Standard name
Human Ortholog
Description Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.07 0 0 0 0 0 0.05 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0
Cytoplasm 0.1 0.12 0.09 0.09 0 0 0 0 0 0 0 0 0.15 0.13 0.1 0.09 0.19 0.22 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0 0 0
Endosome 0.1 0.08 0 0 0.05 0 0 0 0 0 0 0 0.12 0.11 0.16 0.18 0.11 0.15 0.09 0.09 0.08 0.08 0.09 0.09
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.13 0.17 0.1 0.08 0 0 0 0 0 0 0
Mitochondria 0.67 0.71 0.87 0.85 0.89 0.91 0.87 0.86 0.92 0.91 0.95 0.95 0.44 0.47 0.43 0.22 0.11 0.14 0.71 0.67 0.77 0.66 0.61 0.6
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0.07 0.07 0.06 0.05 0.06 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0.08 0.1 0.11 0.06 0.06 0.08 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.05 0.06 0 0.05 0 0 0 0 0 0 0 0 0.1 0.08 0.17 0.18 0.12 0.11 0 0 0 0.05 0.05 0
SpindlePole 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0 0.15 0.13 0.13 0 0 0 0 0 0
Vac/Vac Membrane 0.22 0.12 0 0 0.08 0.08 0.08 0.08 0.06 0.06 0.05 0 0.23 0.27 0.28 0.16 0.21 0.21 0.05 0.05 0 0.06 0.08 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 3 0 0 1 1 0 3 2 0 0 4 4 3 2 6 3 2 7 28 10 6 10 15
Bud 2 8 39 26 19 29 32 22 42 34 28 48 4 3 1 15 8 7 3 8 1 5 8 10
Bud Neck 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 2 1 0 1 6 1 4 8 8
Bud Site 1 2 2 3 6 17 6 5 11 6 9 12 0 0 0 1 5 1 – – – – – –
Cell Periphery 11 27 19 11 9 1 13 4 5 6 10 7 16 15 16 23 6 6 0 1 1 0 1 0
Cytoplasm 41 73 51 55 36 29 26 20 10 13 12 10 61 56 53 25 38 39 5 9 1 2 3 7
Endoplasmic Reticulum 9 13 6 3 6 6 2 4 1 3 4 7 3 5 4 11 16 11 3 7 3 4 3 4
Endosome 42 50 16 22 47 3 14 18 1 12 0 5 46 49 81 52 23 27 41 65 49 29 36 42
Golgi 5 11 1 2 1 0 1 4 1 1 4 5 29 56 84 28 17 4 16 30 14 13 15 18
Mitochondria 269 431 492 503 847 943 1103 998 825 887 855 1099 174 208 219 65 23 25 322 493 477 234 256 274
Nucleus 2 5 1 2 7 18 19 12 10 6 4 7 6 2 4 5 11 7 0 1 0 1 2 2
Nuclear Periphery 2 3 2 5 39 71 90 65 47 63 37 57 0 4 5 1 3 2 4 4 8 2 4 2
Nucleolus 2 2 2 1 37 87 123 124 57 58 70 85 1 0 4 2 1 0 1 1 1 0 4 1
Peroxisomes 21 37 21 28 13 9 13 17 5 11 3 10 41 37 86 52 24 19 12 16 24 18 21 18
SpindlePole 11 13 31 21 15 13 15 7 9 10 9 17 14 20 9 43 26 24 4 10 8 3 7 7
Vac/Vac Membrane 90 75 19 24 77 81 104 96 56 62 41 35 91 120 140 45 43 37 23 37 7 22 33 34
Unique Cell Count 401 609 568 594 957 1034 1263 1163 897 970 896 1161 395 443 509 289 204 178 457 732 624 354 423 456
