Standard name
Human Ortholog
Description Putative membrane glycoprotein; has strong similarity to Vth2p and Pep1p/Vps10p; may be involved in vacuolar protein sorting
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.58 0.64 0.69 0.76 0.83 0.89 – 0.85 0.81 0.77 0.74 0.73 0.76 0.81 0.82 – – – 0.15 0.16 0.2 0.17 0.16 0.16
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0.16 0.05 0.05 – – – 0 0 0 0 0 0
Endosome 0.31 0.23 0.19 0.11 0.08 0 – 0 0 0 0 0 0 0.06 0.08 – – – 0.48 0.49 0.39 0.39 0.38 0.36
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0.06 0 0.07 0 0.24 – 0.3 0.4 0.46 0.49 0.48 0 0 0 – – – 0.09 0.11 0.18 0.16 0.15 0.15
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0.05 0 0.15 0.05 0.05 0 – 0 0 0 0 0 0.06 0.05 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0.12 0.08 0 0 0 0 – 0 0 0 0 0 0 0 0.05 – – – 0.16 0.11 0.12 0.15 0.2 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 4 0 0 0 0 – 0 0 0 0 0 5 5 2 – – – 14 25 4 6 8 9
Bud 4 13 4 1 3 4 – 8 6 8 9 7 3 1 0 – – – 8 11 0 5 15 10
Bud Neck 1 0 4 0 0 1 – 4 0 1 1 1 4 5 0 – – – 2 8 2 1 4 2
Bud Site 0 0 0 0 0 0 – 0 0 0 0 3 0 0 0 – – – – – – – – –
Cell Periphery 1 1 0 0 0 2 – 0 0 1 1 2 4 0 0 – – – 0 0 0 0 1 0
Cytoplasm 306 486 217 125 177 243 – 278 257 298 148 160 227 296 293 – – – 93 146 68 71 118 91
Endoplasmic Reticulum 5 27 1 1 0 0 – 2 0 0 0 0 48 19 18 – – – 7 8 5 8 13 16
Endosome 162 176 59 18 17 1 – 2 0 0 0 0 13 21 30 – – – 306 455 135 160 283 202
Golgi 4 3 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – 9 7 2 4 8 2
Mitochondria 19 49 8 12 9 66 – 98 128 177 99 106 0 1 0 – – – 58 104 63 66 110 81
Nucleus 0 2 0 0 0 1 – 3 1 0 1 0 0 0 0 – – – 0 1 0 0 2 0
Nuclear Periphery 1 2 0 0 0 0 – 1 0 1 0 0 0 0 0 – – – 2 3 0 1 1 2
Nucleolus 3 1 1 0 0 1 – 1 1 1 0 0 0 0 0 – – – 0 0 1 0 0 0
Peroxisomes 6 0 6 3 2 0 – 0 0 0 0 0 0 0 1 – – – 2 2 1 0 2 1
SpindlePole 27 21 46 9 11 1 – 2 3 7 1 8 17 17 11 – – – 19 38 12 13 22 17
Vac/Vac Membrane 61 60 13 6 5 5 – 3 0 1 1 1 6 11 17 – – – 102 100 41 61 150 112
Unique Cell Count 525 765 316 164 214 272 328 317 388 201 219 298 365 358 642 930 348 412 753 563
Labelled Cell Count 600 845 359 175 224 325 402 396 495 261 288 327 376 372 642 930 348 412 753 563


Endosome

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.0 4.8 4.3 4.0 3.7 3.1 – 3.1 2.8 2.6 2.6 2.6 5.4 5.7 6.1 4.3 4.9 – 5.8 5.6 5.9
Std Deviation (1e-4) 1.0 0.8 1.3 1.5 1.2 1.6 – 0.9 0.8 1.0 0.8 1.2 0.8 0.8 1.0 1.3 1.5 – 1.4 1.3 1.4
Intensity Change (Log2) – – – -0.09 -0.22 -0.47 – -0.48 -0.6 -0.74 -0.74 -0.73 0.34 0.43 0.5 0.01 0.18 – 0.44 0.39 0.46


