Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.07 0.09 0.17 0.14 0.11 0.14 0.12 0.12 0.12 0.11 0.1 0.12 0.05 0.06 0 0 0.05 0.06 0.06 0.07 0.12 0.09 0.06 0.09
Bud 0.07 0.06 0.06 0.06 0.06 0.14 0.1 0.14 0.14 0.13 0.13 0.12 0.07 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.13 0.06 0.06 0.06 0.09
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.21 0.18 0.33 0.27 0.19 0.25 0.22 0.19 0.23 0.19 0.21 0.19 0.33 0.42 0.4 0.26 0.38 0.3 0.17 0.25 0.49 0.46 0.34 0.35
Cytoplasm 0.78 0.83 0.72 0.83 0.82 0.81 0.82 0.78 0.8 0.8 0.84 0.81 0.81 0.77 0.7 0.66 0.49 0.5 0.26 0.26 0.1 0.18 0.23 0.17
Endoplasmic Reticulum 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.15 0.07 0.11 0.07 0.09 0.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.05 0.07 0.07 0.1 0 0.05 0 0 0 0 0 0 0 0 0 0 0.06 0.08 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.17 0.15 0.2 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0.08 0.11 0.16 0.2 0.14 0.05 0.05 0.07 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 13 18 38 22 28 54 46 61 42 45 36 57 6 11 9 4 10 9 12 16 28 17 18 31
Bud 13 11 14 9 16 54 38 72 49 53 51 58 8 2 6 3 1 2 5 4 1 2 5 9
Bud Neck 0 0 2 1 5 1 0 0 0 0 0 0 0 1 1 0 0 0 22 29 13 11 16 30
Bud Site 0 1 0 0 1 0 1 1 1 2 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 42 35 73 42 50 99 86 95 82 81 79 91 38 73 99 45 71 43 39 55 116 91 99 121
Cytoplasm 154 164 158 129 216 320 313 393 284 337 318 380 92 135 171 114 92 72 59 57 22 35 67 57
Endoplasmic Reticulum 9 3 2 1 5 10 4 11 6 12 9 5 1 4 11 2 3 0 34 15 26 13 26 34
Endosome 0 0 0 0 0 4 0 3 0 1 0 6 1 0 1 0 1 0 1 3 1 0 5 3
Golgi 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 3 2 1 2 1 0 0 0
Mitochondria 2 3 8 0 2 18 28 35 36 18 20 13 2 0 0 1 5 2 3 4 6 12 22 18
Nucleus 1 1 0 1 2 3 0 5 1 4 3 2 2 1 0 29 28 29 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 0 0 2 2 0 1 0 2 1 1 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 1 2 1 3 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 3 1 1 2 1 1 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 2 0 2 7 1 15 4 1 5 1 3 0 0 3 0 0 1 0 0 1 0 0 0
Vac/Vac Membrane 1 1 1 0 5 2 6 5 2 18 9 22 0 0 0 13 20 23 45 30 12 9 20 26
Unique Cell Count 198 198 219 156 263 397 383 503 353 419 378 470 114 175 246 173 186 145 228 222 236 199 291 342
Labelled Cell Count 237 239 300 208 338 568 541 690 506 580 527 642 151 228 302 212 234 183 228 222 236 199 291 342


Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 5.7 5.7 6.1 6.3 5.7 6.3 6.6 6.1 6.4 6.6 6.4 6.2 6.4 6.6 11.2 11.3 11.0 5.7 5.7 6.3
Std Deviation (1e-4) 1.7 1.4 1.7 2.2 2.4 1.7 3.2 1.6 1.5 1.4 1.6 1.3 1.4 1.3 1.2 2.7 3.2 2.6 1.3 1.3 1.7
Intensity Change (Log2) – – – 0.09 0.14 -0.01 0.13 0.2 0.1 0.17 0.21 0.16 0.1 0.17 0.2 0.96 0.98 0.94 -0.02 -0.01 0.13

