Standard name
Human Ortholog
Description Transcriptional repressor; binds promoter sequences of cyclin genes, CYS3, and SMF2; not expressed during log phase of growth, but induced by stress or starvation during mitosis, and late in meiosis; represses 15% of all yeast genes as cells transition to quiescence; important for maintaining G1 arrest and for longevity of quiescent cells; member of Swi4p/Mbp1p family; phosphorylated by Cdc28p; relative distribution to nucleus increases upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.91 0.98 0.95 0.52 0.17 0.11 0.05 0 0 0 0 0.85 0.84 0.76 0.59 0.6 0.66 0.77 0.67 0.67 0.67 0.83 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.23 0.16 0.17 0.21 0.13 0.27 0.13 0 0 0 0.09 0 0.05 0.09 0.09 0.13 0.13 0 0
Nucleus 0 0 0 0 0.34 0.65 0.78 0.87 0.85 0.84 0.73 0.81 0.08 0.1 0.15 0.17 0.17 0.12 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0.08 0.15 0.16 0.28 0.26 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0.1 0 0 0 0 0 0 0 0.06 0.07 0.08 0.16 0.24 0.19 0 0.1 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 3 3 1 1
Bud 0 0 0 0 2 0 2 4 1 1 7 2 0 0 0 0 1 0 1 3 1 1 3 2
Bud Neck 0 1 5 1 5 1 1 4 0 3 0 1 0 1 0 2 0 0 1 3 0 0 0 0
Bud Site 0 0 0 0 0 3 3 5 10 9 17 4 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 0 0 3 0 0 0 0 0 0 0 0 0 0 0 3 2 2 1 0 2 2 0 1
Cytoplasm 253 277 225 158 99 40 32 18 6 6 9 5 161 181 176 245 200 268 200 239 139 139 190 174
Endoplasmic Reticulum 3 3 1 2 0 0 2 0 0 0 0 0 0 0 1 22 22 30 2 2 3 3 0 1
Endosome 0 0 1 2 4 1 2 0 3 0 0 0 2 5 9 29 17 22 3 4 3 3 1 3
Golgi 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 1 2 0 1 0 0 1 0
Mitochondria 7 8 0 3 7 54 47 63 67 45 120 47 1 1 0 36 7 21 22 33 27 27 7 8
Nucleus 0 7 2 2 66 152 221 332 276 293 325 288 16 21 35 72 56 50 0 9 4 4 3 0
Nuclear Periphery 0 0 0 0 0 0 3 0 6 2 3 2 0 0 1 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 1 3 5 31 49 57 122 92 0 1 0 2 2 2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0
SpindlePole 0 3 1 0 6 4 3 15 6 5 3 3 0 0 0 4 1 9 3 9 5 5 7 4
Vac/Vac Membrane 4 12 1 0 19 5 9 0 2 0 1 8 12 15 18 68 80 79 8 35 5 5 5 3
Unique Cell Count 263 306 229 166 192 233 285 381 326 349 443 357 189 216 231 418 334 408 259 360 207 207 229 211
Labelled Cell Count 268 311 236 172 210 263 331 472 426 421 607 452 192 225 240 485 390 485 259 360 207 207 229 211


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 4.3 4.9 4.7 5.5 4.8 5.2 5.8 5.5 6.2 5.8 6.2 5.3 5.5 5.3 5.8 5.9 5.4 4.9 5.0 5.2
Std Deviation (1e-4) 0.4 1.1 1.3 1.9 1.6 1.5 1.3 1.5 1.9 1.7 2.1 2.2 0.8 1.7 1.3 1.5 1.5 1.4 1.3 1.9 1.7
Intensity Change (Log2) – – – -0.05 0.16 -0.02 0.1 0.26 0.18 0.34 0.24 0.35 0.11 0.19 0.13 0.25 0.27 0.15 0.0 0.04 0.1


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – 0 0 0
Bud Neck – – – – – – – – – – – – 0 0 0
Bud Site – – – – – – – – – – – – 0 0 0
Cell Periphery – – – – – – – – – – – – 0 0 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – 0 0 0
Endosome – – – – – – – – – – – – 0 0 0
Golgi – – – – – – – – – – – – 0 0 0
Mitochondria – – – – – – – – – – – – 0 0 0
Nuclear Periphery – – – – – – – – – – – – 0 0 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – 0 0 0
