Standard name
Human Ortholog
Description Nuclear envelope protein; anchored to the nuclear inner membrane, that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0 0.05 0 0.05 0 0 0.06 0 0 0 0 0.06 0.1 0.15 0.06 0.07 0.06 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0
Endosome 0.16 0.2 0.16 0.28 0.19 0.08 0.14 0.3 0.15 0.24 0.11 0.13 0 0.12 0.13 0.3 0.34 0.36 0.13 0.17 0.12 0.13 0.13 0.08
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.08 0 0.06 0 0.09 0.18 0.17 0.05 0.14 0.09 0.17 0.13 0 0 0 0.07 0.05 0.06 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0.05 0.08 0.08 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07 0.06 0.49 0.5 0.4
Nucleolus 0.62 0.69 0.71 0.68 0.55 0.63 0.59 0.48 0.65 0.67 0.73 0.67 0.76 0.48 0.56 0.67 0.71 0.75 0 0.06 0 0 0 0
Peroxisomes 0.08 0 0.07 0.08 0.06 0 0 0.05 0 0.05 0 0 0 0 0 0.07 0 0.05 0 0 0 0 0 0
SpindlePole 0.67 0.65 0.7 0.74 0.59 0.46 0.44 0.45 0.53 0.58 0.54 0.55 0.88 0.83 0.68 0.65 0.53 0.64 0.69 0.6 0.67 0.27 0.1 0.08
Vac/Vac Membrane 0 0.11 0.06 0 0.08 0.07 0.05 0.08 0 0 0 0 0 0 0 0.09 0.09 0.05 0 0 0 0 0.12 0.21
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 1 0 2 0 6 8 16 9 20 9 30 21 0 1 0 1 0 0 0 3 1 0 5 10
Bud Neck 0 0 0 0 2 5 4 5 4 2 5 8 0 1 1 1 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 2 10 7 2 2 6 8 10 0 0 0 0 0 0
Cell Periphery 1 1 0 0 0 0 0 0 0 1 0 1 0 0 8 1 0 0 0 0 0 0 0 0
Cytoplasm 8 4 9 15 41 25 25 64 23 21 11 17 1 20 37 11 11 7 4 2 0 0 1 3
Endoplasmic Reticulum 0 1 1 1 0 2 1 0 0 1 1 0 0 1 1 2 1 1 0 2 5 1 3 7
Endosome 23 53 28 102 152 67 151 301 134 266 86 140 0 23 34 56 55 43 18 48 22 3 21 18
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Mitochondria 11 10 10 16 70 152 183 47 120 99 133 139 0 2 0 12 8 7 1 4 3 0 5 8
Nucleus 2 1 3 3 23 39 81 81 40 37 25 48 0 3 1 1 5 2 0 2 0 0 2 10
Nuclear Periphery 1 7 1 6 6 15 46 28 23 31 15 21 0 0 1 3 0 1 8 20 11 11 82 88
Nucleolus 90 186 124 249 448 518 628 483 576 757 589 736 13 92 141 123 117 89 4 16 3 0 3 5
Peroxisomes 12 1 12 28 47 9 30 52 37 51 18 36 0 3 5 12 6 6 0 0 0 0 0 1
SpindlePole 97 175 121 271 484 379 466 445 468 651 434 612 15 159 173 120 87 76 99 174 124 6 15 16
Vac/Vac Membrane 6 29 10 12 64 61 52 83 38 38 11 15 0 2 7 17 15 6 0 3 2 0 19 46
Unique Cell Count 145 270 174 368 819 827 1069 996 883 1130 806 1104 17 192 253 184 164 118 145 291 184 23 163 223
Labelled Cell Count 252 468 321 703 1345 1290 1690 1601 1485 1970 1366 1804 29 307 409 360 305 238 145 291 184 23 163 223


Nucleus, SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 8.1 6.4 6.4 6.2 5.6 5.2 6.4 5.7 6.0 5.7 5.8 6.1 7.5 7.9 8.7 8.4 9.0 8.6 8.8
Std Deviation (1e-4) 1.4 1.6 1.2 1.4 1.6 1.3 1.3 1.6 1.4 1.5 1.5 1.6 1.1 1.3 1.6 1.7 1.5 1.5 1.6 2.0
Intensity Change (Log2) -0.01 -0.05 -0.21 -0.32 -0.01 -0.17 -0.1 -0.17 -0.15 -0.06 0.22 0.3 0.43 0.39 0.49 0.42 0.45

