Standard name
Human Ortholog
Description Ubiquitin-specific protease that cleaves ubiquitin-protein fusions; UBP7 has a paralog, UBP11, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0.05 0 0 0 0 0 0.05 0.07
Bud 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0.06 0.07 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0.09 0.1 0 0 0 0 0 0
Cytoplasm 0.96 0.94 0.94 0.96 0.98 0.95 0.92 0.87 0.83 0.83 0.77 0.72 0.97 0.92 0.94 0.93 0.9 0.88 0.82 0.93 0.81 0.84 0.78 0.75
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.1 0.06 0.07 0.05 0.14 0.22 0.24 0.41 0.38 0.44 0.45 0 0 0 0.07 0 0 0 0 0.1 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 0 0 0 0 0 0 0 1 16 10 0 5 4 0 1 4 5 10 17
Bud 0 3 4 8 3 5 4 16 13 11 14 12 0 17 24 0 3 3 0 0 0 2 5 4
Bud Neck 0 0 0 1 0 1 1 2 2 1 1 2 0 0 0 1 1 0 3 1 1 6 10 9
Bud Site 0 0 0 0 0 0 1 0 1 3 2 0 0 3 2 0 0 1 – – – – – –
Cell Periphery 4 3 9 3 8 5 6 3 6 3 3 9 0 8 24 3 10 16 0 1 2 1 1 2
Cytoplasm 94 131 212 370 387 419 514 532 367 423 232 300 103 248 331 107 95 144 85 146 195 145 168 182
Endoplasmic Reticulum 1 2 0 3 1 2 0 1 0 1 1 0 0 1 3 6 2 8 1 0 2 1 0 3
Endosome 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 2 0 2 1 1 1 1 4 6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 0 0 1
Mitochondria 3 14 13 26 19 61 123 145 183 195 132 186 1 2 4 8 0 4 4 2 24 3 6 7
Nucleus 1 0 0 2 0 1 4 3 1 2 3 3 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 1 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 1 0 0 0 1 0 1 0 1 0 0 0 1 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 1 1 3 1 2 0 1 0 0 1 1 2 4 0 0 1 0 0 1
Vac/Vac Membrane 0 0 0 0 0 2 2 5 0 2 2 0 0 0 0 3 2 6 2 1 3 3 2 3
Unique Cell Count 98 140 225 387 394 441 559 614 441 508 302 414 106 269 353 115 106 164 104 158 241 174 215 244
Labelled Cell Count 104 153 238 415 419 498 657 714 574 644 390 514 106 295 400 132 120 194 104 158 241 174 215 244


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 4.1 3.6 3.6 3.8 3.6 3.4 3.6 3.0 3.0 3.1 2.7 5.0 5.2 4.6 6.5 6.6 7.2 5.1 4.9 5.4
Std Deviation (1e-4) 0.5 0.5 0.5 1.1 1.2 1.2 1.4 1.4 1.1 1.2 1.1 0.9 1.3 1.1 1.0 1.8 2.1 2.3 1.2 1.0 1.5
Intensity Change (Log2) – – – 0.01 0.07 -0.01 -0.08 0.0 -0.26 -0.26 -0.21 -0.4 0.49 0.54 0.36 0.86 0.88 1.02 0.52 0.44 0.59


