Standard name
Human Ortholog
Description Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.05 0.05 0 0.06 0.06 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.86 0.9 0.96 0.92 0.85 0.74 0.74 0.77 0.84 0.85 0.87 0.88 0.81 0.86 0.86 0.51 0.51 0.54 0.17 0.29 0.27 0.13 0.19 0.17
Endoplasmic Reticulum 0 0.09 0 0 0.08 0.12 0.08 0 0 0 0 0 0.14 0.06 0.05 0 0 0 0.19 0.34 0.34 0.07 0 0.05
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0.08 0.12 0.2 0.21 0.19 0.19 0.15 0.17 0 0 0 0 0 0 0 0 0.07 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.16 0.1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.12 0 0 0 0 0 0 0 0 0.06 0.06 0 0 0.07 0.06 0.57 0.48 0.46 0.49 0.25 0.25 0.61 0.64 0.65
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 0 0 1 8 4 3 1 0 1 2 2 2 2 0 1 0 1 2 1 2 1 1
Bud 0 1 2 2 15 19 20 33 25 22 23 18 3 2 0 0 0 0 2 5 3 2 4 2
Bud Neck 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 3 8 1 1 0 0
Bud Site 0 0 0 0 0 2 1 1 0 2 3 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 0 1 6 11 8 1 3 5 1 5 0 0 2 0 0 1 0 1 0 0 0 0
Cytoplasm 179 327 204 200 240 275 341 450 374 411 349 440 218 237 282 121 81 82 42 116 59 23 57 47
Endoplasmic Reticulum 8 33 2 8 22 43 35 14 6 2 3 4 39 17 17 4 2 3 47 138 74 13 11 15
Endosome 2 0 3 1 1 4 1 1 3 0 0 1 2 8 8 2 4 3 7 12 4 12 11 6
Golgi 1 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 3 1 0 1 5 3
Mitochondria 4 1 6 12 22 46 93 124 84 91 60 86 0 0 0 2 3 0 9 12 14 6 6 11
Nucleus 0 0 0 0 1 0 6 11 0 5 4 3 1 1 5 26 26 15 0 0 0 0 0 0
Nuclear Periphery 0 1 0 0 0 1 1 8 0 1 1 0 0 0 0 0 0 2 1 1 0 0 2 1
Nucleolus 0 0 0 0 0 0 1 3 1 0 2 0 0 0 0 0 0 0 0 0 0 0 1 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0
SpindlePole 0 0 1 0 0 1 0 0 0 2 0 2 1 1 2 0 1 0 1 1 0 1 2 2
Vac/Vac Membrane 25 6 1 2 4 7 9 20 16 29 23 20 11 19 21 134 77 69 120 101 54 108 200 182
Unique Cell Count 208 365 213 217 282 370 459 586 446 483 402 499 270 274 327 237 159 151 245 408 222 179 312 281
Labelled Cell Count 220 373 219 226 312 417 521 669 514 570 470 582 277 288 340 289 195 175 245 408 222 179 312 281


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.7 6.0 4.3 4.6 5.0 5.0 4.5 4.7 4.3 3.9 4.1 3.9 6.7 6.2 6.3 7.4 7.1 7.9 6.9 7.0 6.9
Std Deviation (1e-4) 0.9 1.0 0.9 1.3 1.7 1.2 1.3 1.4 1.1 1.0 1.2 1.1 1.1 1.0 1.0 1.9 1.5 1.7 1.6 1.9 1.6
Intensity Change (Log2) – – – 0.09 0.22 0.22 0.09 0.14 0.0 -0.14 -0.06 -0.14 0.66 0.54 0.56 0.79 0.74 0.89 0.69 0.72 0.69

