Standard name
Human Ortholog
Description Pantothenate synthase; also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.95 – 1.0 0.97 0.97 0.91 0.81 0.75 0.69 0.75 0.73 0.66 0.98 0.97 1.0 0.94 0.94 0.96 0.94 0.9 0.88 0.94 0.93 0.93
Endoplasmic Reticulum 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 – 0 0 0 0 0.05 0 0.14 0.12 0.22 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 – 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0.05 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 – 0 0 0 0.05 0.12 0.17 0.19 0.12 0.12 0.2 0 0 0 0.08 0.05 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 – 0 0 0 0 2 0 0 1 1 2 0 0 0 0 1 0 0 0 0 0 0 1
Bud 0 – 0 0 0 1 1 3 1 1 4 1 0 0 0 1 0 0 0 0 0 0 0 1
Bud Neck 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 – 0 0 3 7 6 8 3 6 6 6 2 2 3 2 7 11 0 0 0 0 1 0
Cytoplasm 207 – 20 195 242 204 316 253 151 161 157 199 203 204 214 301 171 311 206 29 69 86 230 325
Endoplasmic Reticulum 1 – 0 1 1 4 13 11 5 6 0 12 1 0 0 4 4 9 0 0 0 0 3 5
Endosome 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0
Mitochondria 2 – 0 0 0 0 21 14 31 25 48 26 0 0 0 0 0 1 0 0 0 0 0 1
Nucleus 4 – 0 2 1 9 7 8 5 9 6 15 3 0 1 4 3 1 3 0 3 1 0 1
Nuclear Periphery 1 – 0 0 0 0 0 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 1 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 8 – 0 3 9 12 45 56 42 25 27 59 0 9 1 24 9 12 2 1 2 0 3 3
Unique Cell Count 218 20 201 250 224 389 336 219 216 216 300 207 210 214 319 182 324 221 33 79 92 248 349
Labelled Cell Count 226 20 201 256 237 412 353 238 236 249 323 209 215 219 337 195 346 221 33 79 92 248 349


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 13.1 – 11.7 13.5 12.2 10.8 9.7 10.4 9.0 9.0 7.9 9.0 16.5 15.7 15.7 20.5 22.4 22.5 12.8 14.0 14.5
Std Deviation (1e-4) 2.3 – 1.7 2.3 1.9 1.7 1.7 2.1 2.0 1.6 1.5 1.8 2.6 2.8 2.5 4.5 4.6 4.8 2.7 3.4 3.1
Intensity Change (Log2) – – – 0.2 0.06 -0.12 -0.27 -0.17 -0.39 -0.39 -0.56 -0.38 0.49 0.42 0.42 0.81 0.94 0.94 0.13 0.26 0.31


