Standard name
Human Ortholog
Description UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline; UBX6 has a paralog, UBX7, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0
Bud Neck – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm – 0 0.05 0.06 0.07 0 0 0 0 0 0.05 0 0.13 0.21 0.31 0.17 0.09 0.1 0 0 0 0 0 0
Endoplasmic Reticulum – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome – 0.06 0.29 0.17 0.2 0.13 0.1 0.14 0.05 0.05 0 0.05 0.05 0 0 0.24 0.23 0.21 0.09 0.09 0.16 0.13 0.19 0.27
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria – 0.11 0.13 0.22 0.08 0.18 0.18 0.11 0.11 0.19 0.22 0.21 0 0 0 0 0 0 0.08 0.05 0 0 0 0
Nucleus – 0.09 0.06 0.1 0.11 0.2 0.2 0.22 0.25 0.23 0.26 0.21 0.16 0.26 0.28 0 0.06 0 0 0.06 0 0.07 0.05 0.05
Nuclear Periphery – 0.11 0.07 0.13 0.08 0.17 0.22 0.2 0.28 0.18 0.19 0.18 0.07 0 0 0 0 0 0.63 0.36 0.38 0.21 0.15 0.17
Nucleolus – 0.16 0.23 0.29 0.35 0.28 0.28 0.29 0.33 0.36 0.39 0.35 0 0 0 0.17 0.16 0.17 0 0 0 0 0 0
Peroxisomes – 0 0 0 0.07 0 0.07 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole – 0.05 0.29 0.25 0.38 0.21 0.19 0.25 0.19 0.21 0.12 0.17 0 0 0 0.18 0.13 0.14 0 0.1 0.27 0.31 0.36 0.26
Vac/Vac Membrane – 0.67 0.29 0.16 0.12 0.15 0.07 0.08 0.07 0.07 0.08 0.12 0.65 0.53 0.41 0.49 0.58 0.56 0 0.18 0 0.09 0.06 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – 0 0 0 0 0 0 0 0 0 0 0 1 1 0 2 0 2 1 0 2 1 0 0
Bud – 0 8 3 3 4 20 14 6 15 6 9 0 0 0 2 1 1 1 3 6 2 5 6
Bud Neck – 0 0 0 0 0 2 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site – 0 2 2 3 5 17 13 10 20 11 15 1 0 0 0 1 0 – – – – – –
Cell Periphery – 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 0 0 0 0 0 0
Cytoplasm – 2 12 13 25 14 21 15 15 17 13 9 16 44 77 35 15 14 0 4 4 1 7 7
Endoplasmic Reticulum – 0 0 0 0 1 0 0 0 1 0 2 3 9 11 4 3 6 1 2 6 0 1 2
Endosome – 4 65 40 68 41 56 86 22 31 5 19 6 5 4 48 37 31 3 9 40 5 39 59
Golgi – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 0 0 2 0 0 3
Mitochondria – 7 28 51 26 56 102 66 44 111 63 80 1 1 0 8 7 5 3 4 5 1 7 5
Nucleus – 6 14 24 39 62 119 136 102 136 76 78 20 54 69 7 9 5 1 6 5 3 11 10
Nuclear Periphery – 7 16 31 26 54 130 123 113 110 54 69 8 6 7 2 2 1 27 37 98 9 30 36
Nucleolus – 10 52 66 121 88 161 178 135 216 111 131 2 1 1 34 26 25 0 1 2 0 7 3
Peroxisomes – 0 5 7 25 13 40 40 5 11 2 2 0 0 0 4 0 1 0 0 4 0 1 1
SpindlePole – 3 65 58 130 65 112 158 78 127 35 66 1 2 0 37 20 21 1 10 69 13 73 56
Vac/Vac Membrane – 43 64 36 40 48 38 51 27 39 23 47 79 110 101 99 92 82 0 18 9 3 13 20
Unique Cell Count 64 223 230 346 316 582 621 409 599 287 379 122 209 247 202 159 146 43 104 261 45 206 219
Labelled Cell Count 82 331 331 506 451 818 882 557 835 400 527 138 235 270 282 215 198 43 104 261 45 206 219


