Standard name
Human Ortholog
Description Putative mitochondrial porin (voltage-dependent anion channel); not required for mitochondrial membrane permeability or mitochondrial osmotic stability; POR2 has a paralog, POR1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.06
Bud 0 0 0.05 0 0 0 0 0.05 0.05 0 0.06 0.05 0 0 0 0 0.06 0.09 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0
Cytoplasm 0.3 0.1 0.06 0.06 0 0.07 0.07 0.1 0.15 0.16 0.15 0.09 0.13 0.25 0.39 0.17 0.23 0.17 0.05 0 0 0 0 0
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 0 0 0 0 0 0.07 0.05 0.05 0 0 0 0 0 0 0 0 0
Endosome 0 0.09 0.1 0.1 0.12 0 0 0 0.05 0 0 0 0.13 0.19 0.18 0.15 0.21 0.1 0.09 0.11 0.11 0.1 0.08 0.08
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0.05 0 0 0 0 0 0
Mitochondria 0.77 0.68 0.82 0.84 0.82 0.94 0.92 0.83 0.81 0.81 0.87 0.95 0.41 0.27 0.11 0.21 0.14 0.18 0.62 0.67 0.69 0.65 0.65 0.58
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.07 0.14 0.07 0 0 0 0 0 0 0 0.07 0 0 0 0.17 0 0 0 0.06 0.05 0.05 0.05
SpindlePole 0 0 0.05 0.06 0.07 0 0.05 0.11 0.05 0.08 0.05 0 0.07 0.05 0.07 0.28 0.14 0.19 0 0 0 0 0 0
Vac/Vac Membrane 0 0.18 0.07 0.05 0.09 0 0 0 0.05 0 0 0 0.2 0.24 0.2 0.12 0.12 0.19 0 0 0 0.06 0.08 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 2 1 0 0 1 0 0 0 0 0 0 14 4 5 3 3 5 2 3 3 2 9 26
Bud 1 2 9 3 8 6 18 20 15 11 19 21 5 5 2 4 9 11 0 1 0 2 3 9
Bud Neck 0 0 0 0 0 0 1 2 0 1 0 0 2 1 0 0 2 0 1 1 0 2 4 12
Bud Site 1 1 0 0 2 3 6 9 1 7 10 3 1 0 1 3 1 2 – – – – – –
Cell Periphery 0 5 2 5 2 0 0 1 4 0 1 2 6 3 12 5 5 8 0 0 0 0 0 2
Cytoplasm 18 13 10 10 13 17 29 43 45 67 46 37 33 66 115 19 32 21 4 5 0 1 3 5
Endoplasmic Reticulum 2 6 4 0 1 11 0 3 3 5 0 10 17 12 15 3 6 5 1 0 0 1 1 5
Endosome 0 12 17 17 42 0 1 16 15 4 4 0 35 49 54 17 30 13 7 18 21 30 34 36
Golgi 0 3 1 1 0 0 0 0 0 0 0 1 10 17 4 2 2 6 0 4 2 11 15 20
Mitochondria 46 91 143 140 289 236 374 353 241 338 271 406 106 70 32 24 20 22 50 111 136 195 273 271
Nucleus 0 0 0 2 4 8 13 10 2 4 4 2 7 5 1 5 4 5 0 1 0 1 3 1
Nuclear Periphery 0 0 0 0 1 3 1 2 0 1 1 3 0 0 0 0 1 2 1 1 1 0 1 3
Nucleolus 0 0 1 1 4 1 10 5 1 5 1 2 0 0 0 1 3 1 0 1 1 4 2 3
Peroxisomes 0 3 12 23 23 1 4 12 6 8 5 3 17 11 8 0 24 1 3 4 12 13 19 23
SpindlePole 2 5 9 10 23 8 20 45 14 33 17 11 17 14 21 32 20 24 2 2 6 6 6 6
Vac/Vac Membrane 0 24 13 8 32 5 7 8 15 10 5 7 52 62 58 14 17 23 1 5 5 18 33 32
Unique Cell Count 60 133 175 167 352 252 408 425 297 419 313 427 261 261 297 115 140 124 82 166 198 301 418 469
Labelled Cell Count 71 167 222 220 444 300 484 529 362 494 384 508 322 319 328 132 179 149 82 166 198 301 418 469


