Standard name
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0
Bud 0 0 0.05 0 0 0 0.06 0 0.05 0 0.06 0 0 0 0 0 0 0.13 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.12 0.08 0.22 0 0 0 0 0 0
Cytoplasm 0 0 0.06 0.09 0.09 0.08 0.07 0.07 0 0 0.05 0.07 0.1 0.2 0.23 0.14 0.21 0.11 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0.05 0.05 0.07 0 0 0 0 0 0
Endosome 0 0 0.07 0 0.12 0 0 0 0 0 0 0 0.13 0.2 0.22 0.11 0.08 0.09 0.06 0.05 0.05 0.08 0.07 0.09
Golgi 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.15 0.08 0 0.1 0 0 0 0
Mitochondria 0.76 0.85 0.63 0.68 0.59 0.81 0.9 0.77 0.91 0.91 0.89 0.84 0.58 0.32 0.24 0.18 0.22 0.09 0.54 0.71 0.74 0.67 0.66 0.62
Nucleus 0.31 0 0.11 0.14 0.11 0.1 0.06 0.11 0.08 0.07 0.12 0.09 0 0 0 0 0 0 0.29 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.06 0.06 0.06 0 0 0 0 0 0 0 0.05 0.08 0.15 0.1 0.1 0.08 0 0 0 0.08 0 0
SpindlePole 0 0 0.11 0.09 0.05 0 0 0.07 0 0 0 0 0.06 0 0 0.09 0.08 0.07 0 0 0 0 0 0
Vac/Vac Membrane 0.08 0.15 0 0 0.12 0.07 0.05 0.05 0.08 0 0 0.09 0.17 0.16 0.26 0.3 0.12 0.15 0 0.05 0 0 0.06 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 2 4 1 0 1 0 0 0 0 1 0 7 3 0 4 3 8 1 2 1 5 10 13
Bud 4 1 7 7 6 8 19 11 13 9 16 11 2 3 2 4 3 14 0 0 1 0 2 4
Bud Neck 0 0 0 0 0 0 3 1 0 0 0 1 1 0 0 0 0 0 0 0 1 2 5 7
Bud Site 1 0 0 1 0 1 0 2 5 6 4 2 0 0 0 0 3 2 – – – – – –
Cell Periphery 3 4 5 3 2 4 0 1 1 0 1 3 2 5 7 19 9 24 0 0 0 0 0 1
Cytoplasm 7 3 9 18 18 23 22 20 7 6 13 17 18 36 55 22 22 12 0 0 0 3 2 4
Endoplasmic Reticulum 3 4 3 2 0 5 3 0 1 0 3 0 5 19 3 7 5 8 0 0 0 0 1 3
Endosome 1 4 10 6 25 7 1 7 1 0 0 0 24 37 53 16 9 10 15 5 8 17 21 30
Golgi 0 5 0 0 1 1 0 0 0 0 0 0 4 3 6 13 16 9 4 11 3 6 11 10
Mitochondria 194 80 88 131 121 241 302 216 259 190 240 212 109 59 58 28 23 10 141 77 137 150 218 211
Nucleus 79 2 16 27 23 29 20 31 22 14 33 22 6 3 1 6 3 4 75 2 8 2 1 2
Nuclear Periphery 2 0 0 0 0 3 5 2 6 4 8 2 0 1 0 1 0 0 0 0 0 0 1 4
Nucleolus 16 2 0 0 1 3 8 7 3 4 6 6 0 0 0 0 0 1 6 0 0 0 3 6
Peroxisomes 0 1 8 12 12 4 2 4 0 0 0 0 10 15 36 15 11 9 2 1 6 18 14 12
SpindlePole 3 0 16 17 10 11 15 19 11 4 3 10 11 7 5 13 9 8 0 1 2 4 8 5
Vac/Vac Membrane 21 14 6 6 24 21 16 13 22 7 12 22 31 29 62 45 13 16 11 5 8 9 19 16
Unique Cell Count 255 94 140 192 204 297 337 282 284 208 270 252 187 182 240 152 106 108 262 109 187 223 330 343
Labelled Cell Count 334 122 172 231 243 362 416 334 351 244 340 308 230 220 288 193 129 135 262 109 187 223 330 343