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4757 1.4495 1.3728 1.3412 1.0412 1.3498 2.1081 2.1548 1.9836 1.6057 2.5482 2.2587 1.418 1.9291 1.2956 1.0536 1.0936 1.3594
Actin 0.0607 0.0102 0.0101 0.0425 0.0039 0.0075 0.0446 0.0047 0.0216 0.0291 0.0329 0.0202 0.0407 0.0013 0.0169 0.0012 0.0024 0.0193
Bud 0.0007 0.0017 0.004 0.0016 0.0001 0.0002 0.0015 0.0009 0.0052 0.0024 0.0034 0.0005 0.0006 0.0003 0.0019 0.0003 0.0006 0.0001
Bud Neck 0.0038 0.0019 0.003 0.0042 0.0014 0.029 0.002 0.0011 0.0015 0.0006 0.0042 0.0217 0.0034 0.0006 0.0024 0.0003 0.0005 0.0062
Bud Periphery 0.0013 0.0022 0.0168 0.0022 0.0002 0.0005 0.0022 0.0017 0.0117 0.0023 0.0041 0.0016 0.0009 0.0003 0.0044 0.0006 0.0022 0.0002
Bud Site 0.0081 0.075 0.0096 0.0252 0.0003 0.0005 0.014 0.0348 0.0174 0.0011 0.0053 0.0003 0.0267 0.0101 0.0088 0.0003 0.0002 0.0002
Cell Periphery 0.0025 0.0057 0.0029 0.0013 0.0004 0.0009 0.0009 0.001 0.0008 0.0002 0.0007 0.0002 0.0087 0.0015 0.0021 0.0003 0.0014 0.0005
Cytoplasm 0.4024 0.6174 0.5805 0.5804 0.6039 0.7323 0.3567 0.5731 0.5722 0.5393 0.4542 0.6158 0.4497 0.321 0.3568 0.3783 0.3146 0.5512
Cytoplasmic Foci 0.0153 0.0061 0.0395 0.0138 0.0327 0.017 0.0405 0.006 0.0108 0.0262 0.0494 0.0074 0.0515 0.0207 0.0533 0.0062 0.0063 0.0073
Eisosomes 0.0007 0.0003 0.0003 0.0005 0.0001 0.0001 0.0006 0.0002 0.0002 0 0.0003 0.0001 0.0003 0.0002 0.0014 0.0001 0.0002 0.0002
Endoplasmic Reticulum 0.0121 0.0059 0.0053 0.0118 0.0062 0.0017 0.0126 0.0019 0.0025 0.0021 0.0039 0.0043 0.0072 0.0049 0.0098 0.0009 0.0046 0.0027
Endosome 0.0169 0.0026 0.0094 0.0236 0.0189 0.0005 0.0487 0.0023 0.0138 0.0126 0.0715 0.0049 0.006 0.0068 0.0218 0.0009 0.0014 0.0065
Golgi 0.0144 0.0014 0.004 0.0067 0.0044 0.0005 0.0178 0.003 0.0087 0.0062 0.0659 0.0027 0.0072 0.001 0.0082 0.0003 0.0003 0.0136
Lipid Particles 0.0189 0.001 0.0126 0.0056 0.0447 0.0009 0.0199 0.0004 0.0059 0.0006 0.0325 0.0004 0.0142 0.0014 0.0159 0.0001 0.0007 0.0033
Mitochondria 0.011 0.0002 0.0092 0.0026 0.0028 0.0002 0.0184 0.0029 0.0043 0.0066 0.0253 0.0014 0.0008 0.0002 0.0049 0.0002 0.0001 0.0019
None 0.3684 0.2643 0.2812 0.2395 0.2182 0.1875 0.354 0.3634 0.3127 0.341 0.2168 0.2969 0.3123 0.6204 0.4676 0.6084 0.6628 0.3844
Nuclear Periphery 0.0096 0.0005 0.0009 0.0102 0.0028 0.0001 0.0157 0.0002 0.001 0.0003 0.0039 0.0088 0.0004 0.0006 0.0031 0.0001 0.0003 0.0003
Nucleolus 0.0138 0.0002 0.001 0.0022 0.0005 0 0.0015 0.0001 0.0003 0 0.0007 0.0013 0.0024 0.0004 0.0009 0.0001 0.0001 0
Nucleus 0.0204 0.0008 0.0012 0.0042 0.0008 0.0004 0.0145 0.0005 0.0009 0.0004 0.0025 0.0075 0.0018 0.0007 0.0018 0.0004 0.0003 0.0002
Peroxisomes 0.0086 0.0001 0.0031 0.0023 0.0281 0.019 0.0158 0.0006 0.0033 0.027 0.012 0.0005 0.0382 0.0001 0.0082 0.0001 0.0001 0.0008
Punctate Nuclear 0.0057 0.0004 0.0031 0.012 0.0278 0.0004 0.0102 0.0002 0.002 0.0003 0.003 0.0022 0.0014 0.0003 0.0021 0.0002 0.0002 0.0002
Vacuole 0.003 0.0019 0.0019 0.0063 0.0013 0.0005 0.0057 0.0008 0.0026 0.0014 0.005 0.0006 0.0251 0.0072 0.0068 0.0004 0.0005 0.0006
Vacuole Periphery 0.0016 0.0001 0.0005 0.0014 0.0004 0 0.0021 0.0001 0.0005 0.0002 0.0026 0.0005 0.0004 0.0001 0.0009 0 0 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.1507 11.0415 7.2829 13.9943 10.6762 12.6876 12.7922 18.3142 13.9301 19.0434
Translational Efficiency 0.6388 0.3404 0.6008 0.3841 0.4464 0.6561 0.4093 0.3736 0.5075 0.3755

