Standard name
Human Ortholog
Description Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0.08 – 0 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.99 0.97 0.95 0.88 0.79 – 0.77 0.66 0.75 0.67 0.98 0.99 0.99 0.98 0.99 0.99 0.96 0.94 0.93 0.89 0.89 0.91
Endoplasmic Reticulum 0 0 0 0 0 0.08 0.15 – 0.15 0.21 0.14 0.21 0 0 0 0 0.06 0.05 0 0 0 0 0.06 0.06
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0.05 0.12 0.09 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 6 5 – 6 16 10 16 0 0 0 0 1 0 0 0 1 0 1 0
Bud 0 0 0 1 1 6 1 – 0 2 0 1 1 0 1 0 0 0 0 0 0 2 3 3
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 3 7 8 32 – 11 23 7 14 4 2 10 3 3 2 0 0 0 0 0 0
Cytoplasm 315 118 196 277 311 251 337 – 207 244 138 187 327 445 531 203 226 204 296 105 180 130 312 322
Endoplasmic Reticulum 2 1 0 4 13 23 63 – 40 78 26 58 8 6 3 7 13 11 3 2 4 5 19 20
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Golgi 0 0 1 0 3 7 6 – 13 45 17 24 0 0 0 0 0 0 0 0 0 2 1 1
Mitochondria 0 0 0 0 0 2 0 – 2 1 1 6 0 0 0 1 0 2 0 0 0 1 4 0
Nucleus 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 – 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 2 2 1 3 – 1 2 0 1 0 0 2 0 0 2 0 1 2 0 1 1
Unique Cell Count 317 119 197 285 328 286 426 268 372 184 281 334 451 536 207 228 206 309 112 195 147 351 355
Labelled Cell Count 317 119 197 288 337 304 447 281 413 200 308 340 453 547 215 243 221 309 112 195 147 351 355


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 124.4 125.8 97.0 90.1 81.9 53.1 60.6 – 50.8 50.2 47.7 46.2 144.1 120.0 144.6 148.4 145.1 149.5 128.5 127.5 138.2
Std Deviation (1e-4) 24.0 23.6 18.9 21.4 17.9 17.0 15.2 – 13.1 12.1 13.5 11.9 24.5 25.3 25.3 44.5 46.9 43.9 25.4 32.4 35.9
Intensity Change (Log2) – – – -0.11 -0.24 -0.87 -0.68 – -0.93 -0.95 -1.02 -1.07 0.57 0.31 0.58 0.61 0.58 0.62 0.41 0.39 0.51