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 1.7 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.6 -0.1 -1.4 0 0.6 -1.8 0 0 0 0 1.9 3.1 0.3 0.6 0.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 3.0 0.8 -3.3 -0.7 3.8 -0.3 2.2 -2.0 -1.2 0 -1.1 -0.8 3.2 3.7 4.0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.7 1.2 4.1 3.8 -0.6 2.9 1.3 3.6 2.6 0 -2.5 0 0.3 -0.4 0.1
Nucleus 0 0 1.8 2.9 3.0 1.7 1.1 0 1.6 0 0 0 0 0 0
Nuclear Periphery 0 0 0 2.4 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -0.8 -4.0 -2.2 -3.1 -5.5 -1.5 -1.1 0.5 -1.2 0.5 -4.5 -3.3 -0.9 0 0.8
Peroxisomes 0.3 -0.6 0 -2.8 -0.9 -1.6 -1.4 -3.2 -2.3 0 -2.6 -2.6 -0.1 -1.3 -0.6
SpindlePole 1.0 -2.6 -5.7 -6.4 -6.1 -4.0 -3.0 -3.8 -3.5 1.6 3.0 -0.3 -0.9 -3.1 -0.9
Vacuole -1.4 0.9 0.8 -0.5 1.2 -0.8 -1.6 0 0 0 -2.5 -1.5 1.3 1.2 -0.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.2088 4.4966 3.7335 3.2814 3.1266 3.8452 3.4838 5.5642 3.8568 3.8665 2.805 3.7707 2.4454 4.0979 3.1398 3.2177 2.3804 3.3601
Actin 0.0046 0.0001 0.0008 0.0012 0.0002 0 0.0013 0 0.0092 0.0018 0.0135 0.0022 0.0015 0 0.0001 0.0005 0.0001 0
Bud 0.0002 0.0001 0 0.0001 0 0 0 0 0 0 0.0001 0.0001 0.0001 0 0 0 0 0
Bud Neck 0.0009 0.0025 0.0009 0.0014 0.0001 0.0017 0.0002 0.001 0.0002 0.0009 0.0002 0.0003 0.001 0.0002 0.0002 0.0001 0.0001 0.0006
Bud Periphery 0.0002 0 0.0001 0.0004 0 0 0 0 0 0 0.0002 0.0001 0.0002 0 0 0 0 0
Bud Site 0.0007 0.0005 0.0004 0.0005 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0004 0.0002 0.003 0.0001 0.0001 0.0001 0 0
Cell Periphery 0.0002 0.0001 0.0002 0.0004 0 0.0001 0 0.0001 0 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0057 0.0026 0.0002 0.0021 0.0015 0.0001 0.001 0 0.0001 0.0011 0.0012 0.0051 0.0002 0 0.0001 0.0004 0.0001 0
Cytoplasmic Foci 0.092 0.0784 0.0458 0.0554 0.0314 0.0389 0.0663 0.0828 0.056 0.0924 0.0391 0.0463 0.0973 0.0771 0.0578 0.0708 0.0621 0.0643
Eisosomes 0.0001 0 0 0.0001 0 0 0 0 0.0001 0 0 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0024 0.0016 0.0002 0.0021 0.0007 0.0001 0.0001 0 0 0.0003 0.0016 0.0002 0.0008 0 0.0001 0.0023 0.0001 0
Endosome 0.0129 0.0027 0.0104 0.0108 0.0052 0.0012 0.0034 0.0007 0.0008 0.0043 0.0084 0.0037 0.0049 0.0007 0.0009 0.0105 0.0025 0.0008
Golgi 0.0052 0.0015 0.0067 0.0055 0.0037 0.0019 0.0035 0.0019 0.0018 0.0036 0.0046 0.0048 0.006 0.0023 0.0021 0.0036 0.0051 0.0025
Lipid Particles 0.1459 0.1136 0.1026 0.1419 0.0944 0.1154 0.1812 0.1699 0.1322 0.1334 0.0796 0.181 0.206 0.1877 0.1427 0.1802 0.2795 0.2102
Mitochondria 0.0101 0.0005 0.0042 0.0056 0.0033 0.0004 0.0001 0 0.0005 0.0001 0.0024 0.0101 0.0035 0 0.0001 0.0003 0 0
None 0.0047 0.0002 0.0002 0.0018 0.012 0.0001 0.0021 0 0.0001 0.0047 0.001 0.0041 0.0004 0 0.0001 0.0002 0.0001 0
Nuclear Periphery 0.0146 0.0102 0.0192 0.0638 0.0493 0.0044 0.0082 0.0016 0.0076 0.006 0.1193 0.012 0.0127 0.0036 0.0094 0.0501 0.0404 0.003
Nucleolus 0.118 0.2014 0.1488 0.1611 0.042 0.1705 0.052 0.1467 0.0543 0.0495 0.0154 0.0457 0.1264 0.1477 0.1292 0.0717 0.0271 0.0923
Nucleus 0.0131 0.0269 0.0158 0.0334 0.0058 0.0122 0.0056 0.0052 0.0109 0.0045 0.0022 0.0022 0.0058 0.0053 0.0055 0.004 0.0018 0.0045
Peroxisomes 0.0132 0.0008 0.002 0.0042 0.0175 0.0006 0.0022 0.0005 0.0016 0.0032 0.0075 0.0036 0.0028 0.0006 0.0007 0.0006 0.0009 0.0004
Punctate Nuclear 0.5523 0.5556 0.6375 0.4971 0.731 0.6514 0.6722 0.5892 0.7243 0.6935 0.6998 0.6776 0.5256 0.5745 0.6507 0.6027 0.5788 0.6211
Vacuole 0.0015 0.0005 0.0031 0.0065 0.0007 0.0003 0.0001 0.0002 0.0001 0.0001 0.0003 0.0003 0.0008 0.0001 0.0001 0.0006 0.0001 0.0001
Vacuole Periphery 0.0014 0.0004 0.001 0.0048 0.0011 0.0004 0.0001 0.0001 0.0001 0.0001 0.0031 0.0003 0.001 0.0001 0.0003 0.0013 0.0009 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.9935 6.1266 9.85 14.4695 17.7716 13.6993 13.9378 16.0268 20.9147 13.5422
Translational Efficiency 0.7005 1.0965 0.8227 0.9006 0.5117 0.8289 0.7372 0.762 0.6315 0.6536