Labelled Cell Count 510 753 704 706 1160 1309 1561 1399 1082 1172 1086 1408 490 578 708 376 248 211 457 732 624 354 423 456


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.2 5.2 4.1 4.3 5.1 5.7 6.5 7.1 8.2 8.4 9.6 10.2 6.6 7.0 7.8 6.3 6.2 6.0 6.9 6.8 7.0
Std Deviation (1e-4) 1.2 1.2 1.1 1.4 1.4 1.7 2.4 2.6 4.0 4.7 6.0 6.3 1.6 2.0 3.4 1.4 1.6 1.3 4.9 5.5 5.8
Intensity Change (Log2) – – – 0.09 0.32 0.49 0.68 0.8 1.01 1.05 1.24 1.33 0.7 0.78 0.93 0.64 0.6 0.55 0.75 0.75 0.79

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 -4.8 -3.9 -4.4 -5.3 -1.8 -3.0 -3.3 -2.4 -4.3 -4.9 -5.8 -1.0 -1.5 -1.4
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 2.3 0 0 1.7 0 0 0 0 0 0 0 0 0
Cell Periphery 0 -3.4 -5.6 -3.5 -5.1 -4.1 -4.1 -3.0 -4.4 0.6 0 -0.2 3.0 -0.3 0
Cytoplasm 0.2 -4.2 -5.4 -6.8 -7.2 -7.3 -7.2 -7.0 -8.6 3.1 1.9 0.8 -0.2 3.7 4.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 2.7 5.0 0
Endosome 0 2.0 -4.5 -2.7 -1.8 -4.7 -2.2 -5.1 -4.3 5.5 5.3 7.5 7.8 4.7 6.2
Golgi 0 0 0 0 0 0 0 0 0 6.3 8.5 9.9 7.3 0 0
Mitochondria 0 1.1 2.9 0.4 -0.5 3.3 3.0 6.1 5.8 -14.1 -13.6 -15.1 -18.6 -19.6 -18.3
Nucleus 0 0 2.8 2.5 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 4.3 6.0 6.1 5.3 5.1 5.8 4.4 4.9 0 0 0 0 0 0
Nucleolus 0 4.2 6.7 7.4 7.8 5.7 5.5 6.4 6.2 0 0 0 0 0 0
Peroxisomes 0 -3.0 -4.0 -3.9 -3.0 -4.4 -3.4 -4.9 -4.2 4.2 3.2 7.2 7.1 4.2 3.6
SpindlePole 0 -4.3 -4.9 -5.4 -6.5 -5.1 -5.2 -5.1 -4.7 -1.4 -0.7 -3.2 4.6 3.4 3.6
Vacuole 0.6 3.7 3.6 3.9 3.9 2.5 2.6 1.2 -0.4 9.4 10.9 11.2 6.4 8.0 7.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.3911 1.1335 1.3294 0.6168 1.4579 1.3723 4.5383 4.5686 4.3356 3.2569 4.0783 4.7638 1.498 1.544 1.3388 1.2203 0.8443 1.4456
Actin 0.0073 0.0153 0.0199 0.0071 0.0222 0.0111 0.0316 0.0076 0.0246 0.0072 0.0228 0.0097 0.0256 0.023 0.0099 0.0043 0.0275 0.0051
Bud 0.0033 0.0138 0.0102 0.009 0.0044 0.0032 0.0009 0.0027 0.007 0.0017 0.0011 0.0008 0.0016 0.0061 0.0039 0.0029 0.0005 0.0017
Bud Neck 0.0016 0.0015 0.0065 0.0098 0.0006 0.0015 0.0026 0.0006 0.0006 0.0033 0.0002 0.0045 0.0022 0.0009 0.005 0.0004 0.0049 0.0041
Bud Periphery 0.0075 0.0225 0.011 0.0331 0.0181 0.0044 0.0017 0.0085 0.0204 0.0052 0.0039 0.0023 0.0033 0.0092 0.0149 0.0126 0.0011 0.0049
Bud Site 0.0096 0.0453 0.0227 0.0065 0.0026 0.0016 0.0081 0.022 0.0146 0.0032 0.0007 0.0009 0.0032 0.039 0.0105 0.0009 0.001 0.001
Cell Periphery 0.0014 0.002 0.0017 0.0027 0.0004 0.0006 0.0012 0.0008 0.0007 0.0005 0.0002 0.0004 0.001 0.0011 0.0011 0.0005 0.0004 0.0007
Cytoplasm 0.0168 0.03 0.0194 0.01 0.0159 0.0314 0.0184 0.0077 0.0042 0.0022 0.0012 0.0064 0.0172 0.026 0.0249 0.0082 0.0055 0.0215