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 3.0 0 3.4 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 3.9 – 0 3.6 0 3.2 0 0 0 0 0 0
Cytoplasm -1.8 -2.9 -4.8 -6.7 – -7.0 -9.2 -7.3 -8.9 -1.5 -0.9 -0.6 -1.3 -0.5 -0.5
Endoplasmic Reticulum 0 0 4.1 5.7 – 5.7 6.9 5.5 6.8 0 0 0 0 3.4 3.3
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 2.7 4.8 4.0 3.9 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 77.7995 102.3133 91.122 87.283 81.9955 91.2113 104.3063 130.6514 123.1096 115.8477 116.2892 124.4623 93.5307 123.7187 115.5283 110.8974 114.8998 97.0828
Actin 0.0044 0.0003 0.0005 0.0001 0.019 0.0031 0.0012 0.0007 0.0005 0.0001 0.0005 0.0017 0.0026 0.0003 0.0003 0.0016 0.0001 0.0128
Bud 0.0013 0.0005 0.0008 0.0004 0.0008 0.0037 0.0011 0.0004 0.0007 0.0005 0.0007 0.0011 0.0019 0.0007 0.0009 0.0014 0.0007 0.0004
Bud Neck 0.0006 0.0007 0.0007 0.0004 0.0011 0.0026 0.0005 0.0004 0.0005 0.0004 0.0008 0.0011 0.0005 0.0002 0.0004 0.0004 0.0004 0.0007
Bud Periphery 0.0018 0.0003 0.0005 0.0001 0.0014 0.004 0.0013 0.0003 0.0004 0.0002 0.0002 0.0009 0.0019 0.0002 0.0003 0.0003 0.0001 0.0002
Bud Site 0.0005 0.0003 0.0003 0 0.0005 0.0006 0.0005 0.0003 0.0003 0.0001 0.0002 0.0002 0.0008 0.0005 0.0004 0.0004 0 0.0011
Cell Periphery 0.0151 0.0074 0.0072 0.0004 0.0011 0.0065 0.0211 0.0152 0.0095 0.0034 0.0014 0.0021 0.0061 0.0011 0.0027 0.0003 0.0004 0.0002
Cytoplasm 0.7198 0.9145 0.8719 0.896 0.7372 0.6631 0.7438 0.911 0.8753 0.6679 0.7982 0.7976 0.7988 0.97 0.91 0.8992 0.7785 0.8093
Cytoplasmic Foci 0.0031 0.0019 0.0025 0.0014 0.0046 0.0094 0.0036 0.0015 0.004 0.0015 0.0099 0.0072 0.0053 0.0014 0.0024 0.004 0.0187 0.0342
Eisosomes 0.0002 0 0 0 0.0002 0.0001 0.0008 0.0004 0 0 0.0004 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0636 0.0266 0.0218 0.0009 0.0898 0.0441 0.0454 0.0165 0.0153 0.0151 0.0122 0.0369 0.0288 0.0021 0.0025 0.0006 0.0014 0.0066
Endosome 0.0147 0.0057 0.0099 0.0049 0.0211 0.0474 0.0097 0.0028 0.0057 0.0079 0.0274 0.0382 0.0131 0.0025 0.0073 0.011 0.0612 0.0799
Golgi 0.0035 0.002 0.0015 0.0001 0.0045 0.028 0.0025 0.0013 0.0008 0.0002 0.0247 0.0117 0.002 0.0003 0.0012 0.0008 0.006 0.0267
Lipid Particles 0.0013 0.0007 0.0007 0 0.0049 0.0022 0.0019 0.0017 0.0011 0.0004 0.0032 0.0004 0.001 0 0.0004 0.0001 0.0003 0.0058
Mitochondria 0.008 0.0007 0.0009 0.0001 0.0044 0.0262 0.0139 0.0034 0.0008 0.0001 0.0094 0.0174 0.0061 0.0004 0.0084 0.0005 0.0007 0.0032
None 0.0015 0.0002 0.0003 0.0001 0.0005 0.0012 0.0019 0.0014 0.0008 0.0002 0.003 0.0013 0.0022 0.0002 0.0004 0.0002 0.0002 0.0006
Nuclear Periphery 0.0172 0.0028 0.0042 0.0021 0.0064 0.0183 0.0225 0.0042 0.0093 0.0059 0.0041 0.0048 0.0176 0.0008 0.0025 0.0016 0.0034 0.0025
Nucleolus 0.0032 0.0001 0.0002 0.0001 0.0001 0.0005 0.0033 0.0007 0.0004 0.0002 0.0108 0.0005 0.0011 0 0.0003 0.0001 0.0001 0.0001
Nucleus 0.0067 0.0011 0.0019 0.0017 0.0022 0.0038 0.0053 0.0016 0.0022 0.0025 0.0024 0.0032 0.0066 0.0008 0.0019 0.0017 0.0019 0.0007
Peroxisomes 0.0003 0 0 0 0.0023 0.0001 0.0002 0.0001 0.0001 0 0.0007 0.0001 0.0001 0 0 0.0001 0.0001 0.0044
Punctate Nuclear 0.0003 0 0 0 0.0004 0.0002 0.0041 0.0026 0.0002 0 0.0001 0.0001 0.0001 0 0 0 0 0.0019
Vacuole 0.104 0.0294 0.0623 0.0793 0.0748 0.1003 0.0889 0.0295 0.0609 0.2222 0.0677 0.049 0.0779 0.0161 0.0458 0.0584 0.0769 0.0058
Vacuole Periphery 0.0289 0.0048 0.0121 0.0119 0.0226 0.0345 0.0264 0.0041 0.0112 0.0711 0.0219 0.0244 0.0253 0.0022 0.0117 0.0172 0.0488 0.0031