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1644 1436 2716 1538 1620 877 2359 1586 3264 2313 5075 3124

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 754.48 849.17 1299.23 1008.98 804.12 769.92 925.80 952.64 779.12 819.12 1125.65 980.38
Standard Deviation 110.54 143.08 196.66 177.72 119.72 117.16 125.28 160.05 117.83 139.26 250.37 171.31
Intensity Change Log 2 0.170571 0.784102 0.419343 -0.062702 0.203290 0.244520 0.054932 0.513574 0.331795

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000113 0.000195 0.000161 0.000224 0.000063 0.000297 0.000058 0.000211 0.000088 0.000233 0.000113 0.000217
Bud Neck 0.002416 0.003425 0.004641 0.010106 0.002071 0.002268 0.004752 0.007832 0.002245 0.002987 0.004692 0.008951
Bud Site 0.001041 0.001232 0.000902 0.007040 0.001082 0.001292 0.002231 0.005652 0.001061 0.001255 0.001520 0.006335
Cell Periphery 0.000111 0.000140 0.000053 0.000094 0.000074 0.000122 0.000049 0.000101 0.000093 0.000133 0.000051 0.000097
Cytoplasm 0.002613 0.001226 0.000310 0.012545 0.001638 0.001399 0.006359 0.022745 0.002129 0.001291 0.003122 0.017723
Cytoplasmic Foci 0.020644 0.024705 0.019214 0.026566 0.018292 0.022611 0.014981 0.045255 0.019477 0.023911 0.017246 0.036054
Eisosomes 0.000129 0.000215 0.000294 0.000030 0.000165 0.000094 0.000024 0.000027 0.000147 0.000169 0.000169 0.000029
Endoplasmic Reticulum 0.002279 0.002685 0.000908 0.001931 0.001241 0.003336 0.000785 0.002447 0.001764 0.002931 0.000851 0.002193
Endosome 0.011269 0.011948 0.001557 0.025408 0.007307 0.013721 0.013181 0.044094 0.009302 0.012620 0.006960 0.034894
Golgi 0.002112 0.002763 0.000903 0.002929 0.001320 0.003550 0.000483 0.002353 0.001719 0.003061 0.000708 0.002637
Lipid Particles 0.027186 0.022772 0.009176 0.047110 0.027567 0.053710 0.009730 0.067708 0.027375 0.034503 0.009433 0.057567
Mitochondria 0.000898 0.001312 0.000841 0.001547 0.000808 0.002743 0.000329 0.001262 0.000853 0.001855 0.000603 0.001402
Mitotic Spindle 0.015539 0.039897 0.182110 0.393605 0.023315 0.033384 0.215437 0.281123 0.019398 0.037428 0.197601 0.336500
None 0.001318 0.000938 0.000265 0.000708 0.000782 0.001468 0.000448 0.000777 0.001052 0.001139 0.000350 0.000743
Nuclear Periphery 0.006518 0.006467 0.021011 0.028796 0.004980 0.008193 0.012710 0.017648 0.005754 0.007121 0.017153 0.023137
Nuclear Periphery Foci 0.835728 0.754665 0.307827 0.385426 0.836205 0.767589 0.674856 0.454824 0.835964 0.759565 0.478432 0.420658
Nucleolus 0.050449 0.086470 0.375557 0.023867 0.054320 0.060145 0.028773 0.015475 0.052370 0.076488 0.214362 0.019606
Nucleus 0.010057 0.020203 0.045975 0.012892 0.009185 0.013443 0.010052 0.012125 0.009624 0.017640 0.029277 0.012503
Peroxisomes 0.007589 0.014918 0.025015 0.002854 0.007695 0.008204 0.001663 0.003739 0.007641 0.012372 0.014161 0.003303
Vacuole 0.001752 0.003176 0.002550 0.013603 0.001692 0.002003 0.002906 0.012956 0.001722 0.002731 0.002715 0.013275
Vacuole Periphery 0.000243 0.000649 0.000731 0.002721 0.000200 0.000429 0.000193 0.001648 0.000222 0.000566 0.000481 0.002176