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.8 -0.8 -1.4 -2.1 -2.5 -2.9 -2.6 -2.7 -3.1 -0.6 -0.8 0 -1.1 -1.1 -0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.6277 14.6841 12.7156 12.6944 10.9683 12.9288 10.0857 13.2876 11.7158 10.7818 8.4008 11.6715 9.716 13.1389 12.5628 9.931 10.7581 10.7476
Actin 0.0145 0.0002 0.0061 0.0013 0.0322 0.0017 0.0163 0.0001 0.0013 0.01 0.0424 0.0007 0.0128 0.0002 0.0021 0.038 0.0235 0.0106
Bud 0.0024 0.0004 0.0021 0.0025 0.0262 0.0002 0.0004 0.0001 0.0001 0.0004 0.0021 0.0002 0.0021 0.0001 0.0001 0.0014 0.0002 0.001
Bud Neck 0.0021 0.0004 0.002 0.0005 0.001 0.004 0.0009 0.0002 0.0003 0.0044 0.0021 0.0009 0.0009 0.0001 0.0002 0.0028 0.0005 0.0028
Bud Periphery 0.0009 0.0003 0.001 0.0007 0.0094 0.0003 0.0003 0 0 0.0003 0.0014 0.0001 0.002 0 0.0001 0.0026 0.0001 0.0013
Bud Site 0.0025 0.0005 0.0038 0.0011 0.0035 0.0001 0.0007 0.0001 0.0002 0.0012 0.0024 0.0001 0.0039 0 0.0003 0.0031 0.0014 0.0012
Cell Periphery 0.0002 0 0.0001 0.0001 0.0004 0 0.0001 0 0 0.0001 0.0002 0 0.0002 0 0 0.0004 0.0001 0.0002
Cytoplasm 0.8654 0.9637 0.8941 0.9262 0.7118 0.9248 0.8785 0.9771 0.9384 0.8384 0.7626 0.9438 0.8408 0.9889 0.9675 0.7435 0.9115 0.902
Cytoplasmic Foci 0.0133 0.0019 0.0143 0.0085 0.0099 0.0034 0.0176 0.0006 0.013 0.0254 0.0283 0.0035 0.0227 0.0006 0.0016 0.0436 0.0092 0.0079
Eisosomes 0.0001 0 0 0 0.0002 0 0.0002 0 0 0.0001 0.0012 0 0.0001 0 0 0.0003 0.0001 0.0001
Endoplasmic Reticulum 0.0073 0.0012 0.0053 0.0018 0.0142 0.0032 0.0038 0.0005 0.0019 0.0028 0.0036 0.0015 0.0037 0.0004 0.0046 0.0035 0.0023 0.0034
Endosome 0.0175 0.0012 0.0212 0.0167 0.0597 0.0062 0.0172 0.0002 0.0044 0.0252 0.0218 0.0034 0.0216 0.0002 0.0049 0.021 0.0046 0.0115
Golgi 0.0053 0.0001 0.0053 0.0036 0.0362 0.0014 0.0041 0 0.0009 0.0053 0.0143 0.002 0.005 0 0.0007 0.0171 0.0044 0.0044
Lipid Particles 0.0037 0 0.0025 0.0003 0.0163 0.0009 0.0054 0 0.0016 0.005 0.0347 0.0026 0.0088 0 0.0003 0.0148 0.0043 0.006
Mitochondria 0.0027 0.0002 0.005 0.0018 0.0306 0.0016 0.0023 0.0001 0.0003 0.0045 0.0203 0.0012 0.0095 0.0001 0.0024 0.0374 0.0021 0.012
None 0.0078 0.001 0.0032 0.0016 0.0022 0.0016 0.0058 0.0005 0.0018 0.0096 0.0036 0.0008 0.0046 0.0005 0.0011 0.0006 0.013 0.0017
Nuclear Periphery 0.0095 0.0023 0.0054 0.003 0.0079 0.0044 0.0052 0.0011 0.0028 0.0077 0.0064 0.0033 0.0088 0.0012 0.0035 0.0028 0.0017 0.0081
Nucleolus 0.0003 0.0001 0.0002 0.0001 0.0016 0.0001 0.0002 0 0.0001 0.0004 0.0004 0.0001 0.001 0 0 0.0003 0.0001 0.0011
Nucleus 0.036 0.0245 0.0201 0.0272 0.0192 0.0416 0.0313 0.0191 0.0255 0.0305 0.0275 0.0337 0.0282 0.0075 0.0093 0.0073 0.0047 0.0149
Peroxisomes 0.0024 0 0.003 0.0007 0.0057 0.0001 0.0042 0 0.0027 0.0235 0.0192 0.0006 0.0074 0 0.0001 0.0549 0.013 0.0037
Punctate Nuclear 0.0031 0.0007 0.0026 0.0006 0.0016 0.0016 0.0027 0.0003 0.0042 0.0019 0.0027 0.0009 0.0066 0.0001 0.0004 0.0008 0.0007 0.0033
Vacuole 0.002 0.0011 0.0022 0.0015 0.0061 0.002 0.0021 0.0001 0.0003 0.0023 0.0016 0.0005 0.0068 0.0001 0.0005 0.0021 0.002 0.0018
Vacuole Periphery 0.0009 0.0001 0.0006 0.0004 0.0038 0.0006 0.0007 0 0.0001 0.001 0.0012 0.0002 0.0023 0 0.0004 0.0016 0.0005 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 47.4583 42.4248 48.0086 42.7969 39.2265 33.2024 52.5472 38.7229 55.5386 46.1731
Translational Efficiency 0.9153 1.1212 1.0081 1.1772 1.0806 1.4132 0.912 1.2357 0.8743 1.0327

