Standard name
Human Ortholog
Description Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.12 0.11 0.24 0.09 0.08 0.07 0.05 0 – 0 0 0.05 0.1 0.07 0.05 0.27 0.28 0.27 0.05 0.08 0.11 0.19 0.19 0.16
Bud 0 0 0.05 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.09 0.06 0.06 0.05 0.05 – 0.06 0.06 0.06 0 0 0.07 0.16 0.17 0.21 0 0 0 0 0 0
Cytoplasm 0.23 0.27 0.18 0.35 0.3 0.37 0.29 0.39 – 0.28 0.29 0.26 0.15 0.21 0.28 0.34 0.39 0.32 0 0.06 0 0 0 0
Endoplasmic Reticulum 0.74 0.67 0.6 0.5 0.54 0.31 0.37 0.18 – 0.35 0.27 0.31 0.79 0.78 0.7 0 0 0 0.77 0.73 0.72 0.33 0.34 0.41
Endosome 0 0 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.12 0.1 0.08 0 0 0.05 0.27 0.25 0.26
Mitochondria 0 0 0.13 0.14 0.17 0.34 0.41 0.33 – 0.43 0.43 0.48 0 0 0 0.06 0.08 0.07 0 0 0 0.07 0.06 0.05
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.06 0 0 0.06 0.05 0.08 0.14 – 0.1 0.1 0.06 0 0 0 0.09 0.09 0.14 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 25 40 77 19 29 23 18 10 – 12 9 19 43 29 23 54 40 32 12 35 41 57 76 62
Bud 2 5 15 0 9 11 9 13 – 10 15 8 6 2 1 7 6 4 3 5 0 2 3 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 2 4 2 1 1 0
Bud Site 0 0 0 0 0 1 0 0 – 0 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 8 9 18 24 20 21 16 – 23 19 24 17 16 33 31 24 25 0 1 2 0 0 0
Cytoplasm 47 100 57 74 111 130 112 128 – 116 95 108 62 88 142 67 56 38 7 28 7 4 6 7
Endoplasmic Reticulum 154 249 190 104 203 107 143 58 – 145 90 132 331 323 352 8 5 5 188 314 272 101 135 160
Endosome 1 4 16 4 11 7 3 14 – 7 6 4 5 1 2 3 3 4 7 8 8 22 27 17
Golgi 5 4 5 1 1 0 0 0 – 0 0 0 3 3 1 24 15 10 7 11 17 83 97 100
Mitochondria 2 4 42 30 63 117 159 107 – 176 143 201 1 0 0 11 11 8 6 10 12 21 22 18
Nucleus 1 0 0 0 0 0 0 3 – 1 1 2 0 0 0 0 0 1 0 0 0 0 0 0
Nuclear Periphery 1 0 2 0 0 0 3 1 – 7 6 2 1 0 0 1 0 0 0 0 1 0 0 1
Nucleolus 0 0 1 0 0 1 0 1 – 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 1 0 1 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 2 2 2
SpindlePole 0 0 1 0 0 0 0 0 – 0 0 1 1 4 4 10 1 2 1 0 0 1 1 0
Vac/Vac Membrane 7 22 3 7 21 18 32 46 – 40 32 27 4 2 15 17 13 17 5 9 4 5 12 13
Unique Cell Count 207 371 316 209 376 349 385 328 410 330 422 419 415 502 197 145 119 246 434 376 305 392 393
Labelled Cell Count 248 436 419 257 473 435 500 397 538 417 530 474 468 573 233 175 146 246 434 376 305 392 393


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.9 9.9 7.8 8.0 7.4 6.8 6.4 6.9 – 6.5 6.6 6.5 10.3 9.9 10.0 10.8 11.3 11.0 11.7 11.8 12.0
Std Deviation (1e-4) 1.4 1.3 1.2 1.6 1.3 1.3 1.4 1.4 – 1.2 1.2 1.3 1.2 1.1 1.2 1.8 2.2 1.7 1.7 1.6 1.5
Intensity Change (Log2) – – – 0.04 -0.08 -0.18 -0.27 -0.17 – -0.27 -0.25 -0.26 0.41 0.34 0.36 0.47 0.54 0.5 0.59 0.6 0.62