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.50 -2.41 -4.36 -1.91 -3.46 -3.99 -0.75 -4.34 0.73 -4.17 -4.96 -2.75 -6.08 -0.65 -5.26
Bud Neck -2.40 -6.64 -11.53 -10.13 -8.67 -0.55 -7.15 -10.60 -10.18 -4.34 -2.60 -9.83 -15.60 -13.81 -9.42
Bud Site -0.96 0.31 -7.70 -7.50 -7.81 -0.17 -4.64 -6.23 -5.77 -3.76 -0.60 -4.09 -9.90 -9.57 -8.46
Cell Periphery -0.78 2.78 0.32 1.29 -7.47 -2.69 2.15 -2.61 0.91 -6.07 -1.89 3.42 -0.92 1.53 -9.47
Cytoplasm 1.92 3.28 -8.01 -8.85 -9.23 0.61 -4.77 -9.99 -10.19 -7.36 1.98 -2.35 -12.79 -13.52 -11.72
Cytoplasmic Foci -1.34 0.79 -2.91 -1.56 -4.22 -1.43 0.83 -9.47 -6.98 -10.47 -2.07 1.11 -9.02 -6.48 -10.84
Eisosomes -4.56 -11.19 8.39 12.97 30.83 5.62 11.95 11.46 11.42 -2.44 -1.61 -1.78 14.02 15.26 27.51
Endoplasmic Reticulum -0.84 2.94 0.15 1.26 -3.71 -2.95 2.70 -2.88 0.92 -3.85 -3.06 3.62 -1.68 1.36 -5.30
Endosome -0.53 7.99 -7.76 -7.44 -15.89 -3.92 -6.42 -16.53 -11.81 -13.40 -3.06 2.21 -17.55 -14.24 -20.14
Golgi -1.33 5.01 -0.68 0.22 -3.02 -5.14 9.20 -1.61 2.34 -3.38 -4.30 7.59 -1.50 1.56 -4.45
Lipid Particles 1.72 8.45 -3.90 -5.42 -10.38 -5.91 7.74 -8.34 -1.30 -14.45 -3.14 11.45 -8.82 -5.63 -17.71
Mitochondria -1.06 0.20 -1.95 -0.72 -2.59 -1.67 0.73 -0.96 1.33 -4.86 -1.93 0.70 -1.88 0.80 -4.71
Mitotic Spindle -5.71 -29.69 -37.39 -33.45 -18.40 -1.41 -28.91 -28.28 -25.85 -4.05 -5.08 -41.08 -46.20 -41.58 -15.97
None 1.37 4.26 0.29 -1.11 -4.27 -1.13 0.89 -0.50 1.00 -3.49 -0.16 3.31 -0.14 0.04 -5.58
Nuclear Periphery -0.05 -11.31 -9.73 -10.52 -3.02 -1.59 -5.34 -7.54 -4.26 -3.33 -1.31 -12.03 -12.26 -10.87 -4.17
Nuclear Periphery Foci 7.82 60.49 43.35 32.61 -5.00 5.37 19.25 35.73 24.33 17.72 9.53 53.29 55.58 39.98 8.01
Nucleolus -6.79 -48.92 5.99 12.02 54.99 -0.83 5.36 9.34 7.93 5.73 -5.91 -34.88 10.89 14.93 44.91
Nucleus -5.15 -19.49 -4.90 -0.43 9.49 -2.29 -1.81 -3.67 -1.25 -2.09 -5.71 -16.35 -6.10 -0.62 6.87
Peroxisomes -5.07 -17.25 5.69 9.06 27.93 -0.52 8.62 4.76 4.75 -5.80 -4.85 -9.93 7.37 10.02 21.61
Vacuole -5.08 -4.56 -10.31 -9.58 -9.84 -1.47 -3.69 -9.55 -9.38 -8.11 -5.32 -5.11 -14.03 -13.29 -12.72
Vacuole Periphery -2.58 -7.50 -4.64 -3.63 -3.57 -2.91 -0.39 -3.97 -3.24 -3.95 -3.38 -6.59 -6.09 -4.67 -5.11
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Nuclear envelope protein; anchored to the nuclear inner membrane, that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)
Localization
Cell Percentages spindle pole (13%), nucleolus (8%), mixed (48%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Nvj1

Nvj1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Nvj1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available