Peroxisomes – – – – – – – – – – – – 0 0 0
SpindlePole – – – – – – – – – – – – 0 0 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – 0 0 0
Cytoplasm – – – – – – – – – – – – 0 0 0
Nucleus – – – – – – – – – – – – 0 0 0
Vacuole – – – – – – – – – – – – 6.2 7.8 6.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.8209 -0.9857 -0.9827 -0.7621 -1.3474 -1.0037 -0.3602 -0.281 -0.1486 -0.7928 0.0937 -0.2352 -0.9381 -0.4407 -0.7523 -0.7882 -0.9834 -1.0449
Actin 0.0496 0.0029 0.011 0.0002 0.0012 0.0009 0.0646 0.0003 0.0116 0.0232 0.0548 0.0039 0.0321 0.0015 0.0104 0.0371 0.0377 0.0012
Bud 0.0013 0.0002 0.0005 0.0001 0.002 0 0.001 0.001 0.0006 0.0061 0.0009 0.0008 0.0004 0.0014 0.0023 0.0003 0.0005 0.0007
Bud Neck 0.0173 0.0005 0.0005 0.0002 0.0001 0.0003 0.0022 0.0012 0.0007 0.0004 0.0014 0.0031 0.0014 0.0002 0.0011 0.0037 0.0004 0.002
Bud Periphery 0.0035 0.0003 0.001 0.0001 0.0082 0 0.0019 0.0016 0.0009 0.0242 0.0011 0.0013 0.0006 0.001 0.0009 0.0007 0.001 0.0005
Bud Site 0.0102 0.0063 0.0023 0.0003 0.0006 0.0001 0.0044 0.0026 0.0072 0.0012 0.0029 0.0004 0.0012 0.0031 0.0024 0.0002 0.0012 0.0002
Cell Periphery 0.0014 0.0005 0.0007 0 0.0005 0 0.0003 0.0001 0.0002 0.0003 0.0001 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.0306 0.071 0.046 0.0535 0.0986 0.074 0.069 0.0603 0.0669 0.0522 0.0462 0.0969 0.0662 0.114 0.1497 0.12 0.0555 0.2205
Cytoplasmic Foci 0.0537 0.0093 0.0143 0.0072 0.0024 0.0262 0.0131 0.0021 0.0066 0.0114 0.0212 0.01 0.0148 0.008 0.0115 0.0047 0.0127 0.0103
Eisosomes 0.0023 0.0004 0.0009 0.0001 0.0001 0.0003 0.0004 0 0.0002 0.0003 0.0002 0.0001 0.0006 0.0001 0.0002 0.0002 0.0006 0.0001
Endoplasmic Reticulum 0.0082 0.0022 0.0044 0.0008 0.003 0.0011 0.0038 0.0012 0.0014 0.0011 0.0034 0.0031 0.0028 0.0021 0.0022 0.0064 0.0008 0.003
Endosome 0.034 0.0035 0.0129 0.0555 0.0023 0.0059 0.015 0.0011 0.0037 0.0022 0.0414 0.0076 0.0067 0.0018 0.0033 0.0076 0.0029 0.0031
Golgi 0.0105 0.0015 0.0073 0.0027 0.0001 0.0045 0.007 0.0001 0.0011 0.001 0.0066 0.0017 0.002 0.0002 0.001 0.0026 0.0032 0.0001
Lipid Particles 0.0337 0.0041 0.0061 0.0021 0.0003 0.0076 0.013 0.0002 0.0012 0.001 0.0057 0.0076 0.0036 0.0005 0.0011 0.0012 0.0078 0.0003
Mitochondria 0.0256 0.0012 0.0122 0.0006 0.0014 0.0006 0.0124 0.0004 0.0194 0.0032 0.0019 0.0023 0.0022 0.0006 0.0015 0.0007 0.0121 0.0009
None 0.638 0.8643 0.8282 0.8661 0.8223 0.8649 0.5717 0.6188 0.6394 0.6876 0.5979 0.4826 0.7343 0.7855 0.7015 0.6655 0.6213 0.5667
Nuclear Periphery 0.0165 0.0019 0.0091 0.0009 0.0222 0.0008 0.0104 0.0047 0.004 0.0279 0.0098 0.0069 0.0075 0.0032 0.007 0.0084 0.0019 0.0037
Nucleolus 0.002 0.0005 0.0005 0.0002 0.0004 0.0003 0.003 0.0038 0.0039 0.0023 0.0053 0.0107 0.0042 0.0025 0.0029 0.0006 0.0008 0.0017
Nucleus 0.0133 0.0232 0.0307 0.0016 0.0293 0.0021 0.1716 0.2759 0.206 0.0972 0.1399 0.3066 0.081 0.0593 0.0844 0.1335 0.225 0.1698
Peroxisomes 0.0269 0.0017 0.0055 0.0003 0.0002 0.0065 0.0073 0.0001 0.0034 0.0048 0.0058 0.0034 0.0082 0.0004 0.0011 0.0003 0.0092 0.0002
Punctate Nuclear 0.0108 0.0035 0.0035 0.0009 0.0021 0.0035 0.0223 0.0219 0.0193 0.0511 0.0469 0.0477 0.0275 0.0122 0.0128 0.0048 0.0047 0.0128
