Standard name
Human Ortholog
Description Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0.05 0 0 0.05 0 0 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.11 0.13 0.09 0.07 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.14 0.28 0.38 0.17 0.41 0.36 0.42 0.52 0.49 0.43 0.54 0.05 0.05 0.2 0.08 0 0.15 0 0 0 0 0 0
Nucleus 0.87 0.84 0.83 0.88 0.84 0.74 0.75 0.71 0.65 0.63 0.63 0.63 0.85 0.83 0.77 0.88 0.84 0.83 0.73 0.74 0.71 0.79 0.72 0.61
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.18 0.22 0.16 0.13 0.16 0.24 0.25 0.25 0.29 0.33 0.35 0.38 0.14 0.11 0.17 0.05 0.05 0.05 0.21 0.13 0.15 0.14 0.18 0.28
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud 0 0 1 1 0 4 4 4 7 4 3 3 0 0 1 0 0 0 1 3 3 2 2 2
Bud Neck 0 0 1 0 1 0 0 3 0 1 0 0 0 1 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 3 7 1 17 19 16 19 19 11 20 0 1 3 0 0 0 – – – – – –
Cell Periphery 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3 9 4 6 9 10 15 18 15 14 8 9 33 52 65 9 7 10 0 4 0 0 0 1
Endoplasmic Reticulum 1 2 2 0 0 0 0 0 0 0 0 0 0 3 1 2 2 1 0 0 2 0 0 1
Endosome 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 2 1 6 1 1 1 5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 2 4 0 1 1
Mitochondria 0 40 62 100 56 156 192 176 188 213 112 185 21 25 96 8 3 16 0 3 4 0 1 2
Nucleus 120 243 185 229 279 279 399 300 237 275 165 216 330 386 374 90 80 90 106 223 167 174 234 206
Nuclear Periphery 0 6 6 4 3 2 9 4 7 14 5 3 1 3 2 1 0 0 0 0 0 0 0 0
Nucleolus 25 63 35 34 52 92 130 107 105 147 92 132 54 53 84 5 5 5 30 39 34 30 57 93
Peroxisomes 0 0 0 0 0 0 1 0 0 0 0 0 1 2 1 0 0 0 0 0 0 0 0 0
SpindlePole 1 2 3 2 3 1 7 4 2 2 3 4 2 7 3 0 0 2 0 4 3 4 3 5
Vac/Vac Membrane 2 5 2 0 3 3 2 1 2 3 0 1 2 6 2 1 4 0 3 10 12 5 16 11
Unique Cell Count 138 288 224 260 333 376 529 423 365 439 260 343 387 466 484 102 95 109 147 303 237 222 324 337
Labelled Cell Count 153 371 304 384 407 564 778 633 582 692 399 573 445 539 632 117 105 126 147 303 237 222 324 337


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.9 5.6 4.8 4.6 4.8 4.4 4.3 4.2 4.1 4.1 4.0 3.7 5.8 5.6 5.0 8.2 8.4 8.1 6.0 5.9 6.6
Std Deviation (1e-4) 1.1 1.1 1.1 1.2 1.5 1.3 1.0 1.2 1.6 1.5 1.1 0.9 1.2 1.3 1.1 2.1 2.0 1.4 1.2 1.0 1.3
Intensity Change (Log2) – – – -0.07 0.01 -0.13 -0.18 -0.18 -0.24 -0.25 -0.27 -0.4 0.28 0.21 0.05 0.76 0.8 0.75 0.33 0.28 0.46

