Standard name
Human Ortholog
Description Methyltransferase required for m3U2634 methylation of the 25S rRNA; S-adenosylmethionine-dependent; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.08 0.05 0.05 0.05 0.05 0 0.06 0 0.13 0.1 0.21 0.05 0.09 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0.1 0.07
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.23 0 0 0.09 0.07 0.4 0.55 0.37 0.63 0.52 0.72 0.45 0.11 0 0 0 0 0.05 0 0 0 0 0.06 0.08
Nucleus 0.95 0.91 0.96 0.65 0.78 0.68 0.61 0.61 0.63 0.67 0.57 0.69 0.64 0.51 0.37 0.6 0.53 0.53 0.89 0.85 0.8 0.58 0.32 0.31
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
Nucleolus 0 0.06 0 0.29 0.09 0.07 0.14 0.13 0.11 0.07 0.08 0.07 0.3 0.46 0.39 0.35 0.35 0.41 0 0 0.07 0.16 0.19 0.14
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.1 0.07 0.06 0 0.07 0 0 0 0 0.09 0.13 0.18 0 0 0 0 0 0 0 0 0.05
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0.1 0.19 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 0 0 0 0 1 2 5 4 6 5 8 3 0 0 0 0 0 0 2 0 1 0 1 2
Bud Neck 0 0 0 0 1 1 0 6 0 4 0 0 0 2 0 0 0 0 0 0 0 0 0 3
Bud Site 0 1 0 1 0 9 6 6 16 13 11 13 1 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 4 4 7 7 30 16 22 21 24 12 18 9 15 18 43 9 18 12 0 0 0 1 1 3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 1 0 1 2 1 3 2 2 3 0 0 0 0 1 0
Endosome 0 0 0 4 12 6 5 4 1 3 0 7 0 5 18 3 3 2 3 0 2 2 15 12
Golgi 0 0 0 1 0 0 0 0 0 0 0 0 0 1 1 1 3 0 1 1 0 0 1 0
Mitochondria 67 2 6 21 27 129 249 156 274 212 224 181 13 3 3 3 8 8 1 0 2 1 8 15
Nucleus 279 117 188 157 300 219 276 256 274 271 178 277 74 94 74 112 112 81 263 107 153 42 48 58
Nuclear Periphery 2 0 1 1 1 0 4 8 16 2 3 6 0 2 0 3 2 0 1 0 0 0 3 9
Nucleolus 3 8 2 69 35 23 64 56 46 30 25 29 35 86 79 65 73 63 9 4 13 11 28 25
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0
SpindlePole 1 0 1 23 26 19 13 31 11 13 3 9 10 24 36 5 5 2 0 0 0 3 6 9
Vac/Vac Membrane 3 6 0 2 11 4 5 7 9 12 5 14 1 1 1 7 9 5 6 10 12 7 29 33
Unique Cell Count 293 128 196 241 387 322 451 419 437 405 313 402 116 186 201 187 210 153 295 127 192 73 152 185
Labelled Cell Count 359 138 205 286 444 428 649 555 677 578 475 549 151 237 258 210 236 177 295 127 192 73 152 185


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.8 6.7 6.0 5.8 5.9 4.6 4.3 4.7 3.9 4.3 3.7 4.5 5.8 6.6 6.5 11.2 10.8 10.3 5.9 6.9 7.3
Std Deviation (1e-4) 0.8 1.5 1.1 1.1 1.8 1.2 1.2 1.1 0.8 0.8 0.8 1.0 1.2 1.7 2.1 2.4 2.5 2.5 1.4 2.0 1.8
Intensity Change (Log2) – – – -0.05 -0.03 -0.4 -0.49 -0.36 -0.64 -0.48 -0.69 -0.43 -0.07 0.13 0.12 0.89 0.84 0.77 -0.04 0.21 0.27