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 2.6 2.6 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.6 -3.9 -6.5 -6.6 -6.2 -4.4 -4.0 -3.5 -3.2 -4.9 -3.5 -3.6 -10.6 -10.1 -9.5
Endoplasmic Reticulum 0 3.5 4.7 0 0 0 0 0 0 5.3 3.0 2.6 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 2.4 3.9 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 5.0 6.1 4.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.3 2.4 3.3 3.2 2.6 2.5 3.6 3.4 13.0 11.2 10.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.8639 2.7856 3.0581 2.6709 2.4365 2.2097 3.1263 4.2308 4.1835 3.8877 3.4718 3.6904 0.1362 1.8779 1.5602 1.1444 1.2969 0.8587
Actin 0.015 0.0002 0.0072 0.0085 0.009 0.0007 0.0081 0.0002 0.0025 0.0001 0.0177 0.0015 0.0004 0.0001 0.0001 0 0 0
Bud 0.0004 0.0006 0.0057 0.0006 0.0022 0.0006 0.0007 0.0006 0.0004 0.0003 0.0017 0.0003 0.0002 0.0033 0.0002 0.0001 0.0001 0.0001
Bud Neck 0.0009 0.0004 0.0065 0.0011 0.0008 0.0014 0.0067 0.0003 0.0008 0.0006 0.0012 0.0031 0.0002 0.0003 0.0034 0.0039 0.0005 0.0006
Bud Periphery 0.0005 0.0006 0.0029 0.0006 0.0029 0.0008 0.0012 0.0008 0.0004 0.0005 0.0015 0.0004 0.0003 0.0034 0.0002 0.0002 0.0002 0.0001
Bud Site 0.0015 0.0037 0.0056 0.0016 0.0054 0.0003 0.0074 0.0029 0.0056 0.0004 0.0028 0.0006 0.0007 0.0104 0.0013 0.0005 0.0002 0.0001
Cell Periphery 0.0004 0.0007 0.0005 0.0003 0.0002 0.0002 0.001 0.0008 0.001 0.0005 0.0006 0.0003 0.0006 0.0006 0.0005 0.0003 0.0001 0.0002
Cytoplasm 0.3915 0.51 0.471 0.3422 0.4782 0.5086 0.3101 0.5347 0.4112 0.2511 0.3426 0.4588 0.3618 0.4327 0.4635 0.3061 0.5903 0.3848
Cytoplasmic Foci 0.0451 0.0444 0.0452 0.0308 0.0327 0.046 0.0569 0.0333 0.0369 0.0233 0.0522 0.0481 0.0303 0.032 0.0302 0.0543 0.0187 0.0365
Eisosomes 0.0001 0 0.0001 0.0001 0.0002 0 0.0004 0 0 0 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.07 0.0687 0.1122 0.1373 0.0264 0.0501 0.1012 0.1059 0.1261 0.1259 0.0828 0.0838 0.1071 0.143 0.1467 0.0951 0.0856 0.0847
Endosome 0.159 0.1241 0.1532 0.2337 0.1545 0.1378 0.1649 0.103 0.1513 0.2338 0.1902 0.156 0.1817 0.1226 0.1572 0.1959 0.1319 0.193
Golgi 0.0081 0.0031 0.0061 0.0061 0.0111 0.0023 0.0098 0.0023 0.0097 0.0055 0.0272 0.0064 0.0053 0.0016 0.0043 0.0013 0.0006 0.0014
Lipid Particles 0.0186 0.0035 0.007 0.0074 0.0168 0.0087 0.0223 0.0041 0.0098 0.0017 0.0267 0.0163 0.0116 0.0045 0.0075 0.003 0.0006 0.002
Mitochondria 0.0048 0.002 0.0063 0.0035 0.0524 0.0039 0.0093 0.0015 0.0078 0.0045 0.0119 0.0041 0.0065 0.001 0.0107 0.0005 0.0004 0.0011
None 0.1723 0.1218 0.0793 0.1136 0.0492 0.1114 0.1717 0.0932 0.1109 0.0051 0.0449 0.0834 0.1499 0.0874 0.0667 0.072 0.0147 0.0628
Nuclear Periphery 0.0193 0.0156 0.015 0.0364 0.0209 0.0133 0.0129 0.0136 0.0132 0.0143 0.0187 0.0125 0.0161 0.0183 0.0142 0.0166 0.0118 0.0149
Nucleolus 0.0005 0.0007 0.0005 0.0004 0.001 0.0005 0.0015 0.0003 0.0005 0.0001 0.0007 0.0012 0.0004 0.001 0.0011 0.0005 0.0001 0.0003
Nucleus 0.0073 0.0101 0.006 0.005 0.0135 0.0103 0.0042 0.005 0.0039 0.0037 0.0065 0.0064 0.0043 0.0055 0.0038 0.0066 0.0053 0.009
Peroxisomes 0.0146 0.0011 0.0021 0.0016 0.0061 0.0131 0.0062 0.0003 0.0077 0.0001 0.0242 0.0016 0.0012 0.0004 0.001 0.0001 0.0001 0.0001
Punctate Nuclear 0.0041 0.0017 0.0036 0.0037 0.0215 0.0039 0.0071 0.0007 0.001 0.0003 0.0052 0.0022 0.001 0.0022 0.0007 0.0013 0.0004 0.0006
Vacuole 0.06 0.0813 0.0574 0.0555 0.0827 0.0767 0.0904 0.0902 0.0919 0.28 0.1288 0.1029 0.1119 0.1228 0.08 0.2263 0.1266 0.1877
Vacuole Periphery 0.0057 0.0056 0.0066 0.0099 0.0123 0.0095 0.0059 0.0062 0.0075 0.0483 0.0116 0.0102 0.0085 0.0068 0.0066 0.0154 0.0119 0.02