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 6.2 5.4 5.4 5.7 4.8 4.2 5.1 4.2 4.3 4.2 4.6 5.7 6.1 6.2 8.0 7.1 6.6 5.7 5.9 6.6
Std Deviation (1e-4) 0.8 1.0 1.1 1.8 1.7 1.4 1.3 1.4 1.1 0.9 1.5 1.5 1.0 1.0 1.5 2.1 1.7 1.5 1.2 1.6 1.9
Intensity Change (Log2) – – – 0.0 0.09 -0.17 -0.35 -0.07 -0.35 -0.32 -0.34 -0.22 0.08 0.18 0.21 0.58 0.41 0.3 0.1 0.13 0.29

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.7
Bud -0.6 -1.0 0 0 -0.5 0 0 0 0 0 0 0 -1.1 0 2.2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 2.8 1.6 4.5
Cytoplasm 1.0 0.8 0.5 0 0.3 -2.0 -1.6 -0.7 0.1 1.0 3.4 4.1 2.2 3.4 1.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 2.9 0 0 0 0
Endosome -1.7 1.5 0 0 -2.3 0 0 0 0 1.7 3.3 3.8 1.0 0.4 0.6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 3.5 4.8 0
Mitochondria 1.0 -0.7 0 0 3.0 0 0 0 0 -0.8 -5.4 -7.5 -7.8 -6.4 -8.6
Nucleus 0.7 0 -0.5 -2.1 -0.1 -1.2 -1.5 0.2 -0.9 -2.9 -3.7 -5.0 -2.4 -2.5 -2.2
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.2 0.1 0 0 0 0 0 0 0 -0.1 0.9 2.7 1.3 1.4 0.8
SpindlePole -0.8 -2.2 0 0 -1.6 0 0 0 0 -1.8 -2.6 -3.8 -0.8 -0.8 -1.1
Vacuole -0.6 2.4 1.1 0.2 0.2 1.3 -0.4 0.1 1.6 3.5 3.3 5.3 5.7 2.3 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.1797 1.2433 1.0192 0.8205 0.2014 1.0331 2.3131 1.7394 1.7493 1.4304 1.7445 1.6784 2.3089 1.8766 1.8433 1.9155 1.8844 1.8277
Actin 0.0196 0.0042 0.0041 0.0017 0.0186 0.004 0.0151 0.0097 0.0037 0.0009 0.0039 0.0024 0.0114 0.0102 0.0086 0.0012 0.0006 0.0159
Bud 0.0007 0.0047 0.0023 0.0006 0.0011 0.0007 0.0022 0.002 0.0024 0.0014 0.0013 0.0009 0.0028 0.0011 0.0015 0.0002 0.0001 0.0027
Bud Neck 0.0005 0.0007 0.0003 0.0003 0.0037 0.0004 0.0017 0.0008 0.003 0.0002 0.0005 0.0007 0.0022 0.0004 0.0007 0 0.0001 0.0007
Bud Periphery 0.0029 0.0036 0.0035 0.0017 0.0022 0.001 0.0021 0.004 0.004 0.0163 0.0035 0.0014 0.0024 0.0026 0.0026 0.0007 0.0003 0.0017
Bud Site 0.0014 0.0212 0.0027 0.0004 0.0033 0.0009 0.0045 0.0135 0.005 0.0006 0.0022 0.001 0.003 0.004 0.0074 0.0005 0.0001 0.0004
Cell Periphery 0.0004 0.0007 0.0007 0.0002 0.0019 0.0002 0.0015 0.0007 0.0005 0.0021 0.0003 0.0002 0.0007 0.0005 0.0007 0.0001 0.0001 0.0003
Cytoplasm 0.0021 0.0034 0.0032 0.0015 0.002 0.004 0.0044 0.0034 0.0042 0.0017 0.0063 0.0015 0.0017 0.0053 0.0006 0.0001 0.0003 0.0022