Cytoplasmic Foci 0.0632 0.0666 0.0688 0.0399 0.091 0.0552 0.0422 0.0334 0.0324 0.028 0.034 0.0284 0.0397 0.0462 0.0549 0.0488 0.0835 0.0462
Eisosomes 0.001 0.0006 0.0009 0.0005 0.0003 0.0004 0.0018 0.0008 0.0006 0.0004 0.0002 0.0004 0.0007 0.0005 0.0007 0.0003 0.0004 0.0004
Endoplasmic Reticulum 0.0031 0.0013 0.0015 0.0009 0.0026 0.0019 0.0039 0.0023 0.0009 0.0005 0.0003 0.0003 0.0028 0.0012 0.0025 0.0008 0.0014 0.0014
Endosome 0.1148 0.0764 0.0937 0.0846 0.1257 0.0756 0.0942 0.0459 0.0416 0.0167 0.0455 0.0259 0.1168 0.0916 0.0706 0.0368 0.0548 0.0631
Golgi 0.0489 0.0388 0.0406 0.0375 0.0321 0.0328 0.0528 0.0651 0.0347 0.035 0.058 0.0382 0.0454 0.0461 0.0377 0.0364 0.0211 0.0384
Lipid Particles 0.0325 0.0064 0.0204 0.0119 0.0554 0.025 0.0319 0.0076 0.0052 0.0037 0.0035 0.0146 0.0428 0.0186 0.0223 0.0371 0.0059 0.025
Mitochondria 0.512 0.5658 0.5288 0.6394 0.4799 0.5936 0.6279 0.7334 0.7586 0.8387 0.7416 0.8108 0.5614 0.576 0.6465 0.622 0.7181 0.6871
None 0.0693 0.0536 0.0597 0.0459 0.0739 0.0754 0.0231 0.0177 0.0045 0.0098 0.0008 0.013 0.0656 0.0267 0.0358 0.142 0.0043 0.034
Nuclear Periphery 0.0125 0.0008 0.0012 0.0009 0.0036 0.0016 0.007 0.0013 0.0004 0.0002 0.0001 0.0001 0.0017 0.0006 0.0024 0.0017 0.0018 0.0014
Nucleolus 0.0055 0.0031 0.0057 0.0015 0.0011 0.002 0.0007 0.0006 0.0007 0.0003 0.0001 0.0002 0.0036 0.0022 0.0008 0.0007 0.0004 0.0009
Nucleus 0.0067 0.0025 0.0031 0.0014 0.0025 0.0031 0.0021 0.0005 0.0008 0.0002 0.0001 0.0001 0.0024 0.001 0.001 0.0006 0.001 0.0011
Peroxisomes 0.0496 0.0352 0.0635 0.0459 0.0523 0.0579 0.0343 0.0346 0.0368 0.0395 0.0818 0.0397 0.0249 0.0611 0.0347 0.0343 0.0625 0.0386
Punctate Nuclear 0.0096 0.0012 0.0041 0.0017 0.0025 0.0068 0.0032 0.0002 0.0029 0.0005 0.0001 0.0003 0.001 0.0003 0.0007 0.0026 0.0009 0.0021
Vacuole 0.016 0.0121 0.012 0.0059 0.0085 0.0095 0.0063 0.004 0.0048 0.0014 0.0018 0.0014 0.0271 0.0164 0.0123 0.0031 0.0015 0.0144
Vacuole Periphery 0.0075 0.0053 0.0044 0.004 0.0044 0.0054 0.0041 0.0025 0.0032 0.0018 0.0018 0.0015 0.0102 0.0061 0.007 0.0031 0.0015 0.0068

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2.3338 0.8345 4.3346 6.3739 7.8672 10.2629 2.7422 11.9591 15.9036 6.2534
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1882 1216 1382 1551 1882 1349 2221 1544 3764 2565 3603 3095

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 642.16 650.34 1014.47 1041.40 659.52 718.63 902.54 946.15 650.84 686.26 945.47 993.88
Standard Deviation 83.48 105.67 237.10 240.49 76.51 99.54 143.79 210.99 80.54 108.01 193.06 231.21
