Standard name
Human Ortholog
Description Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.05 0.07 0.13 0.1 0.1 0.11 0.11 0.19 0.19 0.2 0.21 0 0 0 0.25 0.16 0.1 0 0 0.05 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.08 0.06 0.05 0.07 0.08 0.07 0.09 0.13 0.13 0.18 0.06 0.09 0.13 0.31 0.24 0.33 0 0 0 0 0.05 0.05
Cytoplasm 0 0.11 0 0.05 0.06 0.07 0.07 0 0.06 0 0 0.07 0.07 0.08 0.08 0.31 0.32 0.19 0 0 0 0 0 0
Endoplasmic Reticulum 0.95 0.92 0.91 0.77 0.73 0.79 0.79 0.85 0.68 0.75 0.67 0.63 0.9 0.88 0.86 0 0 0 0.97 0.91 0.89 0.84 0.81 0.86
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.05 0 0.2 0.37 0.35 0.11 0.09 0.09 0.11 0.08 0.08 0.16 0.06 0 0 0.31 0.38 0.43 0 0 0 0 0 0
Mitochondria 0 0 0 0.12 0.06 0.11 0.13 0.12 0.25 0.21 0.31 0.23 0 0 0 0.19 0.08 0.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 14 34 40 39 50 69 73 75 86 92 99 9 18 12 4 6 2 0 3 22 10 20 17
Bud 2 3 1 1 1 2 2 6 4 3 6 8 2 0 1 0 1 0 0 1 1 0 3 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 8 8 40 20 20 37 48 50 38 60 58 83 12 39 52 5 9 7 1 1 8 11 23 26
Cytoplasm 5 28 13 17 22 36 43 18 23 20 20 31 15 31 30 5 12 4 0 3 0 2 6 5
Endoplasmic Reticulum 181 240 448 245 274 392 481 582 276 346 306 291 184 364 334 0 0 0 186 243 438 274 401 482
Endosome 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 2 2 0 2 1
Golgi 10 4 101 119 131 53 53 60 46 39 35 72 12 7 3 5 14 9 0 2 7 13 20 8
Mitochondria 1 0 13 38 21 53 80 84 101 96 142 106 0 0 0 3 3 2 1 3 4 6 8 6
Nucleus 0 0 0 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0
Nuclear Periphery 0 0 12 4 2 8 6 19 15 9 20 10 3 2 0 0 0 0 0 0 0 0 1 1
Nucleolus 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 3 0 2 0 12 14 9 0 3 3 6 9 0 4 5 0 0 0 0 3 0 1 7 4
Unique Cell Count 190 261 493 319 376 494 608 683 403 464 457 463 204 412 387 16 37 21 192 267 490 326 497 563
Labelled Cell Count 217 297 664 484 523 647 791 893 582 662 686 709 237 465 437 22 45 24 192 267 490 326 497 563


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 30.1 30.1 28.5 27.8 27.8 25.1 23.6 22.9 21.4 21.4 21.3 21.8 24.7 26.5 26.6 25.1 26.0 36.1 26.5 26.9 29.7
Std Deviation (1e-4) 4.5 5.7 4.6 4.5 4.6 3.8 3.8 4.2 3.9 3.9 3.8 4.2 4.8 5.2 4.4 6.6 8.7 6.8 5.5 5.7 5.7
Intensity Change (Log2) – – – -0.04 -0.04 -0.19 -0.28 -0.32 -0.42 -0.41 -0.42 -0.39 -0.21 -0.11 -0.1 -0.19 -0.14 0.34 -0.11 -0.08 0.06

