Standard name
Human Ortholog
Description Protein required for proper cell fusion and cell morphology; forms a complex with Bud14p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.4 0.31 0.48 0.56 0.34 0.34 0.34 0.25 0.3 0.27 0.3 0.19 0.6 0.52 0.58 0.36 0.3 0.41 0.26 0.16 0.25 0.07 0.08 0.15
Bud 0.24 0 0.3 0.29 0.36 0.24 0.27 0.23 0.24 0.21 0.23 0.24 0.22 0.22 0.18 0.27 0.23 0.24 0.44 0.49 0.38 0.51 0.51 0.54
Bud Neck 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0.17 0.17 0.18 0.33 0.31 0.18
Bud Site 0.26 0.19 0.31 0.25 0.18 0.14 0.12 0.09 0.12 0.09 0.09 0.08 0.22 0.07 0.05 0.12 0.1 0.08 – – – – – –
Cell Periphery 0.07 0 0.05 0.15 0 0.05 0.08 0.07 0.14 0.13 0.16 0.12 0.17 0.26 0.36 0.05 0.08 0.09 0.06 0.05 0 0 0 0
Cytoplasm 0.13 0.31 0.14 0.1 0.16 0.16 0.14 0.13 0.1 0.1 0.11 0.07 0.15 0.22 0.25 0.27 0.25 0.21 0 0.05 0 0 0 0
Endoplasmic Reticulum 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.13 0.38 0.54 0.41 0.22 0.34 0.42 0.49 0.58 0.52 0.54 0.6 0.2 0.13 0.21 0.16 0.09 0.08 0 0 0.05 0 0 0
Nucleus 0 0 0.07 0 0.07 0.05 0 0 0 0.05 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0.06 0.05 0 0 0 0.06 0.09 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.11 0.06 0 0.13 0.09 0.12 0.11 0.09 0.12 0.12 0.11 0.1 0.25 0.17 0.14 0.08 0.1 0.12 0 0 0 0 0 0
SpindlePole 0.11 0 0 0.05 0.11 0.06 0.05 0.05 0 0 0 0.05 0 0 0 0.08 0.14 0.14 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 135 5 56 134 119 92 145 132 102 109 82 71 97 163 213 95 44 95 109 10 34 8 20 44
Bud 82 0 35 69 127 64 115 118 80 83 64 91 35 68 67 70 33 55 183 34 51 63 129 165
Bud Neck 5 1 2 2 7 10 5 15 9 11 6 6 0 0 0 4 11 4 70 11 25 41 79 53
Bud Site 87 3 36 59 62 39 52 45 39 38 25 28 36 23 17 33 14 18 – – – – – –
Cell Periphery 25 0 6 37 14 14 35 39 48 52 44 43 27 83 133 13 12 20 23 3 4 0 2 2
Cytoplasm 44 5 16 25 55 43 60 70 34 42 29 27 24 71 90 71 37 50 3 3 4 2 2 10
Endoplasmic Reticulum 2 1 2 5 9 6 9 13 7 7 10 10 4 8 14 9 5 13 2 1 3 0 1 4
Endosome 10 0 1 1 10 6 10 6 2 2 2 5 0 3 0 5 2 7 2 1 0 0 2 3
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 2 6 6 1 0 0 0 0 1
Mitochondria 45 6 63 99 79 93 182 257 197 209 148 223 32 41 76 41 13 18 8 0 6 1 1 4
Nucleus 15 0 8 5 26 13 19 18 9 20 12 16 3 11 2 15 4 6 0 0 0 0 1 1
Nuclear Periphery 2 1 0 0 2 1 2 5 1 2 3 2 0 0 0 0 1 0 2 0 0 0 0 1
Nucleolus 14 1 6 1 10 12 27 47 15 21 12 16 0 3 1 2 4 7 0 0 0 0 0 0
Peroxisomes 39 1 4 32 32 32 49 49 41 49 29 38 41 53 50 22 14 27 2 0 1 0 1 0
SpindlePole 38 0 5 13 37 16 20 28 9 12 8 18 5 11 6 21 20 32 4 0 1 3 2 3
Vac/Vac Membrane 4 1 0 1 7 3 9 18 5 16 5 11 0 0 0 4 7 7 1 0 2 1 4 5
