Standard name
Human Ortholog
Description Protein of unknown function; may be involved in chitin biosynthesis by regulation of Chs3p export from the ER; relocalizes from bud neck to ER upon DNA replication stress
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.21 0.09 0.07 0.06 0 0 0 0 0 0 0 0 0.06 0.06 0 0.06 0 0 0.11 0.05 0 0.06 0.08 0.09
Bud 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.08 0.09
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0.05 0.1 0.08 0.08
Bud Site 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0
Cytoplasm 0.53 0.53 0.46 0.71 0.47 0.57 0.65 0.69 0.68 0.69 0.75 0.78 0.59 0.7 0.83 0.48 0.53 0.51 0.09 0 0 0 0 0
Endoplasmic Reticulum 0.08 0.1 0.13 0.09 0 0 0 0 0 0 0 0 0.28 0.19 0.08 0 0 0.05 0.16 0.12 0.17 0.2 0.23 0.22
Endosome 0.06 0.07 0.09 0 0.13 0 0 0 0 0 0 0 0 0 0 0.1 0.08 0.05 0.13 0.05 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.05 0.06 0.1 0.09 0.11 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0.09 0.06 0 0 0 0 0 0 0 0 0.06 0 0.05 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0.21 0.27 0.19 0.46 0.36 0.31 0.26 0.37 0.3 0.21 0.2 0 0 0 0.45 0.43 0.38 0.22 0.55 0.61 0.41 0.4 0.37
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 16 40 23 12 4 3 3 3 2 1 4 3 14 15 11 7 4 6 14 29 16 16 28 34
Bud 4 13 8 2 4 4 3 5 6 9 7 12 6 8 1 1 1 0 4 24 18 36 28 34
Bud Neck 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 6 44 19 29 30 32
Bud Site 4 13 11 3 3 3 1 2 1 3 4 3 2 2 1 1 0 0 – – – – – –
Cell Periphery 1 3 3 3 1 1 2 4 1 4 1 0 9 11 19 1 2 2 1 1 0 3 7 12
Cytoplasm 41 230 162 143 177 215 258 298 189 274 217 336 132 182 254 60 95 76 11 18 7 5 9 11
Endoplasmic Reticulum 6 45 47 19 12 16 12 11 1 4 2 1 63 50 25 1 4 7 21 66 72 59 82 88
Endosome 5 31 31 5 48 6 2 10 1 10 1 8 4 1 8 12 14 7 16 28 19 4 5 7
Golgi 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 3 2 3 5 11 4 3 9 4
Mitochondria 3 9 4 0 5 17 21 26 27 35 32 44 0 1 0 0 2 3 4 13 5 10 9 12
Nucleus 1 6 4 8 15 34 25 17 12 3 3 6 2 0 1 7 6 8 1 1 0 0 0 0
Nuclear Periphery 0 1 0 0 0 0 4 1 1 2 1 0 0 0 0 0 0 0 1 1 1 1 2 5
Nucleolus 4 1 2 1 3 4 5 2 0 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 3 3 0 2 0 2 1 2 1 1 1 0 0 0 0 1 2 2 1 0 0 0 0
SpindlePole 5 9 12 2 8 1 1 2 2 4 1 5 6 4 0 0 1 4 2 1 0 0 0 0
Vac/Vac Membrane 4 91 95 38 170 135 123 113 102 119 61 84 5 2 4 56 78 56 29 312 265 120 146 143
Unique Cell Count 78 432 350 201 373 375 397 429 279 398 288 430 222 259 305 125 180 148 133 563 434 294 366 393
Labelled Cell Count 95 495 405 236 452 439 463 495 347 469 337 507 243 278 325 149 210 174 133 563 434 294 366 393


