Standard name
Human Ortholog
Description Basic leucine zipper (bZIP) transcription factor from ATF/CREB family involved in stress-responsive regulatory network; mediates transcriptional activation of NCE103 in response to low CO2 levels; proposed to be a regulator of oleate responsive genes; involved in utilization of non-optimal carbon sources and chromosome stability; relocalizes to the cytosol in response to hypoxia; CST6 has a paralog, ACA1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0.1 0.18 0.14 0 0.05 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0 0 0 0 0 0 0.06 0 0.12 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.96 0.96 1.0 0.94 0.93 0.92 0.93 0.89 0.86 0.88 0.84 0.87 0.89 0.83 0.82 0.88 0.87 0.85 0.92 0.95 0.91 0.95 0.89 0.83
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.05 0.05 0.11 0.16 0.1 0.19 0.22 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.07 0 0 0 0 0 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 3 2 2 0 2 0 0 0 0 0 0 1 2 1 1 1 0
Bud Neck 0 0 0 0 0 0 0 4 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 0 0 1 1 0 2 3 5 2 8 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Cytoplasm 3 11 0 11 18 13 20 22 2 15 8 8 9 31 35 14 11 13 0 1 0 1 0 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 5 1 6 0 0 0 0 0 0
Endosome 0 1 0 0 0 1 1 0 0 0 0 1 0 0 2 0 1 1 1 1 0 0 1 1
Golgi 0 0 0 2 0 0 0 0 0 1 0 0 0 0 0 1 0 0 3 0 0 0 1 0
Mitochondria 12 4 0 0 1 3 5 12 20 12 38 18 0 0 0 4 8 8 1 1 0 0 0 1
Nucleus 241 410 69 215 321 316 477 671 307 320 270 366 77 144 200 289 197 268 238 413 81 82 133 139
Nuclear Periphery 2 1 0 1 0 3 10 2 4 1 1 2 0 0 0 1 1 3 0 0 0 0 0 0
Nucleolus 11 1 1 0 3 17 24 86 58 38 61 91 0 1 5 8 6 14 2 2 0 0 0 4
Peroxisomes 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 0 1 0 3 0 1 1 1 1 1 2 0 1 1 1 0 0 0 1 1
Vac/Vac Membrane 1 8 0 0 4 6 7 8 8 3 2 4 1 0 2 16 10 22 7 8 3 0 5 12
Unique Cell Count 251 429 69 228 346 345 515 756 358 362 320 422 87 174 244 327 226 316 259 435 89 87 149 168
Labelled Cell Count 271 437 70 230 348 361 544 813 404 399 383 501 88 178 250 338 236 337 259 435 89 87 149 168


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 8.3 6.9 8.4 8.9 7.9 8.2 8.7 7.6 8.3 7.1 7.6 8.5 8.6 8.0 11.4 11.5 10.6 7.3 8.1 8.5
Std Deviation (1e-4) 1.5 1.4 1.3 2.1 1.6 1.7 1.6 1.7 1.8 2.0 1.8 1.8 1.6 1.9 1.9 2.6 3.1 3.2 1.4 1.6 1.5
Intensity Change (Log2) – – – 0.28 0.36 0.18 0.23 0.33 0.13 0.25 0.03 0.13 0.3 0.31 0.2 0.71 0.72 0.61 0.07 0.23 0.3