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -4.4 -6.1 -6.4 -7.6 -7.9 – -8.7 -8.1 -7.9 -5.1 -6.6 -8.4 0.8 0.7 0.5
Bud -3.2 -1.7 -1.1 -1.7 -0.5 – -1.7 -0.1 -2.2 -2.7 -3.8 -4.6 -0.6 -0.3 -0.6
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 2.9 2.2 1.8 1.7 1.3 – 1.8 1.8 1.8 0.9 0.7 2.4 5.3 5.3 6.3
Cytoplasm 4.5 3.5 5.5 3.4 5.9 – 3.2 3.2 2.4 -1.2 1.1 3.3 4.1 4.8 3.1
Endoplasmic Reticulum -2.3 -1.6 -7.6 -6.1 -11.1 – -6.6 -8.4 -7.8 5.6 5.2 2.9 -12.7 -11.4 -10.5
Endosome -1.8 -1.4 -2.2 -3.5 -0.5 – -2.6 -2.3 -3.4 -3.1 -4.3 -4.4 -2.1 -1.5 -0.8
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 5.1 4.3 0
Mitochondria 0.3 1.3 6.1 8.2 5.8 – 8.6 8.4 9.8 -7.5 -7.6 -8.4 -2.8 -1.8 -1.9
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 0 3.3 3.1 4.5 6.3 – 5.0 4.9 3.7 0 0 1.9 4.4 4.4 5.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.5686 5.8751 5.4971 5.2869 4.9683 5.4626 7.7299 8.2227 7.9023 8.1667 7.4847 8.2073 6.3997 6.7499 6.4646 6.1222 6.0673 6.4014
Actin 0.0249 0.0201 0.051 0.0216 0.0169 0.0189 0.0426 0.0221 0.0227 0.0095 0.0247 0.0195 0.078 0.0188 0.03 0.0219 0.0105 0.0094
Bud 0.0015 0.0007 0.0016 0.0008 0.0029 0.0014 0.0002 0.0004 0.0003 0.001 0.0002 0.0015 0.0008 0.0003 0.0027 0.0003 0.0001 0.0002
Bud Neck 0.0051 0.0009 0.0022 0.0074 0.0083 0.0075 0.0006 0.001 0.0008 0.0483 0.0009 0.0044 0.002 0.0008 0.003 0.001 0.0008 0.0027
Bud Periphery 0.0015 0.001 0.0024 0.0017 0.0036 0.0026 0.0002 0.0003 0.0004 0.0025 0.0004 0.0014 0.0013 0.0004 0.0021 0.0005 0.0003 0.0003
Bud Site 0.0082 0.0091 0.0067 0.0098 0.0195 0.0025 0.0007 0.0042 0.0013 0.0007 0.0003 0.0009 0.0085 0.0164 0.0031 0.0009 0.0002 0.0002
Cell Periphery 0.0014 0.0019 0.0017 0.0021 0.0009 0.0012 0.0019 0.0024 0.0032 0.0034 0.0018 0.0022 0.0022 0.0021 0.0022 0.0031 0.0014 0.0007
Cytoplasm 0.0788 0.2046 0.1722 0.1694 0.1869 0.192 0.0891 0.1001 0.1108 0.2046 0.0806 0.1421 0.083 0.2369 0.1799 0.1436 0.1002 0.1618
