Standard name
Human Ortholog
Description Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.06 0.06 0.05 0.05 0.09 0 – 0 0 0.07 0.13 0.16 0.08 0.08 0.13 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.09 0.09 0.06 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.09 0.16 0.2 0.06 0.3 0.25 0.31 0.51 – 0.52 0.57 0.07 0 0.13 0.09 0.05 0.12 0 0 0 0 0 0
Nucleus 0.69 0.81 0.75 0.79 0.82 0.67 0.63 0.63 0.57 – 0.58 0.45 0.8 0.77 0.7 0.67 0.65 0.66 0.51 0.7 0.53 0.74 0.59 0.52
Nuclear Periphery 0 0 0 0 0 0 0.05 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.39 0.21 0.25 0.15 0.15 0.26 0.26 0.24 0.31 – 0.35 0.33 0.18 0.17 0.16 0.11 0.11 0.09 0.34 0.16 0.3 0.15 0.24 0.24
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.1 0.15 0.11 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.06 0.05 0.05 0 0 0 0 0.07 0.11
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 1 0 0 1 0 0 0
Bud 0 0 0 0 0 2 1 6 4 – 5 3 1 2 0 1 1 1 0 2 0 3 2 4
Bud Neck 0 0 0 0 0 0 0 0 0 – 2 2 0 0 0 0 0 0 0 0 0 0 1 1
Bud Site 1 0 2 0 1 6 3 18 16 – 14 21 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 1 1 0 0 0 0 0 0
Cytoplasm 1 3 7 16 20 17 23 42 13 – 16 15 14 34 47 35 26 39 0 1 1 1 0 3
Endoplasmic Reticulum 0 0 0 0 0 0 1 1 0 – 0 0 0 1 0 16 7 11 0 0 4 0 1 1
Endosome 4 0 3 1 4 0 2 2 0 – 0 1 3 0 1 39 28 18 7 3 6 3 9 9
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 2 1 1 0 1
Mitochondria 6 16 39 54 21 101 111 150 194 – 192 260 15 12 39 42 14 36 2 2 1 0 3 5
Nucleus 148 143 182 216 281 223 280 303 214 – 217 207 165 208 206 301 202 202 129 140 141 159 149 150
Nuclear Periphery 4 2 3 3 13 13 21 10 10 – 5 15 1 2 6 2 2 5 5 0 2 0 0 2
Nucleolus 84 37 61 42 53 86 116 116 118 – 128 150 38 45 48 50 34 29 87 32 80 32 59 69
Peroxisomes 0 0 0 0 0 0 1 0 0 – 0 1 0 0 1 0 2 0 0 0 0 0 0 0
SpindlePole 5 0 9 1 0 4 2 4 8 – 0 2 3 3 4 47 47 33 11 2 11 4 4 6
Vac/Vac Membrane 0 4 1 2 3 2 2 4 1 – 1 6 0 2 5 27 15 15 9 8 11 5 16 30
Unique Cell Count 214 177 244 273 342 334 441 480 377 371 455 206 270 294 452 309 308 254 200 267 215 253 290
Labelled Cell Count 253 205 307 335 396 454 563 656 578 580 683 240 309 357 560 379 391 254 200 267 215 253 290


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.4 6.3 5.6 5.5 6.0 5.2 5.2 5.0 4.2 – 4.2 4.1 6.1 6.2 5.4 6.2 6.7 6.4 6.8 6.9 7.5
Std Deviation (1e-4) 1.1 1.1 1.1 1.5 1.6 1.7 2.0 1.7 1.3 – 1.1 1.2 1.8 1.6 1.5 1.2 1.4 1.4 1.8 1.8 2.2
Intensity Change (Log2) – – – -0.0 0.11 -0.08 -0.1 -0.15 -0.39 – -0.39 -0.44 0.12 0.15 -0.03 0.15 0.28 0.2 0.3 0.32 0.43