Cytoplasmic Foci 0.0206 0.0359 0.0176 0.0126 0.0183 0.0188 0.0275 0.0277 0.0202 0.0567 0.0314 0.0225 0.0242 0.0194 0.0112 0.0107 0.0141 0.0123
Eisosomes 0.0004 0.0003 0.0003 0.0001 0.0024 0.0002 0.0015 0.0003 0.0002 0.0005 0.0004 0.0001 0.0004 0.0003 0.0004 0.0001 0.0001 0.0003
Endoplasmic Reticulum 0.0021 0.0007 0.0027 0.0005 0.0006 0.0011 0.0018 0.0007 0.0008 0.0003 0.0043 0.0012 0.0012 0.0011 0.0002 0.0001 0.0003 0.0018
Endosome 0.0748 0.0767 0.0424 0.0758 0.0199 0.0365 0.0807 0.0867 0.0516 0.0822 0.0536 0.0379 0.0519 0.0425 0.0294 0.0103 0.0384 0.0387
Golgi 0.0407 0.0521 0.0259 0.0548 0.0212 0.0383 0.0551 0.0451 0.0296 0.0282 0.0355 0.0373 0.0509 0.0619 0.0391 0.0486 0.0441 0.0522
Lipid Particles 0.057 0.0329 0.0197 0.0048 0.0332 0.0137 0.0429 0.0143 0.013 0.0185 0.0049 0.0135 0.018 0.0066 0.0037 0.0007 0.0006 0.0125
Mitochondria 0.6992 0.7001 0.804 0.827 0.7951 0.8474 0.6978 0.7277 0.8174 0.7255 0.809 0.8235 0.7866 0.8064 0.8703 0.8928 0.8691 0.8313
None 0.004 0.0026 0.0151 0.0003 0.0073 0.0007 0.006 0.0066 0.003 0.0025 0.0043 0.0017 0.0037 0.001 0.0002 0.0001 0.0001 0.0006
Nuclear Periphery 0.0117 0.0005 0.0048 0.0001 0.0055 0.0024 0.0049 0.0005 0.0016 0.0003 0.0053 0.0042 0.002 0.0008 0.0001 0 0.0003 0.0007
Nucleolus 0.0013 0.0011 0.0013 0.0001 0.0019 0.0002 0.003 0.0009 0.0011 0.0004 0.0006 0.0009 0.0012 0.0004 0.0008 0 0 0.0009
Nucleus 0.0058 0.0007 0.0018 0.0002 0.0031 0.0004 0.0027 0.0007 0.0007 0.0002 0.0018 0.0013 0.0008 0.0008 0.0006 0 0 0.0023
Peroxisomes 0.0396 0.0445 0.0392 0.0109 0.0392 0.0244 0.0283 0.0377 0.0295 0.0534 0.0245 0.0412 0.0171 0.0297 0.0165 0.0315 0.0031 0.0158
Punctate Nuclear 0.0024 0.0006 0.0021 0 0.0144 0.0003 0.0057 0.0004 0.0016 0.0013 0.0008 0.0013 0.002 0.0001 0.0001 0 0 0.0004
Vacuole 0.0071 0.008 0.0034 0.0028 0.0025 0.0022 0.0059 0.0114 0.0042 0.0042 0.0032 0.0019 0.0097 0.0024 0.003 0.0006 0.0034 0.0031
Vacuole Periphery 0.0059 0.005 0.0029 0.0035 0.0026 0.0021 0.0046 0.0051 0.0027 0.0026 0.0023 0.0032 0.0058 0.0021 0.0024 0.0014 0.025 0.0033

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2.8645 6.1456 4.5603 9.3675 12.6274 8.0162 13.7223 17.1252 17.5136 11.2695
Translational Efficiency 1.4292 1.1868 1.9524 1.4198 0.4626 1.1067 0.7982 0.9067 0.8727 0.6894

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
154 535 1901 325 1513 2097 246 476 1667 2632 2147 801