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1794 842 2055 857 1538 1768 63 972 3332 2610 2118 1829

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1286.94 1495.70 1707.57 1833.97 1264.78 1396.37 1944.83 1762.88 1276.71 1428.41 1714.63 1796.19
Standard Deviation 198.65 268.72 235.06 284.47 181.97 223.59 292.06 305.38 191.45 243.55 240.36 297.89
Intensity Change Log 2 — 0.216876 0.408000 0.511025 — 0.142795 0.620758 0.479048 — 0.180632 0.517375 0.495264

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000156 0.000191 0.000858 0.007965 0.000147 0.000156 0.027223 0.000521 0.000151 0.000167 0.001642 0.004009
Bud Neck 0.000346 0.000429 0.000956 0.006361 0.000409 0.000741 0.008986 0.005656 0.000375 0.000641 0.001195 0.005986
Bud Site 0.002545 0.001731 0.004829 0.017508 0.002188 0.004036 0.034688 0.020415 0.002380 0.003292 0.005717 0.019053
Cell Periphery 0.000044 0.000087 0.000093 0.000263 0.000059 0.000046 0.000503 0.000146 0.000051 0.000059 0.000105 0.000201
Cytoplasm 0.880871* 0.848139* 0.728833* 0.571655* 0.831232* 0.840492* 0.364044* 0.591494* 0.857958* 0.842959* 0.717982* 0.582198*
Cytoplasmic Foci 0.022120 0.013011 0.004684 0.023143 0.018242 0.014732 0.016399 0.020319 0.020330 0.014177 0.005032 0.021642
Eisosomes 0.000003 0.000003 0.000002 0.000014 0.000004 0.000003 0.000047 0.000015 0.000003 0.000003 0.000004 0.000015
Endoplasmic Reticulum 0.000424 0.000795 0.000119 0.000382 0.001570 0.000447 0.002683 0.000845 0.000953 0.000559 0.000196 0.000628
Endosome 0.000616 0.000627 0.000916 0.014728 0.000867 0.001249 0.008933 0.016139 0.000732 0.001049 0.001155 0.015477
Golgi 0.000991 0.000531 0.003483 0.016033 0.000305 0.001733 0.002974 0.021323 0.000674 0.001345 0.003468 0.018844
Lipid Particles 0.000288 0.000413 0.000503 0.002854 0.000425 0.000940 0.023444 0.001095 0.000351 0.000770 0.001185 0.001919
Mitochondria 0.000185 0.001503 0.000567 0.001919 0.000089 0.000878 0.000313 0.004864 0.000141 0.001080 0.000559 0.003484
Mitotic Spindle 0.002235 0.002203 0.006497 0.032151 0.001744 0.007478 0.075604 0.094192 0.002008 0.005776 0.008553 0.065122
None 0.005644 0.009535 0.007748 0.006580 0.006389 0.006688 0.002956 0.007862 0.005988 0.007606 0.007606 0.007261
Nuclear Periphery 0.000059 0.000111 0.000178 0.000519 0.000450 0.000160 0.001130 0.000735 0.000239 0.000144 0.000207 0.000634
Nuclear Periphery Foci 0.002585 0.004542 0.001282 0.002720 0.004543 0.002797 0.009988 0.004356 0.003488 0.003360 0.001541 0.003589
Nucleolus 0.000106 0.000118 0.000090 0.005546 0.000110 0.000220 0.000359 0.001077 0.000108 0.000187 0.000098 0.003171
Nucleus 0.068641 0.106083 0.223544* 0.246406* 0.107829 0.096830 0.290129* 0.136061* 0.086730 0.099815 0.225525* 0.187765*
Peroxisomes 0.000101 0.000111 0.000299 0.000701 0.000052 0.000182 0.000598 0.002483 0.000078 0.000159 0.000308 0.001648
Vacuole 0.011457 0.008941 0.012640 0.038062 0.023019 0.018465 0.128746 0.056984 0.016794 0.015393 0.016094 0.048118
Vacuole Periphery 0.000584 0.000895 0.001878 0.004491 0.000330 0.001726 0.000252 0.013418 0.000467 0.001458 0.001830 0.009235

