Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L16A; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16A has a paralog, RPL16B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.06 0.05 0.26 0.23 0.1 0.1 0.09 0.09 0.05 0.09 0 0.08 0.14 0.13 0.19 0.11 0.11 0.09 0.06 0 0.11 0.05 0.05 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.12 0.15 0 0 0 0.1 0.07 0.06 0.46 0.51 0.49 0.45 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.88 0.91 0.74 0.7 0.85 0.79 0.88 0.82 0.78 0.66 0.78 0.71 0.84 0.84 0.75 0.84 0.8 0.81 0.89 0.9 0.77 0.8 0.73 0.62
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0.06 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0.07 0.05 0.05 0 0 0 0 0 0.05 0 0 0.05 0.05 0.11 0.09 0 0.05 0 0.05 0.14 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0
Bud 0 0 0 0 1 0 0 0 2 2 2 1 0 0 0 1 0 0 0 2 1 1 3 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 2 1 4 5 8 7 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1 14 8 10 17 15 21 20 10 14 8 18 20 30 53 16 13 17 3 2 6 7 14 7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 3 0 0 1 0 0 1
Endosome 0 0 0 0 0 0 1 1 0 0 0 0 0 1 2 0 1 1 0 1 1 1 0 5
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1
Mitochondria 2 46 0 1 1 15 16 13 89 76 124 97 1 0 1 7 3 4 0 3 0 2 1 6
Nucleus 14 274 23 31 141 121 215 174 152 98 197 152 121 200 206 125 96 145 42 282 48 111 195 164
Nuclear Periphery 0 1 0 1 0 1 0 1 4 0 2 2 2 0 1 5 2 1 0 0 0 1 0 4
Nucleolus 0 2 0 0 2 5 3 4 11 7 13 9 0 3 1 1 0 0 0 0 0 2 5 9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 2 3 0 2 2 2 0 3 1 0 0 2 0 1 0 3 3 1
Vac/Vac Membrane 0 12 0 3 8 8 4 9 2 3 5 10 3 9 13 8 13 16 0 16 1 6 36 53
Unique Cell Count 16 301 31 44 166 153 244 211 195 149 251 214 144 239 274 149 120 179 48 313 63 140 267 266
Labelled Cell Count 17 350 32 46 170 166 264 226 274 207 361 298 147 246 279 167 128 189 48 313 63 140 267 266


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.9 5.7 8.2 7.0 7.3 5.6 5.5 5.8 4.5 4.1 4.3 4.4 7.1 7.0 6.8 6.6 7.8 8.9 7.8 8.2 7.8
Std Deviation (1e-4) 1.3 1.5 1.6 1.8 1.7 1.3 1.1 1.8 1.1 1.0 0.8 1.0 1.6 1.4 1.4 1.8 1.8 2.6 1.8 1.7 1.5
Intensity Change (Log2) – – – -0.23 -0.17 -0.56 -0.57 -0.51 -0.86 -1.01 -0.92 -0.9 -0.21 -0.23 -0.27 -0.33 -0.07 0.11 -0.08 -0.01 -0.08