Ambiguous, Bud, Bud Neck, Cytoplasm, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.2 8.4 7.1 7.6 7.2 6.7 5.8 5.8 5.4 5.5 5.2 5.4 8.3 7.2 6.8 10.1 9.9 10.0 11.6 12.3 12.9
Std Deviation (1e-4) 2.2 1.9 1.1 1.3 1.4 1.2 1.4 1.1 1.1 1.2 1.3 1.1 1.1 1.4 1.1 2.0 1.7 1.8 2.3 2.4 2.9
Intensity Change (Log2) – – – 0.11 0.02 -0.07 -0.3 -0.28 -0.39 -0.38 -0.44 -0.39 0.22 0.03 -0.05 0.51 0.49 0.5 0.71 0.8 0.87

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.3 -3.9 -4.2 -4.3 -4.5 -3.7 -4.9 -3.2 -4.5 -0.1 -0.4 -1.7 -0.4 -2.2 -1.1
Bud 0 -1.3 -1.3 -1.7 -1.2 -0.1 0 0.1 0.4 0.3 0.6 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site -1.2 -2.3 -2.3 -3.1 -2.9 -2.5 -2.4 -1.5 -2.6 -1.8 -2.0 -2.7 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 2.8 3.8 0 0 0
Cytoplasm 5.7 0.3 3.0 5.1 6.5 5.4 6.2 7.4 9.2 3.1 5.9 9.8 0.3 1.4 1.0
Endoplasmic Reticulum -1.4 -5.0 -4.4 -5.3 -5.7 -6.1 -6.7 -6.0 -7.6 4.4 2.0 -2.1 -4.0 -4.1 -2.9
Endosome -2.9 1.7 -4.4 -5.5 -4.1 -4.8 -3.8 -4.9 -4.5 -3.4 -4.6 -3.4 0.2 -0.4 -1.6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.7 3.1 3.5 4.9 4.7 5.4 5.3 0 0 0 0 0 0
Nucleus 0 2.4 4.8 3.6 2.4 2.5 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole -1.7 -1.1 -3.2 -3.3 -3.1 -2.3 -2.3 -2.7 -2.2 -0.5 -1.4 -3.3 0 0 0
Vacuole -2.2 5.1 2.6 1.2 -0.3 2.5 0.8 -1.7 -2.5 -7.6 -8.8 -9.2 3.6 3.8 2.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6656 4.9778 4.529 4.2696 4.0092 4.5765 6.243 7.7727 7.5044 7.0892 6.9738 7.8374 5.165 6.8673 6.2382 6.3534 5.1857 6.475
Actin 0.0096 0.0042 0.0101 0.0005 0.0004 0.0015 0.0335 0.0023 0.012 0.0337 0.0037 0.0026 0.0217 0.0014 0.0034 0.0003 0.0233 0.002
Bud 0.007 0.0052 0.0058 0.0012 0.0008 0.0016 0.0028 0.0022 0.0025 0.0018 0.0014 0.0013 0.0027 0.0031 0.0018 0.0006 0.0007 0.0011
Bud Neck 0.018 0.0185 0.0886 0.012 0.0146 0.346 0.0301 0.0131 0.0852 0.0029 0.0033 0.3213 0.0202 0.0269 0.106 0.0019 0.0014 0.3547
Bud Periphery 0.0113 0.0066 0.0063 0.0019 0.0016 0.0041 0.0062 0.0044 0.0054 0.0038 0.0048 0.0036 0.0037 0.0043 0.0034 0.0016 0.001 0.0037
Bud Site 0.1069 0.1724 0.0844 0.0136 0.0075 0.0089 0.1168 0.1272 0.1137 0.009 0.0034 0.0024 0.0856 0.1465 0.0682 0.0017 0.0022 0.0037
Cell Periphery 0.0261 0.0163 0.0057 0.002 0.003 0.0067 0.0297 0.0166 0.018 0.0082 0.0139 0.0098 0.0255 0.0261 0.0126 0.0063 0.0007 0.0106
Cytoplasm 0.1885 0.2356 0.1547 0.0845 0.1317 0.1463 0.1326 0.1894 0.102 0.0535 0.128 0.1253 0.2107 0.1888 0.1003 0.0709 0.1874 0.1211
Cytoplasmic Foci 0.0618 0.0331 0.0548 0.0455 0.0819 0.0289 0.0416 0.027 0.0404 0.0213 0.0342 0.0183 0.029 0.0276 0.0485 0.0272 0.0668 0.0277