Intensity Change Log 2 — 0.018261 0.659721 0.697520 — 0.123833 0.452574 0.520653 — 0.072716 0.558483 0.610616

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000538 0.001433 0.001488 0.018723 0.000455 0.001390 0.006062 0.011062 0.000497 0.001410 0.004307 0.014901
Bud Neck 0.026804 0.023665 0.004937 0.005142 0.035047 0.024121 0.012339 0.009802 0.030926 0.023905 0.009500 0.007467
Bud Site 0.018715 0.031212 0.018052 0.089202 0.022580 0.024402 0.089472 0.105829 0.020648 0.027630 0.062078 0.097497
Cell Periphery 0.000524 0.000856 0.000485 0.001643 0.000281 0.000539 0.000402 0.002421 0.000403 0.000689 0.000434 0.002031
Cytoplasm 0.062296 0.023186 0.005578 0.022499 0.071123 0.033662 0.039223 0.040201 0.066710 0.028696 0.026318 0.031330
Cytoplasmic Foci 0.179131 0.085861 0.031432 0.031157 0.216927 0.131745 0.047371 0.047015 0.198029 0.109992 0.041257 0.039068
Eisosomes 0.000324 0.000155 0.000069 0.000148 0.000182 0.000163 0.000092 0.000165 0.000253 0.000159 0.000083 0.000156
Endoplasmic Reticulum 0.001838 0.000897 0.001203 0.001649 0.001562 0.000874 0.002293 0.001519 0.001700 0.000885 0.001875 0.001584
Endosome 0.067551 0.103544 0.055497 0.036427 0.074525 0.102396 0.044777 0.053608 0.071038 0.102940 0.048889 0.044998
Golgi 0.085537 0.092724 0.059835 0.103354 0.062483 0.108054 0.062655 0.094514 0.074010 0.100786 0.061574 0.098944
Lipid Particles 0.025477 0.008245 0.003413 0.000398 0.014562 0.010474 0.000706 0.000854 0.020019 0.009417 0.001744 0.000625
Mitochondria 0.427557 0.497772 0.580578 0.532311 0.364678 0.431907 0.475424 0.484735 0.396117 0.463132 0.515758 0.508577
Mitotic Spindle 0.004592 0.018141 0.044152 0.058541 0.011072 0.019497 0.096125 0.035143 0.007832 0.018854 0.076190 0.046868
None 0.001862 0.003676 0.001040 0.000658 0.001020 0.001364 0.000588 0.000665 0.001441 0.002460 0.000761 0.000661
Nuclear Periphery 0.000533 0.000343 0.003714 0.000206 0.000478 0.000349 0.000295 0.000172 0.000506 0.000347 0.001607 0.000189
Nuclear Periphery Foci 0.000238 0.000733 0.004003 0.000335 0.000334 0.000670 0.000313 0.000243 0.000286 0.000700 0.001728 0.000289
Nucleolus 0.001108 0.003615 0.001856 0.000378 0.002263 0.002113 0.000403 0.000287 0.001686 0.002825 0.000960 0.000333
Nucleus 0.010673 0.006693 0.002096 0.003184 0.016668 0.005164 0.007363 0.002064 0.013670 0.005889 0.005343 0.002626
Peroxisomes 0.030073 0.044852 0.008924 0.019545 0.036597 0.048250 0.034462 0.036797 0.033335 0.046639 0.024666 0.028152
Vacuole 0.034570 0.031351 0.079580 0.042735 0.049151 0.035057 0.056738 0.044581 0.041861 0.033300 0.065499 0.043656