Cytoplasmic Foci 0.0546 0.0586 0.0628 0.0498 0.0957 0.0367 0.0412 0.0498 0.0394 0.0556 0.0561 0.036 0.0264 0.0473 0.0472 0.0268 0.043 0.0352
Eisosomes 0.0004 0.0002 0.0006 0.0028 0.0002 0.0002 0.0005 0.0004 0.0004 0.0001 0.0004 0.0002 0.0012 0.0002 0.0002 0.0004 0.0002 0.0001
Endoplasmic Reticulum 0.4455 0.3972 0.3587 0.43 0.2753 0.4731 0.5263 0.4927 0.5094 0.3699 0.3518 0.5222 0.5465 0.4484 0.4612 0.4685 0.5317 0.556
Endosome 0.162 0.1671 0.1595 0.1569 0.1969 0.1315 0.1033 0.1212 0.0974 0.1219 0.1382 0.1244 0.0921 0.1104 0.1168 0.1532 0.1177 0.119
Golgi 0.0856 0.087 0.0998 0.0738 0.1178 0.0738 0.124 0.1519 0.1706 0.1602 0.2382 0.0852 0.0427 0.0536 0.0792 0.0863 0.0899 0.0657
Lipid Particles 0.0398 0.0248 0.0262 0.0134 0.0354 0.0164 0.0446 0.0324 0.0248 0.0042 0.0811 0.0172 0.0394 0.0384 0.0314 0.0428 0.0401 0.0153
Mitochondria 0.0258 0.0057 0.024 0.0157 0.0114 0.0133 0.0043 0.006 0.0058 0.0065 0.0134 0.0104 0.0115 0.0016 0.0118 0.0131 0.0366 0.0054
None 0.0111 0.0028 0.0051 0.0038 0.0036 0.0041 0.0036 0.0014 0.0019 0.0014 0.0031 0.0171 0.0078 0.0035 0.0095 0.0022 0.0016 0.0028
Nuclear Periphery 0.019 0.0065 0.0098 0.0085 0.005 0.0094 0.0094 0.0049 0.0044 0.0026 0.0034 0.0057 0.025 0.0113 0.0099 0.0159 0.0154 0.01
Nucleolus 0.0012 0.0001 0.0001 0.0108 0.0009 0.0004 0 0.0001 0 0.0001 0 0.0001 0.0028 0.0001 0.0001 0.0002 0.0001 0.0001
Nucleus 0.0055 0.0012 0.0012 0.0054 0.0015 0.0049 0.0009 0.0005 0.0004 0.0005 0.0003 0.0013 0.007 0.0015 0.001 0.0013 0.0011 0.008
Peroxisomes 0.0082 0.0009 0.0066 0.0016 0.0078 0.0013 0.0011 0.001 0.0015 0.0008 0.0009 0.001 0.0073 0.0009 0.0019 0.0049 0.0023 0.0009
Punctate Nuclear 0.0039 0.0007 0.001 0.0012 0.0024 0.0013 0.0006 0.0005 0.0004 0.0004 0.0007 0.0007 0.0051 0.0015 0.0008 0.0034 0.001 0.0017
Vacuole 0.0116 0.0071 0.0047 0.0109 0.005 0.0053 0.0037 0.0052 0.003 0.0039 0.0021 0.0048 0.0064 0.0048 0.0044 0.007 0.0036 0.0032
Vacuole Periphery 0.0043 0.0017 0.0022 0.0023 0.002 0.0022 0.0012 0.0013 0.0011 0.0017 0.0013 0.002 0.0031 0.001 0.0018 0.0028 0.0022 0.0014

