Standard name
Human Ortholog
Description Transcription factor, allelic differences between S288C and Sigma1278b; mediates fermentation stress tolerance by modulating cell wall integrity; overexpression suppresses heat shock sensitivity of wild-type RAS2 overexpression and also suppresses cell lysis defect of mpk1 mutation; allele from S288c can confer fMAPK pathway independent transcription of FLO11; S288C and Sigma1278b alleles differ in number of tandem repeats within ORF
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0.07 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.65 0.56 0.83 0.61 0.69 0.42 0.18 0.25 0.3 0.2 0.22 0.25 0.83 0.77 0.8 0.89 0.93 0.85 0.45 0.42 0.43 0.63 0.64 0.66
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0.08 0 0 0 0 0 0
Endosome 0 0 0 0.05 0.06 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0.05 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.32 0.19 0.1 0.44 0.26 0.66 0.83 0.75 0.7 0.79 0.83 0.83 0 0 0 0.06 0 0.07 0.14 0.08 0.24 0.07 0.07 0.08
Nucleus 0 0.07 0 0.05 0 0.05 0.11 0.13 0.15 0.14 0.14 0.09 0.05 0.06 0.07 0 0 0 0.06 0.16 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0.07 0.05 0.05 0.06
Vac/Vac Membrane 0.11 0.25 0.07 0.05 0.08 0.11 0.1 0 0 0.06 0 0 0.09 0.16 0.12 0 0.05 0.07 0.15 0.18 0.08 0.12 0.12 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 3 2 1 2 1 6
Bud 2 1 0 0 0 1 12 4 7 8 10 14 1 0 0 0 0 2 2 3 1 1 6 5
Bud Neck 0 0 0 0 0 0 0 0 0 1 0 0 2 5 3 1 1 2 0 1 0 3 2 6
Bud Site 0 0 1 0 0 0 3 4 5 6 6 10 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 1 1 1 0 0 0 1 1 3
Cytoplasm 183 63 71 37 94 51 31 56 61 40 40 60 231 297 339 174 166 124 158 65 49 163 233 300
Endoplasmic Reticulum 2 4 3 0 1 0 1 1 0 0 0 0 2 3 1 13 11 11 5 0 4 1 1 2
Endosome 1 2 2 3 8 0 0 2 0 0 0 0 6 18 16 1 1 5 10 4 5 2 5 9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 1 0 0 0 0 0
Mitochondria 91 21 9 27 36 81 144 167 141 154 151 196 3 2 4 12 5 10 47 12 28 18 25 36
Nucleus 8 8 1 3 3 6 20 29 31 28 25 22 14 23 30 3 3 1 21 24 0 8 13 9
Nuclear Periphery 0 1 0 0 0 1 1 2 0 1 0 4 0 0 0 0 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 0 1 1 2 4 2 2 3 3 0 0 0 0 0 0 2 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 0 0 2 0 3 1 2 2 2 5 5 3 0 2 21 4 7 12 17 25
Vac/Vac Membrane 32 28 6 3 11 13 17 9 9 12 4 4 26 64 51 6 9 10 52 27 9 32 45 35
Unique Cell Count 282 113 86 61 136 122 174 223 202 196 182 237 278 388 423 196 179 146 349 155 116 260 365 456
Labelled Cell Count 320 128 95 74 155 154 234 278 259 253 241 315 287 417 452 215 197 171 349 155 116 260 365 456


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.3 4.5 4.1 3.7 4.2 3.2 3.4 3.2 4.6 3.1 2.7 2.7 5.2 5.2 5.1 5.0 5.1 5.0 5.3 5.5 5.7
Std Deviation (1e-4) 0.4 1.2 1.1 1.4 2.3 1.2 1.0 1.5 10.0 1.1 0.8 0.8 1.1 1.0 1.1 1.3 1.7 1.2 1.1 1.2 1.2
Intensity Change (Log2) – – – -0.12 0.04 -0.36 -0.28 -0.33 0.16 -0.42 -0.62 -0.62 0.35 0.36 0.32 0.29 0.33 0.28 0.37 0.43 0.48


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – 0
Bud Neck – – – – – – – – – – – – – – 0
Bud Site – – – – – – – – – – – – – – 0
Cell Periphery – – – – – – – – – – – – – – 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – 0
Endosome – – – – – – – – – – – – – – 0
