Standard name
Human Ortholog
Description Pho85p cyclin of the Pho80p subfamily; forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated; PCL7 has a paralog, PCL6, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.05 0 0 0 0 0 0 0
Cytoplasm 0.99 0.97 1.0 0.96 0.93 0.92 0.93 0.87 0.8 0.81 0.76 0.81 0.95 0.99 1.0 0.95 0.95 0.94 0.98 0.96 0.93 0.87 0.86 0.82
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.08 0.08 0.18 0.16 0.38 0.24 0.34 0.27 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 1 0 1 2
Bud 0 1 0 0 4 1 4 2 1 7 10 5 0 0 0 0 0 0 0 0 3 4 5 12
Bud Neck 0 0 1 0 0 0 1 2 0 4 1 2 0 0 0 0 0 0 0 0 1 0 0 2
Bud Site 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 10 3 0 3 0 2 2 0 3 2 2 1 1 18 14 10 0 0 1 0 0 1
Cytoplasm 128 200 399 198 230 230 154 228 117 193 229 255 124 291 285 361 247 261 128 208 367 214 219 253
Endoplasmic Reticulum 1 1 0 0 2 0 1 0 0 0 2 0 0 0 0 14 12 10 0 0 0 4 4 2
Endosome 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 6 6 5 1 0 3 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 1 3
Mitochondria 1 6 0 7 19 21 30 41 56 57 103 86 3 2 0 14 4 3 0 4 2 2 4 7
Nucleus 1 1 0 3 5 1 3 2 1 2 1 1 0 0 0 0 2 1 0 0 0 3 2 1
Nuclear Periphery 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 2 0 0 1 1 0 1 2 1 4 2 0 0 0 0 0 0 0 7 3 9
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 2
SpindlePole 0 0 0 0 0 0 0 3 0 1 0 3 0 0 0 1 1 0 0 0 0 1 1 4
Vac/Vac Membrane 0 0 0 3 4 12 1 5 1 2 4 2 0 0 0 6 3 9 0 0 1 3 4 0
Unique Cell Count 129 207 400 206 246 250 166 261 146 237 303 316 130 293 285 379 259 278 132 217 394 246 256 311
Labelled Cell Count 131 211 411 216 264 268 195 289 180 267 357 359 134 296 286 422 290 303 132 217 394 246 256 311


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 4.4 6.2 5.7 5.0 4.9 3.7 4.9 4.1 4.2 4.0 4.1 8.0 6.7 5.4 6.6 8.4 8.2 9.6 9.0 11.4
Std Deviation (1e-4) 0.7 0.6 1.4 1.4 1.6 1.1 1.2 1.4 1.2 1.1 0.8 0.8 10.7 5.1 1.3 1.5 2.0 1.7 14.5 14.5 22.4
Intensity Change (Log2) – – – -0.12 -0.31 -0.36 -0.73 -0.34 -0.61 -0.58 -0.65 -0.59 0.37 0.1 -0.2 0.09 0.43 0.4 0.62 0.54 0.88