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 5.2 4.3 4.5 4.2 3.5 3.0 3.1 3.2 2.7 2.9 2.8 6.0 5.8 5.7 5.1 5.4 5.4 6.4 6.3 6.6
Std Deviation (1e-4) 2.2 1.2 1.0 1.3 1.4 1.0 1.3 0.9 1.1 0.5 1.0 0.7 0.9 0.9 0.8 1.1 1.1 1.0 1.2 1.3 1.5
Intensity Change (Log2) – – – 0.05 -0.04 -0.28 -0.5 -0.46 -0.44 -0.64 -0.57 -0.6 0.48 0.43 0.42 0.25 0.34 0.33 0.58 0.56 0.61

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 2.7 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 -1.9 -1.9 0 -0.7 0.5 1.3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 1.8 0 0 0
Cytoplasm 0.1 -1.1 0.4 0.6 1.7 3.1 3.4 3.0 1.2 2.4 5.3 7.8 3.0 4.4 3.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 2.0 1.3 1.5 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 1.2 2.6 2.5 1.3 2.9 0.2
Golgi 0 0 0 0 0 0 0 0 0 0 3.1 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 -8.5 -11.2 -15.4 -10.3 -11.9 -11.0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 -0.1 -1.2 -2.2 0 2.9 -2.5
SpindlePole 0 0 0 0 0 0 0 0 0 0.6 0.1 0.8 5.4 2.8 3.9
Vacuole -1.0 0.6 -2.8 -3.5 -3.4 -1.1 -2.9 -3.3 -3.6 3.6 4.4 3.6 1.4 1.4 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.9848 1.9281 1.8656 1.8899 1.1462 1.7816 3.2457 3.4403 3.1854 2.9718 2.9796 3.2996 0.5734 0.8092 0.6035 0.7734 0.547 0.6515
Actin 0.0028 0.0036 0.0033 0.0022 0.0065 0.0024 0.0107 0.006 0.0068 0.013 0.0197 0.0077 0.0142 0.004 0.0115 0.0051 0.0072 0.0042
Bud 0.0027 0.0022 0.0018 0.0056 0.0009 0.0003 0.0004 0.0011 0.0013 0.0008 0.0015 0.0003 0.0004 0.0011 0.0012 0.0008 0.0007 0.0003
Bud Neck 0.0005 0.0013 0.0007 0.0006 0.0004 0.0005 0.0016 0.0006 0.0008 0.0021 0.0064 0.0023 0.0023 0.0004 0.0009 0.0005 0.0004 0.0007
Bud Periphery 0.0014 0.0039 0.005 0.0083 0.0037 0.0008 0.0009 0.0016 0.0023 0.0022 0.0077 0.0007 0.0008 0.0018 0.0029 0.0017 0.0016 0.001
Bud Site 0.0035 0.0166 0.0044 0.002 0.0008 0.0005 0.0045 0.0111 0.0079 0.0025 0.002 0.0004 0.0035 0.0062 0.0079 0.0005 0.0008 0.0005
Cell Periphery 0.0009 0.0008 0.0004 0.0003 0.0003 0.0003 0.002 0.0005 0.0007 0.0004 0.0016 0.0002 0.0006 0.0005 0.0008 0.0002 0.0002 0.0003
Cytoplasm 0.0057 0.004 0.0029 0.0023 0.002 0.0008 0.0015 0.0045 0.0019 0.0012 0.0224 0.0053 0.0023 0.0062 0.0019 0.0156 0.0042 0.0019
Cytoplasmic Foci 0.0315 0.0467 0.0322 0.0496 0.0287 0.0211 0.033 0.0371 0.0281 0.0238 0.0256 0.0244 0.0289 0.0318 0.0371 0.0171 0.0277 0.025
Eisosomes 0.0004 0.0003 0.0003 0.0003 0.0001 0.0001 0.0013 0.0002 0.0004 0.0005 0.002 0.0002 0.0007 0.0002 0.0002 0.0005 0.0002 0.0002