Nuclear Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – 6.8 6.6 6.3 7.3 6.4 6.7 6.9 7.1 6.8 6.6 6.8 7.6 7.7 7.4 10.3 9.8 10.2 – 8.0 8.4
Std Deviation (1e-4) – 1.5 1.2 1.5 2.0 1.7 1.7 1.8 1.9 1.8 2.0 2.0 1.3 1.1 1.2 3.0 2.5 2.8 – 1.4 1.4
Intensity Change (Log2) – – – -0.05 0.15 -0.04 0.03 0.07 0.1 0.06 -0.0 0.06 0.21 0.24 0.18 0.65 0.58 0.64 – 0.28 0.35

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud -1.6 0 0 -0.1 -1.1 0 -0.8 -1.0 -0.9 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 1.7 0 0 1.9 2.1 2.2 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 0.9 -0.5 -1.1 -2.2 -1.0 -1.8 -0.4 -1.9 2.5 4.8 7.1 3.9 1.5 1.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 3.2 0 0 0
Endosome -3.0 -2.6 -4.7 -6.9 -5.1 -8.3 -9.5 -8.9 -8.3 -5.3 -7.5 -8.4 -1.3 -1.3 -1.7
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.7 -2.0 1.6 1.7 -0.8 -0.7 2.0 2.7 2.6 -3.8 -5.0 -5.7 -3.2 -2.7 -3.0
Nucleus 1.6 2.0 4.4 4.8 5.2 5.8 5.4 5.9 4.7 3.0 5.6 6.1 -1.3 -0.3 -1.2
Nuclear Periphery 2.2 0.2 3.4 5.0 4.4 6.1 4.0 3.8 3.8 -0.2 -2.0 -2.2 -3.2 -2.7 -2.9
Nucleolus 1.3 2.9 1.2 1.3 1.5 2.6 3.5 3.7 2.9 -5.3 -7.2 -7.8 -1.7 -1.7 -1.4
Peroxisomes 0.5 2.6 1.2 2.6 2.4 0 0 0 0 0 0 0 0 0 0
SpindlePole -0.9 2.1 -2.3 -3.0 -1.1 -2.9 -2.4 -4.8 -3.4 -6.4 -8.1 -9.1 -2.6 -3.8 -3.3
Vacuole -3.3 -5.2 -3.8 -8.5 -7.6 -7.6 -8.5 -6.2 -5.0 6.5 5.1 2.8 4.3 5.7 5.3