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.8 -2.1 -1.2 -1.8 -1.9 -1.8 -2.4 -2.8 -1.9 -3.1 -3.3 -4.9 -4.8 -3.7 -3.1
Bud -0.2 -0.1 2.7 1.5 3.0 2.8 2.4 2.7 2.4 0.2 -2.6 -2.1 -2.2 -3.1 -2.3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.3 -3.6 -2.2 -2.9 -4.2 -2.6 -3.9 -3.4 -4.0 0 1.7 1.5 -1.6 1.0 -0.7
Cytoplasm 2.4 2.6 2.4 2.7 1.7 2.3 2.4 3.5 2.6 1.7 1.1 -0.6 -1.3 -4.7 -4.4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 2.3 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0.5 1.8 1.7 2.9 0.4 0.9 -0.6 0 0 0 0 -0.5 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 6.3 6.0 6.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 3.0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 2.7 0 2.9 0 0 0 3.7 4.7 5.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.1283 0.6311 0.628 -0.0791 -0.3614 0.5181 1.3273 3.0695 2.5059 1.8781 2.0115 2.2926 0.3253 0.9019 1.2383 1.0665 0.4417 1.1291
Actin 0.0246 0.0147 0.0135 0.0109 0.008 0.0107 0.0116 0.0022 0.0125 0.0066 0.0207 0.0052 0.0201 0.0031 0.0124 0.0019 0.0177 0.0033
Bud 0.0006 0.0009 0.001 0.0022 0.0019 0.0018 0.0028 0.0006 0.0017 0.0009 0.0018 0.0012 0.0002 0.0004 0.001 0.0006 0.0003 0.0006
Bud Neck 0.0095 0.0056 0.0166 0.0309 0.006 0.0376 0.0032 0.0084 0.0183 0.0353 0.0157 0.0495 0.014 0.0041 0.012 0.01 0.0022 0.0221
Bud Periphery 0.0043 0.0032 0.0071 0.0203 0.0128 0.0138 0.0124 0.0026 0.0131 0.0045 0.0139 0.0079 0.002 0.0017 0.0047 0.0058 0.0012 0.0062
Bud Site 0.0166 0.0983 0.0666 0.0113 0.0052 0.0038 0.0152 0.1026 0.0417 0.0176 0.0035 0.002 0.0153 0.1009 0.0397 0.0019 0.0007 0.0031
Cell Periphery 0.16 0.1426 0.1798 0.2075 0.0797 0.1181 0.1475 0.1047 0.1874 0.1458 0.1774 0.1301 0.1752 0.1091 0.2244 0.2786 0.1145 0.2488
Cytoplasm 0.4141 0.512 0.4228 0.3371 0.5923 0.5591 0.5146 0.5903 0.5713 0.5536 0.4901 0.6223 0.3262 0.3144 0.4118 0.5259 0.4419 0.5636
Cytoplasmic Foci 0.0137 0.0064 0.004 0.012 0.0037 0.0049 0.0097 0.0029 0.0041 0.0045 0.0029 0.0095 0.027 0.0068 0.0062 0.0035 0.0113 0.0119
Eisosomes 0.0045 0.0038 0.0029 0.004 0.001 0.0014 0.0015 0.0005 0.0013 0.0004 0.0009 0.0003 0.0043 0.0019 0.0022 0.0009 0.0002 0.0003
Endoplasmic Reticulum 0.0071 0.0034 0.0042 0.0038 0.0052 0.0038 0.0071 0.004 0.0051 0.0066 0.0077 0.0032 0.0048 0.0026 0.006 0.0025 0.0016 0.0031
Endosome 0.0072 0.0013 0.0006 0.0048 0.0009 0.0011 0.0033 0.0008 0.002 0.0011 0.0014 0.0047 0.0094 0.0004 0.0065 0.0005 0.0229 0.0068
Golgi 0.0023 0.0011 0.0007 0.001 0.0006 0.0007 0.0016 0.0003 0.0014 0.0008 0.0024 0.0021 0.0025 0.0004 0.005 0.0003 0.0838 0.0013
Lipid Particles 0.0084 0.001 0.0012 0.0029 0.0013 0.0016 0.0066 0.0027 0.002 0.0058 0.0041 0.0026 0.0132 0.002 0.0023 0.0014 0.0021 0.0088
Mitochondria 0.0012 0.0003 0.0003 0.001 0.0002 0.0005 0.001 0.0001 0.0007 0.0002 0.0048 0.0006 0.0004 0.0002 0.0136 0.0005 0.0029 0.0007
None 0.3068 0.2015 0.2731 0.3232 0.2758 0.2339 0.2469 0.1607 0.1265 0.1935 0.2441 0.1451 0.3549 0.4448 0.2422 0.1581 0.2906 0.094
Nuclear Periphery 0.0013 0.0003 0.0003 0.0005 0.0003 0.0006 0.0013 0.0003 0.0005 0.0004 0.0004 0.0004 0.0018 0.0003 0.0005 0.0001 0.0001 0.0084
Nucleolus 0.0017 0.0003 0.0005 0.0007 0.0002 0.0003 0.0005 0.0002 0.0003 0.0003 0.0002 0.0003 0.0002 0.0005 0.0003 0.0004 0 0.0004
Nucleus 0.0011 0.0007 0.0007 0.0009 0.0007 0.0009 0.001 0.0007 0.0013 0.0008 0.0004 0.001 0.0037 0.0005 0.0006 0.0004 0.0001 0.001
Peroxisomes 0.0022 0.0001 0.0002 0.0013 0.0001 0.0002 0.0016 0 0.0007 0.0001 0.0008 0.0004 0.014 0.0004 0.0004 0.0002 0.0014 0.002
Punctate Nuclear 0.0033 0.0005 0.0005 0.0019 0.0002 0.0005 0.0021 0.0002 0.0003 0.0005 0.0002 0.001 0.0056 0.0005 0.0003 0.0001 0.0001 0.0063
Vacuole 0.0094 0.0021 0.0034 0.0214 0.0037 0.0047 0.0083 0.0151 0.0077 0.0207 0.0067 0.0105 0.0051 0.0051 0.0073 0.0061 0.004 0.007
Vacuole Periphery 0.0003 0.0001 0.0001 0.0003 0.0001 0.0001 0.0002 0 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0006 0.0001 0.0003 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.648 15.2927 26.1 26.8192 21.071 25.6464 24.3533 34.9608 32.4129 33.2875
Translational Efficiency 1.1255 1.96 1.197 1.247 1.6113 1.7472 1.9666 1.1436 1.6303 1.4332