Eisosomes 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0003 0 0.0001 0.0001 0.0002 0 0.0002 0 0.0001 0 0.0002 0
Endoplasmic Reticulum 0.0831 0.0635 0.051 0.0258 0.0396 0.0598 0.1289 0.0932 0.073 0.0539 0.0359 0.1041 0.1439 0.0884 0.0707 0.0874 0.0589 0.103
Endosome 0.1788 0.1397 0.2708 0.3794 0.3975 0.1019 0.1427 0.1058 0.2085 0.2482 0.3258 0.1031 0.133 0.1245 0.2792 0.3713 0.4243 0.0878
Golgi 0.0163 0.0126 0.0305 0.0134 0.0211 0.0078 0.0205 0.0096 0.0404 0.0163 0.0122 0.0079 0.0142 0.0146 0.0454 0.0238 0.0797 0.0132
Lipid Particles 0.0693 0.0213 0.0124 0.0086 0.0329 0.0109 0.0649 0.0442 0.0247 0.0084 0.0189 0.0128 0.0646 0.0472 0.0327 0.0166 0.0161 0.0188
Mitochondria 0.0033 0.0044 0.0075 0.0044 0.0036 0.0044 0.0024 0.001 0.0041 0.0648 0.0024 0.0019 0.0029 0.0015 0.0066 0.0025 0.0188 0.002
None 0.016 0.0031 0.0073 0.0097 0.0011 0.0045 0.0096 0.0017 0.0066 0.0004 0.0059 0.002 0.0073 0.0019 0.0071 0.0016 0.0125 0.0024
Nuclear Periphery 0.0123 0.0067 0.0065 0.0064 0.0063 0.0074 0.0168 0.0084 0.0064 0.0058 0.0129 0.0068 0.0115 0.007 0.006 0.0115 0.0155 0.0055
Nucleolus 0.0058 0.0028 0.0017 0.0022 0.0012 0.0039 0.002 0.0017 0.0019 0.0011 0.0021 0.0007 0.0016 0.0026 0.0016 0.0003 0.0004 0.0009
Nucleus 0.0142 0.0079 0.0046 0.0046 0.004 0.0061 0.0066 0.006 0.004 0.0046 0.0065 0.0035 0.0047 0.0056 0.0037 0.0028 0.004 0.0034
Peroxisomes 0.0106 0.0008 0.0045 0.0025 0.0057 0.002 0.0094 0.0006 0.0025 0.0126 0.0016 0.0003 0.0013 0.0005 0.001 0.0005 0.005 0.0007
Punctate Nuclear 0.0068 0.0013 0.001 0.004 0.0018 0.0089 0.0081 0.0009 0.0008 0.0004 0.0163 0.0012 0.002 0.0009 0.0008 0.0005 0.002 0.0008
Vacuole 0.1479 0.237 0.1833 0.3505 0.2304 0.2287 0.1902 0.3373 0.2371 0.433 0.3525 0.2607 0.2074 0.2745 0.1917 0.3472 0.0696 0.228
Vacuole Periphery 0.0061 0.0069 0.0085 0.0272 0.0135 0.0096 0.0043 0.0073 0.0105 0.016 0.0143 0.01 0.0065 0.0062 0.009 0.0234 0.0094 0.0089

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 38.8686 30.0788 23.0894 37.0569 35.3516 18.5538 25.6934 33.267 30.1119 39.9719
Translational Efficiency 1.2553 1.1909 1.4742 0.9862 1.087 3.308 1.3781 0.9587 1.1277 0.9939

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1697 1375 309 1376 1981 1722 1253 1695 3678 3097 1562 3071

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 865.06 1018.20 1126.57 1100.83 911.04 946.31 1088.50 1162.76 889.83 978.23 1096.03 1135.01
Standard Deviation 118.19 172.95 148.22 193.80 143.82 154.54 148.16 171.14 134.58 166.84 148.94 184.23
Intensity Change Log 2 — 0.235149 0.381065 0.347720 — 0.054798 0.256755 0.351967 — 0.145457 0.318639 0.349900