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1662 381 304 1162 1299 1507 675 68 2961 1888 979 1230

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 623.65 730.45 1059.00 854.04 615.71 752.11 949.98 928.27 620.17 747.74 983.83 858.14
Standard Deviation 70.55 95.73 97.93 115.24 98.76 94.82 98.83 113.56 84.19 95.40 110.71 116.39
Intensity Change Log 2 — 0.228049 0.763894 0.453567 — 0.288693 0.625646 0.592293 — 0.258495 0.696868 0.524153

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000461 0.002156 0.002283 0.001691 0.000605 0.002503 0.000291 0.001114 0.000524 0.002433 0.000910 0.001660
Bud Neck 0.027143 0.036709 0.005283 0.014220 0.015091 0.042573 0.004271 0.005789 0.021856 0.041389 0.004585 0.013754
Bud Site 0.010158 0.052818 0.040615 0.040661 0.016897 0.040908 0.007150 0.046516 0.013114 0.043312 0.017542 0.040985
Cell Periphery 0.000244 0.000217 0.000586 0.000329 0.000530 0.000341 0.000263 0.000309 0.000370 0.000316 0.000363 0.000328
Cytoplasm 0.509057* 0.305932* 0.374346* 0.478332* 0.507548* 0.436598* 0.492324* 0.449371* 0.508395* 0.410230* 0.455690* 0.476731*
Cytoplasmic Foci 0.220143* 0.315212* 0.046670 0.054593 0.243643* 0.259516* 0.040345 0.044324 0.230453* 0.270755* 0.042309 0.054026
Eisosomes 0.000469 0.000336 0.000159 0.000179 0.000233 0.000641 0.000097 0.000157 0.000365 0.000579 0.000116 0.000178
Endoplasmic Reticulum 0.001073 0.000979 0.010905 0.001404 0.001666 0.000841 0.002333 0.002814 0.001333 0.000869 0.004995 0.001482
Endosome 0.019216 0.078601 0.011202 0.016093 0.021007 0.036885 0.004257 0.002635 0.020002 0.045304 0.006414 0.015349
Golgi 0.003662 0.012911 0.000242 0.003488 0.004274 0.014737 0.000094 0.000131 0.003930 0.014368 0.000140 0.003302
Lipid Particles 0.010910 0.009455 0.005789 0.002329 0.012779 0.005714 0.002065 0.001462 0.011730 0.006469 0.003221 0.002281
Mitochondria 0.006595 0.004424 0.000288 0.007096 0.003875 0.009017 0.000326 0.000066 0.005402 0.008090 0.000314 0.006708
Mitotic Spindle 0.000338 0.002070 0.003237 0.025396 0.000646 0.005111 0.001506 0.000618 0.000473 0.004497 0.002044 0.024026
None 0.003877 0.001539 0.001252 0.005738 0.009671 0.001046 0.007068 0.000682 0.006419 0.001145 0.005262 0.005459
Nuclear Periphery 0.000235 0.000145 0.001592 0.000503 0.000564 0.000115 0.000920 0.000627 0.000379 0.000121 0.001129 0.000510
Nuclear Periphery Foci 0.000365 0.000480 0.010801 0.001306 0.001226 0.000434 0.001801 0.001586 0.000743 0.000443 0.004595 0.001321
Nucleolus 0.000971 0.000655 0.000272 0.001087 0.001903 0.000560 0.000319 0.000089 0.001380 0.000580 0.000304 0.001032
Nucleus 0.085546 0.016180 0.176239* 0.095166 0.079759 0.027142 0.253114* 0.089328 0.083007 0.024930 0.229242* 0.094843
Peroxisomes 0.006024 0.040248 0.001262 0.006864 0.006699 0.017382 0.000621 0.000627 0.006320 0.021996 0.000820 0.006519
Vacuole 0.092254 0.115750 0.306696* 0.241666* 0.070032 0.095722 0.180678 0.351686* 0.082505 0.099764 0.219809* 0.247749*
Vacuole Periphery 0.001260 0.003184 0.000282 0.001856 0.001350 0.002214 0.000159 0.000070 0.001299 0.002410 0.000197 0.001758