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 2.7 1.8 1.8 2.5 2.2 5.3 5.4 6.0 6.5 -1.2 -1.6 -2.5 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.0 -1.6 -0.4 -0.1 -0.5 0.7 2.4 2.3 4.5 -1.0 0.7 2.6 0 0 0
Cytoplasm 2.0 2.4 3.4 3.3 0 2.3 1.4 1.5 3.0 2.9 3.4 3.5 0 0 0
Endoplasmic Reticulum -5.5 -7.0 -5.1 -5.3 -2.9 -8.5 -6.7 -9.1 -10.3 -0.3 -1.2 -2.1 -11.0 -14.7 -12.2
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 5.3 4.7 -4.2 -5.6 -5.8 -3.6 -5.3 -5.6 -2.0 -4.8 -8.7 -9.0 0 2.5 0
Mitochondria 5.3 2.2 5.1 6.2 5.9 10.0 8.8 11.9 9.5 0 -3.3 -3.2 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery -1.2 -2.2 -0.9 -1.9 0.4 1.1 -0.5 1.7 -0.3 0 -2.4 -3.1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 3.2 3.0 0 0 0 0 0 2.2 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 24.4976 27.9048 25.6518 24.2243 21.8504 26.9929 29.8486 33.0831 31.4956 29.3488 29.3854 30.5534 30.8113 32.7315 30.0832 31.2862 29.8429 30.7795
Actin 0.0095 0.0023 0.0175 0.0003 0.0032 0.0019 0.0048 0.0004 0.0054 0.0014 0.0278 0.0023 0.0143 0.0017 0.0023 0.0002 0.006 0.0004
Bud 0.0005 0.0003 0.0005 0 0.0001 0 0.0001 0 0 0 0.0001 0 0.0003 0 0 0 0 0
Bud Neck 0.0006 0.0004 0.0006 0.0001 0.0003 0.0003 0.0001 0.0002 0.0003 0 0.0001 0.0001 0.0004 0.0003 0.0003 0.0002 0.0003 0.0002
Bud Periphery 0.001 0.0008 0.001 0.0001 0.0006 0.0001 0.0003 0 0.0001 0.0001 0.0003 0 0.001 0.0001 0.0001 0 0.0003 0
Bud Site 0.001 0.0005 0.0025 0.0001 0.0001 0 0.0006 0 0.0003 0.0001 0.0001 0 0.0027 0 0.0001 0 0.0001 0
Cell Periphery 0.0058 0.0178 0.0135 0.0016 0.0127 0.0022 0.0049 0.0077 0.0064 0.0052 0.001 0.0017 0.0047 0.0062 0.0107 0.0072 0.0036 0.0011
Cytoplasm 0.0269 0.0186 0.012 0.0016 0.0049 0.0108 0.0022 0.0029 0.0021 0.0004 0.0005 0.0004 0.0017 0.004 0.0014 0.0004 0.0009 0.0005
Cytoplasmic Foci 0.006 0.0013 0.0057 0.0048 0.004 0.0006 0.0071 0.0006 0.0013 0.0002 0.0003 0.0004 0.01 0.0011 0.0096 0.0001 0.0043 0.0007
Eisosomes 0.0004 0.0012 0.0017 0.0001 0.0003 0.0002 0.0006 0.003 0.0007 0.0008 0.0002 0.0005 0.0016 0.0006 0.0003 0.0012 0.001 0.0001
Endoplasmic Reticulum 0.833 0.9224 0.8654 0.9492 0.815 0.9525 0.9264 0.9639 0.9654 0.9491 0.9523 0.9792 0.839 0.9114 0.9473 0.9558 0.8736 0.9574
Endosome 0.0169 0.0019 0.0091 0.0109 0.022 0.0032 0.0053 0.0009 0.0018 0.0006 0.0021 0.001 0.0051 0.0036 0.0021 0.0009 0.0023 0.0036
Golgi 0.0074 0.0079 0.0084 0.0082 0.0179 0.0047 0.0058 0.0077 0.0029 0.0017 0.008 0.0052 0.0052 0.0476 0.0025 0.0217 0.018 0.0067
Lipid Particles 0.0121 0.0122 0.0138 0.0098 0.0216 0.0018 0.005 0.0055 0.0018 0.0043 0.0012 0.0018 0.0077 0.0068 0.0033 0.0016 0.0021 0.0034
Mitochondria 0.0088 0.0011 0.0148 0.0015 0.0065 0.0064 0.0074 0.0009 0.003 0.0248 0.0013 0.0007 0.0167 0.0002 0.0001 0.0001 0.0006 0.0022
None 0.0025 0.0002 0.0059 0.0011 0.0009 0.0001 0.0011 0.0002 0.0001 0.0002 0.0001 0.0001 0.0032 0.0001 0.0008 0 0.0002 0
Nuclear Periphery 0.0406 0.0065 0.0127 0.0046 0.0407 0.0121 0.0196 0.0039 0.004 0.0075 0.0032 0.0042 0.0661 0.0132 0.0125 0.0089 0.006 0.0212
Nucleolus 0.0008 0.0001 0.0006 0.0003 0.0003 0 0.0001 0.0001 0 0.0001 0 0 0.0017 0 0 0 0 0
Nucleus 0.0045 0.0005 0.0018 0.0003 0.0146 0.0007 0.0004 0.0001 0.0001 0.0002 0.0001 0.0001 0.0029 0.0003 0.0002 0.0001 0.0001 0.0002
Peroxisomes 0.0021 0 0.003 0.0005 0.0223 0 0.0015 0 0.0007 0.0006 0.0003 0.0009 0.0022 0 0.0009 0 0.0786 0.0001
Punctate Nuclear 0.003 0.0001 0.0022 0.0004 0.0011 0.0001 0.0033 0 0 0 0.0002 0.0001 0.004 0 0.003 0 0.0003 0
Vacuole 0.0107 0.0036 0.0045 0.0032 0.0046 0.0012 0.0019 0.0014 0.0025 0.0016 0.0005 0.001 0.0038 0.002 0.0018 0.0009 0.0007 0.0007
Vacuole Periphery 0.0059 0.0005 0.0027 0.0011 0.0065 0.001 0.0016 0.0008 0.0011 0.0012 0.0002 0.0004 0.0057 0.0008 0.0005 0.0006 0.0009 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 212.816 173.7015 146.7959 169.9639 160.9564 174.1659 182.5988 167.2232 150.1472 185.662
Translational Efficiency 0.7751 0.8686 0.8879 0.8117 0.8551 0.9266 0.7654 0.6598 0.7157 0.6635