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
447 1883 656 94 1877 1817 2675 2297 2324 3700 3331 2391

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 777.15 846.34 906.49 1283.22 768.53 755.00 933.09 1080.17 770.19 801.48 927.85 1088.15
Standard Deviation 105.83 135.28 122.18 224.84 113.07 122.45 137.91 203.86 111.77 136.97 135.37 208.49
Intensity Change Log 2 — 0.123044 0.222098 0.723504 — -0.025625 0.279915 0.491085 — 0.051038 0.251135 0.612616

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003963 0.016431 0.016175 0.026691 0.007087 0.018436 0.033844 0.028512 0.006486 0.017416 0.030364 0.028441
Bud Neck 0.096216 0.091569 0.053573 0.019319 0.087534 0.111943 0.076481 0.041892 0.089204 0.101574 0.071970 0.041004
Bud Site 0.034743 0.087898 0.089884 0.074418 0.047334 0.096579 0.099210 0.150815 0.044912 0.092161 0.097373 0.147811
Cell Periphery 0.093812 0.063803 0.116127 0.486898 0.107456 0.048090 0.188846 0.286022 0.104831 0.056086 0.174525 0.293919
Cytoplasm 0.500069 0.487796 0.293291 0.155282 0.524467 0.445355 0.359645 0.376113 0.519774 0.466954 0.346577 0.367431
Cytoplasmic Foci 0.049406 0.073299 0.044694 0.010986 0.045500 0.089036 0.006082 0.006198 0.046251 0.081027 0.013686 0.006386
Eisosomes 0.027449 0.022481 0.024636 0.008359 0.045102 0.022950 0.049154 0.007734 0.041706 0.022711 0.044326 0.007759
Endoplasmic Reticulum 0.004052 0.005857 0.042428 0.013864 0.004437 0.004283 0.011530 0.004603 0.004363 0.005084 0.017615 0.004967
Endosome 0.010008 0.009615 0.003661 0.001518 0.010375 0.016079 0.000764 0.002132 0.010304 0.012789 0.001334 0.002107
Golgi 0.004959 0.009186 0.001728 0.001167 0.006979 0.011147 0.000784 0.001386 0.006591 0.010149 0.000970 0.001378
Lipid Particles 0.007168 0.007827 0.006921 0.005677 0.010498 0.010206 0.003505 0.004041 0.009858 0.008995 0.004178 0.004105
Mitochondria 0.001142 0.003580 0.000328 0.000072 0.003254 0.009276 0.000876 0.001460 0.002847 0.006377 0.000768 0.001405
Mitotic Spindle 0.000150 0.000118 0.000143 0.000221 0.000096 0.001760 0.000128 0.001806 0.000106 0.000924 0.000131 0.001744
None 0.000835 0.001137 0.001813 0.000046 0.001153 0.001266 0.000461 0.000253 0.001091 0.001200 0.000727 0.000245
Nuclear Periphery 0.000131 0.000081 0.000426 0.000254 0.000156 0.000078 0.000151 0.000131 0.000151 0.000079 0.000205 0.000136
Nuclear Periphery Foci 0.000591 0.000495 0.002535 0.002917 0.000446 0.000285 0.000695 0.000365 0.000474 0.000392 0.001057 0.000465
Nucleolus 0.000200 0.000214 0.000219 0.000023 0.000241 0.000273 0.000061 0.000057 0.000233 0.000243 0.000092 0.000055
Nucleus 0.038593 0.042018 0.192418 0.013157 0.038083 0.037578 0.093718 0.013211 0.038181 0.039838 0.113156 0.013209
Peroxisomes 0.003770 0.007528 0.001156 0.000727 0.005013 0.013681 0.001184 0.002254 0.004774 0.010549 0.001178 0.002194
Vacuole 0.122014 0.068291 0.107732 0.178251 0.054138 0.060264 0.072798 0.070017 0.067193 0.064349 0.079678 0.074273
Vacuole Periphery 0.000728 0.000778 0.000112 0.000151 0.000653 0.001437 0.000084 0.001000 0.000667 0.001102 0.000090 0.000967