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.4973 1.2705 0.8017 0.7522 0.9211 1.1073 3.3038 3.7671 3.7976 3.8194 3.384 3.8835 4.4538 2.7358 2.1067 2.3253 2.6084 2.8623
Actin 0.0038 0.0019 0.0033 0.0022 0.0209 0.001 0.0048 0.0018 0.0082 0.0123 0.0024 0.0055 0.0001 0.0016 0.0006 0.0001 0.0001 0.0047
Bud 0.0007 0.0158 0.0037 0.0048 0.002 0.002 0.0077 0.0058 0.0044 0.0087 0.0086 0.0032 0.0001 0.0003 0.0002 0.0001 0.0001 0.0001
Bud Neck 0.0016 0.0011 0.0003 0.0009 0.0007 0.001 0.0021 0.0011 0.0023 0.0006 0.0017 0.0022 0.0001 0.0004 0.0001 0.0004 0.0002 0.001
Bud Periphery 0.0006 0.0036 0.0015 0.0042 0.0019 0.0007 0.0047 0.0087 0.0038 0.0215 0.0042 0.0025 0.0001 0.0004 0.0002 0.0001 0.0001 0.0001
Bud Site 0.003 0.0204 0.0016 0.0019 0.0011 0.0006 0.0075 0.0131 0.0096 0.0015 0.0017 0.0006 0.0009 0.0014 0.0003 0.0005 0.0001 0.0002
Cell Periphery 0.0003 0.0005 0.0002 0.0002 0.0003 0.0002 0.0005 0.0005 0.0005 0.0002 0.0005 0.0003 0.0006 0.0003 0.0001 0 0.0001 0.0001
Cytoplasm 0.1337 0.1671 0.1383 0.114 0.086 0.1717 0.0475 0.1087 0.0552 0.0442 0.0729 0.0725 0.0388 0.1326 0.0915 0.0728 0.2086 0.1113
Cytoplasmic Foci 0.1835 0.1932 0.1983 0.2138 0.1894 0.2106 0.2164 0.238 0.2331 0.1639 0.2172 0.2762 0.0268 0.1734 0.2017 0.198 0.1698 0.2323
Eisosomes 0.0001 0.0001 0.0001 0 0.0002 0 0.0002 0.0001 0.0002 0.0002 0.0002 0.0001 0.0005 0.0002 0.0001 0 0 0
Endoplasmic Reticulum 0.006 0.0049 0.005 0.0024 0.0038 0.0044 0.0039 0.0037 0.0022 0.0119 0.0037 0.0021 0.0034 0.0066 0.0054 0.0012 0.0056 0.0027
Endosome 0.3961 0.3333 0.3674 0.4228 0.4349 0.3688 0.3527 0.3448 0.3015 0.3605 0.342 0.2777 0.052 0.3163 0.3892 0.2729 0.4106 0.3508
Golgi 0.0195 0.015 0.0212 0.0156 0.0202 0.0221 0.0269 0.0169 0.0298 0.0285 0.0353 0.0191 0.0017 0.0075 0.0293 0.0158 0.0065 0.0246
Lipid Particles 0.0318 0.0116 0.0174 0.0157 0.0206 0.0457 0.0636 0.0318 0.0345 0.0467 0.053 0.0532 0.0302 0.0264 0.009 0.0171 0.0049 0.0421
Mitochondria 0.0052 0.0056 0.0064 0.0038 0.0126 0.0078 0.014 0.0082 0.0174 0.0131 0.0139 0.0069 0.0025 0.0022 0.0049 0.0005 0.001 0.0054
None 0.1673 0.1769 0.1902 0.1416 0.1701 0.1281 0.1909 0.1438 0.2189 0.2328 0.139 0.2179 0.7826 0.293 0.2053 0.3928 0.162 0.1844
Nuclear Periphery 0.0032 0.002 0.0027 0.0016 0.0043 0.0027 0.0053 0.0024 0.0018 0.006 0.0033 0.0015 0.0061 0.0034 0.0019 0.0006 0.0025 0.001
Nucleolus 0.0006 0.0017 0.0006 0.0008 0.0007 0.0004 0.0013 0.003 0.0021 0.001 0.0009 0.0007 0.006 0.001 0.0002 0.0004 0.0002 0.0002
Nucleus 0.0037 0.0057 0.002 0.002 0.0018 0.0015 0.0026 0.0043 0.0038 0.0019 0.0033 0.0013 0.0072 0.001 0.0005 0.0005 0.0007 0.0005
Peroxisomes 0.0117 0.0064 0.0182 0.0066 0.0117 0.0117 0.0249 0.0279 0.0496 0.0228 0.0785 0.0402 0.0009 0.0079 0.044 0.0122 0.001 0.0129
Punctate Nuclear 0.0054 0.0041 0.0022 0.0038 0.0048 0.002 0.005 0.004 0.0049 0.0035 0.0047 0.0043 0.0048 0.0014 0.0009 0.0043 0.001 0.0016
Vacuole 0.0186 0.0247 0.0156 0.0334 0.0091 0.014 0.0141 0.0265 0.0134 0.0127 0.0092 0.0098 0.0313 0.0196 0.0099 0.0086 0.021 0.0208
Vacuole Periphery 0.0034 0.0044 0.0041 0.0078 0.0028 0.003 0.0033 0.0047 0.0028 0.0056 0.0037 0.0023 0.0032 0.0031 0.0047 0.001 0.004 0.0032