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.7 0.7 0.8 1.6 1.5 1.1 0.9 0.7 3.4 4.2 4.9 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -7.7 -8.3 -2.3 -4.0 -5.0 -2.6
Nucleus 1.7 0.4 -2.4 -2.2 -3.3 -4.6 -5.3 -4.7 -5.0 0.9 0.1 -1.6 1.3 0.4 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 -0.6 -1.6 0.6 -2.7 -2.6 -2.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.0137 2.3992 2.0529 1.9469 2.3982 2.3413 3.3942 3.0837 3.1722 2.8806 2.4392 2.8629 3.6907 3.9878 3.8639 3.5022 3.1034 3.8355
Actin 0.0421 0 0.0055 0 0.0268 0.0037 0.02 0 0.0217 0.0469 0.0005 0.0024 0.0001 0 0.0053 0 0.0001 0
Bud 0.0013 0.0001 0.0001 0 0.0006 0.0001 0.001 0.0001 0.0008 0 0.0001 0 0.0001 0 0 0.0001 0 0
Bud Neck 0.0057 0.0005 0.0004 0.0002 0.0014 0.0118 0.0039 0.0001 0.0012 0.0001 0.001 0.0006 0.0004 0.0001 0.0001 0.0001 0.0009 0.0011
Bud Periphery 0.0044 0.0001 0.0001 0.0001 0.0012 0.0002 0.0023 0.0001 0.0012 0 0.0001 0 0.0002 0 0 0.0001 0 0.0001
Bud Site 0.0054 0.0005 0.0004 0.0001 0.002 0.0015 0.0068 0.0006 0.0096 0.0001 0.0003 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0001
Cell Periphery 0.0012 0 0 0 0.0002 0.0001 0.0003 0 0.0024 0 0 0 0.0001 0 0 0 0 0
Cytoplasm 0.0049 0.0001 0.0095 0.0001 0.0008 0.0002 0.0134 0 0.0082 0 0.0011 0.0004 0.0004 0.0005 0.0001 0.0001 0.0001 0.0001
Cytoplasmic Foci 0.0098 0 0.0028 0 0.0083 0.0033 0.0191 0 0.0086 0.0018 0.0038 0.0014 0 0 0.0078 0 0 0
Eisosomes 0.0004 0 0.0001 0 0.0002 0.0001 0.0002 0 0.0006 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0049 0 0.0003 0 0.0023 0.0011 0.0024 0 0.0023 0 0.0003 0.0008 0.0004 0 0.0001 0 0 0
Endosome 0.0181 0.0001 0.0033 0.0001 0.0569 0.008 0.0171 0.0001 0.0152 0 0.0027 0.0043 0.0002 0.0002 0.0016 0 0 0
Golgi 0.0085 0 0.0034 0 0.0329 0.0058 0.0036 0 0.0037 0.0005 0.0006 0.001 0 0 0.0015 0 0 0
Lipid Particles 0.0117 0 0.0032 0 0.0408 0.0084 0.0091 0 0.0032 0.0007 0.008 0.0018 0 0 0.004 0 0 0
Mitochondria 0.0207 0.0002 0.0149 0.0002 0.0228 0.0028 0.0062 0.0003 0.0018 0.0001 0.0003 0.0002 0.0006 0.0003 0.001 0.0003 0.0001 0.0001
None 0.0025 0 0.003 0.0001 0.0009 0.0001 0.0148 0 0.0016 0 0.0005 0.0002 0.0001 0.0001 0.0003 0 0.0001 0.0001
Nuclear Periphery 0.0406 0.0082 0.002 0.0007 0.0097 0.0012 0.0245 0.0003 0.0049 0.0001 0.006 0.0011 0.002 0.0042 0.0003 0.002 0.0019 0.0003
Nucleolus 0.084 0.0682 0.047 0.0773 0.1211 0.1384 0.0731 0.0604 0.0348 0.0697 0.1184 0.09 0.0721 0.0457 0.0397 0.0373 0.1427 0.1136
Nucleus 0.6928 0.92 0.8804 0.9201 0.6492 0.7963 0.7436 0.9356 0.863 0.8668 0.8054 0.8898 0.9195 0.9176 0.9251 0.9551 0.842 0.8662
Peroxisomes 0.0065 0 0.0014 0 0.0037 0.0028 0.0098 0 0.0056 0.0121 0.0007 0.0003 0 0 0.0046 0 0 0
Punctate Nuclear 0.0119 0.0016 0.0205 0.0006 0.0106 0.0132 0.0233 0.002 0.0053 0.0008 0.0498 0.0052 0.0028 0.0295 0.0081 0.0043 0.0118 0.0183
Vacuole 0.0154 0.0002 0.0014 0.0002 0.0043 0.0004 0.0038 0.0001 0.003 0 0.0002 0.0001 0.0005 0.0012 0 0.0002 0 0.0001
Vacuole Periphery 0.0076 0.0001 0.0003 0.0001 0.0034 0.0004 0.0014 0.0001 0.0012 0 0.0001 0.0001 0.0002 0.0003 0 0.0001 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.4024 18.5021 13.9545 14.2051 15.1772 11.5298 18.9375 17.2835 18.3138 17.5518
Translational Efficiency 1.1291 1.0216 1.0877 1.4995 1.152 1.2938 1.027 1.1003 1.0103 0.8403