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.89 -2.40 -2.14 -2.06 -1.11 -0.22 -1.53 -5.43 -5.09 1.45 -1.00 -2.76 -2.50 -2.43 -0.11
Bud Neck -3.09 -11.18 -8.87 -8.35 -6.05 -3.14 -6.79 -9.81 -8.26 5.45 -4.17 -11.82 -13.04 -11.44 -6.33
Bud Site 1.29 -2.35 -5.38 -6.50 -3.30 -1.82 -4.57 -6.45 -4.48 2.68 -1.30 -3.39 -8.36 -6.75 -3.93
Cell Periphery -6.20 -12.26 -11.86 -9.66 -7.64 2.54 -5.09 -9.16 -10.03 4.17 -2.43 -12.22 -14.85 -13.87 -5.92
Cytoplasm 6.82 37.82 40.00 32.22 15.36 -0.87 16.52 26.60 27.34 -8.51 5.15 35.24 46.71 41.36 14.71
Cytoplasmic Foci 4.86 11.71 5.10 -0.02 -6.56 2.37 0.02 4.04 1.73 1.94 5.28 14.19 6.67 1.27 -7.96
Eisosomes -0.48 -3.05 -10.19 -9.15 -8.45 1.10 -4.67 -6.38 -7.17 3.83 -0.18 -3.34 -11.76 -11.44 -8.16
Endoplasmic Reticulum -0.99 4.81 3.02 1.55 -3.78 2.42 -0.23 2.87 3.35 4.28 1.70 3.46 3.27 2.68 -1.58
Endosome 0.02 0.52 -2.10 -2.07 -2.22 -1.29 -3.64 -2.64 -2.07 1.76 -1.56 0.77 -3.38 -2.72 -3.55
Golgi 1.35 -0.89 -1.15 -1.80 -0.43 -1.92 -1.87 -2.22 -0.87 -1.58 -1.13 -1.52 -2.38 -1.39 -0.87
Lipid Particles -2.09 -9.57 -5.76 -5.44 -4.39 -0.76 -5.08 -11.41 -2.56 4.44 -1.01 -9.31 -8.58 -4.97 -4.43
Mitochondria -1.18 -1.55 -1.41 0.95 -0.19 -1.55 -4.44 -2.39 0.15 -0.49 -1.87 -2.48 -2.71 0.87 -1.06
Mitotic Spindle 0.09 -2.98 -6.10 -5.92 -4.40 -3.04 -2.57 -7.08 -5.33 1.38 -2.73 -4.36 -9.12 -7.03 -6.05
None -3.21 -2.27 -2.63 1.65 -1.17 -0.02 3.46 -0.53 -0.60 -4.24 -2.39 -1.83 -2.30 0.53 -0.91
Nuclear Periphery -2.70 -22.00 -22.53 -16.99 -13.29 1.18 -5.46 -1.65 -14.75 5.32 0.69 -1.78 -5.61 -22.37 -12.32
Nuclear Periphery Foci -3.84 2.91 -2.06 2.77 -5.14 3.51 -3.03 4.20 0.94 3.97 -0.13 5.15 2.28 2.24 -3.27
Nucleolus -0.73 -1.06 -1.22 -1.18 -1.19 -2.50 -4.25 -3.69 -1.11 1.13 -2.64 -1.99 -1.63 -1.26 -1.54
Nucleus -10.09 -41.96 -23.26 -15.40 3.79 2.12 -3.11 -7.59 -9.54 1.40 -6.23 -37.67 -22.63 -18.06 11.47
Peroxisomes -0.36 -0.69 -1.47 -0.65 0.15 -3.01 -3.82 -2.53 -1.47 -0.30 -2.40 -1.01 -2.76 -1.49 -0.77
Vacuole 0.28 -12.84 -22.72 -22.53 -18.80 0.43 -9.00 -21.39 -21.80 4.22 -1.36 -10.59 -31.20 -30.47 -24.46
Vacuole Periphery -0.35 -0.50 -0.04 0.33 0.49 -2.00 0.54 -1.65 -0.08 -1.75 -1.74 -0.86 -1.43 0.27 -0.57
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Pantothenate synthase; also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Pan6

Pan6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pan6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available