Unique Cell Count 341 16 116 240 352 271 429 523 338 402 273 372 162 316 365 264 146 233 421 70 138 126 252 305
Labelled Cell Count 547 25 240 483 596 444 739 860 598 673 479 605 305 539 670 407 227 365 421 70 138 126 252 305


Ambiguous, Bud, Bud Neck, Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.3 6.8 5.4 5.8 6.2 6.3 6.1 6.3 6.1 5.9 6.1 5.5 8.5 8.3 7.6 10.0 10.9 11.7 8.2 7.6 7.9
Std Deviation (1e-4) 2.7 1.2 1.1 1.4 1.9 1.9 1.8 1.9 2.0 1.7 2.0 1.5 1.9 2.2 2.2 3.6 3.7 4.5 2.1 2.0 2.0
Intensity Change (Log2) – – – 0.11 0.22 0.23 0.19 0.23 0.18 0.15 0.19 0.02 0.66 0.62 0.49 0.9 1.02 1.12 0.61 0.5 0.55


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.3 -2.8 -2.7 -2.9 -4.9 -3.5 -4.3 -3.4 -6.3 1.9 0.6 1.9 -2.3 -3.0 -1.3
Bud -0.3 1.2 -1.4 -0.7 -1.7 -1.4 -2.2 -1.4 -1.2 -1.6 -1.9 -2.7 -0.7 -1.4 -1.3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 2.2 0
Bud Site -1.3 -3.1 -3.8 -4.9 -6.6 -4.9 -5.9 -5.4 -6.5 -1.7 -6.4 -7.9 -4.3 -4.4 -5.7
Cell Periphery 2.8 0 0 1.1 0.9 2.6 2.3 3.0 2.0 2.9 4.8 6.5 -0.1 1.0 1.1
Cytoplasm -0.9 0.5 0.5 0.1 -0.1 -1.1 -1.0 -0.9 -2.2 0.2 2.0 2.5 2.8 2.3 1.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -2.3 -6.5 -3.7 -2.3 -1.0 0.7 -0.4 0 1.1 -6.0 -8.9 -6.9 -7.8 -8.0 -9.7
Nucleus 0 0.2 -0.8 -1.1 0 0 -0.8 -1.0 -1.1 0 -1.5 0 -0.5 -1.6 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 -0.3 0.4 1.3 -0.3 0 -0.3 -0.4 0 0 0 0 0 0
Peroxisomes 2.9 2.0 2.6 2.6 2.1 2.7 2.7 2.3 2.3 4.9 3.6 3.0 1.7 2.0 2.5
SpindlePole 0.4 2.0 0.6 0.2 0.5 0 0 0 0.2 0 0 0 1.3 2.6 2.7
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.7687 4.2383 4.4435 4.6471 4.4379 5.8221 6.4479 5.5882 5.3414 5.3988 5.5507 6.4568 3.8251 2.4978 3.2642 4.4915 3.265 3.8289
Actin 0.2414 0.0873 0.0288 0.2029 0.2245 0.16 0.1991 0.0415 0.0433 0.0869 0.0651 0.187 0.1628 0.0594 0.0272 0.1573 0.1293 0.1735
Bud 0.0382 0.0853 0.3779 0.089 0.105 0.0092 0.0456 0.0908 0.3696 0.0982 0.1302 0.0202 0.0494 0.1407 0.3914 0.1254 0.0996 0.0195
Bud Neck 0.1415 0.0223 0.0025 0.0016 0.1339 0.704 0.0574 0.0072 0.0126 0.061 0.0385 0.6284 0.1014 0.0034 0.0088 0.0093 0.0044 0.6376
Bud Periphery 0.0719 0.0744 0.429 0.6093 0.4992 0.0399 0.1007 0.0582 0.4118 0.6036 0.4791 0.0808 0.1244 0.1376 0.418 0.6615 0.6394 0.0911
Bud Site 0.3658 0.5901 0.1457 0.0694 0.0131 0.0295 0.2699 0.7273 0.0737 0.0128 0.0263 0.0206 0.3396 0.6333 0.1166 0.0232 0.0167 0.0216
Cell Periphery 0.0596 0.0217 0.0082 0.0181 0.0153 0.021 0.0845 0.0071 0.0075 0.018 0.0075 0.0146 0.1094 0.0087 0.0112 0.0144 0.0275 0.0261
Cytoplasm 0.0139 0.0789 0.0023 0.0026 0.0039 0.0084 0.0101 0.0427 0.0028 0.0055 0.0026 0.0084 0.0234 0.0037 0.0073 0.0015 0.005 0.0122