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 2.3 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 1.6 1.7 1.3 1.4 3.0 0.4 – 0.9 0.3 2.0 4.1 5.0 2.6 2.7 4.1
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 3.0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 3.9 4.0 2.8
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 1.1 -3.9 4.0 2.8 4.4 0 – 0 0 -2.8 -4.4 -0.9 -2.6 -4.5 -1.5
Nucleus 1.2 2.2 -2.0 -3.0 -3.1 -4.5 – -4.1 -7.4 1.4 0.6 -1.2 -2.2 -2.3 -2.3
Nuclear Periphery 0 1.9 1.9 2.4 0 0 – 0 0 0 0 0 0 0 0
Nucleolus -2.7 -2.9 0.2 0.4 -0.2 0 – 0 0 -1.7 -2.3 -2.5 -4.8 -4.3 -4.9
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 0 -2.0 0 0 0 – 0 0 -1.5 -1.9 -1.8 3.1 4.5 3.1
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 3.6 3.1 3.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5444 3.2557 3.3545 2.5495 2.5285 3.1181 4.003 4.4011 3.6058 4.0534 3.9993 3.722 5.1294 4.8849 4.7677 4.5906 4.2241 4.6452
Actin 0.0558 0.0005 0.0142 0.0004 0.0265 0.0013 0.0265 0.0001 0.015 0.0327 0.0314 0.0007 0.0023 0 0.0167 0.0006 0.0003 0.0021
Bud 0.0005 0.0001 0.0005 0.0001 0.0002 0.0001 0.0006 0.0001 0.0005 0.0004 0.0004 0.0001 0.0006 0 0.0002 0.0001 0 0.0002
Bud Neck 0.002 0.0013 0.0026 0.0004 0.0026 0.0017 0.0024 0.0008 0.0043 0.0011 0.0011 0.0011 0.0025 0.0002 0.0023 0.0003 0.0007 0.0016
Bud Periphery 0.0009 0.0002 0.001 0.0003 0.0006 0.0003 0.0018 0.0003 0.0013 0.0011 0.0021 0.0003 0.0017 0 0.0003 0.0002 0.0001 0.0007
Bud Site 0.0047 0.0079 0.0072 0.0002 0.0008 0.0003 0.0021 0.0051 0.0064 0.0083 0.002 0.0002 0.0046 0 0.0046 0.0002 0.0002 0.0003
Cell Periphery 0.0003 0.0001 0.0004 0 0.0001 0.0001 0.0004 0.0001 0.0004 0.0022 0.0009 0 0.0004 0 0.0006 0 0 0.0001
Cytoplasm 0.0053 0.0001 0.001 0.0002 0.0008 0.0001 0.0114 0.0001 0.0032 0.0012 0.0142 0.0003 0.0019 0.0002 0.0022 0.0006 0.0002 0.0003
Cytoplasmic Foci 0.0127 0.0002 0.0059 0.0001 0.0046 0.0003 0.0222 0.0002 0.0235 0.0148 0.0067 0.0006 0.0072 0 0.0092 0.0001 0.004 0.0012
Eisosomes 0.0007 0 0.0003 0 0.0002 0 0.0004 0 0.0003 0.0011 0.0003 0 0.0001 0 0.0001 0 0 0
Endoplasmic Reticulum 0.003 0 0.0032 0.0001 0.002 0.0001 0.0073 0 0.0027 0.0009 0.0018 0.0006 0.0021 0.0001 0.003 0.0002 0.0002 0.0006
Endosome 0.023 0.0001 0.0083 0.0002 0.0154 0.0006 0.0377 0.0002 0.0132 0.0408 0.0517 0.0036 0.0138 0.0001 0.0098 0.0006 0.0064 0.0052
Golgi 0.0094 0.0001 0.0052 0 0.0075 0.0006 0.0098 0.0001 0.0074 0.0107 0.0068 0.0005 0.0077 0 0.005 0.0001 0.0011 0.0025
Lipid Particles 0.0215 0.0002 0.0151 0.0001 0.0216 0.0038 0.024 0.0002 0.0131 0.0117 0.008 0.0029 0.01 0 0.0106 0.0002 0.0306 0.0023
Mitochondria 0.0071 0.0007 0.0246 0.0006 0.0024 0.0032 0.0189 0.0003 0.0123 0.0152 0.0357 0.003 0.0076 0.0003 0.0041 0.0033 0.0003 0.0066
None 0.0061 0.0001 0.0006 0.0002 0.0013 0.0001 0.0096 0.0001 0.0016 0.0005 0.0087 0.0002 0.0037 0 0.0024 0.0006 0.0001 0.0002
Nuclear Periphery 0.0186 0.0035 0.0175 0.0185 0.0147 0.0015 0.0283 0.0079 0.005 0.0291 0.0178 0.0029 0.0106 0.0077 0.0076 0.0258 0.0262 0.0083
Nucleolus 0.0904 0.0888 0.0734 0.0439 0.2284 0.1351 0.0808 0.0691 0.0589 0.0454 0.1831 0.1197 0.0711 0.0813 0.0704 0.0691 0.1388 0.1517
Nucleus 0.6794 0.8765 0.7944 0.8907 0.6423 0.8453 0.674 0.8863 0.7827 0.7728 0.566 0.8543 0.8221 0.9024 0.8267 0.8525 0.7116 0.8063
Peroxisomes 0.0123 0.0001 0.0121 0.0001 0.002 0.001 0.0139 0.0001 0.0222 0.0016 0.0034 0.0004 0.0043 0 0.0019 0.0001 0.0008 0.0007
Punctate Nuclear 0.0413 0.019 0.0086 0.0433 0.0246 0.004 0.0209 0.0281 0.0226 0.005 0.0322 0.0079 0.0184 0.0073 0.0204 0.0446 0.0778 0.0076
Vacuole 0.0036 0.0002 0.0023 0.0003 0.0006 0.0002 0.0036 0.0005 0.0024 0.0024 0.0141 0.0004 0.0043 0.0001 0.0015 0.0003 0.0002 0.0007
Vacuole Periphery 0.0016 0.0001 0.0017 0.0003 0.0007 0.0002 0.0035 0.0003 0.001 0.0009 0.0115 0.0003 0.0028 0.0001 0.0005 0.0006 0.0003 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.4469 14.5603 11.0556 15.9944 9.5767 10.9787 16.7761 18.6017 13.7507 18.8493
Translational Efficiency 0.5651 0.5951 0.6187 0.3991 0.7718 0.7251 0.5748 0.4684 0.5527 0.4531