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.1428 4.2863 4.6478 4.1916 3.9015 4.6578 6.109 4.202 4.3361 3.3625 4.6543 4.4426 1.8866 1.456 1.7193 2.1786 1.3289 1.7098
Actin 0.055 0.0013 0.0408 0.001 0.0665 0.0125 0.1549 0.0022 0.0218 0.0199 0.0111 0.0079 0.0692 0.0002 0.0131 0.0003 0.0182 0.0071
Bud 0.0017 0.0041 0.0065 0.0008 0.0004 0.001 0.0021 0.0023 0.002 0.0017 0.0001 0.0003 0.0026 0.0002 0.0018 0.0001 0.0006 0.0005
Bud Neck 0.0013 0.0003 0.0056 0.0003 0.0005 0.0007 0.0494 0.0002 0.0013 0.0006 0.0004 0.0003 0.0034 0.0001 0.003 0.0001 0.0005 0.0037
Bud Periphery 0.0036 0.0041 0.0031 0.0029 0.0004 0.001 0.0018 0.0026 0.003 0.0017 0.0002 0.0004 0.0034 0.0001 0.0024 0.0001 0.0009 0.0008
Bud Site 0.0061 0.0028 0.0145 0.0003 0.0007 0.0004 0.0124 0.0353 0.0157 0.001 0.0004 0.0003 0.0049 0.0106 0.0061 0 0.0006 0.0003
Cell Periphery 0.0005 0.0002 0.0006 0.0002 0.0001 0.0001 0.0007 0.0005 0.0008 0.0001 0.0001 0.0001 0.0003 0.0001 0.0002 0.0001 0.0001 0.0001
Cytoplasm 0.3399 0.4457 0.4156 0.5556 0.4564 0.4909 0.3063 0.5203 0.4393 0.5598 0.692 0.4778 0.2325 0.4397 0.3411 0.4074 0.3816 0.4682
Cytoplasmic Foci 0.0165 0.0071 0.022 0.0078 0.0146 0.0175 0.0397 0.0107 0.011 0.0703 0.0066 0.0061 0.0187 0.0021 0.0065 0.0028 0.0139 0.0052
Eisosomes 0.0007 0 0.0006 0.0001 0.0004 0.0001 0.0009 0.0001 0.0003 0 0.0002 0.0001 0.0004 0 0.0002 0.0001 0.0002 0.0001
Endoplasmic Reticulum 0.0049 0.0011 0.0027 0.0027 0.0028 0.0017 0.0113 0.0033 0.0028 0.0035 0.0053 0.0017 0.0045 0.0013 0.0014 0.0019 0.0016 0.002
Endosome 0.0133 0.0021 0.0093 0.0177 0.0113 0.0027 0.0447 0.0023 0.0044 0.0094 0.019 0.0042 0.0154 0.0003 0.0087 0.001 0.0025 0.0031
Golgi 0.0051 0.0021 0.005 0.0244 0.0091 0.0017 0.0155 0.0004 0.0063 0.0033 0.0053 0.0062 0.0048 0 0.0012 0.0001 0.0016 0.0006
Lipid Particles 0.0102 0.0001 0.0095 0.0015 0.0069 0.0023 0.0242 0.0006 0.0041 0.0016 0.0071 0.0011 0.0071 0 0.0006 0.0002 0.0053 0.001
Mitochondria 0.0048 0.0052 0.0116 0.003 0.0075 0.0007 0.0061 0.0005 0.0121 0.0016 0.0021 0.0115 0.0025 0.0001 0.001 0.0002 0.0006 0.0008
None 0.503 0.5137 0.418 0.3742 0.386 0.4484 0.1787 0.41 0.46 0.2787 0.2204 0.4767 0.5519 0.5404 0.6027 0.584 0.5437 0.4924
Nuclear Periphery 0.0142 0.0014 0.0016 0.0013 0.0024 0.0009 0.0224 0.0027 0.001 0.006 0.0147 0.0003 0.0186 0.0003 0.001 0.0005 0.0005 0.004
Nucleolus 0.0005 0.0001 0.0006 0.0002 0.0004 0.0007 0.0173 0.0002 0.0002 0.0004 0.0006 0 0.0032 0.0001 0.0006 0 0.0001 0.0004
Nucleus 0.0036 0.0056 0.0099 0.0017 0.0024 0.0015 0.04 0.0015 0.0013 0.0029 0.004 0.0006 0.0099 0.0037 0.002 0.0005 0.0006 0.0059
Peroxisomes 0.0095 0.0008 0.0162 0.0005 0.0139 0.0101 0.0384 0.0007 0.0099 0.0242 0.0023 0.0036 0.0261 0 0.0029 0.0001 0.0241 0.0006
Punctate Nuclear 0.003 0.0018 0.0046 0.0006 0.0163 0.0045 0.0225 0.0023 0.0015 0.0104 0.006 0.0005 0.0173 0.0002 0.001 0.0002 0.0023 0.0026
Vacuole 0.0015 0.0004 0.0014 0.0025 0.0008 0.0004 0.0086 0.001 0.0009 0.0022 0.0013 0.0003 0.0022 0.0003 0.0019 0.0005 0.0004 0.0004
Vacuole Periphery 0.0012 0.0001 0.0003 0.0007 0.0003 0.0002 0.0021 0.0002 0.0002 0.0007 0.0008 0.0001 0.001 0 0.0004 0.0001 0.0001 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.5032 13.7955 8.5307 8.2609 10.838 8.9972 11.6238 12.5525 8.3951 13.3324
Translational Efficiency 0.8842 0.822 0.8283 0.8387 0.8461 1.3888 1.4834 0.9463 1.532 1.209