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 790.2478 768.434 673.379 776.4329 829.755 846.5254 747.518 717.3605 709.0911 681.3787
Translational Efficiency 2.9092 2.9564 3.1234 2.5659 2.936 2.8726 2.4064 2.6801 2.5386 2.6782

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1887 323 158 106 1902 1965 275 1787 3789 2288 433 1893

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 6112.02 7995.17 10800.82 13298.44 6718.79 7347.80 10386.60 11536.96 6416.61 7439.19 10537.75 11635.60
Standard Deviation 1315.73 1619.82 1745.04 2407.15 1260.78 1497.34 2405.66 2593.74 1323.68 1531.91 2196.91 2615.19
Intensity Change Log 2 — 0.387479 0.821420 1.121536 — 0.129111 0.628450 0.779990 — 0.257966 0.723596 0.952786

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000024 0.000120 0.000107 0.000508 0.000031 0.000069 0.000143 0.000124 0.000027 0.000076 0.000130 0.000146
Bud Neck 0.000087 0.001105 0.005441 0.002644 0.000230 0.000170 0.003406 0.000668 0.000159 0.000302 0.004148 0.000779
Bud Site 0.001561 0.006273 0.002285 0.012712 0.001121 0.002689 0.004609 0.006259 0.001340 0.003195 0.003761 0.006620
Cell Periphery 0.007318 0.026712 0.020756 0.053569 0.005926 0.008668 0.029326 0.024986 0.006619 0.011216 0.026199 0.026586
Cytoplasm 0.699717 0.509235 0.087824 0.196293 0.611594 0.736323 0.291966 0.538803 0.655481 0.704265 0.217476 0.519624
Cytoplasmic Foci 0.009242 0.020171 0.024821 0.012497 0.012213 0.010681 0.025953 0.006580 0.010733 0.012021 0.025540 0.006912
Eisosomes 0.000001 0.000003 0.000008 0.000024 0.000001 0.000001 0.000010 0.000003 0.000001 0.000001 0.000009 0.000004
Endoplasmic Reticulum 0.000819 0.000513 0.000140 0.000835 0.000448 0.000556 0.000171 0.000453 0.000633 0.000550 0.000160 0.000475
Endosome 0.000527 0.001100 0.000755 0.001139 0.000529 0.000551 0.000747 0.000617 0.000528 0.000628 0.000750 0.000646
Golgi 0.061394 0.123165 0.073198 0.076165 0.104732 0.068709 0.069936 0.035167 0.083149 0.076397 0.071126 0.037463
Lipid Particles 0.005245 0.017142 0.014715 0.033075 0.004902 0.005341 0.018842 0.011347 0.005073 0.007007 0.017336 0.012564
Mitochondria 0.000251 0.000290 0.000157 0.000489 0.000181 0.000344 0.000150 0.000581 0.000216 0.000337 0.000153 0.000575
Mitotic Spindle 0.000499 0.002226 0.002488 0.001089 0.000937 0.001036 0.001305 0.000435 0.000719 0.001204 0.001737 0.000472
None 0.001781 0.002334 0.000729 0.000998 0.001843 0.001927 0.001422 0.001236 0.001812 0.001985 0.001169 0.001222
Nuclear Periphery 0.000333 0.000997 0.006873 0.001697 0.000658 0.000299 0.002911 0.000307 0.000496 0.000397 0.004357 0.000385
Nuclear Periphery Foci 0.008140 0.013185 0.017098 0.007843 0.011877 0.006681 0.014200 0.004002 0.010016 0.007599 0.015257 0.004217
Nucleolus 0.000063 0.000126 0.000278 0.000195 0.000062 0.000054 0.000331 0.000259 0.000062 0.000064 0.000312 0.000256
Nucleus 0.003037 0.007239 0.013402 0.009678 0.004286 0.004438 0.028485 0.008093 0.003664 0.004833 0.022981 0.008182
Peroxisomes 0.000023 0.000027 0.000017 0.000054 0.000007 0.000019 0.000029 0.000084 0.000015 0.000021 0.000024 0.000083
Vacuole 0.061630 0.132775 0.512859 0.415125 0.071240 0.053272 0.362069 0.257607 0.066454 0.064496 0.417092 0.266428
Vacuole Periphery 0.138308 0.135260 0.216050 0.173371 0.167184 0.098173 0.143988 0.102389 0.152803 0.103409 0.170283 0.106363