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.4 2.0 0.7 0.7 0.8 1.0 -0.4 1.1 -0.9 3.1 2.4 5.4 0.6 2.1 1.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 4.3 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.4 1.9 0 0 0 0 0 0 0 2.9 0 0 0 0.4 1.0
Nucleus -7.8 -5.7 -7.5 -9.0 -9.0 -8.7 -7.8 -9.5 -7.5 -7.5 -10.1 -12.4 -8.6 -9.8 -9.5
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 7.8 3.8 0 0 0 0 0 0 0 7.7 10.5 9.5 8.7 8.8 9.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 4.1 3.4 0 0 0 0 0 0 0 0 4.9 6.0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.5699 1.6636 1.4191 1.1878 0.9356 1.4734 2.4888 2.0407 1.6432 1.2621 1.5633 1.8026 1.2027 1.6286 1.6625 1.6944 1.3534 1.4441
Actin 0.0057 0 0.0011 0 0.0002 0.0002 0.0464 0.0001 0.0071 0.0342 0 0.0017 0.0068 0.0001 0.0039 0.0359 0.0282 0.0001
Bud 0.0003 0.0001 0.0002 0 0 0 0.0003 0.0001 0.0002 0.0001 0 0.0001 0.0002 0.0001 0.0004 0.0001 0.0001 0.0002
Bud Neck 0.001 0.0005 0.0021 0.0003 0.0029 0.0009 0.0079 0.0005 0.0009 0.0042 0.0012 0.0014 0.0008 0.0005 0.0009 0.0006 0.0006 0.0016
Bud Periphery 0.0003 0.0001 0.0005 0.0001 0.0001 0.0001 0.0005 0.0003 0.0004 0.0002 0.0001 0.0002 0.0004 0.0002 0.0004 0.0003 0.0002 0.0003
Bud Site 0.0005 0.0003 0.0024 0.0002 0.0002 0.0001 0.0013 0.0007 0.0013 0.0007 0.0001 0.0002 0.0011 0.0004 0.0005 0.0006 0.0003 0.0002
Cell Periphery 0.0001 0.0001 0.0005 0 0 0 0.0002 0.0002 0.0002 0.0001 0 0.0001 0.0001 0.0001 0.0002 0.0002 0 0.0001
Cytoplasm 0.0015 0.0002 0.0011 0.0001 0.0009 0.0001 0.0094 0.0001 0.0021 0.0003 0.0002 0.0016 0.0022 0.0002 0.0011 0.0005 0.0008 0.0034
Cytoplasmic Foci 0.0024 0 0.0015 0.0001 0.0001 0.0002 0.0084 0.0001 0.0067 0.001 0 0.0057 0.0034 0 0.003 0.0018 0.0083 0.0003
Eisosomes 0.0001 0 0.0001 0 0 0 0.0003 0 0.0001 0.0003 0 0 0.0002 0 0.0001 0.0003 0.0001 0
Endoplasmic Reticulum 0.0009 0 0.0005 0 0.0002 0.0001 0.0053 0 0.0019 0.0004 0 0.0008 0.0013 0 0.0007 0.0015 0.0004 0.0001
Endosome 0.0057 0.0003 0.0024 0.0001 0.0004 0.0009 0.0347 0.0003 0.008 0.0016 0.0001 0.0103 0.0086 0.0001 0.0035 0.0033 0.0053 0.0002
Golgi 0.0013 0 0.0009 0 0 0.0001 0.0084 0.0001 0.003 0.0019 0 0.0007 0.0024 0 0.0015 0.0033 0.0078 0
Lipid Particles 0.0077 0.0002 0.0081 0.0005 0.0001 0.0012 0.0105 0.0006 0.0064 0.0013 0 0.0019 0.0061 0.0002 0.0016 0.0087 0.0143 0.0002
Mitochondria 0.0017 0.0004 0.0016 0.0003 0.0002 0.0002 0.0031 0.001 0.0038 0.0005 0.0005 0.0004 0.0095 0.0006 0.0013 0.002 0.0016 0.0002
None 0.0014 0.0001 0.0004 0.0002 0.0003 0.0001 0.0064 0.0002 0.0029 0.0004 0.0003 0.0017 0.0036 0.0001 0.0006 0.0008 0.0005 0.0001
Nuclear Periphery 0.0189 0.0066 0.0137 0.0009 0.0042 0.0073 0.0409 0.0073 0.0092 0.0027 0.0044 0.0156 0.0058 0.0035 0.005 0.0278 0.0048 0.0011
Nucleolus 0.194 0.268 0.2859 0.2153 0.3031 0.2846 0.2306 0.3074 0.3086 0.2508 0.1074 0.3109 0.2268 0.3595 0.3869 0.2133 0.0704 0.3221
Nucleus 0.7146 0.7171 0.6201 0.7515 0.6784 0.6885 0.5584 0.6719 0.617 0.6947 0.8802 0.6267 0.6972 0.63 0.5593 0.6591 0.8104 0.6534
Peroxisomes 0.0019 0 0.0012 0.0001 0 0.0001 0.0027 0.0003 0.0083 0.0008 0 0.0005 0.0087 0 0.0037 0.0061 0.0168 0
Punctate Nuclear 0.0374 0.0048 0.0514 0.0301 0.0083 0.0147 0.0201 0.0072 0.0098 0.0035 0.0046 0.0179 0.0126 0.0031 0.0234 0.032 0.0283 0.0157
Vacuole 0.0015 0.0007 0.0028 0.0002 0.0003 0.0002 0.0021 0.0009 0.0016 0.0003 0.0004 0.0012 0.0014 0.0006 0.0015 0.0008 0.0005 0.0006
Vacuole Periphery 0.0012 0.0003 0.0014 0.0001 0.0001 0.0003 0.0018 0.0005 0.0007 0.0001 0.0004 0.0006 0.0009 0.0005 0.0007 0.0011 0.0002 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.6452 17.5616 10.8596 14.1196 19.1031 11.9987 11.5911 13.3161 8.5148 18.2776
Translational Efficiency 1.6264 1.51 1.8782 1.1444 1.1501 1.8138 1.7445 0.814 1.4068 1.1037