Cytoplasmic Foci 0.0225 0.0036 0.0004 0.0001 0.0002 0.0122 0.0377 0.0155 0.0113 0.0347 0.0168 0.0094 0.0051 0.0013 0.0012 0.0003 0.0069 0.005
Eisosomes 0.0197 0.0029 0.0001 0.0012 0.0007 0.004 0.0144 0.0002 0.0011 0.0011 0.0004 0.0017 0.0315 0.0006 0.0004 0.001 0.0011 0.001
Endoplasmic Reticulum 0.0008 0.0051 0.0003 0.0006 0.0006 0.0003 0.0126 0.0002 0.0013 0.0037 0.002 0.0012 0.001 0.0003 0.0006 0.0005 0.0007 0.0004
Endosome 0.0006 0.0019 0.0001 0.0001 0.0002 0.0008 0.0357 0.0033 0.0099 0.0329 0.0503 0.0041 0.008 0.0001 0.0004 0.0001 0.0076 0.0015
Golgi 0.0018 0.0009 0.0001 0.0003 0.0006 0.0029 0.0191 0.001 0.0074 0.0062 0.0302 0.0042 0.0015 0.0002 0.0006 0.0003 0.0024 0.0019
Lipid Particles 0.0017 0.0006 0.0001 0.0001 0.0001 0.001 0.0189 0.0002 0.0059 0.006 0.0372 0.0039 0.0026 0.0001 0.0006 0.0001 0.0068 0.0007
Mitochondria 0.0011 0.001 0.001 0.0016 0.0006 0.0006 0.024 0.0002 0.0186 0.0076 0.0549 0.0045 0.005 0.0006 0.0092 0.002 0.0062 0.0003
None 0.0092 0.0079 0.0008 0.0005 0.0002 0.0003 0.0051 0.0006 0.0013 0.0021 0.0015 0.0006 0.0094 0.0009 0.001 0.0006 0.0049 0.0002
Nuclear Periphery 0.0003 0.0012 0.0002 0.0003 0.0004 0.0001 0.0126 0.0001 0.0015 0.0038 0.0037 0.0007 0.0061 0.0003 0.0005 0.0003 0.0023 0.0002
Nucleolus 0.0011 0.0013 0.0003 0.0001 0.0002 0.0015 0.0012 0.0003 0.0034 0.0004 0.0091 0.0005 0.0008 0.0015 0.0001 0.0001 0.0019 0.0003
Nucleus 0.001 0.0025 0.0006 0.0003 0.0002 0.0006 0.0037 0.0007 0.0075 0.0012 0.0058 0.0021 0.002 0.0014 0.0003 0.0003 0.0039 0.0005
Peroxisomes 0.0039 0.0009 0.0001 0.0001 0.0001 0.0017 0.0209 0.0003 0.0048 0.0037 0.0127 0.0033 0.0074 0.0003 0.0034 0.0007 0.0149 0.0024
Punctate Nuclear 0.0017 0.0019 0.0003 0.0001 0.0001 0.0003 0.0174 0.0005 0.0023 0.0044 0.0017 0.002 0.0027 0.0031 0.0001 0 0.0158 0.0022
Vacuole 0.0022 0.0078 0.0012 0.0013 0.0008 0.0014 0.0072 0.0019 0.0019 0.0047 0.0182 0.0015 0.0052 0.0023 0.0007 0.0011 0.0023 0.0018
Vacuole Periphery 0.0001 0.0006 0.0001 0.0002 0.0001 0.0001 0.0025 0.0001 0.0006 0.0016 0.0062 0.0003 0.0012 0.0002 0.0003 0.0002 0.0004 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 26.046 25.4002 16.9633 23.5561 27.4252 28.3981 22.6859 22.245 23.1731 31.7734
Translational Efficiency 1.5149 0.8652 0.9537 0.8997 0.9479 1.1757 0.8087 0.7881 0.8042 0.9562

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1699 74 172 928 1264 1746 1512 406 2963 1820 1684 1334

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 734.34 952.46 1304.85 1119.36 815.42 891.98 1111.67 1111.73 768.93 894.44 1131.40 1117.04
Standard Deviation 107.81 184.89 186.25 157.71 152.55 154.71 160.10 183.12 134.90 156.51 173.15 165.89
