Standard name
Human Ortholog
Description Mitochondrial outer membrane protein; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; TOM71 has a paralog, TOM70, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.08 0.14 0 0 0 0 0 0
Cytoplasm 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0.15 0.13 0.23 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0.05 0 0
Golgi 0 0.05 0.09 0 0 0 0 0 0 0 0 0.39 0.49 0.5 0.13 0.23 0.19 0.05 0.08 0.05 0.06 0.14 0.16
Mitochondria 0.94 0.91 0.88 0.88 0.86 0.9 0.89 0.88 0.95 0.95 0.93 0.66 0.6 0.47 0.08 0.07 0.08 0.74 0.78 0.85 0.83 0.59 0.67
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.06 0 0 0 0 0.08 0.1 0.06 0.06 0.06 0.07 0 0 0 0.06 0.07 0.05 0 0 0 0 0 0
Nucleolus 0.15 0.05 0.05 0 0.1 0.13 0.16 0.13 0.11 0.1 0.1 0 0 0.05 0.05 0 0.05 0 0 0 0 0 0
Peroxisomes 0 0 0.06 0.05 0 0 0 0 0 0 0 0 0 0 0.12 0.1 0.07 0 0 0 0 0.06 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.15 0.11 0.07 0 0.06 0 0 0 0 0 0 0.26 0.19 0.28 0.21 0.25 0.22 0.09 0.06 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 4 2 0 0 0 0 1 0 0 0 1 3 0 2 5 1 0 6 6 0 2 1
Bud 0 3 2 12 0 7 6 12 12 11 14 1 0 0 8 6 0 0 3 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 1 0 8 2 2 4 13 4 0 0 0 3 2 0
Cell Periphery 0 12 12 5 2 2 1 1 2 5 2 1 2 1 18 13 14 0 0 1 0 0 0
Cytoplasm 0 5 5 17 6 7 6 11 4 4 5 1 2 2 24 20 23 0 0 0 0 0 0
Endoplasmic Reticulum 0 7 3 1 0 1 2 1 4 1 4 3 4 1 3 12 9 0 1 0 0 0 0
Endosome 0 5 13 6 7 5 3 6 0 1 1 2 3 5 8 7 4 1 8 7 1 1 0
Golgi 0 17 35 1 3 0 0 0 0 0 0 50 73 61 20 36 19 2 28 19 1 7 7
Mitochondria 32 318 355 243 192 364 364 429 380 440 397 84 90 58 12 11 8 44 289 372 26 30 32
Nucleus 0 0 2 1 0 5 2 4 1 2 1 0 0 0 5 4 1 0 0 0 0 1 0
Nuclear Periphery 2 6 14 4 8 34 39 30 25 30 31 1 5 0 9 11 5 0 0 0 0 0 0
Nucleolus 5 17 20 10 22 53 64 62 44 46 41 5 2 6 7 7 5 0 0 0 0 0 0
Peroxisomes 0 3 25 14 4 4 1 7 0 4 8 0 1 0 18 16 7 0 3 18 0 3 1
SpindlePole 0 0 7 3 2 4 2 10 4 4 4 0 0 0 9 2 3 2 1 2 0 1 0
Vac/Vac Membrane 5 38 30 10 14 18 15 12 15 10 13 33 29 34 32 39 22 5 23 2 1 1 2
Unique Cell Count 34 351 403 277 224 405 407 486 398 462 425 127 150 123 155 159 102 60 371 440 32 52 49
Labelled Cell Count 44 435 525 328 260 512 507 588 495 571 525 182 214 168 178 191 121 60 371 440 32 52 49


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.2 11.0 9.9 9.1 8.7 7.2 6.9 6.6 5.8 5.9 5.7 11.5 10.9 11.7 7.8 8.7 9.2
Std Deviation (1e-4) 2.1 2.8 2.1 2.1 2.1 1.9 1.7 1.7 1.5 1.4 1.5 2.1 1.5 1.8 1.8 1.9 2.3
Intensity Change (Log2) -0.13 -0.19 -0.46 -0.53 -0.58 -0.77 -0.75 -0.8 0.22 0.14 0.24 -0.34 -0.19 -0.11