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1585 1150 2954 1724 1041 1949 1430 1255 2626 3099 4384 2979

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 786.90 809.74 976.08 996.87 698.02 870.93 983.48 1020.62 751.67 848.22 978.49 1006.88
Standard Deviation 101.44 153.34 140.39 146.94 113.49 116.85 132.88 159.66 114.92 134.86 138.03 152.88
Intensity Change Log 2 — 0.041278 0.310819 0.341225 — 0.319288 0.494627 0.548106 — 0.178651 0.400145 0.442176

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000099 0.000517 0.000403 0.000826 0.000249 0.000275 0.000455 0.001054 0.000158 0.000365 0.000420 0.000922
Bud Neck 0.002992 0.010406 0.025414 0.040250 0.003783 0.008572 0.019238 0.052584 0.003306 0.009252 0.023400 0.045446
Bud Site 0.000348 0.001702 0.000860 0.003937 0.000391 0.000748 0.000722 0.005074 0.000365 0.001102 0.000815 0.004416
Cell Periphery 0.000096 0.000199 0.000087 0.000101 0.000123 0.000071 0.000045 0.000102 0.000107 0.000118 0.000073 0.000102
Cytoplasm 0.004695 0.008591 0.000743 0.004599 0.006845 0.002274 0.000997 0.005354 0.005547 0.004618 0.000826 0.004917
Cytoplasmic Foci 0.000452 0.001479 0.000006 0.000985 0.000642 0.001001 0.000029 0.002399 0.000528 0.001179 0.000014 0.001581
Eisosomes 0.000012 0.000028 0.000030 0.000028 0.000020 0.000025 0.000023 0.000038 0.000015 0.000026 0.000028 0.000032
Endoplasmic Reticulum 0.004851 0.006743 0.006216 0.007192 0.004092 0.005542 0.004832 0.007202 0.004550 0.005988 0.005765 0.007196
Endosome 0.000386 0.001229 0.000249 0.001870 0.000493 0.000693 0.000214 0.003050 0.000429 0.000892 0.000238 0.002367
Golgi 0.000036 0.001065 0.000031 0.001154 0.000122 0.000791 0.000052 0.002255 0.000070 0.000893 0.000038 0.001618
Lipid Particles 0.000162 0.000575 0.000020 0.000121 0.000436 0.000558 0.000049 0.000333 0.000271 0.000564 0.000030 0.000210
Mitochondria 0.001330 0.002628 0.001147 0.003934 0.000774 0.003149 0.000849 0.004032 0.001110 0.002956 0.001050 0.003975
Mitotic Spindle 0.000176 0.001164 0.000279 0.017572 0.000315 0.004482 0.000558 0.022343 0.000231 0.003251 0.000370 0.019582
None 0.003106 0.018611 0.000961 0.003230 0.010320 0.001549 0.001236 0.002439 0.005966 0.007880 0.001051 0.002897
Nuclear Periphery 0.001239 0.000871 0.001185 0.004442 0.000968 0.001014 0.000569 0.003014 0.001131 0.000961 0.000984 0.003841
Nuclear Periphery Foci 0.000173 0.000842 0.000090 0.001624 0.000646 0.000436 0.000116 0.001948 0.000360 0.000587 0.000099 0.001761
Nucleolus 0.024345 0.067365 0.025316 0.081486 0.079989 0.061734 0.047152 0.134721 0.046403 0.063823 0.032439 0.103913
Nucleus 0.953730* 0.873599* 0.935311* 0.817449* 0.888450* 0.904866* 0.921827* 0.738669* 0.927852* 0.893263* 0.930912* 0.784260*
Peroxisomes 0.000141 0.000732 0.000086 0.000378 0.000335 0.000733 0.000184 0.001019 0.000218 0.000732 0.000118 0.000648
Vacuole 0.001077 0.001119 0.001198 0.005569 0.000752 0.001086 0.000693 0.009008 0.000948 0.001098 0.001033 0.007018
Vacuole Periphery 0.000555 0.000535 0.000367 0.003251 0.000255 0.000401 0.000159 0.003361 0.000436 0.000451 0.000299 0.003297