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 99.2891 44.7651 13.7452 38.008 97.3891 84.5648 39.7993 38.976 39.0407 78.8593
Translational Efficiency 0.6373 0.5466 0.8284 0.5747 0.4852 0.8091 0.6324 0.3864 0.6333 0.6277

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1284 1907 1688 1338 870 1981 1045 1803 2154 3888 2733 3141

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 618.79 812.68 939.62 1011.26 720.28 731.09 1003.53 1049.26 659.78 771.11 964.06 1033.07
Standard Deviation 72.98 110.69 129.60 143.99 90.27 102.28 125.60 141.35 94.58 114.03 131.80 143.72
Intensity Change Log 2 — 0.393238 0.602628 0.708632 — 0.021491 0.478454 0.542742 — 0.205226 0.537166 0.621777

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000220 0.000338 0.000317 0.002375 0.000077 0.000293 0.000748 0.003509 0.000162 0.000315 0.000482 0.003026
Bud Neck 0.034914 0.011565 0.005200 0.011344 0.011578 0.021678 0.004451 0.010773 0.025489 0.016718 0.004914 0.011016
Bud Site 0.007949 0.008549 0.008181 0.034669 0.002575 0.009483 0.007793 0.023750 0.005778 0.009025 0.008032 0.028401
Cell Periphery 0.000511 0.000104 0.000293 0.000845 0.000240 0.000161 0.000605 0.001095 0.000402 0.000133 0.000412 0.000988
Cytoplasm 0.306632 0.323144 0.382947 0.292005 0.296222 0.276662 0.329590 0.316646 0.302427 0.299461 0.362545 0.306150
Cytoplasmic Foci 0.304811 0.207366 0.042897 0.057945 0.254565 0.221510 0.040116 0.073846 0.284516 0.214573 0.041834 0.067073
Eisosomes 0.000821 0.000117 0.000077 0.000309 0.000227 0.000229 0.000175 0.000492 0.000581 0.000174 0.000115 0.000414
Endoplasmic Reticulum 0.021374 0.016389 0.109308 0.113897 0.014182 0.021266 0.246564 0.191781 0.018469 0.018874 0.161790 0.158604
Endosome 0.069400 0.064899 0.017735 0.020896 0.098064 0.080233 0.011020 0.021757 0.080978 0.072712 0.015167 0.021390
Golgi 0.023325 0.004670 0.000344 0.002476 0.003261 0.007800 0.001433 0.005055 0.015221 0.006265 0.000761 0.003956
Lipid Particles 0.047974 0.017312 0.017046 0.028676 0.027983 0.033249 0.021843 0.044541 0.039900 0.025432 0.018880 0.037783
Mitochondria 0.013774 0.002232 0.000649 0.002394 0.001014 0.005516 0.000514 0.002831 0.008620 0.003905 0.000597 0.002645
Mitotic Spindle 0.000053 0.001885 0.003027 0.019709 0.000091 0.000873 0.000870 0.005806 0.000068 0.001370 0.002202 0.011729
None 0.003298 0.000968 0.001671 0.001625 0.000874 0.001108 0.000675 0.000733 0.002319 0.001039 0.001290 0.001113
Nuclear Periphery 0.000531 0.001066 0.033543 0.007446 0.001886 0.001788 0.016193 0.002937 0.001078 0.001434 0.026909 0.004858
Nuclear Periphery Foci 0.000383 0.001990 0.048679 0.030836 0.001448 0.001725 0.068986 0.023927 0.000813 0.001855 0.056444 0.026870
Nucleolus 0.000561 0.001313 0.000879 0.000512 0.000721 0.001227 0.000249 0.000428 0.000625 0.001269 0.000638 0.000464
Nucleus 0.030055 0.037068 0.153348 0.061043 0.039334 0.039027 0.113247 0.057554 0.033803 0.038066 0.138015 0.059040
Peroxisomes 0.007614 0.003725 0.000695 0.001874 0.003038 0.005479 0.001007 0.002629 0.005766 0.004619 0.000814 0.002307
Vacuole 0.117322 0.290799 0.172483 0.306615 0.239438 0.265194 0.133658 0.208064 0.166644 0.277752 0.157638 0.250045
Vacuole Periphery 0.008477 0.004501 0.000680 0.002508 0.003181 0.005499 0.000265 0.001846 0.006338 0.005010 0.000521 0.002128

