Standard name
Human Ortholog
Description Cytochrome b reductase; not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.06 0.1 0.07 0.05 0 0.06 0.06 0 0.06 0.09 0.05 0 0 0.12 0.11 0.18 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.06 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.06 0.14 0.11 0.14 0 0.06 0.08 0.07 0.06 0.09 0.13 0.21 0.23 0.31 0.34 0.43 0 0 0 0 0 0
Cytoplasm 0.14 0.13 0.09 0.18 0.13 0.19 0.15 0.23 0.27 0.25 0.23 0.2 0.13 0.13 0.24 0.41 0.44 0.26 0 0 0 0 0 0
Endoplasmic Reticulum 0.75 0.85 0.87 0.68 0.65 0.56 0.45 0.42 0.36 0.44 0.4 0.39 0.73 0.78 0.52 0 0 0 0.92 0.87 0.86 0.83 0.85 0.81
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0.08 0.06 0 0 0 0 0 0
Mitochondria 0.1 0 0 0.08 0.05 0.19 0.24 0.19 0.32 0.24 0.36 0.24 0 0 0 0 0 0.08 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.06 0 0 0 0.22 0.19 0.21 0.23 0.14 0.15 0.05 0.17 0.08 0.09 0.2 0.19 0.1 0.05 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 7 10 16 15 13 11 15 15 8 11 22 10 3 5 15 13 19 2 3 3 1 2 4
Bud 3 1 0 1 0 2 15 6 8 5 9 6 3 0 0 1 0 4 0 0 1 1 1 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0
Bud Site 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 6 10 24 22 35 10 17 22 18 12 22 28 38 53 39 40 46 1 1 3 3 4 5
Cytoplasm 22 27 15 30 27 49 39 61 71 63 44 49 27 24 56 51 51 28 0 7 3 4 4 3
Endoplasmic Reticulum 117 173 139 115 135 141 121 114 94 110 77 98 153 139 123 1 3 3 166 192 171 120 173 156
Endosome 3 0 0 1 0 0 2 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 1 1
Golgi 0 0 1 1 1 1 0 0 0 0 0 1 0 0 0 12 9 7 0 1 1 1 1 1
Mitochondria 15 2 0 13 11 48 65 51 84 61 70 61 5 0 1 4 5 9 2 3 6 5 3 6
Nucleus 0 1 3 1 1 2 5 5 3 4 3 2 3 4 4 0 2 0 0 0 0 0 0 0
Nuclear Periphery 3 4 7 0 2 4 11 2 3 5 5 4 3 0 1 0 0 0 1 2 3 0 0 1
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Vac/Vac Membrane 10 3 2 6 45 47 55 61 37 37 10 42 17 17 47 23 12 5 2 6 2 4 7 10
Unique Cell Count 156 203 160 168 209 254 268 271 262 252 193 250 211 179 235 124 116 108 180 222 200 145 204 194
Labelled Cell Count 183 224 187 208 260 342 334 333 338 311 241 307 249 225 291 147 137 123 180 222 200 145 204 194


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.9 12.8 9.3 9.3 9.4 8.3 7.6 8.1 7.1 7.2 6.9 7.5 10.6 10.8 10.6 13.6 15.0 14.5 11.4 11.6 11.8
Std Deviation (1e-4) 1.4 1.9 1.2 1.3 1.3 1.4 1.1 1.4 1.2 1.3 1.2 1.2 1.5 1.5 1.4 2.5 3.3 2.7 1.7 1.8 1.7
Intensity Change (Log2) – – – 0.0 0.01 -0.16 -0.29 -0.19 -0.39 -0.36 -0.43 -0.32 0.2 0.22 0.19 0.55 0.69 0.64 0.29 0.32 0.35


