Standard name
Human Ortholog
Description 6-phosphogluconolactonase; catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p; SOL3 has a paralog, SOL4, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.97 0.97 0.96 0.92 0.88 0.81 0.73 0.79 0.8 0.74 0.72 0.99 1.0 0.99 0.97 0.97 0.98 0.96 0.94 0.96 0.98 0.96 0.96
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.08 0.06 0.09 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.05 0.09 0.1 0.14 0.22 0.11 0.11 0.16 0.17 0 0 0 0 0 0.05 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 0 1 0 1 1 4 3 3 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1 6 2 2 1 0 0 0 0 0 0 0 1 1 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 3 6 3 6 10 9 13 9 15 6 16 2 0 0 2 2 2 0 0 0 0 0 0
Cytoplasm 141 160 496 282 423 502 489 483 396 298 287 400 220 266 317 179 146 179 140 159 481 166 243 188
Endoplasmic Reticulum 0 2 1 1 4 10 19 21 19 13 12 15 1 0 0 9 10 8 0 0 3 0 0 1
Endosome 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0
Golgi 0 0 1 0 0 1 1 1 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0
Mitochondria 1 1 0 0 1 3 7 4 38 24 35 43 0 0 0 1 2 0 1 1 1 0 0 0
Nucleus 0 0 5 2 2 3 12 25 10 10 7 20 2 0 0 0 1 1 0 2 2 0 3 3
Nuclear Periphery 0 0 0 0 0 0 0 1 1 2 0 1 0 0 0 0 0 0 1 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 2 11 16 40 60 84 148 57 40 63 94 3 0 5 2 3 9 0 2 0 0 2 0
Unique Cell Count 142 165 509 295 462 572 601 665 501 374 390 556 223 266 319 184 151 183 147 169 500 170 254 197
Labelled Cell Count 143 169 520 305 476 590 622 699 537 408 415 593 228 266 323 194 164 200 147 169 500 170 254 197


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 18.3 12.5 16.0 14.9 14.0 12.1 11.4 11.3 10.0 10.1 9.8 9.5 16.4 15.9 15.3 23.2 27.3 31.2 15.6 15.1 14.1
Std Deviation (1e-4) 3.6 2.8 2.8 2.8 2.3 2.2 2.0 2.1 2.1 2.2 2.1 2.1 3.5 3.3 3.1 7.7 9.1 10.6 3.1 2.9 3.0
Intensity Change (Log2) – – – -0.1 -0.19 -0.4 -0.48 -0.51 -0.68 -0.66 -0.71 -0.75 0.04 -0.01 -0.07 0.54 0.77 0.96 -0.04 -0.08 -0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0.2 0.8 0.5 1.0 0.8 2.7 0.5 1.9 0 0 0 0 0 0
Cytoplasm -1.4 -4.1 -6.0 -8.4 -11.3 -9.1 -8.7 -10.6 -11.4 1.0 2.6 2.0 -0.1 -0.5 0.3
Endoplasmic Reticulum 0 0 2.5 3.7 3.7 4.1 3.9 3.6 3.4 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 6.3 5.8 6.9 6.4 0 0 0 0 0 0
Nucleus 0 0 0 1.4 3.0 1.3 1.9 1.1 2.8 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.5 4.5 5.5 7.0 10.0 5.8 5.4 7.6 8.1 0 0 -0.6 0 0 1.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 19.3509 22.7225 20.9771 19.1235 19.1347 21.6322 13.6233 22.6208 20.7677 18.396 17.3834 19.8429 15.4295 21.3478 17.7851 17.2722 17.8704 18.8542
Actin 0.0223 0.0002 0.0117 0.0072 0.0481 0.0002 0.0372 0.0001 0.0005 0.0029 0.0055 0.0071 0.0179 0.0002 0.0112 0.0017 0.0011 0.0026
