Standard name
Human Ortholog
Description GPI-glycan remodelase; conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; functional ortholog of mammalian GPI-glycan remodelase PGAP5; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Bud 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.09 0.11 0 0 0 0 0 0
Cytoplasm 0.77 0.84 1.0 0.81 0.82 0.61 0.65 0.65 0.53 0.64 0.43 0.45 0.9 0.96 0.93 0.66 0.49 0.62 0.47 0.58 0.44 0.61 0.67 0.59
Endoplasmic Reticulum 0 0.09 0 0.07 0.05 0 0 0 0.05 0 0 0 0.07 0 0 0 0.05 0.11 0.19 0.16 0.15 0.2 0.09 0.07
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.21 0 0.17 0.16 0.26 0.44 0.53 0.48 0.62 0.42 0.77 0.69 0 0 0 0.06 0.08 0.09 0.16 0.08 0.23 0.06 0.06 0.06
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.09 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.19 0.29 0.11 0 0.05 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 4 4 5 0 1 2 6 9 9
Bud 0 1 0 0 2 1 1 2 3 0 2 2 0 1 1 1 0 1 2 2 0 3 10 11
Bud Neck 0 0 0 0 0 2 0 0 0 0 1 0 1 0 0 0 2 0 0 1 0 3 9 11
Bud Site 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 0 0 1 0 0 1 2 2 2 8 4 7 17 13 10 0 2 0 2 6 10
Cytoplasm 41 90 18 35 32 68 60 116 61 47 48 29 290 354 354 128 71 56 45 80 21 145 241 204
Endoplasmic Reticulum 1 10 0 3 2 5 4 2 6 1 1 0 22 10 14 8 7 10 17 22 7 48 33 25
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 6 5 1 2 1 0 0 4 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 1 1 0 1 1 1 1
Mitochondria 11 2 3 7 10 49 49 85 71 31 85 45 2 3 1 12 11 8 15 11 11 15 21 21
Nucleus 1 1 0 0 0 1 0 2 0 1 1 1 1 0 2 2 1 1 0 0 0 0 0 0
Nuclear Periphery 0 0 0 1 0 1 0 0 2 1 1 1 0 1 0 0 1 0 1 3 0 0 0 0
Nucleolus 1 1 0 1 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 2 1 3 1 0 2 0 0 1 1 1 2 1 1 0 2 9 10
Vac/Vac Membrane 5 3 0 1 2 1 3 4 4 2 2 2 6 1 7 37 42 10 4 6 0 2 5 17
Unique Cell Count 53 107 18 43 39 112 93 178 115 74 111 65 322 367 382 195 144 91 95 140 49 240 363 344
Labelled Cell Count 60 109 21 48 48 129 119 213 153 86 143 85 333 376 389 218 160 106 95 140 49 240 363 344


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.7 4.4 4.1 3.9 3.9 3.6 3.2 3.4 3.4 6.2 3.1 3.3 4.5 4.4 4.7 6.7 8.1 7.4 4.4 4.4 5.2
Std Deviation (1e-4) 1.0 1.2 2.6 1.6 1.5 1.5 1.6 1.6 1.9 9.1 1.4 1.9 1.3 1.2 1.7 1.4 1.7 1.7 1.8 1.8 1.7
Intensity Change (Log2) – – – -0.08 -0.06 -0.19 -0.36 -0.27 -0.25 0.61 -0.39 -0.3 0.12 0.09 0.19 0.72 0.99 0.85 0.09 0.1 0.33