Intensity Change Log 2 — 0.375210 0.829364 0.608154 — 0.129468 0.447113 0.447191 — 0.251138 0.640886 0.525704

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.089611 0.096036 0.312867* 0.122602* 0.112490* 0.032584 0.056369 0.055179 0.099371 0.035164 0.082567 0.102082*
Bud Neck 0.130756 0.127252 0.076881 0.038550 0.129645 0.162315 0.071623 0.034797 0.130282 0.160889 0.072160 0.037408
Bud Site 0.586348* 0.591798* 0.433604* 0.682327* 0.529540* 0.650081* 0.776221* 0.727163* 0.562114* 0.647711* 0.741227* 0.695973*
Cell Periphery 0.058846 0.047078 0.041545 0.016418 0.125218* 0.110072* 0.016291 0.013991 0.087160 0.107511* 0.018871 0.015680
Cytoplasm 0.062810 0.048399 0.026599 0.082564 0.040923 0.023656 0.048697 0.097712 0.053473 0.024662 0.046440 0.087175
Cytoplasmic Foci 0.013975 0.024076 0.009710 0.008353 0.010189 0.004194 0.006529 0.017128 0.012360 0.005003 0.006854 0.011024
Eisosomes 0.002829 0.013943 0.015449 0.002828 0.005802 0.001569 0.001299 0.000917 0.004098 0.002072 0.002744 0.002247
Endoplasmic Reticulum 0.001855 0.004620 0.006442 0.001154 0.003240 0.000783 0.000679 0.000790 0.002446 0.000939 0.001267 0.001043
Endosome 0.009235 0.006379 0.007627 0.006486 0.008324 0.003037 0.001263 0.010096 0.008846 0.003173 0.001913 0.007585
Golgi 0.006517 0.005764 0.002233 0.004587 0.006341 0.001888 0.000722 0.004217 0.006442 0.002046 0.000876 0.004475
Lipid Particles 0.002541 0.001879 0.002813 0.001814 0.002357 0.000142 0.000745 0.002602 0.002463 0.000213 0.000956 0.002054
Mitochondria 0.012925 0.004797 0.001146 0.004595 0.011119 0.004438 0.001328 0.001963 0.012154 0.004453 0.001309 0.003794
Mitotic Spindle 0.000693 0.000579 0.000820 0.006560 0.000410 0.000734 0.001716 0.002464 0.000572 0.000728 0.001624 0.005313
None 0.001936 0.000081 0.000042 0.000090 0.000642 0.000095 0.000090 0.000091 0.001384 0.000094 0.000085 0.000090
Nuclear Periphery 0.000025 0.000015 0.000109 0.000120 0.000012 0.000005 0.000020 0.000091 0.000019 0.000006 0.000029 0.000111
Nuclear Periphery Foci 0.000119 0.000265 0.001495 0.000320 0.000160 0.000060 0.000233 0.000200 0.000136 0.000068 0.000362 0.000283
Nucleolus 0.000192 0.000043 0.000044 0.000065 0.000062 0.000012 0.000039 0.000033 0.000137 0.000013 0.000040 0.000055
Nucleus 0.001466 0.001224 0.006856 0.000823 0.000748 0.000328 0.001425 0.001373 0.001160 0.000365 0.001980 0.000991
Peroxisomes 0.011873 0.019572 0.002031 0.004570 0.008113 0.001234 0.002494 0.004553 0.010269 0.001979 0.002447 0.004565
Vacuole 0.004849 0.005861 0.051289 0.013343 0.003991 0.002339 0.012054 0.021783 0.004483 0.002482 0.016062 0.015911