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.3 0 0 0 0 0 0 0 0 0 0 -0.9 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus -0.4 1.5 0.6 2.1 1.1 0.5 -0.9 0.5 -0.4 1.3 1.3 0.1 1.3 0.7 0.9
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 91.1589 108.5362 104.1323 104.1411 103.2101 93.1533 81.5672 109.3743 98.7646 85.7965 75.6536 80.2624 87.6943 111.6192 102.1211 99.1069 90.37 79.977
Actin 0.0129 0.0007 0.0043 0.0005 0.0001 0.004 0.0127 0.0006 0.0092 0.0024 0.0187 0.0028 0.0018 0.0005 0.0041 0.0003 0.0001 0.0236
Bud 0.0021 0.0016 0.0049 0.0027 0.0008 0.0008 0.002 0.0006 0.0015 0.0035 0.0041 0.0054 0.0009 0.0007 0.0034 0.0015 0.0003 0.0008
Bud Neck 0.0008 0.0009 0.0015 0.0015 0.0007 0.0013 0.0008 0.0005 0.0007 0.0014 0.0019 0.0023 0.0008 0.0005 0.0007 0.0011 0.0003 0.0028
Bud Periphery 0.0024 0.0012 0.0038 0.001 0.0004 0.0025 0.0025 0.0005 0.0009 0.0025 0.007 0.003 0.0009 0.0004 0.0051 0.0007 0.0001 0.0005
Bud Site 0.001 0.0014 0.0012 0.0004 0.0001 0.0002 0.0016 0.0004 0.0009 0.0006 0.0008 0.0007 0.0011 0.0016 0.0023 0.0003 0.0001 0.0011
Cell Periphery 0.0232 0.0086 0.0153 0.0091 0.001 0.0059 0.0105 0.0054 0.0113 0.0133 0.0053 0.0034 0.018 0.0114 0.0063 0.0046 0.009 0.0013
Cytoplasm 0.5705 0.877 0.7221 0.6151 0.7084 0.6584 0.6308 0.9474 0.8533 0.5815 0.6101 0.6405 0.7367 0.9139 0.8254 0.661 0.671 0.801
Cytoplasmic Foci 0.0041 0.0021 0.0032 0.0028 0.0074 0.0101 0.0127 0.0012 0.0023 0.0044 0.0101 0.013 0.0066 0.0025 0.0027 0.0115 0.0221 0.0145
Eisosomes 0.0004 0 0.0002 0 0 0.0002 0.0004 0 0 0.0001 0.0002 0.0001 0.0001 0 0.0002 0.0001 0.0002 0.0004
Endoplasmic Reticulum 0.0803 0.0289 0.0447 0.004 0.0026 0.0979 0.0802 0.0131 0.0177 0.0294 0.0202 0.0559 0.0569 0.0073 0.0055 0.0019 0.0011 0.0083
Endosome 0.0185 0.0067 0.0128 0.0107 0.0657 0.0578 0.0126 0.003 0.0082 0.0198 0.0396 0.0433 0.0079 0.002 0.0048 0.0051 0.0103 0.0212
Golgi 0.0037 0.0009 0.0017 0.0003 0.0031 0.0067 0.0037 0.001 0.0016 0.0026 0.0089 0.0338 0.0016 0.0005 0.0006 0.0003 0.0004 0.0026
Lipid Particles 0.0017 0.0007 0.0013 0.0011 0.0005 0.004 0.0042 0.0004 0.0007 0.0024 0.0028 0.0011 0.0061 0.0011 0.0016 0.0042 0.0086 0.0027
Mitochondria 0.0118 0.001 0.005 0.0018 0.0006 0.0117 0.0162 0.0008 0.0024 0.0133 0.0481 0.0153 0.0028 0.0007 0.005 0.0032 0.0085 0.0012
None 0.0042 0.0002 0.0019 0.0011 0.0002 0.0309 0.0065 0.0002 0.0006 0.0019 0.0035 0.0031 0.0037 0.0002 0.002 0.0126 0.0074 0.0302
Nuclear Periphery 0.0552 0.0035 0.0112 0.0182 0.0032 0.0527 0.0397 0.0029 0.0162 0.0128 0.0482 0.0064 0.0299 0.0048 0.0094 0.0068 0.0061 0.0233
Nucleolus 0.0014 0.0001 0.0009 0.0034 0.0001 0.0004 0.0051 0.0001 0.0004 0.002 0.0155 0.0054 0.0057 0.0002 0.0006 0.0043 0.0773 0.0025
Nucleus 0.013 0.0019 0.005 0.0127 0.0014 0.0055 0.0162 0.0017 0.0051 0.0076 0.0144 0.0148 0.0117 0.0021 0.0054 0.0074 0.0109 0.0146
Peroxisomes 0.0003 0.0001 0.0002 0.0001 0.0001 0.0006 0.0015 0 0.0001 0.0003 0.0007 0.0005 0.01 0.0029 0.0004 0.0005 0.0007 0.0011
Punctate Nuclear 0.0014 0 0.0001 0.0002 0 0.0063 0.006 0 0.0002 0.0002 0.0014 0.0003 0.0018 0 0.0004 0.0012 0.0098 0.0313
Vacuole 0.1422 0.0514 0.1175 0.2417 0.1367 0.0191 0.1039 0.0169 0.054 0.22 0.0622 0.1034 0.0713 0.0414 0.0897 0.2154 0.0853 0.0121
Vacuole Periphery 0.049 0.0112 0.041 0.0715 0.067 0.0229 0.0301 0.0032 0.0126 0.0783 0.0763 0.0454 0.0239 0.0051 0.0242 0.0561 0.0705 0.0029