Golgi – – – – – – – – – – – – – – 0
Mitochondria – – – – – – – – – – – – – – 0
Nuclear Periphery – – – – – – – – – – – – – – 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – 0
Peroxisomes – – – – – – – – – – – – – – 0
SpindlePole – – – – – – – – – – – – – – 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – 0
Cytoplasm – – – – – – – – – – – – – – 0
Nucleus – – – – – – – – – – – – – – 0
Vacuole – – – – – – – – – – – – – – 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.6164 1.7967 1.4809 1.7787 1.6167 1.8494 0.9567 0.253 0.1308 0.1542 0.6119 0.1156 -0.4481 -0.3194 -0.4985 -0.4682 -0.3393 -0.326
Actin 0.0095 0.001 0.0231 0.0153 0.0464 0.0024 0.0215 0.0045 0.0204 0.0915 0.0487 0.0015 0.0223 0.0002 0.0023 0.0005 0.0024 0.002
Bud 0.0055 0.0011 0.0005 0.0006 0.0003 0.0001 0.0019 0.0011 0.001 0.0007 0.0013 0.0003 0.001 0.0002 0.0001 0.0001 0.0002 0.0027
Bud Neck 0.0032 0.0009 0.0024 0.0023 0.0016 0.0038 0.0029 0.0006 0.0006 0.0048 0.001 0.0033 0.0084 0.0013 0.0007 0.0006 0.0025 0.0097
Bud Periphery 0.0017 0.0019 0.0007 0.0014 0.0007 0.0002 0.0086 0.001 0.0014 0.0006 0.0015 0.0004 0.0011 0.0001 0.0001 0.0001 0.0002 0.0009
Bud Site 0.002 0.0011 0.0056 0.0019 0.0026 0.0003 0.0028 0.0035 0.007 0.0043 0.0037 0.0006 0.0055 0.0027 0.0004 0.0001 0.0005 0.0004
Cell Periphery 0.0001 0 0.0003 0.0002 0.0003 0 0.0006 0.0002 0.0001 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0 0 0.0001
Cytoplasm 0.0522 0.0894 0.0385 0.0524 0.0505 0.0446 0.1789 0.3702 0.2872 0.2344 0.1234 0.2904 0.1053 0.2052 0.1305 0.0859 0.1311 0.0983
Cytoplasmic Foci 0.0084 0.0034 0.0053 0.0042 0.0086 0.0019 0.0518 0.0133 0.0131 0.0155 0.0178 0.0103 0.0111 0.0041 0.0133 0.0039 0.0081 0.0085
Eisosomes 0.0003 0.0001 0.0003 0.0003 0.0008 0.0001 0.0002 0.0001 0.0001 0.0002 0.0002 0.0001 0.0002 0 0.0001 0.0001 0.0002 0.0001
Endoplasmic Reticulum 0.0029 0.003 0.0019 0.0024 0.0067 0.002 0.0056 0.0075 0.0072 0.0058 0.0145 0.0047 0.0055 0.0053 0.005 0.0074 0.0027 0.0026
Endosome 0.0144 0.0037 0.0079 0.0156 0.0259 0.0056 0.0352 0.0117 0.008 0.0178 0.0166 0.009 0.0134 0.0048 0.0084 0.0068 0.0127 0.009
Golgi 0.0041 0.0002 0.003 0.0063 0.0064 0.0012 0.0246 0.0032 0.002 0.0284 0.0178 0.0006 0.0028 0.0001 0.001 0.0001 0.003 0.0011
Lipid Particles 0.0091 0.0004 0.0072 0.0122 0.0094 0.0037 0.0337 0.0025 0.0073 0.0092 0.0062 0.0019 0.0108 0.0003 0.0032 0.0005 0.0181 0.0053
Mitochondria 0.0132 0.0011 0.0046 0.0061 0.0067 0.0052 0.0564 0.0026 0.0021 0.0122 0.0246 0.0208 0.0017 0.0005 0.0009 0.0008 0.0017 0.0013
None 0.099 0.1488 0.172 0.1517 0.0995 0.0975 0.2723 0.4269 0.3758 0.0978 0.3996 0.1487 0.116 0.1056 0.2133 0.2591 0.1471 0.1288
Nuclear Periphery 0.0335 0.0274 0.031 0.0145 0.055 0.0266 0.0304 0.0144 0.0176 0.0225 0.0459 0.0185 0.0244 0.0254 0.0296 0.0401 0.0527 0.0239
Nucleolus 0.013 0.0117 0.0172 0.0078 0.032 0.0205 0.0032 0.0031 0.0029 0.0055 0.0012 0.0042 0.008 0.0105 0.0077 0.0026 0.0069 0.0142
Nucleus 0.6397 0.6524 0.5883 0.6673 0.5703 0.7206 0.2171 0.1076 0.1993 0.4229 0.2289 0.4369 0.5987 0.5775 0.5276 0.489 0.4582 0.6187
Peroxisomes 0.0119 0.0022 0.0098 0.0052 0.0015 0.0009 0.0187 0.0009 0.0084 0.0105 0.0237 0.0011 0.0084 0.0001 0.0023 0.0003 0.0024 0.0043