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -10.83 -7.60 -2.46 -1.08 -1.15 -9.01 -18.47 -13.54 -5.14 2.59 -12.66 -19.68 -14.19 -6.42 0.97
Bud Neck 0.64 5.74 10.79 16.67 6.56 -5.15 3.20 13.00 17.58 11.35 -3.29 5.40 14.86 20.24 11.09
Bud Site -10.58 -7.09 -2.76 1.06 0.94 -11.15 -13.15 -19.93 -9.04 -9.40 -14.59 -14.88 -20.91 -10.75 -9.73
Cell Periphery 3.34 -1.48 -10.32 -11.40 -9.92 11.53 -12.69 -21.47 -30.90 -11.58 11.14 -12.12 -23.59 -32.30 -14.96
Cytoplasm 1.05 15.30 15.47 16.28 6.07 10.16 24.09 18.94 8.31 -2.43 8.58 28.30 20.61 14.16 -3.31
Cytoplasmic Foci -4.67 0.72 6.90 13.94 7.17 -10.33 16.15 15.86 23.33 -0.19 -11.34 14.42 18.14 31.89 7.22
Eisosomes 1.57 1.17 5.77 7.23 6.57 10.25 -1.32 20.83 10.91 24.56 10.86 -0.80 21.42 14.83 25.36
Endoplasmic Reticulum -1.27 -9.70 -2.78 -2.34 5.76 0.22 -8.22 -0.22 -0.42 8.05 -1.10 -12.46 -0.89 0.21 11.80
Endosome 0.24 4.24 5.66 10.94 4.04 -4.18 11.26 9.28 12.80 -5.04 -2.58 12.00 10.49 16.21 -2.78
Golgi -3.67 3.41 3.92 12.18 2.14 -5.16 17.08 12.31 12.70 -2.08 -6.00 16.22 11.99 16.03 -1.49
Lipid Particles -0.66 0.10 1.28 2.22 1.49 0.21 6.86 6.13 6.67 -0.95 0.91 6.69 6.43 7.83 0.29
Mitochondria -5.26 2.19 2.66 11.88 2.25 -6.97 4.60 3.20 10.73 -2.38 -6.26 4.90 3.04 11.49 -2.73
Mitotic Spindle 0.43 -0.09 -0.82 -2.59 -1.41 -3.09 -1.45 -2.56 -0.09 -2.52 -3.08 -1.14 -2.55 -1.20 -2.52
None -0.52 -1.38 1.60 4.48 3.27 -0.26 2.03 2.63 3.34 2.30 -0.32 1.14 2.89 4.81 3.65
Nuclear Periphery 4.13 -11.40 -3.23 -4.48 3.87 3.13 -0.01 0.91 -4.96 2.06 3.58 -3.15 0.62 -5.95 6.60
Nuclear Periphery Foci 1.78 -10.25 -5.26 -5.49 -0.55 3.04 -4.68 1.68 -1.86 6.98 2.07 -10.01 0.14 -1.93 10.13
Nucleolus -0.31 -0.86 4.11 14.48 7.22 -0.80 5.05 5.18 11.75 1.39 -0.30 4.46 5.94 16.95 6.23
Nucleus -0.85 -15.81 2.00 2.59 14.57 0.20 -17.09 11.61 10.96 25.83 -0.87 -22.65 12.32 15.06 30.87
Peroxisomes -4.31 3.68 4.29 12.59 2.39 -9.11 8.98 6.00 13.04 -5.15 -9.36 9.71 6.33 15.69 -5.17
Vacuole 6.61 0.81 -2.92 -5.58 -3.36 -2.15 -8.12 -6.50 -4.48 0.13 0.93 -5.78 -3.81 -4.99 0.94
Vacuole Periphery -0.19 2.40 2.21 8.71 -1.63 -5.01 9.38 -1.36 1.67 -3.86 -4.15 8.33 -1.20 0.64 -3.85
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit
Localization
Cell Percentages cell periphery (67%)
Cell Cycle Regulation No
Subcompartmental Group cell periphery-3

Mrpl6

Mrpl6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrpl6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available