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.12 -2.72 -5.24 -4.80 -4.90 -5.80 -8.50 -7.14 -6.67 -5.31 -2.81 -8.41 -8.74 -8.17 -7.45
Bud Neck 9.71 12.41 9.94 0.54 -6.00 -5.52 4.25 0.25 7.62 -6.46 5.31 12.89 9.00 6.44 -8.54
Bud Site -0.43 -0.39 -8.11 -7.89 -7.56 -8.23 -3.73 -11.72 -7.30 -6.52 -4.29 -2.58 -13.00 -10.79 -10.16
Cell Periphery 12.89 6.62 -1.85 -6.49 -4.36 2.59 -7.33 -7.72 -8.88 -3.77 11.80 -0.65 -6.74 -11.04 -6.59
Cytoplasm -2.06 -7.29 2.02 4.00 8.83 2.08 -2.57 -1.94 -4.80 0.97 0.35 -7.39 -0.15 -0.53 7.44
Cytoplasmic Foci 14.59 46.34 42.71 32.27 -4.04 4.66 34.62 28.78 31.77 -10.36 14.29 57.39 50.23 44.62 -10.94
Eisosomes 13.65 15.13 9.71 -4.00 -5.66 -0.11 2.34 -7.40 -7.41 -8.51 12.82 15.02 5.44 -8.48 -11.39
Endoplasmic Reticulum 2.02 -16.52 -11.15 -12.48 2.43 -2.50 -24.17 -23.25 -22.74 5.10 -0.06 -28.17 -25.03 -25.63 2.28
Endosome 1.70 20.27 19.30 19.74 -0.70 3.51 19.34 16.77 22.74 -8.84 3.09 27.54 24.88 29.83 -5.64
Golgi 13.29 16.93 15.07 4.67 -3.31 -5.49 2.61 -1.76 3.74 -4.04 9.61 16.37 12.71 5.26 -6.22
Lipid Particles 12.57 13.19 7.95 -4.59 -5.16 -2.44 3.15 -6.33 -4.66 -10.42 8.39 13.01 1.97 -7.11 -12.57
Mitochondria 11.56 13.31 10.89 0.71 -2.41 -8.29 3.35 -2.68 3.70 -3.52 7.11 13.25 8.85 3.32 -4.22
Mitotic Spindle -3.13 -4.44 -7.80 -6.99 -6.39 -3.04 -3.58 -5.01 -4.20 -4.09 -4.14 -5.09 -9.21 -8.03 -7.04
None 2.48 1.80 1.91 -0.87 0.52 -0.62 0.79 0.56 1.26 -0.27 2.18 1.88 2.24 0.22 1.12
Nuclear Periphery -3.77 -16.41 -6.98 -6.32 11.97 0.14 -10.25 -1.69 -2.61 10.32 -1.16 -18.93 -7.50 -6.96 15.78
Nuclear Periphery Foci -9.40 -22.74 -15.52 -14.53 7.35 -1.11 -21.77 -17.63 -17.03 13.42 -6.42 -31.29 -23.58 -22.30 14.80
Nucleolus -3.07 -2.09 0.08 3.08 2.10 -4.00 7.25 4.00 6.57 -4.61 -4.76 -0.20 3.04 5.75 1.50
Nucleus -4.14 -28.40 -10.77 -8.06 19.68 0.19 -16.45 -6.68 -8.19 12.40 -2.92 -32.44 -13.18 -11.59 23.54
Peroxisomes 7.50 14.61 12.01 6.40 -3.72 -5.14 5.07 1.11 5.14 -2.98 2.95 15.13 9.54 7.12 -4.62
Vacuole -25.82 -10.89 -27.21 -7.31 -18.77 -3.06 9.75 1.15 4.93 -9.89 -20.73 -1.63 -19.26 -1.09 -18.52
Vacuole Periphery 7.63 15.89 9.13 4.34 -2.22 -6.92 15.03 4.23 9.38 -4.64 3.98 18.87 10.95 9.45 -4.27
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport
Localization
Cell Percentages ER (12%), cytoplasm (11%), mixed (34%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Erp5

Erp5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Erp5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available