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1550 1659 727 770 1850 2018 212 227 3400 3677 939 997

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 647.19 827.25 1107.21 785.14 737.00 826.74 1095.40 1024.68 696.06 826.97 1104.54 839.68
Standard Deviation 84.98 127.27 134.51 129.49 126.30 131.09 123.78 132.95 118.20 129.38 132.26 164.51
Intensity Change Log 2 — 0.354134 0.774668 0.278761 — 0.165769 0.571721 0.475437 — 0.256909 0.670172 0.386804

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000370 0.000635 0.001091 0.001184 0.000329 0.000513 0.001954 0.002047 0.000347 0.000568 0.001286 0.001381
Bud Neck 0.004227 0.012845 0.023950 0.017297 0.004700 0.008730 0.014089 0.047558 0.004485 0.010587 0.021723 0.024187
Bud Site 0.001562 0.001141 0.001692 0.005358 0.001327 0.001414 0.001604 0.009182 0.001434 0.001291 0.001672 0.006229
Cell Periphery 0.000195 0.000070 0.000037 0.000169 0.000097 0.000067 0.000043 0.000167 0.000142 0.000068 0.000038 0.000168
Cytoplasm 0.017217 0.003772 0.000403 0.010112 0.004947 0.002351 0.000314 0.009628 0.010540 0.002992 0.000383 0.010002
Cytoplasmic Foci 0.002739 0.001126 0.000030 0.003622 0.001063 0.000863 0.000051 0.012053 0.001827 0.000981 0.000035 0.005541
Eisosomes 0.000027 0.000033 0.000049 0.000032 0.000023 0.000031 0.000069 0.000046 0.000025 0.000032 0.000054 0.000035
Endoplasmic Reticulum 0.002671 0.002616 0.002392 0.005446 0.002023 0.002619 0.005239 0.005165 0.002319 0.002617 0.003035 0.005382
Endosome 0.000747 0.001087 0.000120 0.004838 0.000257 0.000601 0.000163 0.005203 0.000480 0.000821 0.000129 0.004921
Golgi 0.000632 0.000694 0.000224 0.004807 0.000266 0.000450 0.000241 0.010287 0.000433 0.000560 0.000228 0.006055
Lipid Particles 0.000714 0.000521 0.000060 0.000325 0.000408 0.000644 0.000175 0.000636 0.000547 0.000588 0.000086 0.000396
Mitochondria 0.001436 0.003116 0.001530 0.002681 0.002088 0.003378 0.001432 0.005271 0.001791 0.003260 0.001508 0.003271
Mitotic Spindle 0.000515 0.003175 0.002009 0.006815 0.001957 0.008628 0.000994 0.059248 0.001300 0.006168 0.001780 0.018753
None 0.033433 0.006485 0.001434 0.008552 0.014247 0.002821 0.001614 0.006557 0.022994 0.004474 0.001474 0.008098
Nuclear Periphery 0.000335 0.000702 0.000136 0.001189 0.000314 0.000533 0.000215 0.002170 0.000323 0.000609 0.000154 0.001413
Nuclear Periphery Foci 0.000937 0.001494 0.000108 0.001425 0.000887 0.000701 0.000267 0.001864 0.000910 0.001059 0.000144 0.001525
Nucleolus 0.091304 0.097255 0.105287 0.026292 0.092562 0.110747 0.073121 0.022070 0.091988 0.104660 0.098025 0.025331
Nucleus 0.838197 0.860318 0.856828 0.893762 0.871033 0.851183 0.894677 0.780365 0.856064 0.855305 0.865373 0.867944
Peroxisomes 0.000753 0.000911 0.001465 0.000875 0.000443 0.001112 0.002128 0.002089 0.000585 0.001021 0.001615 0.001152
Vacuole 0.001568 0.000793 0.000846 0.003741 0.000853 0.001445 0.001390 0.010118 0.001179 0.001151 0.000969 0.005193
Vacuole Periphery 0.000422 0.001211 0.000309 0.001477 0.000176 0.001168 0.000219 0.008279 0.000288 0.001188 0.000288 0.003026