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.40 -27.55* -24.80* -6.57 -15.15 -0.79 -7.56 -8.99 -8.67 -6.99 -7.66 -19.05 -17.12 -12.07 -12.12
Bud Neck -7.52 -21.66 -25.25 -20.09 -11.73 -6.37 -16.66 -24.77 -22.47 -16.53 -9.68 -26.95 -35.19 -30.43 -19.46
Bud Site -4.68 -4.47 -7.13 -4.29 -6.07 -2.81 -4.50 -12.19 -11.47 -11.13 -5.41 -6.00 -12.88 -10.71 -11.41
Cell Periphery -2.32 0.65 -0.12 2.33 -0.97 2.16 4.05 1.03 -1.80 -5.67 -0.64 2.77 0.57 1.02 -3.15
Cytoplasm -2.90 5.31 -0.57 2.54 -6.42 3.42 4.39 1.00 -3.19 -4.65 0.88 6.93 0.25 -0.72 -8.12
Cytoplasmic Foci -2.15 1.95 -0.67 1.77 -3.00 -1.18 3.76 -2.19 -1.53 -3.12 -2.41 3.38 -2.23 -0.12 -4.06
Eisosomes -9.14 -14.82 -15.93 -0.06 -0.25 -2.15 -4.06 -11.76 -5.75 -9.35 -7.05 -14.32 -19.40 -4.25 -5.87
Endoplasmic Reticulum -3.56 -3.05 -3.97 -0.03 -1.76 -3.49 -2.42 -5.15 -2.29 -3.85 -4.15 -4.08 -6.21 -2.20 -3.56
Endosome -3.07 1.41 -3.41 -0.50 -3.81 -1.29 3.03 -3.98 -3.48 -4.55 -3.37 2.85 -5.25 -3.19 -5.92
Golgi -2.24 -0.53 -2.92 0.38 -2.91 -1.96 1.34 -2.54 -1.24 -2.67 -3.05 1.33 -3.76 -0.72 -3.86
Lipid Particles -2.19 4.91 0.40 2.26 -10.37 -0.42 2.44 0.51 0.79 -5.20 -1.63 3.67 0.51 1.90 -7.96
Mitochondria -1.74 0.17 -4.51 -2.15 -8.53 -3.25 -2.43 -11.79 -1.43 -11.12 -3.14 -0.15 -7.91 -2.16 -13.07
Mitotic Spindle -3.13 -1.14 -7.47 -6.95 -7.40 -3.62 -1.27 -7.72 -6.03 -7.33 -4.21 -1.54 -10.73 -8.55 -10.49
None -5.85 3.93 -0.22 5.76 -3.78 5.16 5.34 4.53 -3.34 -4.84 -1.62 6.53 3.60 4.65 -5.21
Nuclear Periphery 1.76 -0.14 -5.90 -6.67 -5.99 -0.36 2.10 -7.15 -7.17 -8.42 1.16 0.43 -8.35 -9.01 -8.73
Nuclear Periphery Foci -3.77 0.64 -2.58 -0.75 -2.67 0.99 2.69 -2.80 -3.45 -4.28 -2.19 2.67 -3.76 -2.79 -4.54
Nucleolus -10.85 -1.08 -14.67 -4.00 -14.34 3.70 4.97 -8.87 -12.63 -13.33 -6.00 4.31 -16.51 -11.80 -20.34
Nucleus 13.36 6.73 24.58 9.44 21.68 -2.57 -3.38 19.97 22.98 23.52 8.83 1.23 31.35 23.46 32.26
Peroxisomes -5.11 1.75 -5.75 2.57 -7.57 -1.92 2.21 -5.34 -2.15 -6.29 -3.85 3.12 -7.10 -0.38 -8.56
Vacuole -0.46 -0.54 -6.05 -6.50 -6.49 -1.67 -0.74 -8.03 -7.40 -7.93 -1.06 -0.80 -9.87 -9.70 -10.13
Vacuole Periphery 0.05 0.83 -3.06 -3.22 -3.48 -2.03 2.61 -4.61 -4.30 -4.79 -0.16 0.97 -4.94 -5.06 -5.42
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Methyltransferase required for m3U2634 methylation of the 25S rRNA; S-adenosylmethionine-dependent; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis
Localization
Cell Percentages nucleus (94%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Bmt5

Bmt5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bmt5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available