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.1 0.4 -0.5 -1.0 -0.3 -0.2 -1.5 -0.2 0.9 -0.6 -2.2 -2.1 1.7 1.5 2.9
Bud 0 0 0 3.0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 2.4 1.4 2.4 -1.2 0 0.8 0.4 0 0.9 2.2 3.9 4.3 5.6 6.0 7.2
Cytoplasm 2.2 1.1 2.7 1.6 3.5 4.4 3.9 3.4 2.8 1.0 1.2 3.7 6.3 6.6 3.6
Endoplasmic Reticulum -4.0 -4.9 -6.6 -8.6 -9.1 -10.2 -8.7 -9.0 -9.5 -3.3 -2.2 -7.1 -14.4 -13.8 -13.5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 3.6 0 0
Mitochondria 3.6 0 5.8 6.8 5.8 8.0 6.7 8.5 6.8 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 -0.1 0 0 0 -0.9 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 5.8 5.3 5.7 6.0 4.4 4.5 2.0 5.0 2.9 3.3 5.5 5.1 3.4 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.9882 8.4769 7.5324 7.3251 6.2597 7.5881 8.5175 9.5195 8.8169 8.1795 7.7306 8.8093 10.5819 9.7686 9.7147 10.0752 9.4133 9.5218
Actin 0.0052 0.001 0.0175 0.0055 0.0019 0.0087 0.0152 0.0004 0.006 0.0001 0.0001 0.0002 0.0009 0.0007 0.0011 0.0074 0.0005 0.0005
Bud 0.0003 0.0001 0.0002 0.0001 0.0005 0.0001 0.0001 0 0.0001 0 0 0 0.0001 0 0 0.0007 0 0.0004
Bud Neck 0.0102 0.0007 0.0005 0.0004 0.0023 0.002 0.0011 0.0006 0.0018 0.0001 0.0002 0.0001 0.0001 0.0003 0.0003 0.0002 0.0028 0.0013
Bud Periphery 0.0005 0.0002 0.0005 0.0003 0.0023 0.0002 0.0005 0.0001 0.0002 0 0 0.0001 0.0002 0.0001 0.0001 0.0008 0.0001 0.0005
Bud Site 0.0045 0.0032 0.0008 0.0002 0.0004 0.0002 0.0006 0.0003 0.0005 0 0 0 0.0002 0.0007 0.0002 0.0004 0 0.0001
Cell Periphery 0.0024 0.0063 0.0025 0.0011 0.0036 0.001 0.0011 0.0064 0.0028 0.0005 0.0019 0.001 0.0018 0.0061 0.0034 0.0009 0.002 0.0019
Cytoplasm 0.0415 0.0963 0.0499 0.0152 0.0101 0.0408 0.0064 0.0171 0.0067 0.0013 0.0019 0.0038 0.0114 0.0311 0.0162 0.0112 0.0969 0.0202
Cytoplasmic Foci 0.0147 0.0023 0.0046 0.0013 0.0022 0.0013 0.0095 0.0005 0.004 0.0001 0.0001 0.0002 0.0019 0.0008 0.0004 0.0018 0.001 0.0005
Eisosomes 0.0002 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001 0.0006 0.0001 0 0 0.0001 0.0001 0 0.0003 0 0
Endoplasmic Reticulum 0.7633 0.8494 0.8468 0.8937 0.8659 0.9228 0.8856 0.9469 0.9463 0.9504 0.9491 0.9806 0.9545 0.9381 0.9612 0.9567 0.8849 0.9589
Endosome 0.0412 0.0078 0.02 0.0137 0.0477 0.0051 0.0101 0.0023 0.0059 0.0003 0.0037 0.0032 0.0023 0.0022 0.0029 0.0008 0.0024 0.0019
Golgi 0.008 0.0018 0.0054 0.0022 0.0095 0.0021 0.0034 0.0005 0.0033 0 0.0009 0.0006 0.0006 0.001 0.0007 0.0006 0.0003 0.0003
Lipid Particles 0.0229 0.0057 0.0056 0.0025 0.0039 0.0015 0.0136 0.0081 0.004 0.0002 0.0025 0.0017 0.0035 0.0086 0.0029 0.0021 0.0006 0.0015
Mitochondria 0.0021 0.0005 0.0061 0.0017 0.0099 0.0006 0.0029 0.0001 0.0086 0 0.0001 0.0007 0.0001 0.0002 0.0001 0.0005 0.0001 0.0003
None 0.004 0.0005 0.0053 0.0011 0.0003 0.0006 0.0027 0.0001 0.0002 0.0274 0.0001 0.0001 0.0013 0.0004 0.0001 0.0026 0.0005 0.0002
Nuclear Periphery 0.0333 0.0126 0.0184 0.047 0.0143 0.0079 0.0166 0.0119 0.004 0.0032 0.0366 0.0053 0.017 0.0054 0.0055 0.0079 0.0054 0.0054
Nucleolus 0.0013 0.0001 0.0002 0.0002 0.0001 0 0.0005 0 0.0002 0.0027 0 0 0.0001 0 0 0.0003 0 0.0002
Nucleus 0.0122 0.004 0.0066 0.0053 0.0021 0.0015 0.0063 0.001 0.0012 0.0075 0.0002 0.0003 0.0009 0.0005 0.0014 0.0013 0.0004 0.0028
Peroxisomes 0.0021 0 0.001 0.0004 0.0001 0.0004 0.0063 0 0.0013 0 0 0 0 0 0 0.0001 0 0
Punctate Nuclear 0.0159 0.0007 0.0014 0.003 0.0002 0.0005 0.0102 0.0002 0.0003 0.0047 0.0002 0.0001 0.0002 0.0002 0.0002 0.0014 0.0001 0.0008
Vacuole 0.0118 0.0062 0.0048 0.0034 0.0192 0.0024 0.0057 0.0033 0.0015 0.0012 0.0017 0.0013 0.0025 0.0034 0.0032 0.0013 0.0018 0.0022
Vacuole Periphery 0.0024 0.0005 0.0015 0.0016 0.0035 0.0003 0.0016 0.0002 0.0004 0.0001 0.0007 0.0004 0.0004 0.0002 0.0002 0.0007 0.0002 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 247.1368 261.88 289.3492 230.7263 212.5003 261.8329 243.4987 231.8547 261.5729 223.4663
Translational Efficiency 1.0485 0.8719 0.8476 1.0194 1.0849 0.8268 0.8386 0.845 0.7921 0.8144