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT10510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 3.5 0 0 0 2.4 2.7 2.3 2.9 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 3.4 0 0 0 0 0 0 0
Cell Periphery -1.0 -1.7 -2.7 -3.1 -3.4 -2.7 -2.0 -2.8 0 0 0 4.1 2.7 4.4
Cytoplasm 3.5 0 0.6 0.3 1.1 0 0 0 0 0 0 6.8 5.9 8.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome -0.8 -0.1 -1.9 -2.5 -2.0 -3.6 -3.5 -3.3 0 0 0 1.1 0.7 0
Golgi -4.8 -3.7 -6.1 -6.1 -6.6 -6.0 -6.5 -6.2 8.2 10.5 10.3 1.5 4.5 2.9
Mitochondria -0.1 -0.9 0.8 0.6 0.1 3.8 3.8 2.7 -5.7 -7.4 -9.7 -17.9 -18.2 -16.1
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.6 0.1 3.0 3.5 1.8 1.8 2.0 2.4 0 -0.1 0 1.2 1.8 0
Nucleolus -0.8 2.3 4.0 5.0 4.0 3.2 2.8 2.6 -0.5 -1.9 0 -0.2 -0.3 0
Peroxisomes -0.6 -2.5 -4.0 -4.8 -3.8 -5.0 -4.4 -3.2 -2.9 -2.7 -2.8 2.1 1.6 0.2
SpindlePole 0 0 -0.9 0 0.3 -0.9 -1.1 -1.0 0 0 0 0 0 0
Vacuole -2.1 -0.6 -1.8 -2.3 -3.5 -2.3 -3.7 -2.8 5.6 4.0 6.0 4.4 5.6 4.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 8.4205 10.1701 9.6297 9.1266 9.2702 9.6709 9.6895 11.4649 10.8356 11.4591 9.6177 10.7564 12.3982 13.7994 12.783 15.1285 11.9092 13.5379
Actin 0.0234 0.0078 0.007 0.0244 0.0072 0.0018 0.0049 0.0089 0.003 0 0.0234 0.0014 0.0065 0.0133 0.0123 0.0046 0.0023 0.0109
Bud 0.0008 0.0031 0.0012 0.0004 0.0004 0.0005 0.0002 0.0002 0.0002 0 0.0007 0 0.0046 0.0159 0.0295 0.0039 0.0081 0.0024
Bud Neck 0.0047 0.0004 0.0004 0.0001 0.0002 0.0003 0.0031 0.0001 0.0001 0 0.0001 0 0.0012 0.0005 0.0003 0.0002 0.0001 0.0524
Bud Periphery 0.0014 0.0029 0.0039 0.0008 0.001 0.0021 0.0004 0.0004 0.0009 0 0.0017 0.0001 0.0207 0.0316 0.0623 0.0199 0.013 0.0055
Bud Site 0.0132 0.0119 0.0034 0.0006 0.0007 0.0007 0.0029 0.0024 0.0004 0 0.0007 0.0001 0.0141 0.0507 0.0124 0.0006 0.0004 0.0016
Cell Periphery 0.0012 0.0015 0.0019 0.0003 0.0003 0.0018 0.0002 0.0002 0.0003 0 0.0002 0.0001 0.0088 0.0022 0.0031 0.0014 0.0005 0.0024
Cytoplasm 0.0087 0.0015 0.0099 0.0004 0.0009 0.0002 0.0003 0.0003 0 0 0.0001 0.0001 0.0915 0.0823 0.0687 0.0548 0.1337 0.0877