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.68 -14.74 -7.68 -5.35 0.07 -4.52 -13.77 -8.81 -7.90 -0.34 -7.67 -20.16 -11.17 -8.88 -0.14
Bud Neck -10.78 -14.90 -11.46 -4.38 3.37 -6.44 -4.95 -8.89 -7.98 -5.99 -12.25 -15.45 -13.94 -9.55 -0.92
Bud Site 1.70 -2.07 -3.24 -3.74 -2.76 -0.17 -1.67 -4.34 -4.46 -3.94 0.53 -2.52 -4.54 -4.87 -3.90
Cell Periphery 5.94 7.71 1.29 -5.62 -8.04 1.36 2.61 -1.50 -3.13 -5.26 4.70 7.41 -0.78 -5.94 -9.21
Cytoplasm 6.67 8.89 2.66 -3.25 -5.26 1.97 6.24 0.16 -0.99 -2.55 6.60 10.45 0.92 -3.62 -5.75
Cytoplasmic Foci 2.68 4.15 0.73 -1.87 -3.38 0.78 3.15 -0.84 -1.05 -1.51 2.70 5.15 -0.51 -2.29 -3.65
Eisosomes -1.94 -9.37 -2.32 -0.81 6.15 -5.41 -12.60 -8.71 -6.80 1.34 -5.04 -16.38 -7.57 -4.47 5.73
Endoplasmic Reticulum 0.10 0.32 -7.49 -7.81 -7.78 -3.49 -9.77 -7.30 -6.27 -1.50 -2.38 -5.67 -10.78 -9.78 -7.54
Endosome -0.53 5.00 -2.98 -2.64 -3.73 -2.75 1.04 -2.00 -1.54 -2.05 -1.45 5.41 -3.59 -3.19 -4.08
Golgi 0.15 2.65 -2.03 -2.04 -2.35 -1.79 0.03 -1.10 -1.02 -1.10 -0.54 2.47 -2.43 -2.36 -2.60
Lipid Particles 0.87 3.64 1.51 0.54 -2.23 -0.90 1.73 0.43 1.32 -1.86 -0.04 4.25 1.17 1.10 -2.52
Mitochondria -1.89 -0.77 -2.72 0.44 -2.42 -1.57 0.62 -2.37 -1.22 -3.70 -2.43 0.49 -2.41 0.29 -3.85
Mitotic Spindle -3.19 -3.08 -4.39 -3.15 -2.13 -3.71 0.11 -3.05 -2.17 -3.07 -4.66 -2.59 -5.10 -3.15 -3.54
None 11.27 13.92 10.14 -1.39 -6.69 8.50 9.53 6.19 -2.86 -4.49 14.01 16.82 10.43 -3.49 -7.51
Nuclear Periphery -1.39 2.08 -3.64 -1.77 -4.21 -2.35 0.21 -4.18 -3.54 -4.21 -2.18 2.72 -4.96 -3.35 -5.45
Nuclear Periphery Foci -1.00 5.45 -0.84 -0.15 -2.38 0.96 2.53 0.51 -0.13 -1.14 -0.33 6.11 -0.87 -0.69 -2.52
Nucleolus -1.38 -4.97 18.02 20.20 17.41 -4.44 1.50 14.44 17.97 6.61 -4.24 -4.12 24.64 29.27 18.46
Nucleus -3.77 0.10 -6.12 -3.45 -5.98 3.46 -1.45 1.55 0.23 2.20 -0.22 1.55 -3.47 -3.40 -4.21
Peroxisomes -0.03 -3.44 0.62 0.65 3.12 -2.91 -5.70 -1.35 0.47 2.13 -2.41 -7.40 -0.62 1.02 3.74
Vacuole 1.95 1.20 -2.62 -3.56 -3.24 -1.15 -2.79 -2.97 -2.80 -2.65 0.23 -0.24 -4.19 -4.26 -4.15
Vacuole Periphery -1.81 1.64 -1.85 -0.07 -2.14 -2.95 -3.21 -1.24 -0.71 -1.20 -3.35 0.08 -2.27 -0.58 -2.27
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
Localization
Cell Percentages nucleus (94%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Hos4

Hos4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Hos4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available