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
199 121 487 1243 1510 1840 345 121 1709 1961 832 1364

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 722.79 911.69 1044.88 992.44 768.59 859.71 1116.83 1062.78 763.26 862.92 1074.72 998.68
Standard Deviation 81.96 130.97 122.66 140.64 111.64 119.63 127.65 154.95 109.59 121.01 129.69 143.37
Intensity Change Log 2 — 0.334967 0.531689 0.457403 — 0.161636 0.539123 0.467557 — 0.248242 0.535525 0.462645

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000414 0.002004 0.002514 0.002763 0.000550 0.000825 0.004225 0.002147 0.000534 0.000897 0.003223 0.002708
Bud Neck 0.004109 0.008104 0.018004 0.027620 0.004295 0.006678 0.015649 0.019695 0.004273 0.006766 0.017027 0.026917
Bud Site 0.000362 0.001211 0.002848 0.006750 0.000429 0.001191 0.002921 0.008929 0.000421 0.001192 0.002878 0.006943
Cell Periphery 0.000045 0.000065 0.000086 0.000114 0.000047 0.000036 0.000087 0.000186 0.000047 0.000038 0.000086 0.000120
Cytoplasm 0.002274 0.000835 0.003078 0.008782 0.002319 0.000853 0.000509 0.004080 0.002314 0.000852 0.002013 0.008365
Cytoplasmic Foci 0.002401 0.000094 0.000237 0.006977 0.000427 0.000617 0.000188 0.002044 0.000657 0.000585 0.000217 0.006539
Eisosomes 0.000044 0.000052 0.000074 0.000042 0.000031 0.000033 0.000086 0.000050 0.000033 0.000034 0.000079 0.000043
Endoplasmic Reticulum 0.001437 0.006545 0.008335 0.005128 0.002245 0.002596 0.012079 0.006020 0.002151 0.002840 0.009887 0.005207
Endosome 0.000254 0.000235 0.000594 0.008993 0.000313 0.001387 0.000479 0.009479 0.000306 0.001316 0.000546 0.009036
Golgi 0.000363 0.000322 0.000472 0.010995 0.000241 0.000609 0.000429 0.008669 0.000255 0.000591 0.000455 0.010789
Lipid Particles 0.002883 0.000294 0.000516 0.000679 0.000365 0.000577 0.001250 0.000541 0.000658 0.000559 0.000820 0.000667
Mitochondria 0.003292 0.001578 0.001989 0.006114 0.001229 0.003224 0.002667 0.003542 0.001469 0.003122 0.002270 0.005886
Mitotic Spindle 0.007975 0.012253 0.018798 0.182725* 0.002746 0.007897 0.033343 0.195147* 0.003355 0.008166 0.024829 0.183827*
None 0.005994 0.004595 0.002289 0.006183 0.007188 0.002605 0.001704 0.006424 0.007049 0.002727 0.002047 0.006204
Nuclear Periphery 0.000546 0.000739 0.000881 0.004028 0.000834 0.000962 0.001523 0.002509 0.000801 0.000948 0.001147 0.003893
Nuclear Periphery Foci 0.004705 0.003490 0.002364 0.006368 0.003377 0.003690 0.004007 0.009263 0.003532 0.003678 0.003045 0.006625
Nucleolus 0.260293* 0.157959 0.148837 0.173109 0.219227 0.219447 0.140504 0.144253 0.224009* 0.215653 0.145382 0.170549
Nucleus 0.700476* 0.797210* 0.782299* 0.531095* 0.752901* 0.743717* 0.769538* 0.509542* 0.746796* 0.747017* 0.777008* 0.529183*
Peroxisomes 0.001817 0.001454 0.002222 0.001976 0.000887 0.001420 0.004080 0.001587 0.000995 0.001422 0.002993 0.001942
Vacuole 0.000170 0.000765 0.003204 0.006063 0.000196 0.000849 0.004309 0.034509 0.000193 0.000843 0.003662 0.008587
Vacuole Periphery 0.000147 0.000196 0.000357 0.003494 0.000154 0.000790 0.000423 0.031383 0.000153 0.000753 0.000385 0.005968