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9902 1.3109 1.5202 1.0501 1.3056 1.2665 2.2282 2.2578 2.7056 2.0506 2.6207 2.4064 5.22 3.7846 3.2473 4.1901 4.4989 2.5492
Actin 0.049 0.0008 0.0466 0.0006 0.0415 0.0072 0.0028 0.0155 0.0181 0 0.0541 0.0301 0.1897 0 0.0083 0.0004 0.0003 0.0127
Bud 0.0005 0.0019 0.0114 0.0002 0.0001 0.0007 0.0001 0.0032 0.0003 0 0.0004 0.0004 0.0032 0 0 0.0001 0.1188 0.0031
Bud Neck 0.0031 0.0004 0.0007 0.0001 0.0005 0.0033 0.0001 0.0001 0.0003 0 0.0002 0.0004 0.0097 0 0.0001 0.0035 0.001 0.0301
Bud Periphery 0.0007 0.0051 0.0111 0.0007 0.0002 0.002 0.0001 0.0071 0.0005 0 0.0008 0.0007 0.0092 0 0.0001 0.0006 0.0457 0.0142
Bud Site 0.0082 0.0118 0.0035 0.0001 0.0003 0.0016 0.0003 0.009 0.0025 0 0.0002 0.0004 0.0046 0 0.0001 0.0005 0.0128 0.0012
Cell Periphery 0.0013 0.0012 0.0013 0.0004 0.0002 0.0003 0.0002 0.0008 0.0006 0 0.0001 0.0002 0.0014 0.0001 0.0001 0.0073 0.003 0.0005
Cytoplasm 0.1072 0.1869 0.1589 0.1513 0.0885 0.1557 0.1768 0.1152 0.1543 0.0009 0.0956 0.2056 0.0044 0.1067 0.0693 0.3111 0.0375 0.1607
Cytoplasmic Foci 0.0466 0.0121 0.0116 0.0062 0.0033 0.0119 0.0041 0.0052 0.0326 0.0002 0.0016 0.0159 0.0054 0.001 0.0028 0.0042 0.0092 0.0055
Eisosomes 0.0038 0.0002 0.0004 0.0002 0.0003 0.0002 0.0002 0.0004 0.0006 0 0.0004 0.0001 0.0019 0.0002 0.0003 0.0004 0 0.0002
Endoplasmic Reticulum 0.0923 0.0497 0.0836 0.1319 0.1645 0.0402 0.1922 0.0646 0.052 0 0.1786 0.0501 0.0345 0.0064 0.1842 0.0949 0.0057 0.1002
Endosome 0.0154 0.0084 0.0049 0.0078 0.0231 0.0065 0.0199 0.0036 0.0205 0 0.0029 0.0285 0.0728 0.0003 0.0044 0.0049 0.061 0.0015
Golgi 0.0052 0.0007 0.0022 0.0005 0.0065 0.0023 0.0012 0.0075 0.0077 0 0.0113 0.0134 0.0312 0 0.0071 0.0003 0.0029 0.0003
Lipid Particles 0.0352 0.0054 0.0037 0.0027 0.0085 0.0095 0.0011 0.0018 0.0062 0 0.0007 0.0114 0.0215 0.0002 0.0009 0.0055 0.0036 0.0006
Mitochondria 0.0037 0.0012 0.0095 0.0011 0.0014 0.0078 0.0007 0.0015 0.0329 0 0.0179 0.0202 0.0267 0.0001 0.0689 0.0009 0.0026 0.0009
None 0.4936 0.6844 0.6206 0.6756 0.6289 0.7163 0.57 0.7548 0.6474 0.9988 0.6325 0.591 0.5021 0.8835 0.6221 0.5399 0.6084 0.6603
Nuclear Periphery 0.0341 0.0091 0.0048 0.0129 0.0244 0.0162 0.0142 0.0041 0.0082 0 0.0007 0.0061 0.0489 0.0003 0.0109 0.0042 0.002 0.0026
Nucleolus 0.0128 0.001 0.0006 0.0003 0.0002 0.0006 0.0003 0.0003 0.0003 0 0 0.0001 0.0011 0.0001 0.0001 0.0006 0.0014 0.0002
Nucleus 0.0285 0.0068 0.0033 0.0021 0.0014 0.0067 0.007 0.0011 0.0011 0 0.0004 0.0015 0.0042 0.0002 0.0034 0.0041 0.0045 0.002
Peroxisomes 0.0314 0.0023 0.0152 0.0003 0.0005 0.0033 0.0002 0.0008 0.0081 0 0.0007 0.0202 0.0037 0 0.0134 0.0001 0.0003 0.0004
Punctate Nuclear 0.022 0.0057 0.0031 0.001 0.0033 0.0059 0.0062 0.0013 0.0018 0 0.0002 0.0012 0.0038 0.0001 0.0002 0.0007 0.0006 0.0014
Vacuole 0.0042 0.0047 0.0024 0.0032 0.0012 0.0014 0.0017 0.0017 0.0026 0 0.0004 0.0016 0.0095 0.0005 0.0028 0.0152 0.0735 0.0012
Vacuole Periphery 0.0013 0.0004 0.0005 0.0007 0.0011 0.0005 0.0006 0.0004 0.0014 0 0.0002 0.0007 0.0105 0 0.0005 0.0004 0.0049 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 72.5516 47.1685 59.7077 66.2617 66.9027 51.1845 66.2779 62.9577 68.4448 70.0485
Translational Efficiency 1.0089 1.2201 0.9612 0.7998 0.7837 1.2686 0.9448 0.8706 0.7831 0.7788