Cytoplasmic Foci 0.0142 0.0078 0.005 0.0028 0.005 0.0031 0.0103 0.003 0.0005 0 0.0022 0.0012 0.0198 0.0095 0.0132 0.0066 0.0147 0.0227
Eisosomes 0.0005 0.0004 0.0002 0.0001 0.0002 0.0002 0.0003 0.0002 0.0001 0 0.0002 0.0001 0.0006 0.0003 0.0004 0.0022 0.0003 0.0003
Endoplasmic Reticulum 0.0033 0.0007 0.0006 0.0005 0.0023 0.0002 0.0008 0.0002 0.0001 0 0.0002 0.0003 0.0231 0.001 0.0214 0.007 0.0365 0.0296
Endosome 0.0326 0.0122 0.0093 0.0156 0.0591 0.0229 0.0222 0.0059 0.0017 0.0001 0.0048 0.0039 0.017 0.0055 0.0084 0.0097 0.0025 0.0091
Golgi 0.0154 0.0149 0.0046 0.0056 0.011 0.0338 0.0261 0.0094 0.0022 0.0003 0.013 0.0084 0.0128 0.0076 0.0049 0.0019 0.0009 0.0108
Lipid Particles 0.0229 0.0045 0.0018 0.0016 0.0084 0.0026 0.0263 0.0025 0.0041 0.0005 0.0175 0.0037 0.0125 0.0051 0.0074 0.0029 0.0017 0.0031
Mitochondria 0.7755 0.8848 0.9387 0.9167 0.8511 0.9177 0.856 0.9571 0.9786 0.9979 0.9125 0.974 0.6798 0.6867 0.701 0.7494 0.6726 0.6876
None 0.0015 0.0005 0.0002 0.0001 0.0008 0.0001 0.0002 0.0003 0 0 0.0001 0.0001 0.045 0.052 0.0288 0.0735 0.0999 0.0402
Nuclear Periphery 0.0194 0.0009 0.0006 0.0008 0.0114 0.0002 0.0018 0.0001 0.0001 0 0.0002 0.0002 0.002 0.0006 0.002 0.002 0.0014 0.0043
Nucleolus 0.0019 0.0011 0.0001 0.0005 0.0006 0.0002 0.0005 0.0001 0.0002 0 0.0003 0.0009 0.0038 0.0007 0.0014 0.0002 0.0007 0.0005
Nucleus 0.019 0.0009 0.0015 0.0003 0.0024 0.0002 0.0003 0.0001 0.0001 0 0.0002 0.0004 0.0017 0.0009 0.0012 0.0007 0.001 0.0015
Peroxisomes 0.01 0.0037 0.0019 0.0056 0.0046 0.0015 0.0332 0.0028 0.0028 0.0004 0.0081 0.0014 0.0073 0.0144 0.0031 0.0145 0.0019 0.0058
Punctate Nuclear 0.003 0.0004 0.0006 0.0001 0.001 0.0007 0.0012 0.0003 0 0 0 0.0001 0.0029 0.0005 0.0015 0.0003 0.004 0.0054
Vacuole 0.0116 0.0168 0.0039 0.009 0.0103 0.0036 0.0021 0.0015 0.002 0.0001 0.0043 0.0008 0.0149 0.0075 0.0107 0.0297 0.002 0.0066
Vacuole Periphery 0.0158 0.0213 0.0034 0.0134 0.0209 0.0055 0.0065 0.0041 0.0026 0.0005 0.0095 0.0026 0.0093 0.0112 0.0058 0.0138 0.0017 0.0098