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 3.8 3.3 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 3.0 0 0 0 0 0 0 0
Nucleus -2.0 -2.3 -2.5 -2.3 -2.9 -3.3 -3.0 -3.5 -3.2 -2.9 -3.7 -3.8 -3.0 -3.1 -3.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 2.6 3.3 2.4 3.6 4.0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.7056 6.1159 6.2063 5.5773 5.2218 5.6392 4.3097 4.5277 4.0501 3.6183 3.1561 4.4385 3.8492 2.833 3.4435 3.3711 3.3328 3.4267
Actin 0 0 0 0 0 0 0.014 0 0.0176 0.0289 0.003 0.0018 0.035 0 0 0 0 0
Bud 0 0 0 0 0 0 0.0009 0 0.0004 0.0004 0.001 0.0002 0.0001 0.0001 0 0 0 0.0002
Bud Neck 0 0 0 0 0.0007 0.0002 0.0012 0.0001 0.0013 0.0188 0.0009 0.0009 0.0004 0.0001 0 0 0 0.0005
Bud Periphery 0 0 0.0001 0 0 0 0.0028 0 0.0005 0.0008 0.0035 0.0006 0.0001 0 0 0 0 0.0002
Bud Site 0 0 0 0 0 0 0.0061 0.0002 0.0038 0.0073 0.0013 0.0005 0.0002 0.0004 0 0 0 0.0004
Cell Periphery 0 0 0 0 0 0 0.0007 0 0.0003 0.0007 0.0009 0.0002 0.0001 0 0 0 0 0.0001
Cytoplasm 0.0004 0.0004 0 0 0 0.0001 0.0054 0.0031 0.006 0.0003 0.0032 0.0009 0.0018 0.0011 0 0 0 0.0001
Cytoplasmic Foci 0.0003 0 0 0 0 0.0001 0.0372 0.0001 0.0061 0.0271 0.0063 0.0027 0.0083 0.0001 0 0 0 0
Eisosomes 0 0 0 0 0 0 0.0004 0 0.0022 0.0003 0.0002 0.0001 0.0003 0 0 0 0 0
Endoplasmic Reticulum 0.0004 0 0 0 0 0 0.0035 0.0003 0.0026 0.0002 0.0026 0.0007 0.0024 0.0001 0 0 0 0
Endosome 0.0008 0 0 0 0 0.0004 0.0136 0.0011 0.0088 0.0015 0.009 0.0037 0.0047 0.0003 0 0 0 0
Golgi 0 0 0 0 0 0 0.0053 0 0.0062 0.0025 0.0013 0.0012 0.003 0 0 0 0 0
Lipid Particles 0.0003 0 0 0 0 0.0002 0.0258 0 0.0045 0.0026 0.0047 0.005 0.0151 0 0 0 0 0
Mitochondria 0.0001 0 0.0009 0 0.0001 0 0.011 0.0002 0.0119 0.0021 0.0359 0.0033 0.001 0.0002 0.0001 0 0 0.0001
None 0.0001 0 0 0 0 0.0001 0.008 0.0005 0.0033 0.0003 0.0084 0.0035 0.0017 0.0004 0 0 0 0
Nuclear Periphery 0.0016 0.0028 0.0012 0.0001 0.0004 0.0009 0.0143 0.0092 0.0033 0.0008 0.0297 0.0022 0.0027 0.008 0.0024 0.0001 0.0002 0.0001
Nucleolus 0.0087 0.0072 0.0049 0.0028 0.0409 0.0273 0.0131 0.0085 0.0052 0.0093 0.0655 0.0231 0.0099 0.0167 0.006 0.0026 0.0125 0.0403
Nucleus 0.9815 0.9887 0.9858 0.997 0.9575 0.9683 0.7879 0.9709 0.8976 0.8829 0.7763 0.9438 0.9029 0.9649 0.9913 0.9972 0.9869 0.9576
Peroxisomes 0 0 0 0 0 0 0.0122 0 0.0107 0.0113 0.0029 0.0005 0.0032 0 0 0 0 0
Punctate Nuclear 0.0053 0.0007 0.0051 0 0.0003 0.0021 0.0246 0.0011 0.004 0.0007 0.028 0.0034 0.0068 0.0038 0.0001 0 0.0002 0.0002
Vacuole 0.0003 0.0001 0.0006 0 0.0001 0.0001 0.0074 0.0037 0.0024 0.0008 0.0057 0.001 0.0002 0.003 0 0 0 0.0002
Vacuole Periphery 0.0001 0.0001 0.0011 0 0 0 0.0044 0.0009 0.001 0.0002 0.0098 0.0006 0.0002 0.0007 0 0 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 20.6419 13.9793 17.8419 26.9464 22.7081 24.3815 28.8342 37.2051 28.9818 27.735
Translational Efficiency 1.3402 1.759 1.52 1.045 1.0652 1.6485 1.2413 0.9992 1.4675 1.2775

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
700 1322 65 934 1333 1621 224 145 2033 2943 289 1079