Vacuole Periphery 0.020059 0.021047 0.092068 0.031766 0.018013 0.017809 0.022897 0.028323 0.019036 0.019344 0.049429 0.030048

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.07 -4.61 -9.47 -8.95 -8.92 -2.97 -8.14 -8.79 -7.77 -3.59 -4.67 -8.80 -12.67 -11.71 -8.70
Bud Neck 1.08 11.13 10.80 8.01 -0.53 3.79 10.06 11.45 6.40 2.49 3.43 14.02 15.73 10.24 2.93
Bud Site -4.12 0.08 -15.03 -11.62 -15.05 -0.81 -19.15 -17.19 -16.20 -2.91 -3.66 -17.19 -22.77 -19.72 -9.24
Cell Periphery -2.00 0.42 -4.72 -2.80 -4.76 -3.49 -3.04 -4.15 -3.62 -3.92 -3.27 -0.73 -5.75 -4.56 -5.64
Cytoplasm 10.13 18.09 10.59 -0.34 -9.02 9.05 7.52 6.80 -2.02 -0.02 13.37 14.68 11.98 -1.69 -2.27
Cytoplasmic Foci 16.68 32.10 32.93 14.34 0.13 13.12 33.06 32.09 17.45 0.08 20.26 45.10 45.55 22.52 1.12
Eisosomes 8.16 13.05 8.70 0.65 -8.84 1.61 10.59 1.48 -0.15 -7.63 7.85 15.87 8.28 0.35 -11.24
Endoplasmic Reticulum 3.43 2.27 0.41 -4.29 -2.62 2.02 -1.67 0.07 -3.27 2.04 3.72 -0.79 0.31 -5.30 1.19
Endosome -7.05 3.45 10.41 14.20 6.56 -5.90 9.78 5.85 10.55 -3.06 -9.20 9.86 11.16 17.57 1.94
Golgi -1.33 5.63 -3.02 -1.65 -7.75 -9.08 0.25 -6.58 2.34 -6.83 -7.34 4.61 -6.59 0.57 -10.38
Lipid Particles 8.17 11.97 14.25 7.50 5.40 2.49 13.07 12.89 7.84 -0.53 7.88 17.36 18.81 10.82 4.79
Mitochondria -5.32 -12.45 -8.10 -2.24 4.04 -5.56 -9.58 -9.77 -3.83 -1.20 -7.48 -14.11 -12.60 -4.45 0.71
Mitotic Spindle -6.00 -11.71 -15.12 -9.79 -3.10 -3.61 -22.02 -8.98 -4.97 13.64 -6.83 -25.10 -17.41 -10.77 8.39
None -1.93 1.57 2.27 3.59 3.26 -1.20 3.67 2.13 2.39 -0.34 -2.13 2.53 2.84 4.22 1.17
Nuclear Periphery 0.99 -5.15 2.98 0.79 5.74 0.71 1.37 3.15 1.09 3.07 1.21 -4.58 4.32 1.33 6.07
Nuclear Periphery Foci -1.69 -4.51 -2.08 1.30 4.37 -0.91 -0.08 1.19 1.17 1.46 -1.77 -4.50 -0.28 1.72 4.46
Nucleolus -3.39 -1.75 2.87 4.26 3.56 0.27 4.29 4.76 4.03 1.58 -2.46 2.62 5.54 5.76 3.72
Nucleus 2.36 8.09 4.66 1.69 -2.14 7.91 4.19 10.73 4.17 6.12 7.21 6.47 10.85 3.31 3.87
Peroxisomes -4.48 10.27 4.19 7.40 -4.85 -3.42 0.84 -0.09 2.85 -0.76 -5.61 4.72 2.41 7.00 -1.70
Vacuole 1.08 -12.13 -3.24 -4.15 8.44 4.48 -3.72 0.77 -3.28 4.10 4.02 -10.84 -1.67 -5.17 8.38
Vacuole Periphery -0.51 -18.69 -5.13 -4.39 14.44 0.12 -2.95 -5.10 -4.97 -2.64 -0.24 -16.36 -7.23 -6.64 9.01
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages mitochondrion (77%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Om45

Om45


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Om45-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available