Bud 0.0004 0 0.0002 0.0002 0.0031 0.0001 0.001 0 0.0001 0.0001 0.0001 0.0001 0.0003 0 0.0008 0.0001 0.0006 0.0004
Bud Neck 0.0004 0.0002 0.0009 0.0005 0.008 0.001 0.0028 0.0001 0.0002 0.0003 0.0005 0.0006 0.0004 0.0001 0.0003 0.0003 0.0004 0.0009
Bud Periphery 0.0005 0 0.0001 0.0002 0.006 0 0.0009 0 0 0.0001 0.0001 0.0001 0.0001 0 0.0004 0.0001 0.0004 0.0004
Bud Site 0.0031 0.0001 0.0011 0.0003 0.0054 0 0.0075 0 0.0001 0.0001 0.0009 0.0002 0.0006 0 0.0004 0.0001 0.0007 0.0001
Cell Periphery 0.0001 0 0 0 0.0008 0 0.0002 0 0 0 0.0002 0 0 0 0.0001 0 0.0001 0.0001
Cytoplasm 0.8944 0.9912 0.9411 0.9073 0.8027 0.9759 0.609 0.9961 0.9726 0.8681 0.8821 0.9525 0.902 0.9955 0.8985 0.8818 0.9757 0.9626
Cytoplasmic Foci 0.0073 0.0003 0.0045 0.026 0.0176 0.0006 0.074 0.0003 0.009 0.033 0.0461 0.0052 0.0208 0.0002 0.0085 0.0031 0.0023 0.0014
Eisosomes 0.0003 0 0.0001 0.0002 0.0002 0 0.0002 0 0 0 0.0001 0 0 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0035 0.0004 0.0021 0.0005 0.0016 0.0018 0.0081 0.0001 0.0003 0.0022 0.0071 0.0004 0.0036 0.0001 0.0078 0.0005 0.0044 0.0066
Endosome 0.0114 0.0001 0.0082 0.0026 0.0178 0.0004 0.06 0 0.0069 0.0336 0.0083 0.0024 0.0122 0 0.0234 0.0512 0.0026 0.0093
Golgi 0.0029 0 0.0052 0.0018 0.0053 0 0.0188 0 0.0023 0.0107 0.0026 0.0036 0.0047 0 0.0052 0.0064 0.0004 0.0025
Lipid Particles 0.0042 0 0.0007 0.0015 0.0031 0 0.0224 0 0.0012 0.0343 0.025 0.004 0.0027 0 0.0021 0.0089 0.0001 0
Mitochondria 0.0054 0 0.0024 0.0332 0.0074 0.0001 0.0063 0 0.0001 0.0011 0.0016 0.0012 0.0014 0 0.0161 0.0354 0.0009 0.0039
None 0.0115 0.0003 0.0029 0.0004 0.002 0.0003 0.0105 0.0004 0.0004 0.0013 0.0088 0.0004 0.0027 0.0003 0.0035 0.0003 0.0015 0.0004
Nuclear Periphery 0.0051 0.0009 0.0019 0.0011 0.0045 0.0029 0.0668 0.0003 0.0006 0.0009 0.0011 0.001 0.0044 0.0003 0.0059 0.0008 0.0016 0.0013
Nucleolus 0.0004 0 0.0015 0 0.0009 0 0.0007 0 0 0 0.0002 0 0.0001 0 0.0001 0.0001 0 0
Nucleus 0.0206 0.0061 0.0098 0.0105 0.0173 0.0158 0.0189 0.0023 0.0048 0.006 0.004 0.015 0.0144 0.003 0.0089 0.0059 0.0056 0.0064
Peroxisomes 0.0018 0 0.0027 0.0041 0.0036 0 0.0242 0 0.0006 0.0034 0.002 0.0056 0.0016 0 0.0012 0.0009 0.0001 0
Punctate Nuclear 0.0032 0.0001 0.0019 0.0019 0.0276 0.0002 0.0248 0.0001 0.0002 0.0011 0.0023 0.0003 0.009 0.0001 0.0037 0.0002 0.0003 0.0002
Vacuole 0.001 0.0001 0.0007 0.0002 0.0152 0.0006 0.0022 0 0.0001 0.0005 0.0009 0.0002 0.0006 0 0.001 0.0009 0.0012 0.0005
Vacuole Periphery 0.0004 0 0.0002 0.0001 0.0018 0.0001 0.0037 0 0 0.0003 0.0003 0.0001 0.0003 0 0.0007 0.0012 0.0002 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 119.9033 98.6376 139.5554 107.5903 96.3279 110.2794 121.6735 103.2127 128.1317 90.7313
Translational Efficiency 0.8133 0.8878 0.6499 0.937 0.7805 0.7747 0.8817 0.9891 0.8558 0.8278