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 733.85 762.84 863.53 916.68 701.35 794.87 1004.68 830.09 704.35 788.36 879.70 865.22
Standard Deviation 80.01 107.71 104.03 106.40 83.58 101.30 112.66 118.13 83.79 103.44 114.27 121.22
Intensity Change Log 2 — 0.055895 0.234761 0.320933 — 0.180584 0.518530 0.243133 — 0.118175 0.380405 0.283438

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000879 0.004014 0.004311 0.028525 0.000990 0.000890 0.011726 0.003351 0.000980 0.001525 0.005161 0.013565
Bud Neck 0.023684 0.013550 0.014862 0.011098 0.015841 0.004874 0.024200 0.030249 0.016566 0.006638 0.015932 0.022479
Bud Site 0.012736 0.043072 0.062908 0.158966 0.024001 0.012340 0.073533 0.065344 0.022960 0.018587 0.064125 0.103331
Cell Periphery 0.001153 0.001110 0.000183 0.001166 0.000562 0.000250 0.000397 0.000520 0.000617 0.000425 0.000208 0.000782
Cytoplasm 0.015244 0.008766 0.043424 0.027671 0.028323 0.004588 0.035538 0.036320 0.027115 0.005437 0.042520 0.032811
Cytoplasmic Foci 0.082340 0.049566 0.117544 0.104666 0.101749 0.041376 0.171650 0.091618 0.099956 0.043041 0.123744 0.096912
Eisosomes 0.000167 0.000126 0.000094 0.000216 0.000211 0.000065 0.000244 0.000112 0.000207 0.000077 0.000111 0.000154
Endoplasmic Reticulum 0.002725 0.000747 0.006751 0.005100 0.001476 0.000288 0.010299 0.002051 0.001591 0.000382 0.007157 0.003288
Endosome 0.101319 0.092619 0.061014 0.096654 0.066562 0.080567 0.136764 0.146636 0.069773 0.083017 0.069693 0.126356
Golgi 0.120035 0.119909 0.076341 0.108016 0.121893 0.130775 0.078854 0.056722 0.121722 0.128567 0.076629 0.077534
Lipid Particles 0.010777 0.004194 0.002547 0.001585 0.007451 0.001910 0.011783 0.007550 0.007758 0.002374 0.003606 0.005130
Mitochondria 0.505722 0.547385 0.249980 0.181260 0.542534 0.646942 0.057724 0.272269 0.539133 0.626705 0.227951 0.235342
Mitotic Spindle 0.006826 0.014787 0.140939 0.065231 0.007373 0.013991 0.079372 0.056680 0.007322 0.014153 0.133885 0.060150
None 0.000257 0.000461 0.000580 0.000186 0.000663 0.000293 0.000356 0.001277 0.000625 0.000328 0.000554 0.000834
Nuclear Periphery 0.000436 0.000176 0.002029 0.000983 0.000120 0.000096 0.001789 0.000997 0.000149 0.000112 0.002001 0.000991
Nuclear Periphery Foci 0.000401 0.000720 0.002506 0.001233 0.000243 0.000201 0.003288 0.001351 0.000258 0.000306 0.002596 0.001303
Nucleolus 0.004929 0.002263 0.001787 0.000587 0.000948 0.000472 0.005172 0.001281 0.001316 0.000836 0.002175 0.000999
Nucleus 0.004285 0.002120 0.016395 0.005316 0.004176 0.000629 0.030119 0.007358 0.004186 0.000932 0.017967 0.006529
Peroxisomes 0.054288 0.053235 0.026344 0.101186 0.036448 0.020885 0.122605 0.050166 0.038096 0.027461 0.037373 0.070867
Vacuole 0.021203 0.024029 0.127178 0.075204 0.019764 0.018597 0.120629 0.127227 0.019897 0.019701 0.126427 0.106119
Vacuole Periphery 0.030592 0.017150 0.042284 0.025149 0.018672 0.019970 0.023960 0.040922 0.019773 0.019396 0.040184 0.034523