Vacuole 0.0069 0.0008 0.0013 0.0055 0.0019 0.0003 0.0045 0.0023 0.0017 0.0008 0.0054 0.0028 0.002 0.002 0.0018 0.001 0.0004 0.0017
Vacuole Periphery 0.0034 0.0002 0.001 0.0011 0.0007 0.0001 0.0009 0.0003 0.0005 0.0006 0.0012 0.0006 0.0005 0.0003 0.0005 0.0005 0.0003 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 0.5676 2.0296 0.753 1.8103 1.4718 5.6728 3.0782 3.4626 4.0667 3.2289
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
61 895 1121 1262 2387 1509 691 162 2448 2404 1812 1424

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 611.49 659.27 876.80 823.13 658.49 658.39 818.75 827.17 657.32 658.72 854.66 823.59
Standard Deviation 76.85 96.42 112.81 133.38 70.81 95.48 113.53 128.51 71.35 95.84 116.55 132.84
Intensity Change Log 2 — 0.108541 0.519919 0.428791 — -0.000219 0.314261 0.329022 — 0.053172 0.416948 0.377923

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000051 0.000420 0.000742 0.001249 0.000139 0.000246 0.000429 0.000760 0.000137 0.000311 0.000623 0.001193
Bud Neck 0.007870 0.038760 0.011564 0.011926 0.019411 0.042058 0.003019 0.015814 0.019124 0.040830 0.008305 0.012369
Bud Site 0.001257 0.014982 0.002973 0.015889 0.004705 0.016674 0.001801 0.011325 0.004619 0.016044 0.002526 0.015370
Cell Periphery 0.000351 0.000291 0.000088 0.000300 0.000111 0.000193 0.000265 0.000202 0.000117 0.000229 0.000155 0.000288
Cytoplasm 0.339738* 0.376462* 0.020034 0.214135* 0.466133* 0.352777* 0.120154* 0.250851* 0.462983* 0.361595* 0.058215 0.218312*
Cytoplasmic Foci 0.095127 0.229811* 0.000475 0.009554 0.201274* 0.181907* 0.007931 0.018442 0.198629* 0.199742* 0.003318 0.010565
Eisosomes 0.000110 0.000133 0.000032 0.000045 0.000130 0.000131 0.000055 0.000062 0.000129 0.000132 0.000041 0.000047
Endoplasmic Reticulum 0.000611 0.000834 0.006221 0.004171 0.000969 0.001006 0.002952 0.004648 0.000960 0.000942 0.004974 0.004226
Endosome 0.004017 0.024095 0.000654 0.004042 0.006374 0.031510 0.001540 0.021786 0.006315 0.028750 0.000992 0.006061
Golgi 0.001457 0.002894 0.000077 0.001878 0.002590 0.005622 0.000489 0.012430 0.002562 0.004606 0.000234 0.003078
Lipid Particles 0.010232 0.008834 0.000641 0.001157 0.008865 0.012205 0.001545 0.002063 0.008899 0.010950 0.000986 0.001260
Mitochondria 0.009261 0.010547 0.001793 0.002831 0.005825 0.018637 0.000972 0.008911 0.005911 0.015625 0.001480 0.003523
Mitotic Spindle 0.000065 0.003332 0.002887 0.057874 0.002284 0.021536 0.004058 0.018324 0.002228 0.014759 0.003334 0.053375
None 0.030954 0.004759 0.003098 0.015800 0.003503 0.009648 0.016273 0.042064 0.004187 0.007828 0.008122 0.018788
Nuclear Periphery 0.000564 0.000878 0.001169 0.002363 0.000522 0.001220 0.001141 0.001736 0.000523 0.001093 0.001158 0.002292
Nuclear Periphery Foci 0.000311 0.000435 0.000361 0.001070 0.000231 0.000518 0.000414 0.001466 0.000233 0.000487 0.000381 0.001115
Nucleolus 0.006489 0.004047 0.004178 0.002818 0.001227 0.007310 0.004261 0.001235 0.001359 0.006095 0.004210 0.002638
Nucleus 0.480220* 0.184644* 0.936180* 0.620353* 0.237416* 0.194992* 0.816315* 0.515167* 0.243466* 0.191140* 0.890469* 0.608386*
Peroxisomes 0.002810 0.021958 0.000223 0.001307 0.006412 0.014060 0.000383 0.000275 0.006323 0.017001 0.000284 0.001190