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.54 -3.01 -2.63 1.74 1.01 -4.62 1.67 -1.17 2.85 -1.85 -5.73 -1.97 -2.59 2.59 -1.38
Bud Neck -2.08 12.22 8.90 6.50 -2.47 -10.77 7.30 6.68 15.41 1.04 -8.71 14.13 8.39 14.45 -3.07
Bud Site -7.54 -3.09 -6.41 3.86 0.03 -7.65 4.55 -0.56 1.58 -1.45 -11.94 -0.34 -5.46 4.25 -4.40
Cell Periphery 1.30 -7.47 0.96 -0.46 7.63 0.54 0.88 0.92 2.47 0.31 0.32 0.31 0.97 3.61 4.25
Cytoplasm 14.01 12.70 9.48 -6.35 -5.52 6.81 7.36 4.67 2.79 2.03 12.23 12.79 10.73 0.73 -1.76
Cytoplasmic Foci -8.15 33.84 37.26 25.44 0.23 -1.95 33.98 26.78 29.17 0.07 -6.60 48.15 48.36 44.59 -0.50
Eisosomes 2.30 10.64 11.34 3.81 1.37 -6.46 4.96 2.30 7.64 -1.41 -4.15 12.29 10.90 9.12 -1.52
Endoplasmic Reticulum 0.30 -11.05 -1.66 -2.37 10.86 2.46 -5.17 -1.69 -2.98 1.10 1.73 -11.71 -1.25 -3.03 11.64
Endosome -9.01 6.98 6.47 10.67 1.47 -7.11 12.84 14.50 19.14 4.77 -11.71 15.77 8.11 15.95 -1.33
Golgi -4.06 11.05 2.71 4.81 -1.84 -9.39 12.60 12.54 13.76 -0.86 -10.55 16.72 3.46 10.96 -1.98
Lipid Particles 0.70 5.32 9.31 4.47 8.65 5.57 8.72 9.25 8.32 2.85 5.84 11.01 12.89 8.87 6.26
Mitochondria 1.57 5.29 1.89 0.74 -2.23 -3.48 3.89 4.11 7.69 3.38 -2.21 6.54 1.59 3.23 -2.23
Mitotic Spindle -2.99 -2.26 -6.42 -5.63 -4.69 -4.28 -1.25 -0.58 3.97 0.85 -4.93 -2.58 -6.37 -4.46 -5.53
None 1.78 3.79 0.19 -1.49 -2.89 6.22 2.38 6.20 0.07 2.07 6.72 2.15 2.67 -2.65 -0.01
Nuclear Periphery 2.79 -15.62 -12.20 -13.68 8.08 1.93 -3.11 -0.73 -4.29 3.34 2.48 -9.51 -4.78 -15.00 7.45
Nuclear Periphery Foci -1.66 -13.13 -6.11 -4.67 12.00 3.37 -3.67 -1.32 -3.83 1.56 1.84 -13.00 -3.01 -3.70 11.18
Nucleolus 2.01 5.80 2.33 0.35 -2.42 4.61 6.78 7.66 3.08 4.97 4.41 8.73 4.75 0.27 -2.13
Nucleus 23.30 -9.94 -5.18 -21.52 7.40 14.54 -19.12 -1.12 -3.99 8.18 25.11 -21.50 -5.94 -20.67 16.51
Peroxisomes -6.99 8.70 2.74 7.44 -3.14 -7.94 9.00 9.21 14.59 0.48 -11.03 13.39 3.61 12.12 -3.84
Vacuole -3.08 -18.86 -28.82 -21.00 0.34 -6.19 -17.98 -10.89 -10.20 -6.04 -4.82 -24.16 -32.15 -29.20 -6.88
Vacuole Periphery -3.16 7.82 1.39 3.58 -2.32 -4.46 11.75 12.79 12.90 3.54 -5.65 13.26 1.88 5.31 -2.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ubiquitin-specific protease that cleaves ubiquitin-protein fusions; UBP7 has a paralog, UBP11, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (62%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ubp7

Ubp7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ubp7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available