Endoplasmic Reticulum 0.001 0.002 0.0006 0.0006 0.0024 0.0008 0.0012 0.0008 0.0006 0.0002 0.0004 0.0003 0.0019 0.0007 0.0005 0.0008 0.0006 0.0005
Endosome 0.1003 0.1082 0.0679 0.0799 0.0659 0.0516 0.0655 0.0835 0.0418 0.0385 0.0917 0.04 0.0988 0.0789 0.0733 0.086 0.0603 0.0618
Golgi 0.0757 0.0616 0.0444 0.0412 0.0742 0.0494 0.0517 0.0529 0.0371 0.0354 0.0961 0.0498 0.0602 0.0745 0.0575 0.0302 0.0662 0.042
Lipid Particles 0.0586 0.0404 0.025 0.0072 0.0115 0.0531 0.0527 0.0188 0.0259 0.0073 0.0105 0.0276 0.0986 0.0411 0.0462 0.0142 0.0162 0.0261
Mitochondria 0.6212 0.5907 0.7129 0.7499 0.7224 0.7322 0.6828 0.6739 0.7506 0.7988 0.6652 0.7677 0.5856 0.6726 0.6704 0.7527 0.6854 0.7411
None 0.0081 0.0123 0.0218 0.0035 0.0011 0.0016 0.0034 0.0033 0.0107 0.0006 0.0055 0.0044 0.0082 0.0036 0.0012 0.0027 0.0041 0.0069
Nuclear Periphery 0.0035 0.0058 0.0006 0.0021 0.0121 0.0024 0.0021 0.0003 0.0004 0.0001 0.0001 0.0002 0.0068 0.0009 0.0023 0.0009 0.0016 0.0003
Nucleolus 0.0013 0.0027 0.0008 0.0013 0.0002 0.0016 0.0019 0.0008 0.0006 0.0003 0.0002 0.0002 0.0021 0.001 0.0013 0.0003 0.0003 0.0004
Nucleus 0.0019 0.0018 0.0005 0.0017 0.0006 0.0005 0.0006 0.0006 0.0004 0.0002 0.0003 0.0002 0.0013 0.0013 0.0004 0.0008 0.0012 0.0003
Peroxisomes 0.0577 0.0719 0.064 0.0273 0.0606 0.072 0.0656 0.093 0.0756 0.0675 0.0365 0.0638 0.0523 0.0588 0.0714 0.0539 0.0955 0.0756
Punctate Nuclear 0.0021 0.0008 0.0005 0.0012 0.0007 0.0004 0.0013 0.0003 0.0003 0.0001 0.0001 0.0002 0.0024 0.0003 0.0006 0.0003 0.0191 0.0003
Vacuole 0.0113 0.0157 0.0056 0.007 0.0024 0.004 0.0105 0.0063 0.0032 0.0024 0.0025 0.0023 0.0181 0.0084 0.0056 0.0093 0.0033 0.0058
Vacuole Periphery 0.0078 0.0069 0.0045 0.0059 0.0026 0.0037 0.0045 0.0027 0.0027 0.0022 0.0021 0.0019 0.0101 0.0057 0.0047 0.0059 0.0033 0.0049

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 35.215 24.4845 18.1686 29.2941 29.593 26.0708 22.6932 35.4068 30.5265 30.2327
Translational Efficiency 0.8757 1.0606 1.5153 0.8693 1.0828 1.1539 0.9657 0.8833 0.8845 1.0167

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1520 1144 171 1577 1555 1911 102 1664 3075 3055 273 3241

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 646.87 755.96 966.33 889.19 682.50 722.18 1041.40 888.58 664.89 734.83 994.38 888.88
Standard Deviation 80.57 102.96 118.22 127.24 86.05 93.41 122.29 120.81 85.27 98.46 125.14 123.98
Intensity Change Log 2 — 0.224834 0.579040 0.459016 — 0.081529 0.609623 0.380673 — 0.153040 0.594823 0.419326