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000984 0.001112 0.050397 0.009309 0.001399 0.000706 0.046484 0.009859 0.001207 0.000886 0.047258 0.009612
Bud Neck 0.085464 0.025663 0.075741 0.036969 0.056681 0.024411 0.039820 0.042082 0.069961 0.024967 0.046926 0.039791
Bud Site 0.107647 0.073681 0.278846 0.243012 0.096116 0.063735 0.267799 0.201090 0.101436 0.068151 0.269984 0.219874
Cell Periphery 0.007225 0.012466 0.005702 0.003839 0.007193 0.019947 0.002889 0.006354 0.007208 0.016626 0.003445 0.005227
Cytoplasm 0.085742 0.040127 0.047606 0.117483 0.082614 0.029018 0.051763 0.106515 0.084057 0.033950 0.050941 0.111429
Cytoplasmic Foci 0.041318 0.027633 0.067013 0.065705 0.056281 0.014426 0.113222 0.059548 0.049377 0.020290 0.104081 0.062307
Eisosomes 0.000428 0.000100 0.000722 0.000291 0.000239 0.000079 0.000423 0.000273 0.000326 0.000088 0.000482 0.000281
Endoplasmic Reticulum 0.092343 0.060335 0.163881 0.011562 0.084204 0.064552 0.057733 0.040370 0.087960 0.062680 0.078732 0.027462
Endosome 0.078522 0.058410 0.072584 0.109347 0.081061 0.046747 0.169170 0.118765 0.079889 0.051925 0.150063 0.114545
Golgi 0.009178 0.006386 0.027549 0.016508 0.013454 0.004618 0.103524 0.023252 0.011481 0.005403 0.088494 0.020230
Lipid Particles 0.012696 0.003896 0.054833 0.014381 0.010762 0.002971 0.045354 0.023942 0.011654 0.003382 0.047229 0.019658
Mitochondria 0.005426 0.001798 0.000231 0.001986 0.005480 0.002372 0.006348 0.003046 0.005455 0.002117 0.005138 0.002571
Mitotic Spindle 0.000301 0.000142 0.005753 0.012953 0.000399 0.000095 0.005385 0.008488 0.000353 0.000116 0.005458 0.010489
None 0.000291 0.000052 0.000039 0.000596 0.000245 0.000041 0.000207 0.000173 0.000266 0.000046 0.000174 0.000362
Nuclear Periphery 0.000189 0.000128 0.000462 0.000398 0.000182 0.000107 0.000101 0.000271 0.000185 0.000116 0.000172 0.000328
Nuclear Periphery Foci 0.000670 0.000702 0.020063 0.004510 0.000748 0.000416 0.003074 0.002606 0.000712 0.000543 0.006435 0.003459
Nucleolus 0.000400 0.000332 0.000075 0.000275 0.000432 0.000403 0.000066 0.000259 0.000417 0.000371 0.000068 0.000266
Nucleus 0.003316 0.001334 0.004903 0.003093 0.003326 0.001078 0.001097 0.002386 0.003322 0.001191 0.001850 0.002703
Peroxisomes 0.002391 0.001183 0.010600 0.006351 0.002923 0.000992 0.009405 0.004249 0.002678 0.001077 0.009641 0.005191
Vacuole 0.447636 0.652987 0.112033 0.331887 0.475061 0.703349 0.070071 0.334139 0.462407 0.680990 0.078372 0.333130
Vacuole Periphery 0.017833 0.031533 0.000965 0.009546 0.021201 0.019935 0.006066 0.012334 0.019647 0.025084 0.005057 0.011085