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2305 587 2111 1673 2780 2083 308 1804 5085 2670 2419 3477

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1194.88 1384.58 1233.55 1215.10 1190.47 1534.69 1288.86 1271.96 1192.47 1501.69 1240.59 1244.60
Standard Deviation 205.64 300.22 200.61 217.03 187.13 261.09 187.42 214.39 195.75 277.24 199.83 217.53
Intensity Change Log 2 — 0.212583 0.045950 0.024209 — 0.366416 0.114564 0.095522 — 0.291407 0.080602 0.060240

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000103 0.000259 0.000167 0.001449 0.000096 0.000166 0.003405 0.001878 0.000099 0.000186 0.000579 0.001672
Bud Neck 0.000683 0.000451 0.001513 0.005035 0.001003 0.000657 0.003135 0.001561 0.000858 0.000611 0.001719 0.003233
Bud Site 0.001690 0.002872 0.004834 0.024024 0.001760 0.003166 0.018749 0.009009 0.001729 0.003102 0.006605 0.016233
Cell Periphery 0.000036 0.000110 0.000060 0.000146 0.000032 0.000042 0.000249 0.000063 0.000034 0.000057 0.000084 0.000103
Cytoplasm 0.828702 0.866913 0.681914 0.624810 0.827839 0.872179 0.509524 0.761801 0.828230 0.871021 0.659964 0.695886
Cytoplasmic Foci 0.017156 0.013235 0.004795 0.018648 0.020621 0.018976 0.011693 0.010226 0.019050 0.017714 0.005674 0.014279
Eisosomes 0.000005 0.000003 0.000008 0.000016 0.000004 0.000003 0.000054 0.000006 0.000004 0.000003 0.000014 0.000011
Endoplasmic Reticulum 0.000922 0.000328 0.000798 0.001476 0.000709 0.000312 0.004194 0.000250 0.000806 0.000316 0.001230 0.000840
Endosome 0.000951 0.000533 0.000918 0.012092 0.000997 0.001247 0.008516 0.003316 0.000976 0.001090 0.001885 0.007538
Golgi 0.000329 0.001019 0.000163 0.010916 0.000401 0.001791 0.002354 0.002492 0.000368 0.001622 0.000442 0.006545
Lipid Particles 0.000266 0.000254 0.000363 0.000851 0.000347 0.000660 0.001831 0.000346 0.000310 0.000571 0.000550 0.000589
Mitochondria 0.000162 0.000045 0.000355 0.002407 0.000324 0.000126 0.001115 0.000514 0.000250 0.000108 0.000451 0.001425
Mitotic Spindle 0.000634 0.000941 0.006996 0.089707 0.001662 0.010035 0.005238 0.020270 0.001196 0.008036 0.006772 0.053681
None 0.005761 0.008818 0.007942 0.007155 0.005610 0.007689 0.010458 0.008401 0.005678 0.007937 0.008263 0.007801
Nuclear Periphery 0.000166 0.000056 0.000627 0.000674 0.000197 0.000075 0.001288 0.000275 0.000183 0.000071 0.000712 0.000467
Nuclear Periphery Foci 0.001162 0.003593 0.001129 0.002390 0.001159 0.001857 0.008464 0.001642 0.001160 0.002238 0.002063 0.002002
Nucleolus 0.000186 0.000159 0.000144 0.000664 0.000168 0.000099 0.000460 0.000160 0.000176 0.000112 0.000184 0.000403
Nucleus 0.102828 0.088597 0.240207 0.090917 0.112009 0.068736 0.187024 0.129841 0.107847 0.073103 0.233436 0.111112
Peroxisomes 0.000137 0.000162 0.000125 0.001646 0.000161 0.000229 0.000313 0.000711 0.000150 0.000214 0.000149 0.001161