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 19.5765 12.9396 18.1016 18.5898 16.1521 22.5302 21.0725 22.5823 22.1021 22.4936
Translational Efficiency 0.2248 0.232 0.1987 0.1776 0.2314 0.1608 0.1852 0.2229 0.1187 0.1904

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
203 1697 457 404 2290 1806 1151 1839 2493 3503 1608 2243

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 800.84 753.56 844.09 849.34 628.98 749.82 716.95 791.06 642.97 751.63 753.08 801.56
Standard Deviation 130.52 106.94 99.98 119.66 338.37 93.57 106.97 112.39 329.79 100.29 119.67 115.92
Intensity Change Log 2 — -0.087792 0.075883 0.084828 — 0.253530 0.188858 0.330773 — 0.072376 0.126674 0.198214

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001419 0.000313 0.000281 0.001378 0.000634 0.000189 0.000567 0.000697 0.000698 0.000249 0.000486 0.000820
Bud Neck 0.015617 0.025864 0.026792 0.014202 0.050375 0.028009 0.026259 0.031202 0.047545 0.026970 0.026410 0.028140
Bud Site 0.046489 0.013848 0.007948 0.040508 0.018491 0.010702 0.019670 0.040942 0.020771 0.012226 0.016339 0.040864
Cell Periphery 0.000121 0.000152 0.000341 0.000322 0.000241 0.000111 0.000094 0.000156 0.000231 0.000131 0.000165 0.000186
Cytoplasm 0.199827* 0.198397* 0.107543* 0.308941* 0.244935* 0.135611* 0.231509* 0.355663* 0.241262* 0.166027* 0.196278* 0.347248*
Cytoplasmic Foci 0.109034 0.346305* 0.099118 0.119166 0.347051* 0.276165* 0.155157 0.122258 0.327670* 0.310144* 0.139231 0.121701
Eisosomes 0.000076 0.000120 0.000403 0.000077 0.000770 0.000155 0.000066 0.000075 0.000713 0.000138 0.000161 0.000075
Endoplasmic Reticulum 0.001517 0.002076 0.004175 0.003155 0.002383 0.001842 0.002647 0.002035 0.002312 0.001955 0.003081 0.002237
Endosome 0.123980 0.164067 0.234312* 0.067171 0.093771 0.242349* 0.180009 0.078227 0.096231 0.204426* 0.195442 0.076236
Golgi 0.014164 0.020462 0.002716 0.004907 0.036165 0.019977 0.002396 0.003558 0.034374 0.020212 0.002487 0.003801
Lipid Particles 0.004804 0.024499 0.021837 0.009351 0.041098 0.035813 0.018823 0.012411 0.038143 0.030332 0.019680 0.011860
Mitochondria 0.010528 0.012367 0.001590 0.000670 0.021902 0.028088 0.002963 0.003019 0.020976 0.020472 0.002572 0.002596
Mitotic Spindle 0.024955 0.009942 0.005529 0.019392 0.001841 0.006548 0.033233 0.026348 0.003723 0.008192 0.025359 0.025095
None 0.001242 0.002119 0.002097 0.002676 0.003775 0.001655 0.002016 0.003119 0.003569 0.001880 0.002039 0.003039
Nuclear Periphery 0.000872 0.001080 0.004178 0.001419 0.000294 0.000782 0.002778 0.002277 0.000341 0.000926 0.003176 0.002122
Nuclear Periphery Foci 0.001832 0.002216 0.010982 0.010360 0.000537 0.000531 0.008673 0.002557 0.000643 0.001347 0.009329 0.003962
Nucleolus 0.007096 0.002516 0.015230 0.001256 0.001968 0.001745 0.004989 0.004457 0.002386 0.002118 0.007900 0.003881
Nucleus 0.104194 0.035790 0.224970* 0.097771 0.041192 0.026117 0.083368 0.123437 0.046322 0.030803 0.123612 0.118814
Peroxisomes 0.016408 0.019208 0.018307 0.018091 0.018810 0.018343 0.020755 0.018262 0.018615 0.018762 0.020059 0.018231
Vacuole 0.311498* 0.113258 0.206635* 0.278635* 0.069140 0.155903 0.202058* 0.167650 0.088875 0.135244 0.203359* 0.187640
Vacuole Periphery 0.004329 0.005401 0.005016 0.000551 0.004626 0.009363 0.001969 0.001648 0.004602 0.007443 0.002835 0.001451