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.3193 38.7659 39.42 47.9783 31.2361 24.0785 42.8254 49.9701 41.9389 53.3683
Translational Efficiency 1.1574 0.761 0.8869 0.5932 0.9876 1.7063 0.8279 0.6883 0.8219 0.6891

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
360 1272 2237 1688 1523 2112 720 1235 1883 3384 2957 2923

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 743.00 997.22 1250.24 1484.89 889.22 996.53 1348.08 1447.88 861.27 996.79 1274.06 1469.25
Standard Deviation 106.44 154.18 166.17 233.88 438.83 146.27 179.56 232.20 401.53 149.30 174.65 233.89
Intensity Change Log 2 — 0.424550 0.750771 0.998922 — 0.164373 0.600294 0.703330 — 0.288649 0.670744 0.845428

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.014204 0.006688 0.013627 0.011659 0.003344 0.009678 0.017378 0.013974 0.005420 0.008554 0.014540 0.012637
Bud Neck 0.001693 0.000623 0.001393 0.002568 0.001678 0.001321 0.001754 0.001592 0.001681 0.001059 0.001481 0.002155
Bud Site 0.009079 0.007386 0.010771 0.023552 0.021978 0.006642 0.017480 0.017948 0.019512 0.006922 0.012404 0.021184
Cell Periphery 0.009138 0.001268 0.002022 0.008974 0.022581 0.002130 0.004554 0.016366 0.020011 0.001806 0.002639 0.012097
Cytoplasm 0.051029 0.049010 0.037549 0.030179 0.074920 0.062701 0.014657 0.021413 0.070352 0.057555 0.031975 0.026475
Cytoplasmic Foci 0.091430 0.181741 0.042175 0.077214 0.154341 0.122224 0.054458 0.054401 0.142313 0.144595 0.045166 0.067576
Eisosomes 0.003260 0.001027 0.000738 0.000744 0.001313 0.001648 0.000646 0.001127 0.001685 0.001414 0.000715 0.000906
Endoplasmic Reticulum 0.478161 0.411920 0.644103 0.334887 0.312581 0.374970 0.578326 0.437284 0.344237 0.388859 0.628087 0.378151
Endosome 0.031380 0.050382 0.040908 0.068882 0.046424 0.049581 0.064176 0.039302 0.043548 0.049882 0.046573 0.056384
Golgi 0.133321 0.175775 0.051084 0.092768 0.192977 0.171748 0.063632 0.058176 0.181571 0.173261 0.054139 0.078152
Lipid Particles 0.083959 0.077808 0.135711 0.297071 0.119512 0.154237 0.151942 0.313256 0.112715 0.125508 0.139663 0.303910
Mitochondria 0.030769 0.007453 0.000658 0.001172 0.011732 0.008042 0.000452 0.000858 0.015372 0.007821 0.000608 0.001039
Mitotic Spindle 0.000214 0.001311 0.000978 0.004859 0.000363 0.000672 0.001496 0.000740 0.000334 0.000912 0.001104 0.003119
None 0.000581 0.001832 0.001843 0.000247 0.002346 0.002825 0.000451 0.000750 0.002009 0.002452 0.001504 0.000460
Nuclear Periphery 0.000263 0.000331 0.000118 0.000264 0.000231 0.000250 0.000128 0.000353 0.000237 0.000280 0.000120 0.000301
Nuclear Periphery Foci 0.001910 0.004876 0.006303 0.010520 0.005348 0.003723 0.005307 0.003130 0.004691 0.004157 0.006060 0.007398
Nucleolus 0.000497 0.000055 0.000009 0.000023 0.000227 0.000093 0.000007 0.000014 0.000279 0.000079 0.000008 0.000019
Nucleus 0.004518 0.000547 0.000424 0.000487 0.002856 0.000896 0.000186 0.000264 0.003174 0.000765 0.000366 0.000393
Peroxisomes 0.046745 0.008161 0.002904 0.003706 0.011506 0.016972 0.002738 0.006472 0.018243 0.013660 0.002864 0.004874
Vacuole 0.002228 0.006459 0.005838 0.026095 0.008158 0.005823 0.017700 0.009845 0.007024 0.006062 0.008726 0.019230
Vacuole Periphery 0.005621 0.005347 0.000846 0.004129 0.005584 0.003824 0.002532 0.002736 0.005591 0.004397 0.001256 0.003540