Vacuole 0.006515 0.069999 0.006419 0.029620 0.031170 0.083621 0.015800 0.069999 0.030556 0.078550 0.009997 0.034214
Vacuole Periphery 0.001992 0.001883 0.000192 0.001619 0.000708 0.004128 0.000204 0.002440 0.000740 0.003292 0.000197 0.001712

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.37 -16.59 -4.63 -2.79 -0.53 -2.53 -4.06 -3.53 -3.23 -2.03 -3.63 -10.88 -4.81 -3.94 -1.35
Bud Neck -6.98 -1.78 -1.96 7.46 -0.30 -8.43 11.10 3.22 8.73 -1.70 -9.51 6.51 3.98 13.18 -3.04
Bud Site -6.62 -3.13 -6.79 0.91 -5.25 -7.07 3.25 -1.57 1.46 -2.25 -8.12 2.21 -4.64 1.97 -6.02
Cell Periphery 0.47 4.48 2.09 0.34 -9.03 -4.78 -3.83 -2.95 1.17 1.82 -1.95 -2.15 -7.51 0.01 -4.55
Cytoplasm -0.77 8.06 4.86 20.26 -20.23 12.72 43.39 18.15 11.00 -3.30 13.21 66.98 40.92 26.78 -15.37
Cytoplasmic Foci -7.80 6.03 5.67 30.63 -6.83 2.96 42.84 38.01 30.95 -1.52 -0.15 44.94 43.59 45.59 -4.28
Eisosomes -1.41 4.01 2.54 10.62 -7.24 -0.09 8.99 2.52 2.65 -4.27 -0.47 12.80 9.18 12.54 -5.96
Endoplasmic Reticulum -1.37 -19.35 -17.84 -18.15 0.82 -0.21 -10.29 -8.52 -8.53 -4.46 -0.03 -19.17 -18.16 -19.64 -2.42
Endosome -8.34 2.48 0.95 10.33 -4.88 -13.24 9.27 -0.03 6.21 -1.40 -15.41 11.64 4.73 17.31 -3.81
Golgi -1.20 1.28 0.58 3.45 -1.64 -3.16 5.71 -0.08 1.33 -1.29 -3.01 7.71 3.01 4.91 -1.86
Lipid Particles 0.46 3.77 3.57 9.34 -3.57 -2.86 10.47 10.11 10.33 -0.68 -2.27 12.54 12.38 14.40 -1.40
Mitochondria -0.20 1.48 1.36 6.58 -1.08 -7.14 8.16 1.69 6.51 -1.02 -7.45 6.66 5.43 11.04 -2.29
Mitotic Spindle -4.48 -3.68 -9.80 -8.89 -7.60 -7.53 -2.34 -2.75 -0.31 -2.01 -7.30 -3.10 -9.52 -5.90 -7.93
None 2.28 2.43 1.80 -4.76 -7.36 -4.18 -4.50 -2.75 -1.36 -0.70 -3.44 -2.65 -5.99 -2.29 -3.33
Nuclear Periphery -1.85 -6.61 -13.88 -13.60 -10.25 -7.61 -10.68 -8.22 -5.89 -4.67 -7.97 -15.31 -18.90 -14.30 -11.30
Nuclear Periphery Foci -0.78 -1.09 -3.62 -3.52 -3.27 -3.73 -3.33 -4.37 -3.50 -2.94 -4.67 -4.54 -4.96 -3.89 -3.54
Nucleolus 1.28 1.06 2.29 2.06 3.07 -7.18 -4.01 -0.13 6.60 3.41 -8.14 -7.33 -3.27 5.41 3.31
Nucleus 5.99 -9.14 -4.11 -43.07 25.35 5.81 -59.94 -13.76 -15.25 8.97 7.88 -103.56* -46.00 -51.15 22.92
Peroxisomes -7.32 2.01 1.70 9.41 -2.03 -6.14 10.82 11.20 12.37 0.68 -8.67 11.28 10.38 14.87 -1.69
Vacuole -15.86 -1.63 -13.23 1.84 -13.42 -15.03 0.48 -7.62 -4.18 -7.58 -17.99 7.20 -10.52 1.54 -13.41
Vacuole Periphery 0.17 1.90 1.27 3.50 -2.29 -8.84 8.73 0.14 6.35 -1.23 -9.84 9.16 -0.04 7.49 -2.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcriptional repressor; binds promoter sequences of cyclin genes, CYS3, and SMF2; not expressed during log phase of growth, but induced by stress or starvation during mitosis, and late in meiosis; represses 15% of all yeast genes as cells transition to quiescence; important for maintaining G1 arrest and for longevity of quiescent cells; member of Swi4p/Mbp1p family; phosphorylated by Cdc28p; relative distribution to nucleus increases upon DNA replication stress
Localization
Cell Percentages cytoplasm (10%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Xbp1

Xbp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Xbp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available