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.53 -6.82 -1.97 -1.65 -1.66 -2.30 -8.04 -4.78 -2.61 0.84 -3.43 -10.32 -5.09 -2.98 -0.71
Bud Neck -5.58 -7.83 -4.47 -2.71 3.16 1.96 -8.81 -6.27 -6.90 6.44 -4.03 -11.68 -7.88 -6.62 8.58
Bud Site -5.08 -1.62 -3.37 -2.05 -2.95 -5.86 -1.98 -9.23 -6.24 -0.96 -6.98 -2.27 -9.51 -6.04 -2.22
Cell Periphery -7.37 -6.10 -6.59 -3.41 -4.43 -4.00 -10.87 -13.60 -10.79 2.40 -6.60 -12.24 -14.49 -9.93 0.52
Cytoplasm 9.16 40.79 16.65 8.30 -4.13 -11.81 15.71 6.96 19.12 -11.73 -5.49 29.84 14.55 18.01 -18.67
Cytoplasmic Foci -5.37 -4.02 -2.21 2.65 3.01 1.75 -5.92 5.36 4.16 7.74 -1.86 -7.20 4.31 5.55 8.35
Eisosomes -4.79 -6.43 -2.11 -1.88 -1.40 -1.36 -6.50 -4.67 -4.06 4.54 -3.54 -8.62 -4.63 -3.82 4.02
Endoplasmic Reticulum 3.00 8.85 0.13 -0.63 -1.56 -1.79 7.66 0.38 2.14 -8.36 1.37 11.27 3.52 1.75 -8.08
Endosome -4.08 -3.33 -1.88 0.09 -0.87 -0.45 -1.84 -2.37 -1.72 0.86 -2.44 -3.02 -3.03 -0.65 1.20
Golgi -8.13 -1.65 -0.85 4.38 0.00 9.00 7.60 21.07 11.65 7.53 2.17 4.30 19.03 13.91 9.34
Lipid Particles -5.73 -7.81 -5.43 -2.65 -3.30 -0.67 -8.45 -7.68 -6.85 4.50 -3.55 -10.82 -9.08 -5.82 4.05
Mitochondria -0.62 1.59 -0.75 -0.58 -0.89 -2.03 0.15 -1.88 -1.23 -1.96 -2.01 1.12 -1.85 -1.30 -2.04
Mitotic Spindle -2.12 -2.87 -2.32 1.34 2.07 -0.41 -1.12 3.22 2.33 2.34 -2.22 -3.13 1.74 2.88 3.55
None -1.32 6.49 0.89 1.51 -0.67 -0.37 1.70 1.92 2.30 0.53 -0.91 4.17 2.27 2.71 -0.57
Nuclear Periphery -5.35 -7.03 -5.52 -2.19 5.58 7.07 -9.85 6.46 -1.15 11.45 2.62 -10.19 2.74 0.08 10.45
Nuclear Periphery Foci -3.61 -5.69 0.72 3.69 5.62 7.76 -1.81 13.04 5.97 10.27 4.61 -5.66 13.82 7.66 12.88
Nucleolus -2.54 -8.27 -5.73 -1.89 3.11 1.34 -2.58 -6.62 -6.87 0.31 -0.49 -3.91 -6.85 -6.74 0.44
Nucleus -2.67 -4.58 -2.54 -0.86 0.89 -0.18 -7.69 -6.58 -6.51 5.50 -2.38 -8.84 -7.79 -6.16 5.35
Peroxisomes -0.64 0.26 -1.75 -1.53 -1.94 -4.69 -3.11 -8.96 -7.11 -4.76 -1.47 -2.00 -7.65 -7.19 -5.82
Vacuole -6.90 -24.45 -13.99 -10.17 3.40 5.10 -19.07 -29.37 -32.52 5.84 0.43 -28.58 -33.37 -32.19 10.47
Vacuole Periphery 0.48 -4.93 -1.28 -1.42 2.03 12.17 3.35 12.98 0.33 3.76 11.23 -0.61 12.31 0.69 7.20
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Egd2

Egd2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Egd2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available