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.63 0.17 0.77 -3.78 1.04 -6.01 -5.08 -6.25 -2.31 1.02 -3.41 -6.87 -6.40 -3.64 1.15
Bud Neck 1.97 0.50 -1.86 -8.72 -4.54 1.16 -0.35 0.18 -1.14 0.58 2.44 0.67 -2.20 -6.19 -3.58
Bud Site 0.93 -0.94 -5.88 -7.93 -6.16 5.64 1.24 1.18 -6.36 -0.17 5.67 3.01 -0.86 -10.25 -5.74
Cell Periphery 5.70 5.15 0.17 -10.92 -9.82 6.34 5.57 1.83 -11.15 -8.98 6.95 6.65 2.97 -14.75 -13.98
Cytoplasm 0.46 3.18 4.45 5.67 2.38 3.51 18.91 15.44 13.94 -2.71 4.51 14.13 15.25 13.83 2.47
Cytoplasmic Foci -10.29 6.70 1.87 17.73 -10.17 6.24 17.71 19.64 15.63 0.02 -0.51 24.39 17.82 22.04 -8.25
Eisosomes 5.06 5.97 5.98 1.88 -0.04 -2.15 4.77 1.32 4.01 -4.30 1.81 7.13 5.84 5.34 -2.61
Endoplasmic Reticulum 3.08 -8.08 7.03 6.30 28.74 -5.62 -16.93 -9.61 -4.93 8.45 -4.59 -28.49 -3.14 1.50 28.05
Endosome -5.55 -3.09 -10.43 -6.47 -10.95 -1.30 -5.08 2.87 4.47 7.29 -3.16 -1.62 -6.03 -3.49 -5.11
Golgi -4.09 8.95 4.27 13.35 -10.21 3.28 20.45 23.08 22.86 1.16 1.49 26.69 20.51 24.03 -7.94
Lipid Particles 0.80 -6.36 -21.40 -28.14 -19.56 -5.75 -3.72 -20.49 -16.72 -14.07 -2.69 -5.21 -29.13 -28.66 -24.94
Mitochondria 5.83 7.74 7.59 6.66 -2.16 2.93 10.36 9.71 10.44 -1.42 5.91 12.68 12.18 12.28 -2.35
Mitotic Spindle -1.88 -3.19 -5.66 -3.72 -4.65 -2.49 -2.30 -1.92 -0.37 1.46 -2.46 -3.56 -5.77 -4.30 -3.95
None -1.92 -2.66 1.67 2.55 3.71 -0.63 4.75 2.89 2.86 -0.66 -0.76 1.24 4.44 4.23 2.79
Nuclear Periphery -0.79 3.68 -0.28 0.66 -5.30 -0.45 3.33 -0.57 -0.48 -1.03 -1.03 5.10 -0.76 -0.29 -2.02
Nuclear Periphery Foci -3.06 -8.18 -8.84 -4.54 -4.18 2.08 -0.05 2.61 0.85 3.03 0.78 -2.17 -3.69 -4.73 -2.16
Nucleolus 1.28 1.41 1.36 1.61 -2.99 1.46 2.60 2.51 2.09 -1.15 2.05 2.85 2.72 2.35 -2.98
Nucleus 1.56 1.60 1.55 -0.15 -1.28 3.43 4.61 4.48 7.16 -1.16 3.63 4.19 4.10 4.53 -0.96
Peroxisomes 7.86 9.02 8.85 5.32 -1.58 -3.55 7.28 4.04 8.09 -4.27 3.03 11.56 9.93 10.53 -4.45
Vacuole -5.18 -7.32 -14.07 -11.08 -12.04 2.95 -4.29 -1.64 -3.79 3.24 1.58 -2.27 -10.69 -11.82 -8.89
Vacuole Periphery 0.30 7.12 1.78 1.57 -6.57 4.14 5.49 4.25 1.68 -0.22 2.93 13.69 4.27 1.81 -5.76
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Integral membrane protein of the early Golgi apparatus and ER; involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
Localization
Cell Percentages ER (87%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Svp26

Svp26


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Svp26-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available