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
31 460 1720 1362 1860 1169 1463 1351 1891 1629 3183 2713

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 965.05 1107.67 1259.52 1233.81 985.84 1061.42 1226.64 1217.11 985.50 1074.48 1244.41 1225.49
Standard Deviation 133.67 195.47 225.11 213.17 141.38 153.27 205.49 203.09 141.28 167.58 216.94 208.38
Intensity Change Log 2 — 0.198853 0.384198 0.354445 — 0.106570 0.315286 0.304034 — 0.152957 0.349787 0.329191

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000855 0.000981 0.002073 0.003775 0.000658 0.000779 0.003364 0.005193 0.000662 0.000836 0.002667 0.004481
Bud Neck 0.004118 0.000500 0.001631 0.004798 0.000086 0.000216 0.004222 0.004478 0.000152 0.000296 0.002822 0.004639
Bud Site 0.017010 0.009011 0.013819 0.030668 0.001534 0.003877 0.023678 0.023911 0.001788 0.005327 0.018351 0.027303
Cell Periphery 0.006895 0.002393 0.004023 0.004646 0.001513 0.002630 0.002005 0.009779 0.001601 0.002563 0.003095 0.007202
Cytoplasm 0.014424 0.017159 0.026113 0.047973 0.011281 0.014347 0.090058 0.050833 0.011332 0.015141 0.055504 0.049397
Cytoplasmic Foci 0.012130 0.011321 0.002921 0.009436 0.004028 0.006554 0.017168 0.006560 0.004160 0.007900 0.009469 0.008004
Eisosomes 0.000054 0.000054 0.000165 0.000179 0.000033 0.000141 0.000181 0.000524 0.000033 0.000116 0.000173 0.000351
Endoplasmic Reticulum 0.912695* 0.907788* 0.908716* 0.772803* 0.967637* 0.945756* 0.688300* 0.801889* 0.966737* 0.935035* 0.807406* 0.787287*
Endosome 0.006008 0.012460 0.007155 0.015958 0.002099 0.005573 0.013396 0.011961 0.002163 0.007518 0.010024 0.013967
Golgi 0.003924 0.006324 0.002035 0.005557 0.001535 0.003495 0.003051 0.004214 0.001574 0.004294 0.002502 0.004888
Lipid Particles 0.002874 0.004131 0.006533 0.017900 0.001313 0.003275 0.018266 0.021680 0.001338 0.003517 0.011926 0.019782
Mitochondria 0.004610 0.005040 0.000631 0.001599 0.001727 0.002140 0.000931 0.001309 0.001775 0.002959 0.000769 0.001455
Mitotic Spindle 0.000108 0.000473 0.000538 0.006080 0.000127 0.000406 0.002496 0.002570 0.000127 0.000425 0.001438 0.004332
None 0.000105 0.001078 0.000958 0.000966 0.001270 0.001026 0.001764 0.000873 0.001251 0.001041 0.001329 0.000919
Nuclear Periphery 0.000240 0.000791 0.001266 0.002760 0.000270 0.000354 0.021028 0.000873 0.000269 0.000477 0.010349 0.001820
Nuclear Periphery Foci 0.005941 0.007795 0.010791 0.028959 0.001559 0.002143 0.062476 0.013715 0.001631 0.003739 0.034547 0.021368
Nucleolus 0.000013 0.000045 0.000046 0.000113 0.000027 0.000184 0.000126 0.000064 0.000027 0.000144 0.000083 0.000089
Nucleus 0.000401 0.000553 0.001901 0.006425 0.000283 0.000594 0.015583 0.006515 0.000285 0.000582 0.008190 0.006470
Peroxisomes 0.001159 0.000807 0.000342 0.000503 0.000737 0.001516 0.000808 0.000524 0.000744 0.001315 0.000556 0.000514
Vacuole 0.003104 0.008542 0.007535 0.036395 0.001261 0.003164 0.029729 0.030526 0.001291 0.004683 0.017736 0.033473
Vacuole Periphery 0.003334 0.002755 0.000809 0.002507 0.001022 0.001832 0.001369 0.002009 0.001059 0.002092 0.001066 0.002259