Vacuole 0.037843 0.011550 0.046815 0.099110 0.024614 0.011566 0.221240 0.044193 0.030611 0.011562 0.069023 0.070617
Vacuole Periphery 0.000280 0.000103 0.000128 0.005867 0.000287 0.000388 0.000696 0.003044 0.000284 0.000326 0.000200 0.004402

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.33 -2.20 -2.96 -1.53 -2.21 -2.57 -2.66 -1.58 -1.28 1.45 -3.85 -3.63 -2.78 -2.10 -1.12
Bud Neck 0.76 -9.28 -7.81 -7.68 -2.08 2.05 -8.21 -4.06 -6.46 6.38 1.95 -10.09 -8.49 -9.78 1.05
Bud Site -4.24 -3.54 -7.79 -5.65 -4.31 -3.65 -4.22 -5.82 -3.34 2.35 -5.00 -4.90 -9.69 -6.54 -2.67
Cell Periphery -4.24 -10.01 -4.08 1.81 -0.95 -4.51 -9.38 -13.11 -7.65 7.36 -5.60 -13.98 -7.48 -1.83 1.95
Cytoplasm -5.07 34.84 33.85 32.22 3.39 -9.06 29.78 27.72 33.50 -17.34 -10.96 44.60 43.30 48.54 -6.44
Cytoplasmic Foci 1.08 14.05 8.30 3.79 -6.54 0.47 7.45 10.02 8.66 0.87 0.29 19.12 13.01 9.68 -7.98
Eisosomes 1.70 -10.70 -14.54 -14.06 -4.32 1.05 -12.72 -16.41 -17.67 10.71 2.86 -16.99 -21.13 -23.27 4.60
Endoplasmic Reticulum 2.10 -0.42 0.86 -2.49 2.71 2.85 -7.61 4.15 -0.11 9.21 3.17 -3.32 2.33 -1.67 8.75
Endosome 1.86 0.22 -3.25 -4.17 -3.51 -0.72 -4.58 -0.25 0.29 4.23 -0.31 -2.34 -2.85 -2.37 -1.55
Golgi -1.01 1.48 -2.69 -1.27 -3.07 -2.34 -0.56 -0.66 1.80 0.03 -2.60 1.50 -2.66 0.43 -3.28
Lipid Particles -1.56 -7.18 -13.45 -10.21 -8.59 -1.61 -13.07 -9.46 -0.33 9.98 -1.83 -12.27 -16.28 -1.54 -2.61
Mitochondria 3.76 -6.13 -3.08 -3.81 -1.54 1.34 -0.82 0.24 -3.51 1.40 1.71 -2.02 -1.93 -4.37 -0.53
Mitotic Spindle -1.06 -7.38 -9.39 -9.27 -5.55 -5.01 -3.74 -6.59 -1.03 -1.40 -5.37 -7.53 -11.37 -5.77 -4.90
None -2.62 -3.83 -1.84 1.71 2.35 -3.61 -0.84 -4.82 -0.70 -1.28 -4.38 -5.05 -4.51 0.90 0.92
Nuclear Periphery 7.28 -21.19 -19.48 -22.50 -1.35 6.50 -17.19 -17.00 -25.31 12.75 8.72 -25.45 -25.13 -30.84 6.29
Nuclear Periphery Foci -6.27 -0.96 -2.69 5.39 -1.46 -3.40 -8.47 -2.83 1.23 7.74 -6.15 -5.37 -3.79 3.94 2.70
Nucleolus 0.82 -0.02 -3.44 -3.33 -4.03 4.11 -3.06 -1.16 -2.81 2.38 3.51 -2.27 -3.30 -5.54 -1.71
Nucleus 2.97 -33.62 -8.40 -8.83 24.78 16.07 -10.99 -11.06 -24.02 6.94 15.63 -35.90 -13.68 -26.12 25.97
Peroxisomes 0.00 0.37 -2.44 -2.05 -2.61 -0.81 -0.95 -0.54 -0.01 0.03 -0.92 0.34 -2.06 -1.45 -2.24
Vacuole 7.97 -11.46 -28.01 -31.70 -18.70 5.80 -18.71 -24.34 -27.08 10.48 11.10 -20.60 -36.76 -42.16 -11.31
Vacuole Periphery 3.04 2.82 -2.38 -2.92 -2.85 -0.30 0.03 -1.14 -0.84 -1.14 -0.09 3.22 -2.46 -2.06 -3.08
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description 6-phosphogluconolactonase; catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p; SOL3 has a paralog, SOL4, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (98%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Sol3

Sol3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sol3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available