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 35.3434 36.4754 36.9779 39.1362 45.8243 33.3136 40.6461 40.6681 42.9143 44.8524
Translational Efficiency 0.9283 0.7697 0.77 0.9049 0.7275 0.853 0.6945 0.8646 0.7976 0.7641

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
131 960 209 1364 1683 1344 1687 1243 1814 2304 1896 2607

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1187.34 1006.72 1428.89 1252.07 948.30 1099.33 1338.49 1283.24 965.56 1060.74 1348.45 1266.93
Standard Deviation 162.29 185.20 197.37 224.98 151.06 184.36 217.66 214.51 164.02 190.27 217.37 220.60
Intensity Change Log 2 -0.238071 0.267162 0.076582 0.213209 0.497191 0.436376 -0.020129 0.373852 0.247494

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.053723 0.002860 0.003112 0.007192 0.000659 0.001136 0.002914 0.004788 0.004492 0.001854 0.002936 0.006046
Bud Neck 0.005504 0.001523 0.016551 0.001758 0.000863 0.000837 0.002527 0.001909 0.001198 0.001123 0.004072 0.001830
Bud Site 0.104395 0.003891 0.015532 0.012211 0.001678 0.001760 0.007143 0.010440 0.009095 0.002648 0.008068 0.011367
Cell Periphery 0.009960 0.000352 0.000357 0.001184 0.000281 0.000147 0.000705 0.000687 0.000980 0.000232 0.000666 0.000947
Cytoplasm 0.008192 0.001699 0.000912 0.001159 0.000218 0.000289 0.000733 0.000940 0.000794 0.000876 0.000753 0.001055
Cytoplasmic Foci 0.048338 0.013577 0.055040 0.009229 0.005660 0.007992 0.005984 0.012381 0.008742 0.010319 0.011391 0.010732
Eisosomes 0.000375 0.000139 0.000168 0.000171 0.000052 0.000057 0.000092 0.000117 0.000075 0.000091 0.000100 0.000145
Endoplasmic Reticulum 0.011235 0.000286 0.000815 0.000659 0.000173 0.000174 0.001536 0.000808 0.000972 0.000221 0.001456 0.000730
Endosome 0.062593 0.014362 0.036818 0.010804 0.008630 0.010515 0.006659 0.017133 0.012527 0.012118 0.009983 0.013821
Golgi 0.231836 0.024202 0.041192 0.052259 0.011674 0.019350 0.029377 0.078519 0.027573 0.021372 0.030679 0.064780
Lipid Particles 0.001608 0.003929 0.008697 0.000610 0.002162 0.001343 0.000516 0.000710 0.002122 0.002420 0.001418 0.000657
Mitochondria 0.261287 0.905239 0.595490 0.850415 0.944475 0.932103 0.884479 0.807230 0.895138 0.920910 0.852623 0.829825
Mitotic Spindle 0.011231 0.001031 0.028043 0.007435 0.001413 0.000930 0.004669 0.008530 0.002122 0.000972 0.007246 0.007957
None 0.000385 0.000646 0.001454 0.000980 0.000547 0.000536 0.001088 0.000851 0.000535 0.000582 0.001128 0.000918
Nuclear Periphery 0.000597 0.000088 0.006652 0.000256 0.000211 0.000113 0.000291 0.000328 0.000239 0.000103 0.000993 0.000290
Nuclear Periphery Foci 0.000656 0.000281 0.005027 0.000213 0.000280 0.000133 0.000347 0.000304 0.000307 0.000195 0.000863 0.000256
Nucleolus 0.000097 0.000150 0.005593 0.000143 0.000666 0.000642 0.000906 0.000180 0.000625 0.000437 0.001423 0.000161
Nucleus 0.000488 0.000166 0.002941 0.000070 0.000227 0.000326 0.000327 0.000124 0.000246 0.000259 0.000615 0.000096
Peroxisomes 0.010955 0.012122 0.015984 0.004881 0.007930 0.003325 0.004190 0.006148 0.008148 0.006990 0.005490 0.005485
Vacuole 0.089176 0.005996 0.076087 0.012690 0.005327 0.008267 0.016141 0.018868 0.011383 0.007321 0.022749 0.015636
Vacuole Periphery 0.087368 0.007462 0.083535 0.025683 0.006876 0.010024 0.029377 0.029006 0.012688 0.008957 0.035347 0.027267