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.62 2.61 -0.37 -3.88 -3.85 6.83 0.52 -0.19 -3.53 -0.49 6.68 2.07 -0.62 -4.27 -1.90
Bud Neck -2.65 -2.46 0.07 4.17 3.39 8.22 7.49 6.84 -1.48 -1.31 8.69 7.54 7.59 -0.75 -0.35
Bud Site 2.42 3.13 0.69 -3.01 -4.32 4.18 0.56 -5.28 -8.31 -5.29 4.41 2.52 -4.86 -8.65 -6.91
Cell Periphery -1.38 -4.82 -1.16 -0.46 1.61 7.33 8.98 6.26 -1.70 -3.76 4.65 3.75 4.36 -0.53 0.80
Cytoplasm 0.21 5.04 -3.59 -5.64 -11.25 15.83 1.51 -10.99 -24.58 -10.29 12.14 5.81 -11.08 -22.53 -15.19
Cytoplasmic Foci -26.09 -0.93 0.10 29.59 1.17 10.25 29.14 37.92 25.30 5.04 2.63 31.64 37.50 39.33 4.26
Eisosomes -4.34 -4.93 -0.40 4.47 4.88 10.59 12.50 12.47 5.04 -0.55 11.03 10.16 12.41 6.80 4.69
Endoplasmic Reticulum -0.44 -4.93 -3.66 -4.09 2.21 1.95 -2.49 0.98 -1.10 3.83 1.59 -4.28 -0.02 -1.95 4.90
Endosome -5.24 -7.01 4.04 18.72 13.03 -22.51 -7.88 6.03 25.98 11.51 -22.32 -11.38 7.86 29.15 16.33
Golgi -2.90 1.46 1.57 11.58 0.49 8.20 21.52 19.36 12.14 -1.02 8.19 21.13 19.45 16.78 -0.69
Lipid Particles -14.24 -7.70 -2.29 9.87 5.79 1.99 11.26 16.12 11.00 4.29 3.95 10.24 16.25 13.92 6.38
Mitochondria -2.00 1.67 2.00 12.94 4.59 -2.84 15.19 15.46 14.11 0.56 0.16 15.56 15.75 17.31 0.69
Mitotic Spindle 1.04 1.33 -1.00 -3.01 -3.22 -3.49 -9.32 -9.78 -7.17 1.92 -4.73 -9.00 -10.15 -7.44 0.36
None -0.82 -0.70 -0.89 -0.11 -0.22 2.61 2.37 1.39 -1.85 -1.50 2.40 2.32 1.40 -1.65 -1.50
Nuclear Periphery 0.34 -5.95 -4.48 -3.92 3.83 -4.08 -11.29 -12.72 -9.12 2.46 -3.89 -13.28 -14.07 -8.44 4.03
Nuclear Periphery Foci 0.08 -4.32 -4.52 -4.54 0.18 0.23 -7.62 -8.39 -8.66 5.49 -2.59 -8.98 -8.42 -6.46 4.98
Nucleolus 0.88 -2.89 1.17 1.75 7.27 0.99 -5.26 -4.88 -6.01 1.36 0.47 -7.75 -3.74 -4.89 5.01
Nucleus 5.29 -5.47 -0.22 -9.47 6.62 6.05 -10.06 -18.08 -21.73 -4.89 6.51 -14.39 -17.58 -23.14 1.11
Peroxisomes -2.82 -1.92 0.00 3.62 2.26 0.31 0.02 1.42 1.09 1.20 -0.48 -0.18 1.83 2.29 1.79
Vacuole 12.06 6.96 1.04 -16.66 -8.12 -17.20 -22.55 -24.45 -7.33 2.47 -9.27 -19.79 -23.00 -16.67 -1.35
Vacuole Periphery -1.53 -1.14 1.36 12.50 7.03 -8.43 7.82 10.13 16.47 0.87 -6.66 5.02 10.18 19.08 4.80
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative membrane glycoprotein; has strong similarity to Vth2p and Pep1p/Vps10p; may be involved in vacuolar protein sorting
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Vth1

Vth1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Vth1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available