Punctate Nuclear 0.0724 0.0475 0.0767 0.0297 0.0679 0.061 0.0177 0.019 0.0309 0.0084 0.0175 0.0414 0.0509 0.0519 0.0509 0.0973 0.1467 0.0658
Vacuole 0.0026 0.0022 0.0027 0.0016 0.004 0.0012 0.0109 0.0051 0.0068 0.006 0.0046 0.0043 0.0032 0.0037 0.0018 0.0036 0.0015 0.002
Vacuole Periphery 0.0012 0.0005 0.001 0.0009 0.0027 0.0006 0.0051 0.0011 0.0009 0.0008 0.0012 0.0009 0.001 0.0005 0.0006 0.0012 0.0011 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1.3522 8.8645 4.1859 15.55 7.0128 3.6039 4.4814 6.0493 10.0472 6.3743
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
318 255 42 1311 1700 1772 907 1320 2018 2027 949 2631

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 668.10 769.16 1023.64 904.91 649.75 704.90 891.10 921.24 652.64 712.98 896.97 913.10
Standard Deviation 74.90 83.58 129.09 141.61 81.21 80.51 145.01 127.93 80.53 83.66 146.89 135.17
Intensity Change Log 2 — 0.203220 0.615572 0.437710 — 0.117534 0.455703 0.503692 — 0.161609 0.538962 0.470619

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000056 0.000707 0.002552 0.001753 0.000064 0.000190 0.000371 0.001540 0.000063 0.000255 0.000468 0.001646
Bud Neck 0.012839 0.014180 0.005785 0.020335 0.004092 0.011203 0.007587 0.021770 0.005471 0.011578 0.007507 0.021055
Bud Site 0.001577 0.010102 0.003070 0.017445 0.001449 0.003961 0.004250 0.029763 0.001469 0.004734 0.004198 0.023625
Cell Periphery 0.000135 0.000184 0.000348 0.000217 0.000116 0.000166 0.000811 0.000228 0.000119 0.000169 0.000790 0.000222
Cytoplasm 0.355970* 0.287837* 0.041720 0.142083* 0.420078* 0.312944* 0.095729 0.183663* 0.409976* 0.309786* 0.093339 0.162944*
Cytoplasmic Foci 0.268517* 0.226339* 0.003394 0.006884 0.077525 0.115068 0.012448 0.013447 0.107622 0.129066 0.012048 0.010177
Eisosomes 0.000177 0.000148 0.000110 0.000049 0.000043 0.000069 0.000433 0.000045 0.000064 0.000079 0.000419 0.000047
Endoplasmic Reticulum 0.000580 0.002567 0.021338 0.016939 0.001032 0.001541 0.003046 0.007817 0.000960 0.001670 0.003855 0.012362
Endosome 0.007807 0.021272 0.004549 0.008414 0.002088 0.005467 0.001153 0.012617 0.002989 0.007456 0.001303 0.010522
Golgi 0.001391 0.007127 0.000283 0.006648 0.000373 0.002412 0.000430 0.007250 0.000533 0.003005 0.000423 0.006950
Lipid Particles 0.014010 0.014015 0.002835 0.002123 0.004269 0.010656 0.001799 0.001318 0.005804 0.011079 0.001845 0.001719
Mitochondria 0.006040 0.008388 0.001783 0.010722 0.002659 0.012629 0.000992 0.007013 0.003192 0.012095 0.001027 0.008861
Mitotic Spindle 0.001288 0.002051 0.002909 0.052577 0.001184 0.008003 0.002575 0.053031 0.001201 0.007254 0.002590 0.052805
None 0.003125 0.004277 0.003314 0.007971 0.018072 0.007204 0.037446 0.007478 0.015717 0.006836 0.035935 0.007724
Nuclear Periphery 0.000642 0.001590 0.002050 0.006144 0.000957 0.002349 0.000850 0.004446 0.000907 0.002254 0.000903 0.005292
Nuclear Periphery Foci 0.000315 0.001969 0.006279 0.005231 0.000927 0.000890 0.000647 0.002470 0.000830 0.001026 0.000897 0.003846
Nucleolus 0.001616 0.004118 0.018675 0.007386 0.003425 0.005389 0.010062 0.007350 0.003140 0.005229 0.010443 0.007368
Nucleus 0.283038* 0.322102* 0.845066* 0.631371* 0.452333* 0.474010* 0.811914* 0.562818* 0.425655* 0.454900* 0.813381* 0.596977*