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1554 1398 64 1387 442 1148 119 99 1996 2546 183 1486

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 655.01 662.62 960.29 800.81 722.50 634.09 957.74 860.59 669.96 649.76 958.63 804.79
Standard Deviation 75.43 82.16 128.85 130.31 83.30 99.79 149.21 123.16 82.17 91.64 142.43 130.69
Intensity Change Log 2 — 0.016665 0.551953 0.289943 — -0.188310 0.406636 0.252328 — -0.087207 0.477562 0.270337

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000196 0.000776 0.000592 0.000983 0.000325 0.000398 0.000549 0.001442 0.000225 0.000606 0.000564 0.001013
Bud Neck 0.021769 0.048587 0.001862 0.014537 0.002663 0.053597 0.002046 0.005182 0.017538 0.050846 0.001982 0.013913
Bud Site 0.005275 0.034696 0.001758 0.051173 0.004584 0.017255 0.004268 0.020230 0.005122 0.026832 0.003390 0.049112
Cell Periphery 0.000269 0.000159 0.000400 0.000295 0.000242 0.000479 0.000562 0.000804 0.000263 0.000303 0.000505 0.000329
Cytoplasm 0.496334* 0.327958* 0.208124* 0.443536* 0.533858* 0.289726* 0.293484* 0.359785* 0.504644* 0.310719* 0.263631* 0.437956*
Cytoplasmic Foci 0.165571 0.305259* 0.036762 0.025165 0.128967 0.217936* 0.031842 0.070933 0.157465 0.265884* 0.033563 0.028215
Eisosomes 0.000232 0.000176 0.000132 0.000061 0.000171 0.000222 0.000133 0.000240 0.000219 0.000197 0.000132 0.000073
Endoplasmic Reticulum 0.011941 0.006493 0.126519* 0.031064 0.032798 0.006631 0.153397* 0.039000 0.016559 0.006556 0.143997* 0.031593
Endosome 0.012197 0.039014 0.010341 0.008854 0.004353 0.045144 0.008389 0.025604 0.010460 0.041778 0.009072 0.009970
Golgi 0.001897 0.011618 0.000209 0.003885 0.000664 0.009553 0.001103 0.003381 0.001624 0.010687 0.000790 0.003851
Lipid Particles 0.010893 0.010186 0.012761 0.004431 0.009535 0.025209 0.007991 0.015096 0.010592 0.016960 0.009659 0.005141
Mitochondria 0.004406 0.019222 0.000353 0.005432 0.000599 0.025528 0.000235 0.001532 0.003563 0.022065 0.000276 0.005172
Mitotic Spindle 0.001068 0.004005 0.000178 0.059659 0.002369 0.009312 0.000127 0.030573 0.001356 0.006398 0.000145 0.057722
None 0.009598 0.003971 0.001689 0.006138 0.006519 0.014885 0.002082 0.004860 0.008916 0.008892 0.001945 0.006053
Nuclear Periphery 0.001701 0.000507 0.023526 0.010706 0.003739 0.003253 0.007146 0.002152 0.002152 0.001745 0.012874 0.010136
Nuclear Periphery Foci 0.001024 0.000711 0.036541 0.009650 0.004009 0.000961 0.034252 0.023727 0.001685 0.000824 0.035053 0.010588
Nucleolus 0.001636 0.002657 0.001090 0.001735 0.001369 0.009730 0.000513 0.000446 0.001577 0.005846 0.000715 0.001649
Nucleus 0.186285* 0.067664 0.406723* 0.188334* 0.238859* 0.156418* 0.313983* 0.137783* 0.197927* 0.107683 0.346417* 0.184966*
Peroxisomes 0.003041 0.036243 0.000791 0.002377 0.001263 0.019125 0.000472 0.002034 0.002647 0.028524 0.000584 0.002355
Vacuole 0.063483 0.077284 0.129118 0.127915 0.022077 0.089666 0.137204 0.250572* 0.054314 0.082867 0.134376 0.136086
Vacuole Periphery 0.001186 0.002814 0.000531 0.004069 0.001037 0.004972 0.000222 0.004624 0.001153 0.003787 0.000330 0.004106