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.23 -1.74 -3.94 -4.17 -2.41 -0.28 -4.99 -5.05 -5.12 -2.18 -0.43 -4.17 -6.31 -6.73 -3.28
Bud Neck 0.90 0.60 -0.52 -8.39 -6.38 -2.52 -7.97 -9.40 -9.14 -1.05 -1.73 -9.79 -12.67 -12.44 -5.41
Bud Site 0.59 0.20 -1.27 -6.25 -5.55 -2.20 -8.52 -10.23 -8.70 -0.74 -3.22 -10.60 -14.18 -11.32 -4.64
Cell Periphery 0.84 0.53 0.44 -3.07 -0.65 -2.08 -1.21 -7.86 -6.53 -7.41 -2.07 -3.29 -8.58 -6.95 -6.13
Cytoplasm -0.68 -2.21 -6.33 -7.71 -6.64 -1.79 -17.54 -12.99 -11.00 6.58 -2.52 -17.20 -17.22 -13.92 0.76
Cytoplasmic Foci 0.12 1.61 0.35 0.42 -6.13 -1.69 -7.87 -2.70 -0.37 5.99 -2.63 -5.32 -4.37 -0.52 1.34
Eisosomes 0.01 -1.99 -3.33 -4.14 -0.27 -2.42 -6.41 -5.99 -4.17 -4.02 -2.55 -4.80 -7.30 -4.44 -3.45
Endoplasmic Reticulum 0.21 0.23 5.03 11.80 15.03 4.20 30.43 20.83 16.71 -7.94 6.40 27.68 29.75 22.06 4.80
Endosome -2.99 -0.89 -5.87 -2.02 -7.70 -3.97 -15.92 -10.26 -5.08 1.20 -6.79 -17.01 -16.71 -6.44 -4.84
Golgi -0.99 1.06 -0.77 0.48 -3.37 -2.41 -2.44 -2.99 -0.60 -1.26 -3.32 -1.85 -4.43 -0.49 -3.42
Lipid Particles -1.01 -2.80 -8.67 -8.40 -6.76 -3.06 -11.67 -10.67 -9.32 -1.46 -4.08 -12.39 -15.18 -12.76 -5.55
Mitochondria -0.10 1.10 0.83 1.39 -1.98 -0.62 2.02 0.94 1.34 -1.71 -1.36 2.61 0.67 1.78 -2.57
Mitotic Spindle -1.15 -2.32 -5.24 -4.87 -4.86 -1.36 -3.84 -3.04 -2.65 -0.02 -1.71 -4.34 -6.04 -5.57 -4.02
None -2.55 -3.65 -2.41 0.18 -0.04 0.60 -0.84 1.33 0.38 1.48 0.62 -0.26 1.09 0.33 1.15
Nuclear Periphery -2.74 -6.28 -4.85 -3.72 -2.97 -1.05 -10.41 -4.96 -4.01 10.07 -2.46 -10.77 -5.74 -4.95 8.50
Nuclear Periphery Foci -0.53 -1.51 -5.87 -7.11 -6.81 -1.53 -18.95 -9.39 -8.79 13.93 -3.52 -19.83 -13.82 -11.70 5.53
Nucleolus -1.75 -2.08 -2.35 -1.70 -1.65 -1.14 -3.68 -2.34 0.81 2.13 -1.18 -3.08 -2.58 0.39 -0.55
Nucleus -0.83 -3.92 -7.40 -7.28 -5.74 -1.76 -12.02 -8.64 -8.18 4.80 -2.20 -12.61 -11.39 -10.82 0.08
Peroxisomes 0.45 1.15 0.89 0.80 -1.62 -1.94 -0.52 1.50 2.43 1.73 -1.84 1.50 1.91 2.59 0.35
Vacuole -2.31 -2.63 -12.04 -10.54 -11.67 -3.27 -15.19 -12.57 -11.76 -2.08 -5.20 -16.48 -18.88 -16.74 -9.94
Vacuole Periphery 0.28 1.29 0.44 0.33 -3.51 -1.23 -0.62 -1.85 -0.19 -0.96 -1.89 -0.06 -2.86 -0.23 -2.95
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Cytochrome b reductase; not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia
Localization
Cell Percentages ER (100%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Cbr1

Cbr1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cbr1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available