0013 0 0.0087 0 0.0039 0.0001 0.0252 0 0.0062 0.0001 0.0003 0.001 0 0
Mitochondria 0.001 0 0.0002 0.0002 0.0019 0.0002 0.0016 0.0004 0.0065 0.0251 0.0195 0 0.0194 0.0001 0.0042 0.0004 0.0001 0
None 0.0099 0.0002 0.0036 0.0006 0.0022 0.0004 0.0012 0.0003 0.0006 0.0005 0.0003 0.0002 0.0234 0.0188 0.0165 0.0004 0 0.0003
Nuclear Periphery 0.0079 0.0016 0.0045 0.0016 0.0134 0.0051 0.0025 0.0004 0.0026 0.0014 0.0021 0.0023 0.0449 0.0003 0.0237 0.0007 0.0004 0.0017
Nucleolus 0.0002 0 0.0001 0 0.0001 0.0001 0.0005 0.0002 0.0003 0 0.0004 0 0.0017 0.0004 0.0003 0 0.001 0.0002
Nucleus 0.0409 0.0102 0.0328 0.0149 0.0303 0.0367 0.0144 0.0028 0.009 0.0207 0.0039 0.0175 0.1242 0.0951 0.0817 0.0054 0.2513 0.0913
Peroxisomes 0.0027 0 0.0002 0.0025 0.0004 0 0.0061 0.0001 0.0012 0.0001 0.0116 0 0.0028 0.0009 0.0026 0.0023 0 0
Punctate Nuclear 0.0041 0.0001 0.0052 0.0007 0.0012 0.0008 0.0014 0.0001 0.0009 0.0003 0.001 0.0001 0.0113 0.0003 0.0007 0.0007 0 0.0004
Vacuole 0.0039 0.0001 0.0007 0.0003 0.0005 0.0012 0.0022 0.0011 0.0061 0.0004 0.0021 0.0002 0.0036 0.0008 0.001 0.0018 0 0.0001
Vacuole Periphery 0.0009 0 0.0002 0.0001 0.001 0.0002 0.0004 0.0003 0.0021 0.0004 0.0013 0.0001 0.0043 0.0001 0.0022 0.0006 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 90.7701 95.9137 124.9782 135.4522 114.9052 63.4825 93.8749 100.7988 109.5372 103.4979
Translational Efficiency 1.0292 1.1013 1.0199 1.0949 1.0102 1.0058 0.9412 0.8464 0.9328 0.8549

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1743 1473 2434 1412 704 1631 1565 215 2447 3104 3999 1627

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1721.25 2397.52 2459.96 1759.09 1916.85 2271.23 1701.72 1938.45 1777.52 2331.16 2163.22 1782.79
Standard Deviation 360.17 516.12 441.37 395.20 399.84 545.08 275.62 480.44 382.41 535.26 534.08 411.99
Intensity Change Log 2 — 0.478086 0.515178 0.031373 — 0.244736 -0.171744 0.016166 — 0.359851 0.193981 0.023381

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000081 0.000195 0.000044 0.001373 0.000362 0.000206 0.000295 0.001290 0.000162 0.000201 0.000142 0.001362
Bud Neck 0.000284 0.000368 0.000757 0.005832 0.000795 0.000382 0.002227 0.004968 0.000431 0.000375 0.001332 0.005718
Bud Site 0.000870 0.001075 0.000707 0.017059 0.001710 0.001588 0.006205 0.024344 0.001112 0.001345 0.002859 0.018022
Cell Periphery 0.000061 0.000125 0.000069 0.000169 0.000246 0.000149 0.000106 0.000291 0.000114 0.000137 0.000083 0.000185
Cytoplasm 0.810558* 0.754900* 0.643851* 0.616881* 0.770815* 0.802847* 0.650556* 0.642201* 0.799124* 0.780094* 0.646475* 0.620227*
Cytoplasmic Foci 0.004146 0.004112 0.002376 0.017269 0.007670 0.005686 0.006140 0.080094 0.005160 0.004939 0.003849 0.025571
Eisosomes 0.000001 0.000001 0.000001 0.000014 0.000002 0.000001 0.000004 0.000011 0.000001 0.000001 0.000002 0.000014
Endoplasmic Reticulum 0.000218 0.000244 0.000066 0.000960 0.000546 0.000082 0.000448 0.000254 0.000313 0.000159 0.000215 0.000866
Endosome 0.000141 0.000516 0.000079 0.014940 0.000399 0.000196 0.000912 0.006469 0.000215 0.000348 0.000405 0.013820
Golgi 0.000204 0.001990 0.000094 0.008409 0.001124 0.000695 0.000319 0.000667 0.000469 0.001310 0.000182 0.007386
Lipid Particles 0.000093 0.000248 0.000163 0.003742 0.000571 0.000254 0.000672 0.004198 0.000231 0.000251 0.000362 0.003802
Mitochondria 0.000155 0.000165 0.000249 0.004750 0.000278 0.000377 0.000370 0.000125 0.000190 0.000277 0.000296 0.004138
Mitotic Spindle 0.001253 0.002582 0.003171 0.073848 0.002751 0.001271 0.026863 0.052688 0.001684 0.001893 0.012443 0.071052
None 0.014331 0.013763 0.013217 0.005121 0.010198 0.016243 0.008891 0.005020 0.013142 0.015066 0.011524 0.005107
Nuclear Periphery 0.000083 0.000131 0.000372 0.001011 0.000159 0.000055 0.000600 0.000365 0.000105 0.000091 0.000461 0.000925
Nuclear Periphery Foci 0.001358 0.001582 0.000419 0.005736 0.004567 0.001911 0.002541 0.003959 0.002281 0.001755 0.001249 0.005501
Nucleolus 0.000079 0.000073 0.000148 0.000979 0.000103 0.000104 0.000283 0.000187 0.000086 0.000089 0.000201 0.000875
Nucleus 0.160827* 0.214168* 0.329032* 0.120160 0.190375* 0.163974* 0.261963* 0.073508 0.169328* 0.187793* 0.302785* 0.113995
Peroxisomes 0.000012 0.000021 0.000013 0.001868 0.000021 0.000051 0.000684 0.017220 0.000015 0.000037 0.000276 0.003897
Vacuole 0.005030 0.002776 0.005120 0.086928 0.006412 0.003609 0.029705 0.081992 0.005428 0.003214 0.014741 0.086276
Vacuole Periphery 0.000215 0.000965 0.000054 0.012951 0.000895 0.000318 0.000217 0.000150 0.000411 0.000625 0.000118 0.011260