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.26 -3.08 -2.65 0.38 0.16 -0.22 -0.58 -1.35 -1.51 -0.95 -3.26 -2.29 -2.67 -0.61 -0.57
Bud Neck -8.71 11.79 5.36 13.42 -8.97 -14.86 1.32 -1.24 14.20 -2.07 -13.52 11.90 4.08 17.38 -9.52
Bud Site -11.19 4.08 -8.35 0.90 -9.57 -4.17 0.35 -1.59 0.82 -1.84 -11.71 1.65 -8.48 -0.91 -8.92
Cell Periphery 6.08 -2.06 2.95 -1.75 3.01 -2.79 -1.20 -0.80 0.50 0.28 -1.16 -1.60 1.87 2.65 2.06
Cytoplasm 17.53 10.63 11.83 -4.96 -6.17 16.96 9.59 7.66 -0.10 -0.06 25.29 13.38 14.07 -7.03 -5.94
Cytoplasmic Foci -18.50 13.61 33.21 44.53 1.68 -9.46 12.55 8.48 18.72 -2.10 -18.83 23.73 35.30 52.63 2.25
Eisosomes 4.07 3.57 14.93 11.34 3.68 -0.71 0.46 0.05 1.50 -0.73 1.19 3.35 8.01 16.97 4.42
Endoplasmic Reticulum 2.11 -3.11 -0.99 -3.20 3.00 3.67 -2.77 1.57 -1.51 3.39 3.92 -4.57 0.38 -3.59 4.64
Endosome -11.76 1.01 7.39 15.47 2.98 -17.01 -2.05 -1.97 6.64 -1.27 -18.40 1.79 5.70 21.57 2.37
Golgi -9.95 5.01 0.54 10.03 -3.61 -5.52 0.10 -0.47 4.50 -0.47 -9.90 2.32 0.13 9.58 -1.94
Lipid Particles 0.52 -0.44 7.76 6.50 3.90 -6.02 1.21 0.70 6.54 -0.33 -5.25 1.49 7.59 12.36 4.13
Mitochondria -7.24 4.72 1.41 8.33 -3.76 -10.66 2.91 -0.15 10.51 -1.13 -11.46 4.91 0.91 12.13 -3.93
Mitotic Spindle -4.10 1.89 -9.42 -8.63 -9.72 -2.19 1.37 -1.29 -0.67 -1.58 -4.26 2.31 -9.37 -7.84 -9.85
None 3.67 6.02 3.04 -1.11 -4.72 -3.57 3.26 2.14 5.47 -1.29 -0.04 6.46 3.17 3.29 -4.51
Nuclear Periphery 2.96 -2.89 -4.36 -5.45 1.87 0.37 -1.31 1.56 1.35 3.02 0.78 -3.60 -3.99 -4.32 1.27
Nuclear Periphery Foci 0.91 -3.21 -4.88 -5.26 2.65 2.92 -2.65 -1.74 -2.38 1.19 2.55 -4.23 -4.62 -5.68 3.37
Nucleolus -3.17 1.97 0.56 2.99 -0.87 -6.22 2.02 2.16 7.99 0.68 -7.29 4.36 0.79 7.17 -1.96
Nucleus 21.61 -5.86 -6.47 -23.85 4.56 7.22 -3.84 4.88 1.04 6.64 17.20 -7.87 -4.29 -17.79 6.29
Peroxisomes -15.30 6.54 4.24 16.17 -1.11 -10.77 2.02 0.73 11.60 -1.67 -18.49 7.57 3.89 19.60 -2.12
Vacuole -3.77 -4.06 -22.30 -19.70 -3.10 -14.21 -8.37 -12.51 -10.39 -6.38 -8.74 -8.04 -25.81 -21.40 -4.13
Vacuole Periphery -6.97 3.35 -1.16 1.77 -2.44 -5.35 1.50 -0.51 2.33 -1.20 -9.11 5.12 -1.25 3.63 -3.07
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description GPI-glycan remodelase; conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; functional ortholog of mammalian GPI-glycan remodelase PGAP5; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
Localization
Cell Percentages cytoplasm (40%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ted1

Ted1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ted1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available