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1010.5346 1132.6886 1527.3016 1280.031 1304.2414 979.6483 1087.9142 1010.8115 1095.0923 1087.2114
Translational Efficiency 1.5026 1.5803 1.2797 1.6221 1.4529 1.6372 1.5377 1.4764 1.4218 1.5709

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2102 1114 2116 1488 1258 2915 1245 1544 3360 4029 3361 3032

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 5060.05 4927.20 7600.46 5606.20 4397.84 5302.92 6517.94 5732.60 4812.12 5199.04 7199.47 5670.57
Standard Deviation 998.59 1546.36 1296.15 2022.56 999.10 1189.06 1401.06 1944.02 1048.94 1308.57 1434.61 1983.96
Intensity Change Log 2 — -0.038384 0.586935 0.147872 — 0.269992 0.567621 0.382394 — 0.113233 0.577986 0.261678

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000044 0.000108 0.000065 0.000322 0.000053 0.000043 0.000122 0.000183 0.000047 0.000061 0.000086 0.000252
Bud Neck 0.000173 0.000602 0.000890 0.002817 0.000236 0.000164 0.002512 0.001698 0.000197 0.000285 0.001491 0.002247
Bud Site 0.001403 0.004170 0.001893 0.012796 0.002235 0.003485 0.004024 0.010887 0.001715 0.003674 0.002683 0.011824
Cell Periphery 0.022411 0.030016 0.017832 0.018652 0.030607 0.011510 0.015067 0.030098 0.025480 0.016627 0.016808 0.024481
Cytoplasm 0.628754* 0.540816* 0.552496* 0.651922* 0.499428* 0.739380* 0.551213* 0.699336* 0.580334* 0.684478* 0.552021* 0.676067*
Cytoplasmic Foci 0.012425 0.010161 0.004600 0.008275 0.009275 0.017330 0.005777 0.010660 0.011246 0.015348 0.005036 0.009490
Eisosomes 0.000002 0.000003 0.000002 0.000006 0.000002 0.000001 0.000003 0.000003 0.000002 0.000002 0.000002 0.000004
Endoplasmic Reticulum 0.004926 0.002686 0.001315 0.000576 0.003994 0.002909 0.000603 0.000379 0.004577 0.002847 0.001051 0.000476
Endosome 0.001050 0.001254 0.000593 0.001658 0.000984 0.000978 0.000886 0.000829 0.001025 0.001054 0.000701 0.001236
Golgi 0.069897 0.085701 0.032349 0.012678 0.082740 0.043392 0.027620 0.016730 0.074705 0.055090 0.030597 0.014741
Lipid Particles 0.024350 0.028454 0.013951 0.015577 0.019539 0.008620 0.016305 0.020578 0.022549 0.014104 0.014823 0.018124
Mitochondria 0.000207 0.000220 0.000216 0.000535 0.000304 0.000719 0.000184 0.000352 0.000243 0.000581 0.000204 0.000442
Mitotic Spindle 0.000661 0.000830 0.000755 0.006142 0.000745 0.000919 0.001748 0.004050 0.000693 0.000894 0.001123 0.005077
None 0.001107 0.003764 0.001071 0.003011 0.001492 0.001464 0.001200 0.002557 0.001251 0.002100 0.001119 0.002780
Nuclear Periphery 0.000668 0.000802 0.001263 0.000577 0.000710 0.000257 0.001184 0.000463 0.000684 0.000408 0.001234 0.000519
Nuclear Periphery Foci 0.014060 0.018366 0.012992 0.007610 0.013184 0.005676 0.014228 0.010239 0.013732 0.009184 0.013450 0.008949
Nucleolus 0.000056 0.000141 0.000102 0.000600 0.000097 0.000062 0.000149 0.000211 0.000071 0.000084 0.000119 0.000402
Nucleus 0.002099 0.007727 0.006344 0.029455 0.002225 0.001590 0.016014 0.017251 0.002146 0.003287 0.009926 0.023240
Peroxisomes 0.000064 0.000083 0.000024 0.000229 0.000061 0.000096 0.000030 0.000095 0.000063 0.000092 0.000026 0.000160
Vacuole 0.110383 0.149051 0.251912* 0.197957 0.143593 0.063859 0.283454* 0.150900 0.122817 0.087414 0.263596* 0.173994
Vacuole Periphery 0.105260* 0.115046* 0.099336 0.028605 0.188496* 0.097547 0.057677 0.022500 0.136424* 0.102385* 0.083904 0.025496