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.78 -5.84 -5.55 -4.83 -4.83 0.37 -5.53 -2.40 -2.45 3.83 -1.77 -9.15 -5.89 -5.59 -3.79
Bud Neck 1.54 1.32 2.01 0.86 2.73 7.11 -2.88 -3.36 -6.29 -1.25 6.30 -0.02 -2.05 -6.23 -2.23
Bud Site -4.96 -11.98 -12.52 -9.47 -8.37 5.43 -7.02 -6.80 -8.97 0.99 1.99 -14.56 -13.06 -13.96 -6.10
Cell Periphery 0.09 2.45 -0.02 -0.13 -3.39 2.86 1.44 0.45 -3.23 -1.23 1.69 3.98 -0.95 -2.57 -4.48
Cytoplasm 1.10 -5.04 -2.04 -5.17 4.23 9.90 -1.74 -2.02 -7.03 0.07 9.61 -5.74 -1.98 -9.01 2.54
Cytoplasmic Foci 3.05 -3.19 -1.83 -7.71 1.76 15.38 -6.32 1.12 -8.72 6.44 15.39 -4.81 0.33 -12.26 4.54
Eisosomes 1.55 2.85 -1.52 -4.05 -5.99 6.70 -1.39 4.23 -6.75 6.45 6.48 4.63 2.35 -8.15 -4.21
Endoplasmic Reticulum 1.78 -3.70 -1.60 -4.10 1.71 4.50 -4.14 -1.63 -6.42 3.86 4.62 -10.69 -3.29 -6.33 6.20
Endosome 0.62 3.21 0.34 -0.39 -4.68 -3.40 -6.68 -8.86 -7.26 -0.99 -3.40 0.43 -8.40 -6.52 -9.15
Golgi 0.01 3.12 0.75 1.06 -3.26 -1.48 5.22 10.42 12.64 1.97 -1.24 9.19 7.02 8.82 -0.34
Lipid Particles 1.75 2.45 2.78 1.43 2.36 4.70 -2.06 -0.17 -2.31 1.34 4.65 3.59 1.29 -1.84 -0.97
Mitochondria -1.25 8.74 10.04 17.47 4.18 -9.16 40.49 16.25 23.67 -12.43 -8.14 30.40 22.82 32.29 -0.55
Mitotic Spindle -2.34 -23.63 -6.57 -5.70 7.56 -4.68 -7.16 -7.80 -6.74 1.71 -5.29 -26.68 -10.28 -8.90 10.37
None -2.75 -6.63 1.82 4.09 10.67 1.76 1.13 -0.65 -1.10 -0.95 1.57 0.32 -0.33 -0.94 -0.47
Nuclear Periphery 1.16 -4.89 -0.66 -1.00 1.34 0.82 -3.08 -2.74 -2.82 1.30 0.97 -7.48 -2.24 -2.34 2.39
Nuclear Periphery Foci -0.68 -4.90 -1.13 -0.46 1.64 0.48 -3.39 -1.62 -1.67 2.28 -0.48 -6.31 -2.08 -1.89 2.35
Nucleolus 0.62 0.72 1.03 1.42 3.54 1.80 -4.06 -1.24 -3.56 3.77 0.96 -1.91 0.63 -0.67 3.97
Nucleus 1.13 -6.07 -0.34 -1.10 3.95 4.56 -5.15 -2.38 -4.90 4.35 4.43 -9.64 -1.77 -4.10 6.18
Peroxisomes 0.09 3.01 -3.29 -3.89 -6.79 5.33 -7.35 -2.42 -5.47 5.70 3.62 0.27 -5.51 -7.63 -5.78
Vacuole -0.46 -16.40 -5.96 -6.56 6.47 0.74 -9.46 -13.23 -13.42 -0.28 0.15 -28.95 -14.81 -14.97 2.76
Vacuole Periphery 2.27 -1.79 0.81 -1.90 3.83 -0.88 -0.89 -5.23 -4.97 -3.06 0.25 -9.23 -4.63 -4.96 1.71
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
Localization
Cell Percentages mitochondrion (92%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Rci37

Rci37


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rci37-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available