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
91 1498 357 961 1890 1933 183 1619 1981 3431 540 2580

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2195.37 2176.98 3000.97 2823.54 1632.26 1997.66 2934.73 2714.28 1658.13 2075.95 2978.52 2754.98
Standard Deviation 357.18 395.59 430.84 511.68 302.07 335.45 369.92 440.11 326.82 373.67 412.40 471.02
Intensity Change Log 2 — -0.012136 0.450965 0.363041 — 0.291440 0.846357 0.733699 — 0.125200 0.632967 0.532867

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000628 0.001004 0.000786 0.001050 0.000857 0.000799 0.000102 0.000673 0.000846 0.000889 0.000554 0.000814
Bud Neck 0.003296 0.000224 0.005556 0.001261 0.000129 0.000157 0.000563 0.000453 0.000275 0.000187 0.003864 0.000754
Bud Site 0.006846 0.000551 0.001031 0.002639 0.001070 0.000977 0.000232 0.000980 0.001336 0.000791 0.000760 0.001598
Cell Periphery 0.008868 0.002256 0.010033 0.017090 0.003901 0.002350 0.007862 0.007090 0.004130 0.002309 0.009297 0.010815
Cytoplasm 0.001005 0.000175 0.000168 0.000292 0.000603 0.000325 0.000009 0.000297 0.000622 0.000260 0.000114 0.000295
Cytoplasmic Foci 0.009990 0.000412 0.000069 0.000848 0.001912 0.001276 0.000025 0.000230 0.002283 0.000899 0.000054 0.000461
Eisosomes 0.000154 0.000622 0.001342 0.000882 0.000493 0.000458 0.001479 0.000304 0.000478 0.000529 0.001389 0.000519
Endoplasmic Reticulum 0.856179 0.970039 0.895364 0.919645 0.964944 0.967759 0.962488 0.949098 0.959948 0.968754 0.918112 0.938127
Endosome 0.019588 0.004918 0.008380 0.005759 0.005456 0.006554 0.003312 0.005896 0.006105 0.005840 0.006662 0.005845
Golgi 0.033028 0.010419 0.008710 0.014888 0.010349 0.008484 0.008427 0.009949 0.011391 0.009329 0.008614 0.011788
Lipid Particles 0.022486 0.003936 0.011778 0.013466 0.004604 0.007341 0.003579 0.011852 0.005426 0.005854 0.008999 0.012453
Mitochondria 0.001275 0.000634 0.000494 0.000930 0.000896 0.000232 0.000163 0.000229 0.000913 0.000407 0.000382 0.000490
Mitotic Spindle 0.000302 0.000021 0.000069 0.000373 0.000102 0.000028 0.000017 0.000070 0.000112 0.000025 0.000052 0.000183
None 0.000040 0.000157 0.000036 0.000284 0.000689 0.000227 0.000023 0.000641 0.000660 0.000196 0.000031 0.000508
Nuclear Periphery 0.001766 0.000451 0.021802 0.003534 0.000400 0.000265 0.003939 0.001658 0.000462 0.000346 0.015748 0.002357
Nuclear Periphery Foci 0.006126 0.001092 0.011499 0.002782 0.000605 0.000786 0.001222 0.002539 0.000858 0.000920 0.008016 0.002630
Nucleolus 0.000015 0.000003 0.000023 0.000016 0.000006 0.000002 0.000006 0.000005 0.000006 0.000002 0.000017 0.000009
Nucleus 0.000068 0.000041 0.000104 0.000109 0.000049 0.000020 0.000021 0.000088 0.000050 0.000029 0.000076 0.000096
Peroxisomes 0.001228 0.000046 0.000003 0.000034 0.000270 0.000214 0.000002 0.000028 0.000314 0.000140 0.000003 0.000030
Vacuole 0.016692 0.001941 0.018669 0.009579 0.001119 0.001073 0.005059 0.006341 0.001835 0.001452 0.014057 0.007547
Vacuole Periphery 0.010419 0.001056 0.004083 0.004539 0.001544 0.000674 0.001471 0.001580 0.001951 0.000841 0.003198 0.002682