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.70 -0.77 -4.49 -3.09 -4.42 2.09 -0.24 -1.84 -2.75 -1.81 -0.82 -1.68 -4.31 -3.77 -3.90
Bud Neck -1.68 -14.13 -12.09 -11.67 -7.10 3.33 -7.51 -7.56 -8.41 -4.21 0.70 -14.69 -13.37 -13.57 -6.87
Bud Site -0.71 -1.91 -10.29 -10.09 -9.92 0.33 -5.29 -5.62 -5.65 -4.25 -1.18 -5.96 -11.51 -11.15 -9.33
Cell Periphery -5.07 -6.26 -7.87 -1.66 -2.49 2.90 3.33 -2.49 -4.57 -4.84 -2.06 -2.51 -5.23 -2.60 -3.80
Cytoplasm 9.54 40.28 25.56 17.59 -3.19 -4.07 22.81 13.18 15.24 3.78 4.52 46.89 27.59 25.40 -1.99
Cytoplasmic Foci -0.29 0.31 -10.75 -9.88 -11.13 1.35 0.39 -5.58 -5.87 -5.70 -0.62 -0.47 -10.87 -10.35 -10.92
Eisosomes -0.45 -6.40 -13.39 -11.20 -11.98 2.42 -11.79 -7.00 -7.79 -3.14 0.54 -14.87 -14.50 -14.11 -9.40
Endoplasmic Reticulum -0.07 2.48 -2.04 -0.89 -4.66 3.89 0.27 2.13 -4.15 3.27 2.10 0.88 -0.42 -2.48 -1.45
Endosome -2.10 -0.92 -5.08 -4.49 -5.04 2.56 -3.64 -3.35 -3.73 -2.72 -1.21 -4.66 -5.43 -5.22 -5.08
Golgi -2.81 1.56 -3.04 0.09 -3.13 1.83 4.56 3.38 1.40 -4.24 -2.61 4.56 -2.48 -0.66 -3.13
Lipid Particles -3.79 -11.35 -8.08 -7.55 -6.94 3.05 -5.12 -6.74 -7.19 -5.97 -0.73 -11.44 -9.59 -9.50 -7.85
Mitochondria -0.15 -3.02 -2.28 -2.28 -1.73 -0.26 -1.60 1.35 0.83 8.47 -0.53 -3.47 -2.18 -1.91 -1.60
Mitotic Spindle -1.16 -6.33 -9.30 -8.85 -7.72 1.38 -6.69 -4.62 -4.79 -3.09 -0.04 -9.21 -10.29 -10.28 -7.17
None 0.59 2.10 10.59 10.72 18.59 -4.48 1.14 4.58 12.94 6.72 -2.06 2.95 11.31 17.67 18.55
Nuclear Periphery -0.89 -15.46 -9.96 -7.38 0.83 3.80 -20.08 -10.48 -12.50 1.67 0.55 -24.69 -11.42 -10.90 2.53
Nuclear Periphery Foci -1.05 3.88 -3.49 -2.69 -5.05 3.88 3.28 -0.95 -3.98 -3.51 1.47 3.80 -2.21 -3.16 -4.49
Nucleolus 0.51 -5.79 -3.04 -3.07 -1.82 -0.34 -2.43 -4.17 -3.07 1.15 -0.55 -4.70 -3.13 -3.03 -1.44
Nucleus -9.92 -37.70 6.48 15.33 42.03 3.48 -12.27 10.60 9.48 22.16 -4.84 -37.30 10.18 15.07 44.77
Peroxisomes -1.14 -1.13 -4.29 -4.24 -4.25 -1.20 -2.25 -1.86 -1.84 -1.67 -1.58 -2.34 -3.89 -3.78 -3.33
Vacuole 3.85 -11.86 -28.21 -28.82 -24.20 2.86 -21.85 -14.71 -14.91 -9.89 4.01 -23.98 -31.43 -31.98 -22.73
Vacuole Periphery -1.69 1.30 -2.94 -1.91 -3.11 1.52 2.05 2.05 1.22 -0.04 -0.79 2.37 -2.64 -2.33 -3.09
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Arginine/alanine amino peptidase; overproduction stimulates glycogen accumulation; AAP1 has a paralog, APE2, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (97%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Aap1

Aap1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aap1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available