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.15 -15.41 -8.68 -1.39 2.61 -2.77 -8.38 -6.52 -5.78 1.37 -3.89 -15.04 -9.70 -7.44 3.60
Bud Neck -2.13 -10.67 -15.35 -5.01 -6.10 -4.31 -11.01 -7.39 -6.68 -1.92 -4.80 -17.84 -20.25 -18.16 -7.13
Bud Site -3.20 -14.56 -10.26 -4.96 -1.96 -2.37 -11.10 -5.62 -5.05 -2.91 -2.73 -18.15 -11.33 -8.29 -2.66
Cell Periphery -1.55 -5.82 -5.23 -1.92 1.60 1.77 -7.00 -3.71 -4.03 -1.92 1.47 -9.46 -8.54 -10.65 0.73
Cytoplasm 1.39 0.04 -1.95 -3.60 -1.86 2.76 2.43 -1.22 -2.08 -2.02 2.99 0.95 -2.28 -4.04 -2.80
Cytoplasmic Foci 1.67 1.55 0.19 -3.22 -2.94 0.49 1.93 -0.01 -0.38 -1.36 1.12 2.44 -1.52 -2.31 -3.04
Eisosomes -1.14 -6.63 -0.68 0.86 8.53 -0.38 -12.10 -4.47 -4.39 0.36 -0.33 -15.71 -7.27 -6.59 10.29
Endoplasmic Reticulum -5.22 -14.45 -12.09 1.08 6.13 -1.32 -10.67 -5.07 -4.83 1.48 -3.07 -16.93 -12.18 -9.25 7.52
Endosome -0.78 -5.73 -4.38 -4.22 -3.38 -2.47 -3.20 -2.32 -1.56 -1.88 -2.50 -5.03 -4.61 -2.69 -3.66
Golgi 0.44 -2.84 -3.09 -3.15 -2.78 -2.67 -8.35 -1.94 -1.68 -1.65 -2.57 -10.91 -3.45 -3.09 -3.00
Lipid Particles 1.44 1.18 1.37 -1.14 2.67 0.30 -1.00 -0.28 -0.76 0.89 0.96 0.07 1.39 0.67 2.66
Mitochondria 1.10 0.52 -1.60 -8.32 -6.81 -2.54 -8.01 -5.04 -1.37 -2.18 -2.21 -6.08 -9.10 -2.80 -6.53
Mitotic Spindle -0.89 -3.53 -17.40 -11.45 -14.52 -3.23 -6.06 -7.46 -7.27 -5.42 -3.08 -8.05 -21.64 -20.77 -14.77
None 1.41 5.86 1.71 -0.62 -6.08 5.39 5.84 0.39 -2.05 -2.23 5.77 6.42 2.13 -5.42 -6.72
Nuclear Periphery -1.22 -5.98 -14.45 -4.62 -11.59 -0.37 -2.56 -3.68 -3.62 -2.52 -0.64 -2.81 -11.56 -11.84 -11.34
Nuclear Periphery Foci 0.27 0.38 -0.00 -0.32 -0.53 0.35 -0.62 -1.46 -1.55 -1.19 0.45 -0.37 -1.18 -1.65 -0.70
Nucleolus 5.27 5.90 5.11 -1.81 -1.90 -0.39 5.94 3.62 3.81 0.03 1.19 7.62 5.04 4.16 -2.72
Nucleus -3.80 -2.47 6.95 11.20 13.86 1.25 2.06 7.87 7.57 6.40 -0.11 1.59 19.81 20.28 15.73
Peroxisomes 0.41 -1.83 0.40 -0.05 5.37 -0.75 -4.29 -3.03 -1.85 1.88 -0.61 -6.47 -1.78 -0.45 5.41
Vacuole -3.46 -8.00 -6.25 -4.99 -0.48 -2.87 -4.78 -3.36 -3.27 -2.18 -3.22 -8.07 -6.92 -6.26 -0.80
Vacuole Periphery -2.25 -8.72 -2.89 -2.69 -2.11 -2.37 -10.79 -1.70 -1.58 -1.63 -2.40 -15.57 -3.12 -1.99 -2.57
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
Localization
Cell Percentages nucleus (92%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Dal81

Dal81


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Dal81-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available