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.70 3.69 3.38 -3.15 -3.01 -1.20 -3.97 -3.45 -2.94 -1.42 2.35 1.29 -1.22 -4.57 -3.16
Bud Neck 4.07 -3.65 3.91 -0.67 5.33 0.09 -3.37 -2.65 -2.74 0.97 0.36 -5.16 -2.17 -2.80 4.03
Bud Site 6.52 5.57 5.97 -4.40 0.75 -0.14 -4.69 -6.10 -5.98 -1.89 4.59 0.62 -1.32 -7.44 -2.17
Cell Periphery 3.66 3.66 3.34 -4.87 -4.96 2.83 -3.14 -4.22 -6.23 0.12 3.67 1.33 0.13 -7.37 -1.90
Cytoplasm 2.27 2.51 2.46 0.79 -0.74 -0.69 -4.19 -6.37 -4.66 -1.35 0.35 1.02 0.20 -0.26 -1.66
Cytoplasmic Foci 5.10 -0.50 5.77 2.43 6.27 -2.16 -0.37 -5.07 -3.07 -4.82 -1.24 -1.91 -1.64 -0.37 0.55
Eisosomes 3.15 2.60 2.67 -1.54 -0.09 -0.67 -5.87 -2.48 -2.23 -0.93 -1.86 -2.87 -4.16 -3.26 -2.70
Endoplasmic Reticulum 4.03 3.83 3.89 -4.94 1.08 -0.01 -2.05 -2.99 -2.96 1.04 3.57 -0.80 0.99 -4.64 1.21
Endosome 8.13 3.49 9.00 1.91 5.85 -1.33 1.78 -5.39 -3.94 -7.33 0.25 1.97 -1.10 -1.43 -3.56
Golgi 8.76 7.90 7.50 -6.89 -1.90 -3.31 -6.18 -13.12 -11.17 -8.83 2.09 -1.01 -9.78 -13.14 -9.02
Lipid Particles -1.70 -3.06 0.83 5.02 4.10 1.18 2.54 2.19 2.09 -1.15 -0.46 1.09 2.40 5.42 3.05
Mitochondria -20.79 -8.74 -19.04 5.74 -10.40 2.04 8.66 15.06 13.21 7.69 -3.63 4.99 8.22 13.87 2.82
Mitotic Spindle 3.43 -2.49 1.69 -5.97 4.57 0.76 -3.51 -5.43 -6.36 -2.81 1.92 -4.83 -5.83 -8.83 -0.64
None -1.86 -5.57 -5.29 -5.68 3.00 0.19 -10.15 -6.49 -5.29 4.34 -0.94 -11.40 -9.53 -7.89 4.30
Nuclear Periphery 1.98 -4.14 1.35 -3.87 4.48 0.95 -0.71 -1.04 -4.29 -0.52 1.42 -3.84 -0.49 -5.66 4.06
Nuclear Periphery Foci 1.37 -4.24 2.45 0.96 4.75 1.18 -0.41 -0.18 -3.69 0.37 0.66 -2.90 0.43 -0.54 3.92
Nucleolus -1.23 -2.23 -1.07 0.36 2.22 0.05 -0.40 1.13 1.09 1.71 0.41 -1.32 1.18 1.13 2.74
Nucleus 1.31 -0.61 1.41 1.34 1.79 -0.42 -0.50 0.74 0.84 1.06 0.36 -1.05 1.75 1.22 2.19
Peroxisomes -0.33 -1.01 1.50 3.56 3.08 3.49 2.63 1.07 -2.22 -1.42 0.78 1.90 1.95 1.39 0.01
Vacuole 5.59 0.71 5.13 -4.41 7.47 -2.40 -7.42 -6.89 -5.13 -1.32 2.63 -5.63 -2.59 -6.54 3.75
Vacuole Periphery 5.77 0.16 4.40 -7.86 6.35 -2.77 -10.35 -10.43 -8.57 0.12 2.52 -9.25 -7.73 -11.45 3.15
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial outer membrane protein; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins; TOM71 has a paralog, TOM70, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (93%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Tom71

Tom71


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tom71-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available