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
729 1106 2278 1760 1916 1635 151 1612 2645 2741 2429 3372

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 694.59 785.15 967.91 1008.62 719.33 852.09 1092.27 994.40 712.51 825.08 975.64 1001.82
Standard Deviation 108.40 108.75 121.37 132.82 84.04 92.31 121.63 136.31 92.07 104.56 125.05 134.69
Intensity Change Log 2 — 0.176807 0.478711 0.538149 — 0.244352 0.602604 0.467173 — 0.211565 0.543070 0.502476

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000103 0.000479 0.000535 0.002812 0.000362 0.000225 0.000429 0.000412 0.000290 0.000328 0.000528 0.001665
Bud Neck 0.012599 0.021732 0.002038 0.004204 0.009688 0.014840 0.001647 0.002904 0.010490 0.017621 0.002013 0.003583
Bud Site 0.003988 0.025955 0.012740 0.048168 0.005384 0.010719 0.011535 0.029974 0.004999 0.016867 0.012665 0.039470
Cell Periphery 0.000179 0.000096 0.000060 0.000100 0.000146 0.000096 0.000216 0.000076 0.000155 0.000096 0.000070 0.000088
Cytoplasm 0.487132 0.519729 0.746981 0.662118 0.615037 0.596060 0.468529 0.604918 0.579785 0.565260 0.729671 0.634773
Cytoplasmic Foci 0.240970 0.233034 0.017934 0.030492 0.179580 0.174143 0.060493 0.034574 0.196500 0.197906 0.020579 0.032444
Eisosomes 0.000187 0.000084 0.000016 0.000020 0.000136 0.000091 0.000081 0.000026 0.000150 0.000088 0.000020 0.000023
Endoplasmic Reticulum 0.001655 0.000660 0.000596 0.000646 0.001489 0.000367 0.002874 0.000726 0.001535 0.000485 0.000737 0.000684
Endosome 0.026843 0.025418 0.001394 0.005616 0.009305 0.013983 0.010894 0.012150 0.014139 0.018597 0.001984 0.008740
Golgi 0.002697 0.006295 0.000113 0.004601 0.002189 0.003712 0.000225 0.004170 0.002329 0.004754 0.000120 0.004395
Lipid Particles 0.012496 0.004086 0.000498 0.000521 0.005239 0.003090 0.002577 0.000824 0.007239 0.003492 0.000628 0.000666
Mitochondria 0.007039 0.002836 0.000387 0.003250 0.002687 0.004472 0.000063 0.002828 0.003887 0.003812 0.000367 0.003048
Mitotic Spindle 0.000609 0.001307 0.005403 0.051971 0.000986 0.008604 0.000737 0.037885 0.000882 0.005659 0.005113 0.045237
None 0.006765 0.003202 0.003494 0.004408 0.002345 0.001398 0.001645 0.002196 0.003563 0.002126 0.003379 0.003351
Nuclear Periphery 0.000868 0.000211 0.000508 0.000405 0.000202 0.000214 0.000713 0.000438 0.000386 0.000212 0.000521 0.000421
Nuclear Periphery Foci 0.000702 0.000549 0.001211 0.001946 0.000370 0.000308 0.012900 0.001141 0.000461 0.000405 0.001937 0.001561
Nucleolus 0.001505 0.000901 0.000137 0.000255 0.000473 0.000851 0.000163 0.000251 0.000757 0.000871 0.000139 0.000253
Nucleus 0.100764 0.056937 0.119698 0.040580 0.096466 0.070575 0.069129 0.034027 0.097650 0.065072 0.116554 0.037447
Peroxisomes 0.002981 0.009108 0.000728 0.003049 0.001891 0.006218 0.000373 0.001100 0.002192 0.007384 0.000706 0.002117
Vacuole 0.086923 0.085478 0.084830 0.128057 0.065160 0.088007 0.354526 0.225188 0.071158 0.086987 0.101596 0.174491
Vacuole Periphery 0.002996 0.001903 0.000701 0.006781 0.000864 0.002027 0.000249 0.004191 0.001451 0.001977 0.000673 0.005543