Peroxisomes 0.007875 0.026249 0.001242 0.000671 0.001233 0.007784 0.000500 0.001364 0.002280 0.010107 0.000533 0.001018
Vacuole 0.032678 0.043239 0.032340 0.052384 0.007652 0.017191 0.006537 0.064045 0.011595 0.020468 0.007679 0.058235
Vacuole Periphery 0.000322 0.001539 0.000357 0.002655 0.000432 0.000872 0.000418 0.010527 0.000414 0.000956 0.000416 0.006605

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.67 -6.99 -10.31 -3.67 3.65 -5.41 -11.18 -8.73 -7.65 -4.39 -6.34 -12.33 -13.46 -10.97 -5.91
Bud Neck -0.42 1.22 -2.99 -3.34 -8.08 -6.19 -4.14 -9.73 -4.34 -5.64 -5.28 -2.84 -13.18 -6.81 -8.60
Bud Site -3.56 -3.35 -8.11 -0.76 -5.32 -3.07 -2.38 -6.81 -5.21 -4.70 -4.24 -2.49 -10.23 -6.44 -5.87
Cell Periphery -2.36 -3.33 -3.05 0.33 2.74 -1.01 -6.56 -2.75 0.23 6.08 -1.16 -6.66 -5.47 -0.02 6.06
Cytoplasm 3.33 16.46 16.87 11.12 -5.04 12.07 39.86 31.49 19.22 -8.32 12.30 41.82 39.72 25.56 -7.64
Cytoplasmic Foci 2.23 20.61 20.72 16.40 -0.38 -7.44 20.49 22.13 26.12 1.99 -4.13 25.81 28.06 30.62 3.25
Eisosomes 1.39 1.32 7.75 6.91 3.42 -7.77 -3.87 -7.99 0.98 3.57 -3.90 -3.64 -0.63 3.97 3.62
Endoplasmic Reticulum -4.32 -6.52 -22.45 -17.34 1.80 -2.49 -11.01 -22.37 -19.71 -11.88 -3.77 -12.14 -30.15 -26.76 -15.55
Endosome -3.32 0.90 2.19 4.49 0.67 -5.90 2.74 -4.16 0.18 -5.26 -6.11 4.15 -3.31 3.17 -6.50
Golgi -1.59 1.36 -0.11 1.60 -2.26 -4.27 0.02 -2.50 0.51 -2.41 -4.05 0.95 -2.73 1.29 -3.18
Lipid Particles -0.27 3.84 4.55 5.68 1.61 -7.98 4.95 6.95 12.28 -0.14 -6.44 6.35 7.62 13.36 -0.19
Mitochondria -0.56 1.32 0.23 1.05 -2.71 -6.17 3.71 -1.40 5.31 -4.00 -5.85 3.41 -1.46 4.90 -4.88
Mitotic Spindle -1.10 -1.22 -10.28 -9.96 -8.48 -4.49 -2.17 -9.34 -6.89 -8.36 -4.59 -2.30 -13.92 -10.86 -12.46
None -1.05 -0.42 -3.23 -2.19 -2.36 6.51 -3.41 7.85 1.27 6.91 6.18 -3.93 7.56 1.07 6.91
Nuclear Periphery -3.00 -3.70 -16.79 -12.15 -8.72 -6.83 -2.35 -15.07 -10.57 -13.81 -7.42 -3.25 -21.85 -15.81 -19.52
Nuclear Periphery Foci -4.56 -2.58 -8.43 -4.54 0.64 -0.36 -1.50 -5.06 -5.03 -3.12 -1.58 -2.23 -8.62 -8.06 -4.38
Nucleolus -2.92 -2.66 -6.55 -3.20 1.96 -3.66 -5.57 -3.57 -1.23 2.54 -4.29 -6.28 -6.04 -2.53 2.85
Nucleus -1.63 -14.93 -21.05 -14.82 5.38 -1.94 -33.78 -11.99 -9.96 18.82 -2.87 -38.15 -20.10 -16.21 20.80
Peroxisomes -3.51 4.64 5.74 5.24 2.70 -8.85 5.86 1.83 9.09 -0.93 -8.43 7.31 6.40 10.53 -0.44
Vacuole -1.43 -0.71 -11.21 -9.08 -3.63 -8.40 -1.49 -21.22 -19.33 -20.25 -6.48 0.22 -27.04 -24.40 -25.60
Vacuole Periphery -3.18 -1.81 -2.88 1.23 -2.18 -4.44 0.27 -3.18 -2.62 -3.14 -5.48 0.19 -3.74 -2.41 -3.40
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transcription factor, allelic differences between S288C and Sigma1278b; mediates fermentation stress tolerance by modulating cell wall integrity; overexpression suppresses heat shock sensitivity of wild-type RAS2 overexpression and also suppresses cell lysis defect of mpk1 mutation; allele from S288c can confer fMAPK pathway independent transcription of FLO11; S288C and Sigma1278b alleles differ in number of tandem repeats within ORF
Localization
Cell Percentages cytoplasm (19%), nucleus (18%), mixed (52%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rpi1

Rpi1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpi1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available