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 693.24 769.77 1281.94 1037.97 856.03 866.17 1209.19 1156.56 799.98 822.87 1225.55 1053.91
Standard Deviation 84.76 177.87 154.19 155.19 116.73 131.25 154.98 149.29 131.87 161.24 157.75 159.62
Intensity Change Log 2 — 0.151073 0.886902 0.582338 — 0.016989 0.498308 0.434107 — 0.078531 0.685212 0.502323

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000068 0.000764 0.001352 0.001264 0.000296 0.000364 0.001029 0.001033 0.000217 0.000544 0.001102 0.001233
Bud Neck 0.000546 0.004845 0.009953 0.032303 0.004302 0.009935 0.011408 0.025723 0.003008 0.007648 0.011081 0.031418
Bud Site 0.000081 0.001149 0.001105 0.010339 0.000841 0.001735 0.001182 0.004943 0.000579 0.001472 0.001165 0.009614
Cell Periphery 0.000057 0.000302 0.000043 0.000215 0.000158 0.000291 0.000052 0.000154 0.000124 0.000296 0.000050 0.000207
Cytoplasm 0.003049 0.004775 0.000178 0.004551 0.005290 0.002338 0.000341 0.001953 0.004519 0.003432 0.000304 0.004202
Cytoplasmic Foci 0.000840 0.001019 0.000035 0.003803 0.001173 0.000584 0.000030 0.000093 0.001059 0.000779 0.000031 0.003304
Eisosomes 0.000008 0.000036 0.000060 0.000036 0.000025 0.000031 0.000052 0.000031 0.000019 0.000033 0.000054 0.000035
Endoplasmic Reticulum 0.001303 0.008354 0.002958 0.005686 0.003488 0.007841 0.003591 0.003898 0.002736 0.008071 0.003449 0.005446
Endosome 0.000140 0.000673 0.000067 0.007707 0.000894 0.001122 0.000094 0.000452 0.000634 0.000920 0.000088 0.006732
Golgi 0.000143 0.000812 0.000092 0.002534 0.000562 0.000311 0.000070 0.000081 0.000418 0.000536 0.000075 0.002204
Lipid Particles 0.000441 0.000382 0.000059 0.001467 0.000287 0.000542 0.000057 0.000237 0.000340 0.000470 0.000058 0.001302
Mitochondria 0.000600 0.002189 0.001638 0.012647 0.001081 0.002993 0.001293 0.001732 0.000916 0.002631 0.001371 0.011180
Mitotic Spindle 0.000026 0.002537 0.000182 0.027677 0.000766 0.002696 0.004623 0.006695 0.000511 0.002625 0.003624 0.024858
None 0.010100 0.023267 0.000782 0.003713 0.008370 0.003578 0.001085 0.001776 0.008966 0.012422 0.001017 0.003453
Nuclear Periphery 0.000217 0.000364 0.000105 0.003213 0.000350 0.000864 0.000203 0.000815 0.000304 0.000639 0.000181 0.002890
Nuclear Periphery Foci 0.000150 0.000701 0.000041 0.003043 0.000653 0.000367 0.000079 0.000379 0.000480 0.000517 0.000070 0.002685
Nucleolus 0.008136 0.013889 0.023257 0.004705 0.016810 0.007826 0.007600 0.002535 0.013824 0.010549 0.011121 0.004414
Nucleus 0.972582 0.930555 0.955873 0.857386 0.952512 0.951504 0.965482 0.945041 0.959423 0.942093 0.963321 0.869165
Peroxisomes 0.000163 0.001046 0.001293 0.000998 0.000531 0.000716 0.000475 0.000185 0.000404 0.000864 0.000659 0.000889
Vacuole 0.000441 0.001735 0.000767 0.011276 0.001299 0.003329 0.001141 0.002054 0.001004 0.002613 0.001057 0.010037
Vacuole Periphery 0.000910 0.000607 0.000159 0.005437 0.000312 0.001034 0.000115 0.000190 0.000518 0.000842 0.000125 0.004732