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.41 -1.16 -2.90 -1.66 -1.72 0.87 -0.15 0.75 -0.25 2.18 -0.30 -0.32 -1.80 -1.88 -1.08
Bud Neck -3.95 8.21 7.67 10.11 -1.59 -4.03 9.84 9.36 12.66 -1.88 -6.00 12.27 11.72 15.64 -1.56
Bud Site -8.85 -4.11 -7.86 1.91 -4.73 -4.54 -3.97 -5.25 -2.31 -2.56 -9.51 -3.69 -9.00 -0.56 -4.94
Cell Periphery 8.56 13.39 12.16 4.98 -1.31 2.17 -0.73 4.38 5.86 8.57 3.55 5.47 6.00 7.03 2.47
Cytoplasm -2.56 -17.26 -9.06 -6.56 9.35 2.50 9.65 5.62 2.99 -7.19 2.26 -10.36 0.28 -1.95 10.46
Cytoplasmic Foci 1.04 31.84 30.83 31.90 -4.49 0.93 24.91 38.07 31.85 3.89 -0.13 50.37 48.78 44.78 -4.54
Eisosomes 10.40 18.85 18.70 13.55 -1.10 3.89 5.45 11.02 12.50 9.40 7.17 16.11 16.33 17.63 1.41
Endoplasmic Reticulum 2.81 2.34 3.36 1.90 5.79 3.34 -2.01 3.08 -1.17 5.57 3.99 2.25 4.07 0.32 8.19
Endosome 0.61 11.75 11.27 11.74 -2.32 -4.31 2.00 4.38 7.21 1.98 -3.57 16.98 12.71 14.19 -4.76
Golgi -3.49 4.71 1.92 5.07 -2.03 -2.10 8.29 1.48 2.82 -4.13 -4.15 9.55 2.34 5.39 -3.88
Lipid Particles 6.01 9.54 9.46 4.99 -2.30 2.84 5.14 8.37 4.52 6.64 5.62 12.27 12.38 6.64 1.24
Mitochondria 1.76 2.82 2.52 3.12 -1.48 -1.63 5.42 2.53 3.27 -2.64 0.15 4.79 3.59 4.22 -2.41
Mitotic Spindle -1.31 -5.09 -8.09 -7.89 -5.51 -4.58 -1.02 -7.12 -3.58 -6.60 -4.65 -4.98 -10.68 -7.36 -6.95
None 1.80 1.86 1.88 0.10 0.23 1.85 2.23 1.08 -1.53 -2.09 2.10 0.81 1.62 -0.83 1.61
Nuclear Periphery 2.99 0.37 1.06 -7.60 2.92 -0.45 -8.70 -8.09 -7.29 5.08 2.64 -6.04 -2.72 -10.61 5.78
Nuclear Periphery Foci 1.20 -4.32 -4.41 -5.80 -0.43 0.59 -9.08 -6.45 -6.63 8.60 0.68 -10.43 -8.15 -8.63 4.96
Nucleolus 2.39 4.90 4.70 7.89 -2.10 -2.11 3.66 2.86 3.97 -3.82 -0.59 5.98 5.43 6.30 -3.21
Nucleus 7.62 -7.99 6.13 -2.90 20.42 7.42 2.85 15.99 6.97 2.38 11.08 -11.98 14.69 2.56 24.54
Peroxisomes -6.43 6.37 5.00 8.88 -1.20 -5.49 6.02 4.94 7.68 -2.35 -8.51 5.65 5.72 11.36 -0.90
Vacuole -0.43 -8.79 -23.61 -23.77 -16.93 -6.91 -16.75 -33.52 -28.81 5.88 -6.33 -18.03 -42.17 -37.13 -20.46
Vacuole Periphery 1.53 3.63 1.22 0.12 -1.84 -1.95 9.61 -1.69 0.56 -3.35 -1.22 3.80 -0.52 0.45 -2.77
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Pho85p cyclin of the Pho80p subfamily; forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated; PCL7 has a paralog, PCL6, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (75%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Pcl7

Pcl7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pcl7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available