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000340 0.001447 0.004272 0.005081 0.000449 0.001025 0.006344 0.004286 0.000395 0.001183 0.005046 0.004673
Bud Neck 0.019489 0.008403 0.013152 0.021470 0.015386 0.007813 0.012253 0.029025 0.017415 0.008034 0.012816 0.025349
Bud Site 0.011693 0.016721 0.026272 0.088569 0.019029 0.011391 0.065946 0.064909 0.015403 0.013387 0.041095 0.076422
Cell Periphery 0.000494 0.000541 0.000321 0.000189 0.000438 0.000397 0.000360 0.000276 0.000466 0.000451 0.000336 0.000233
Cytoplasm 0.025725 0.007613 0.008075 0.058431 0.011796 0.006168 0.011109 0.056632 0.018681 0.006709 0.009209 0.057507
Cytoplasmic Foci 0.110562 0.071440 0.099802 0.121610 0.060818 0.055332 0.078403 0.115684 0.085407 0.061364 0.091807 0.118567
Eisosomes 0.000158 0.000136 0.000106 0.000097 0.000089 0.000103 0.000123 0.000132 0.000123 0.000115 0.000112 0.000115
Endoplasmic Reticulum 0.001353 0.000424 0.003415 0.001743 0.000532 0.000231 0.001745 0.001634 0.000938 0.000303 0.002791 0.001687
Endosome 0.088314 0.101031 0.171719 0.092059 0.100406 0.083201 0.108472 0.125686 0.094428 0.089878 0.148088 0.109324
Golgi 0.084883 0.130270 0.098530 0.080266 0.096713 0.141606 0.080159 0.071015 0.090865 0.137361 0.091666 0.075517
Lipid Particles 0.015094 0.004745 0.004134 0.002252 0.006337 0.003308 0.003029 0.006587 0.010666 0.003846 0.003721 0.004478
Mitochondria 0.540539 0.542333 0.213323 0.183316 0.589901 0.610798 0.281325 0.223481 0.565501 0.585160 0.238731 0.203938
Mitotic Spindle 0.006405 0.017954 0.142026 0.144607 0.009775 0.008817 0.147213 0.083103 0.008109 0.012238 0.143964 0.113030
None 0.001247 0.000434 0.000630 0.000342 0.000684 0.000332 0.000267 0.000937 0.000962 0.000370 0.000495 0.000648
Nuclear Periphery 0.000537 0.000200 0.001089 0.000791 0.000369 0.000048 0.000663 0.000947 0.000452 0.000105 0.000930 0.000871
Nuclear Periphery Foci 0.000430 0.000398 0.003280 0.001068 0.000283 0.000112 0.000846 0.001138 0.000356 0.000219 0.002371 0.001104
Nucleolus 0.002011 0.001430 0.005264 0.000964 0.001558 0.000750 0.001901 0.002472 0.001782 0.001005 0.004007 0.001738
Nucleus 0.008611 0.002476 0.013341 0.009047 0.002235 0.001133 0.005376 0.013968 0.005387 0.001636 0.010365 0.011573
Peroxisomes 0.033287 0.067787 0.062675 0.060957 0.029557 0.044267 0.140474 0.063924 0.031401 0.053074 0.091743 0.062480
Vacuole 0.027206 0.011972 0.084423 0.108942 0.025439 0.012531 0.040313 0.118933 0.026312 0.012321 0.067942 0.114071
Vacuole Periphery 0.021622 0.012245 0.044149 0.018202 0.028207 0.010636 0.013679 0.015230 0.024952 0.011238 0.032765 0.016676