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.24 -5.36 -3.91 -2.91 -3.35 1.66 -6.93 -8.30 -9.02 -2.07 -3.32 -8.73 -6.04 -5.61 -4.18
Bud Neck -7.46 -6.36 -9.89 -8.84 -6.74 1.64 -10.64 -9.74 -9.97 1.18 -3.84 -11.97 -13.69 -13.29 -5.28
Bud Site -6.03 -4.03 -10.21 -7.11 -9.51 -4.06 -4.73 -9.17 -8.11 -5.80 -8.62 -5.97 -13.84 -11.16 -11.40
Cell Periphery -4.07 3.77 5.02 7.93 1.85 10.59 8.58 1.65 -8.23 -6.40 8.07 8.45 3.37 -3.50 -3.83
Cytoplasm 6.72 8.28 0.28 -6.26 -7.62 -21.34 -2.16 -13.50 6.80 -10.90 -13.17 5.14 -8.22 4.51 -13.39
Cytoplasmic Foci 1.91 9.19 -0.51 -1.93 -6.37 -8.42 2.06 -5.66 -1.34 -6.58 -5.22 8.88 -4.41 -0.99 -9.42
Eisosomes -4.86 -2.47 -2.92 -2.02 -2.62 4.41 -5.22 -6.50 -9.39 -0.00 0.44 -5.59 -4.22 -4.30 -2.83
Endoplasmic Reticulum 3.62 7.24 8.68 5.40 5.14 2.20 7.55 8.04 13.19 3.06 4.41 9.94 11.57 13.05 6.75
Endosome -2.27 7.49 -2.65 -1.76 -4.52 0.06 0.06 -0.63 -0.68 -0.51 -0.61 4.69 -2.58 -2.35 -4.55
Golgi -3.81 15.67 25.43 21.98 17.32* 11.98 18.34 22.10 15.14 6.73 8.58 23.53 33.05 26.03 16.85
Lipid Particles -1.76 7.32 5.85 6.15 -0.25 7.65 1.79 -1.04 -8.08 -2.76 7.35 7.02 3.43 -3.35 -2.74
Mitochondria -0.72 -1.67 -3.89 -3.61 -3.40 -4.84 1.52 -0.72 3.22 -1.77 -6.14 0.23 -3.47 1.50 -3.64
Mitotic Spindle -2.66 -2.85 -6.59 -6.47 -6.44 -1.30 -2.76 -4.72 -4.54 -3.38 -2.07 -3.38 -8.09 -7.83 -7.32
None -2.84 0.02 -4.27 0.68 -4.18 0.06 0.57 -1.99 -2.23 -2.75 -2.68 0.50 -4.64 -1.58 -5.00
Nuclear Periphery -2.03 -8.32 -2.10 -0.34 5.14 11.14 -6.44 1.24 -8.02 6.95 8.15 -10.50 -1.06 -6.89 8.71
Nuclear Periphery Foci -3.16 0.45 6.89 7.53 6.57 10.55 -1.47 1.10 -6.20 2.23 7.39 -0.50 5.18 -1.00 5.49
Nucleolus -7.64 -12.73 -3.94 -3.40 -3.60 3.47 -6.53 -5.78 -6.76 -3.06 -2.44 -11.82 -5.12 -4.93 -4.29
Nucleus -4.61 -9.46 -17.12 -13.39 -14.36 1.55 -11.89 -14.81 -15.49 -0.24 -2.97 -14.90 -22.11 -20.81 -12.64
Peroxisomes -0.66 5.17 -1.87 -1.53 -2.42 -2.79 2.36 -2.03 -0.13 -3.64 -2.58 5.33 -2.30 -1.49 -3.30
Vacuole -6.01 -22.58 -12.86 -6.47 6.89 15.37 -16.22 -1.95 -16.34 14.29 9.75 -27.66 -11.43 -19.61 15.12
Vacuole Periphery -1.70 2.09 24.77* 19.97 24.94* 15.18 22.88 30.22* 27.45* 12.33* 9.50 16.23 38.17 33.87* 27.88*
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ribosomal 60S subunit protein L16A; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16A has a paralog, RPL16B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-2

Rpl16a

Rpl16a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl16a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available