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.35 -9.81 -12.55 -2.51 -0.29 -1.18 -10.76 -5.15 -4.92 -1.84 -2.35 -14.42 -12.30 -6.06 -2.03
Bud Neck -5.68 -6.38 -15.86 -13.36 -9.21 -4.47 -6.41 -4.05 -3.01 -2.34 -5.78 -8.68 -15.10 -12.58 -9.54
Bud Site -4.32 -4.84 -5.87 -5.03 -4.82 -1.99 -2.21 -2.63 -2.12 -2.21 -3.10 -3.90 -5.89 -5.14 -5.08
Cell Periphery -6.66 0.81 -5.34 3.34 -6.47 -1.18 3.05 0.20 1.19 -1.50 -2.66 3.03 -1.61 2.02 -5.96
Cytoplasm -1.02 3.35 -0.91 0.31 -7.22 2.62 4.78 2.77 0.21 -3.19 1.45 5.72 0.70 -0.98 -7.47
Cytoplasmic Foci -0.45 1.66 -1.31 -1.10 -2.61 1.53 3.17 2.95 2.36 -1.42 0.76 3.54 -0.97 -1.40 -2.63
Eisosomes -7.21 -9.03 -17.34 -1.87 3.53 -2.22 -8.43 -4.02 -3.12 0.90 -6.04 -12.12 -12.32 -4.35 4.46
Endoplasmic Reticulum -14.09 -4.83 -14.69 2.85 -7.79 -8.92 -1.28 -2.12 0.73 -1.79 -14.85 -3.58 -10.08 2.94 -6.91
Endosome -3.58 1.23 -4.31 -3.68 -4.40 -0.44 3.03 1.26 1.54 -2.93 -1.00 3.12 -3.63 -3.28 -4.43
Golgi -1.55 0.40 -2.43 -0.81 -2.59 0.58 1.16 0.86 0.69 -2.15 -0.39 1.20 -1.58 -1.40 -2.62
Lipid Particles 0.15 1.40 -1.12 -1.53 -2.75 -0.93 3.60 -0.73 0.32 -2.14 -0.69 2.75 -1.71 -1.22 -2.90
Mitochondria -3.31 -3.59 -4.87 -3.85 -4.24 -2.30 -1.05 -2.44 0.96 -2.58 -3.30 -2.21 -4.78 -3.47 -4.41
Mitotic Spindle -2.40 -1.21 -6.33 -5.44 -6.25 -2.04 -0.92 -2.63 -2.46 -2.16 -2.96 -0.97 -6.71 -6.02 -4.20
None -3.62 4.54 3.16 6.86 -5.90 3.02 5.09 3.88 1.09 -1.77 -1.84 6.75 4.57 6.33 -5.48
Nuclear Periphery -1.32 0.98 -6.67 -6.42 -7.05 -2.40 0.62 -2.66 -1.28 -2.97 -2.53 0.73 -6.78 -5.78 -7.12
Nuclear Periphery Foci -2.42 1.76 -2.92 -1.95 -3.19 0.92 1.55 -0.13 -1.00 -1.58 0.06 1.69 -2.19 -2.40 -3.22
Nucleolus -2.63 -2.74 1.83 5.70 3.33 5.39 2.49 5.22 1.05 1.95 2.93 0.16 6.82 4.46 3.71
Nucleus 6.56 2.50 11.44 6.52 8.37 0.00 -0.97 2.76 2.76 3.04 4.09 0.29 10.93 8.69 9.76
Peroxisomes -1.91 -6.13 -2.59 0.96 3.05 -0.67 -0.25 0.28 1.10 0.93 -1.74 -2.19 -1.02 1.06 0.97
Vacuole -2.60 -1.91 -7.40 -6.15 -7.07 -2.07 0.02 -3.02 -1.78 -3.13 -2.67 -0.69 -7.22 -5.80 -7.22
Vacuole Periphery 0.36 0.90 -1.59 -2.51 -3.09 -2.01 1.42 0.72 2.43 -1.50 -0.90 1.29 -2.43 -2.10 -3.14
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Basic leucine zipper (bZIP) transcription factor from ATF/CREB family involved in stress-responsive regulatory network; mediates transcriptional activation of NCE103 in response to low CO2 levels; proposed to be a regulator of oleate responsive genes; involved in utilization of non-optimal carbon sources and chromosome stability; relocalizes to the cytosol in response to hypoxia; CST6 has a paralog, ACA1, that arose from the whole genome duplication
Localization
Cell Percentages nucleus (99%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Cst6

Cst6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cst6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available