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.45 -3.58 -8.40 -5.86 -0.38 -3.16 -3.79 -6.34 -5.24 1.31 -5.47 -5.15 -10.31 -8.00 0.61
Bud Neck 5.49 2.19 -1.44 -8.28 -3.61 3.75 1.11 -5.55 -10.14 -5.94 6.47 2.22 -5.10 -12.93 -6.64
Bud Site -2.45 -4.01 -19.24 -16.61 -11.14 3.78 -4.28 -12.31 -15.69 0.20 1.47 -5.35 -22.29 -23.30 -6.08
Cell Periphery -0.27 1.07 2.30 3.22 1.79 0.51 1.22 3.35 1.87 1.50 0.15 1.46 3.33 3.77 1.99
Cytoplasm 7.95 6.08 -10.38 -17.18 -15.18 3.81 -0.17 -13.90 -16.44 -9.91 8.91 3.94 -17.04 -23.90 -18.17
Cytoplasmic Foci 7.96 1.15 -1.57 -9.95 -2.01 1.74 -1.80 -13.01 -15.64 -4.20 8.34 -0.81 -9.39 -18.75 -3.78
Eisosomes 0.88 2.15 3.02 2.51 1.11 -2.05 -2.62 -5.92 -3.42 -0.68 0.64 0.67 0.79 0.10 -0.02
Endoplasmic Reticulum 3.31 -2.21 -1.63 -7.26 1.73 3.77 -3.18 -6.12 -8.38 0.49 4.43 -3.06 -4.42 -11.24 1.84
Endosome -2.24 -5.87 0.28 2.64 6.03 3.48 -0.62 -3.81 -7.87 -1.14 1.26 -5.25 -2.81 -4.24 4.23
Golgi -7.46 -0.95 2.46 9.44 1.92 -7.82 1.78 5.99 14.30 1.05 -11.17 0.13 6.02 16.97 2.28
Lipid Particles 6.06 6.24 8.18 2.50 2.05 2.42 2.11 -0.24 -3.24 -2.62 6.44 5.97 5.92 -1.26 -0.99
Mitochondria -0.18 14.28 34.03 30.35 1.89 -1.84 9.52 33.77 38.17 1.88 -2.30 17.39 47.73 49.98 2.32
Mitotic Spindle -6.13 -8.20 -22.75 -20.11 0.00 0.82 -6.46 -16.30 -16.68 2.95 -4.20 -10.42 -27.70 -26.34 2.37
None 4.75 1.16 5.36 0.84 1.04 2.68 3.59 -1.19 -3.01 -3.52 5.36 1.48 2.37 -2.56 -0.27
Nuclear Periphery 1.96 -2.20 -1.56 -3.25 0.71 1.46 -1.12 -2.20 -5.41 -0.43 2.56 -2.40 -2.70 -6.31 0.23
Nuclear Periphery Foci 0.17 -2.83 -3.94 -3.36 2.14 2.36 -2.73 -4.61 -5.80 -0.80 1.57 -3.17 -6.05 -6.94 1.98
Nucleolus 1.13 -1.36 1.96 0.22 1.63 1.79 -0.22 -2.09 -4.00 -0.69 2.36 -1.40 -0.85 -3.24 1.22
Nucleus 4.08 -1.24 -2.05 -6.28 0.57 1.96 -1.60 -9.47 -10.45 -2.83 4.93 -1.89 -7.49 -12.15 -0.47
Peroxisomes -7.37 -3.00 -6.59 1.75 0.52 -4.33 -5.24 -8.64 -4.38 3.64 -7.90 -5.88 -10.78 -2.34 3.01
Vacuole 7.67 -6.57 -20.37 -24.31 -4.89 7.27 -2.15 -20.67 -23.69 -6.66 10.39 -6.50 -29.01 -33.83 -7.87
Vacuole Periphery 5.70 -3.60 3.05 -2.73 4.41 10.11 5.21 7.50 -3.72 -0.45 11.82 -1.80 7.69 -4.75 4.17
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative mitochondrial porin (voltage-dependent anion channel); not required for mitochondrial membrane permeability or mitochondrial osmotic stability; POR2 has a paralog, POR1, that arose from the whole genome duplication
Localization
Cell Percentages mitochondrion (94%)
Cell Cycle Regulation No
Subcompartmental Group mito-2

Por2

Por2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Por2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available