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.89 -0.37 -0.82 -0.22 -0.52 0.19 2.80 -0.01 -0.18 -2.27 -0.14 0.80 -0.32 -0.24 -1.06
Bud Neck 2.26 -1.36 1.40 -3.41 3.98 -0.71 -3.85 -3.42 -3.14 0.03 1.19 -5.26 -3.63 -4.53 4.36
Bud Site 2.23 2.05 1.38 -2.79 -2.08 0.21 2.55 -0.24 -0.42 -2.74 1.43 1.49 -0.94 -2.40 -2.47
Cell Periphery 3.18 -0.49 -2.98 -7.99 -3.07 3.27 -2.52 -4.20 -6.68 0.41 4.15 -4.70 -7.53 -10.28 -1.16
Cytoplasm 1.10 1.09 0.92 -1.27 -1.03 0.88 1.87 0.83 -0.13 -4.25 1.18 1.60 0.96 -0.96 -2.56
Cytoplasmic Foci 1.87 1.94 1.78 -1.30 -2.42 1.32 4.84 4.28 3.73 -4.54 2.94 5.05 3.97 2.15 -3.30
Eisosomes -1.97 -3.46 -3.49 -0.86 1.17 0.14 -1.78 1.46 0.66 2.15 -0.26 -2.94 -0.30 0.05 2.90
Endoplasmic Reticulum -3.91 -1.24 -2.13 8.65 -2.43 -0.87 0.54 4.45 5.02 2.80 -2.89 6.48 6.07 9.52 -2.90
Endosome 3.06 2.31 2.87 -1.38 3.32 -1.99 4.45 -0.91 0.81 -4.31 0.52 -1.10 0.31 -0.18 1.40
Golgi 1.91 2.05 1.53 -2.77 -3.31 1.57 1.62 0.32 -1.26 -1.30 1.82 2.12 -0.35 -2.61 -2.78
Lipid Particles 3.05 1.53 1.42 -5.12 -0.39 -2.87 0.45 -5.49 -3.06 -3.58 -0.56 -1.85 -6.26 -5.72 -1.41
Mitochondria 0.80 1.12 0.38 -0.63 -1.28 2.33 2.83 2.08 -0.50 -1.25 1.64 2.09 1.22 -0.63 -1.08
Mitotic Spindle 2.65 2.19 -0.45 -2.63 -2.27 2.08 2.41 0.44 -1.77 -2.14 2.53 1.71 -1.27 -3.09 -2.58
None -2.00 0.24 -2.64 -1.23 -2.70 1.78 2.60 0.09 -1.14 -1.70 1.87 2.56 0.42 -1.36 -2.07
Nuclear Periphery 1.75 -6.69 -2.15 -11.93 6.30 2.64 -7.78 -8.53 -9.19 4.73 1.92 -7.82 -13.69 -14.69 6.84
Nuclear Periphery Foci 2.26 -1.94 1.47 -2.44 4.70 -0.74 -2.57 -3.46 -2.87 -2.27 -0.37 -6.02 -4.18 -3.67 4.28
Nucleolus 1.71 -1.00 -0.23 -3.07 0.99 3.62 0.10 0.12 -3.07 0.03 3.36 -2.90 -1.56 -4.09 1.89
Nucleus 0.74 -1.25 -1.51 -2.07 -0.15 3.55 3.54 -1.65 -2.22 -2.21 1.46 -1.54 -2.27 -2.75 -1.25
Peroxisomes 1.07 1.11 1.08 0.46 -3.01 0.59 3.75 3.35 2.84 -2.68 1.87 3.66 3.33 2.86 -3.79
Vacuole 3.38 -0.50 1.55 -6.52 3.36 0.10 -5.20 -6.24 -6.26 -1.63 0.84 -7.07 -8.04 -8.80 3.41
Vacuole Periphery 1.39 0.94 0.86 -4.07 -0.43 2.85 0.22 -0.23 -3.45 -0.49 2.64 -1.92 -1.50 -5.12 0.76
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins
Localization
Cell Percentages ER (98%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Ost1

Ost1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ost1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available