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.33 -6.94 -5.85 -5.63 5.70 2.99 -14.34 -8.21 -8.99 11.08 1.45 -15.96 -9.89 -10.20 12.58
Bud Neck 12.65 1.34 10.44 -3.16 4.70 9.32 4.31 4.06 -6.00 -0.56 15.64 6.47 10.37 -6.60 2.44
Bud Site 4.88 -8.39 -12.68 -16.42 1.96 5.30 -16.93 -12.20 -16.58 5.98 7.24 -18.90 -17.53 -23.32 5.58
Cell Periphery -3.56 1.33 4.22 6.44 1.77 -8.87 6.49 0.98 8.99 -4.00 -9.10 6.82 3.25 11.05 -2.82
Cytoplasm 10.34 4.97 -6.71 -15.17 -9.48 13.50 6.24 -5.04 -17.32 -10.71 17.00 8.36 -8.23 -22.99 -15.02
Cytoplasmic Foci 4.77 -3.97 -6.58 -10.49 0.37 14.45 -12.27 -0.81 -16.31 11.87 14.24 -14.67 -4.83 -18.87 11.07
Eisosomes 3.92 -2.40 1.54 -2.92 4.10 8.27 -5.69 -1.00 -6.96 3.98 5.96 -3.27 1.07 -5.95 5.10
Endoplasmic Reticulum 5.64 -4.32 17.69 12.67 9.71 4.07 4.47 9.23 5.90 3.39 6.86 1.68 18.09 12.29 10.04
Endosome 5.13 1.02 -4.94 -9.06 -4.17 9.30 -15.16 -7.40 -15.04 7.89 10.41 -14.45 -8.85 -17.30 7.20
Golgi 2.47 -3.94 -3.57 -5.26 2.48 6.60 -19.83 -4.63 -10.43 17.27 6.82 -20.36 -5.89 -11.45 17.83
Lipid Particles 8.39 -6.70 -1.14 -7.15 6.31 8.91 -11.82 -6.76 -11.41 6.36 12.26 -13.46 -6.17 -13.43 9.67
Mitochondria 5.04 7.74 4.69 -0.17 -4.59 4.40 -0.80 3.38 -0.89 3.44 6.57 0.49 5.58 -0.86 3.56
Mitotic Spindle 0.83 -4.30 -6.92 -7.03 -3.37 1.41 -5.87 -6.34 -6.62 -2.24 1.63 -7.10 -9.37 -9.64 -4.16
None 2.13 2.19 -0.71 -1.37 -1.39 3.35 0.25 0.89 -2.11 0.21 3.59 0.68 -0.46 -1.75 -0.84
Nuclear Periphery 1.53 -3.51 -3.34 -3.83 0.73 1.50 1.79 -1.74 -3.36 -3.99 2.11 -0.34 -3.66 -5.08 -3.47
Nuclear Periphery Foci -0.20 -5.99 -4.72 -4.65 4.69 2.06 -6.11 -6.47 -7.69 1.09 1.47 -7.87 -6.93 -7.30 3.69
Nucleolus 1.74 9.28 1.46 0.51 -3.05 -0.17 17.40 5.84 1.11 -8.93 0.13 19.78 3.91 1.22 -6.35
Nucleus 8.22 -2.24 -0.97 -5.99 1.78 9.54 8.32 2.76 -6.72 -5.65 12.66 4.52 1.06 -8.73 -3.26
Peroxisomes 4.56 -4.74 -6.61 -9.43 2.43 6.62 -8.21 -3.11 -9.07 6.38 8.01 -9.79 -7.05 -13.02 6.04
Vacuole -17.56 25.54 8.71 25.65 -17.14 -21.91 47.64 12.65 34.70 -30.66 -28.06 57.71 15.21 42.87 -38.16
Vacuole Periphery -7.96 20.22 7.72 13.10 -9.29 0.95 15.81 7.44 5.81 -6.12 -5.08 21.09 10.56 13.38 -7.89
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein of unknown function; may be involved in chitin biosynthesis by regulation of Chs3p export from the ER; relocalizes from bud neck to ER upon DNA replication stress
Localization
Cell Percentages vacuole (57%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Chs7

Chs7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Chs7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available