Vacuole Periphery 0.000597 0.000339 0.000402 0.001831 0.000674 0.000433 0.000163 0.002858 0.000630 0.000429 0.000187 0.002144

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.30 -7.37 -3.17 -1.08 6.04 11.87* 7.61 5.92 -2.55 0.24 13.77* 3.25 -0.05 -9.50 -2.59
Bud Neck 0.14 4.78 15.56 3.34 2.78 -3.97 8.38 13.74 19.59 7.36 -4.56 11.47 20.43 20.86 8.08
Bud Site -0.12 6.20 -6.27 -1.94 -8.82 -9.85 -19.36 -9.09 -2.97 3.36 -8.94 -16.93 -10.75 -2.90 3.81
Cell Periphery 0.81 2.67 11.47 2.14 2.96 1.92 17.12 16.21 16.96 0.81 -3.56 19.12 19.66 18.58 1.38
Cytoplasm 0.97 2.95 -4.13 -2.81 -5.40 4.68 -2.85 -6.61 -8.38 -5.36 9.38 0.24 -7.71 -13.01 -7.37
Cytoplasmic Foci -1.10 0.88 2.96 1.65 0.94 4.51 2.18 -2.07 -3.77 -2.93 6.01 3.93 0.53 -4.08 -2.48
Eisosomes -1.74 -3.61 0.09 1.75 3.56 7.24 7.58 8.20 3.04 1.57 4.58 3.06 3.09 -0.19 0.63
Endoplasmic Reticulum -0.86 -4.20 1.29 1.07 4.76 3.32 3.45 3.33 0.01 -0.21 3.40 2.39 3.06 -0.34 1.21
Endosome 1.25 0.26 1.60 -0.00 0.68 4.11 5.84 -0.58 -2.90 -3.71 5.90 7.70 0.99 -3.21 -4.22
Golgi 0.33 4.50 1.49 0.53 -1.99 4.06 5.54 1.53 -1.70 -2.80 5.61 8.38 2.01 -2.43 -4.09
Lipid Particles 0.49 -1.00 0.95 0.04 1.80 4.40 2.67 -0.21 -2.39 -1.66 5.94 3.02 0.66 -3.81 -1.77
Mitochondria 2.55 8.13 4.38 0.10 -2.47 4.57 7.18 6.33 2.78 -0.69 6.57 10.40 6.24 0.67 -2.36
Mitotic Spindle 0.51 -1.26 -3.47 -3.52 -3.09 -2.12 -3.94 -2.75 -2.29 -0.51 -1.00 -3.67 -3.94 -3.80 -2.71
None 3.01 3.05 2.99 -0.32 -1.02 4.14 3.98 4.09 -0.16 0.55 3.61 3.57 3.60 -0.11 0.38
Nuclear Periphery 0.60 -3.64 -1.68 -1.92 1.63 4.47 -3.71 -1.52 -1.63 -1.18 1.50 -2.82 -2.20 -2.57 -1.42
Nuclear Periphery Foci -1.29 -4.80 -1.46 -0.40 4.21 3.65 -1.29 -1.15 -3.17 0.62 3.23 -3.68 -1.58 -2.21 1.52
Nucleolus 1.13 0.96 0.93 -0.44 0.04 2.05 0.43 1.03 -1.70 0.85 1.65 1.12 1.00 -1.42 -0.12
Nucleus 0.32 -2.85 1.20 0.29 2.94 3.20 -4.60 -1.98 -2.86 0.90 4.31 -4.10 -0.50 -4.98 3.89
Peroxisomes -1.00 7.18 4.88 1.98 -2.97 6.00 4.43 2.50 -3.25 -1.72 8.50 7.55 5.38 -3.55 -2.60
Vacuole -0.47 -5.41 -5.19 -3.49 4.61 2.13 -5.96 -5.19 -5.53 -2.38 3.71 -7.83 -7.37 -8.32 1.17
Vacuole Periphery 1.29 0.78 -2.10 -2.47 -2.30 0.91 2.05 -1.30 -1.46 -1.63 1.26 3.37 -2.31 -2.64 -3.05
Standard name
Human Ortholog
Description Protein required for proper cell fusion and cell morphology; forms a complex with Bud14p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
Localization
Cell Percentages actin (22%), bud neck (9%), mixed (23%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Kel1

Kel1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kel1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available