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.412 3.3022 3.465 3.6443 2.828 3.0606 1.2463 1.8837 1.2366 1.1698 0.9003 1.5671 0.6235 1.5906 0.8364 1.3093 0.2552 0.5808
Actin 0.0014 0.0006 0.0003 0.0093 0.0847 0.0017 0.0249 0.0027 0.0074 0.0209 0.0686 0.0013 0.0105 0.001 0.0003 0.0294 0.0199 0.0076
Bud 0.0001 0.0001 0 0.0002 0.0002 0.0001 0.0004 0.0001 0.0005 0.0005 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0003 0.0001
Bud Neck 0.0068 0.0011 0.0002 0.0006 0.0625 0.001 0.0056 0.0006 0.0005 0.0024 0.0004 0.0014 0.0004 0.0002 0.0001 0.0127 0.001 0.0013
Bud Periphery 0.0001 0.0001 0 0.0004 0.0004 0.0002 0.0004 0.0002 0.0007 0.0007 0.0004 0.0001 0.0002 0.0001 0 0.0001 0.0006 0.0001
Bud Site 0.0006 0.0017 0.0002 0.0004 0.0013 0.0001 0.0059 0.0016 0.0022 0.0021 0.0006 0.0001 0.0005 0.0011 0.0001 0.0004 0.0009 0.0002
Cell Periphery 0.0001 0 0 0 0.0002 0.0001 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0 0 0.0001 0.0001
Cytoplasm 0.0107 0.0032 0.0065 0.0052 0.0075 0.0101 0.0074 0.0179 0.0253 0.0084 0.0426 0.0324 0.0052 0.0076 0.002 0.0041 0.0005 0.004
Cytoplasmic Foci 0.0371 0.0094 0.0117 0.0065 0.0244 0.0098 0.0403 0.0271 0.0303 0.0231 0.0386 0.0129 0.0252 0.0349 0.0227 0.0265 0.033 0.0153
Eisosomes 0 0 0 0.0001 0.0006 0 0.0003 0 0.0001 0.0002 0.0002 0 0.0003 0 0 0.0002 0.0002 0
Endoplasmic Reticulum 0.0061 0.0077 0.0067 0.003 0.0043 0.0052 0.0175 0.0103 0.0102 0.0095 0.0107 0.0074 0.0069 0.0068 0.0043 0.0021 0.0014 0.0099
Endosome 0.018 0.0077 0.0061 0.0138 0.0088 0.0062 0.0326 0.0082 0.0179 0.0401 0.0513 0.0134 0.0242 0.006 0.0042 0.0067 0.0164 0.0099
Golgi 0.0023 0.0012 0.0011 0.0022 0.0045 0.0018 0.0127 0.0037 0.0069 0.0116 0.0152 0.0021 0.0048 0.0017 0.0014 0.0037 0.0076 0.0027
Lipid Particles 0.0322 0.0259 0.0235 0.0058 0.0208 0.0277 0.0844 0.0614 0.0402 0.0383 0.0917 0.0415 0.0392 0.0463 0.0282 0.0131 0.0206 0.0452
Mitochondria 0.0005 0.0004 0.0002 0.0051 0.0009 0.0024 0.005 0.0027 0.0075 0.0077 0.0097 0.0007 0.0022 0.0004 0.0001 0.0004 0.0032 0.0003
None 0.0263 0.0008 0.0061 0.0025 0.0076 0.008 0.0026 0.0009 0.0019 0.003 0.0036 0.0069 0.0028 0.001 0.0003 0.0009 0.0009 0.0007
Nuclear Periphery 0.3649 0.3481 0.2 0.1925 0.1919 0.3992 0.2256 0.1857 0.2018 0.15 0.1782 0.3477 0.3597 0.2205 0.2001 0.0434 0.0144 0.337
Nucleolus 0.008 0.0345 0.0244 0.0038 0.0353 0.0223 0.0112 0.0316 0.0079 0.0445 0.0013 0.0114 0.0046 0.0351 0.0098 0.0258 0.0611 0.016
Nucleus 0.0185 0.0613 0.0293 0.0479 0.0329 0.0563 0.0281 0.0467 0.0463 0.0471 0.0345 0.0666 0.0392 0.0414 0.0244 0.0055 0.005 0.0462
Peroxisomes 0.0015 0.0006 0.0004 0.0014 0.0025 0.001 0.0124 0.0014 0.0035 0.0041 0.0031 0.0014 0.0016 0.0009 0.0006 0.0026 0.0014 0.0013
Punctate Nuclear 0.4583 0.4902 0.6804 0.6946 0.5051 0.4426 0.4768 0.594 0.5816 0.5776 0.4416 0.4469 0.4661 0.5907 0.6987 0.8217 0.81 0.4985
Vacuole 0.0017 0.0016 0.0009 0.0018 0.0012 0.0013 0.0023 0.001 0.0039 0.0031 0.0039 0.0019 0.0017 0.0011 0.0004 0.0003 0.0007 0.0012
Vacuole Periphery 0.0046 0.004 0.002 0.0028 0.0028 0.003 0.0035 0.0021 0.0034 0.0048 0.0035 0.0036 0.0044 0.0031 0.0022 0.0004 0.0008 0.0024

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.1174 8.2819 5.531 9.6967 8.4083 5.5556 8.1645 14.9772 10.1781 10.2943
Translational Efficiency 0.6354 0.7256 1.0574 0.8682 0.9283 1.8956 0.8244 0.5656 1.01 0.7701

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1118 183 2497 248 1146 1169 819 286 2264 1352 3316 534

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 761.54 913.17 818.54 903.33 765.18 821.89 795.05 922.99 763.38 834.25 812.74 913.86
Standard Deviation 101.45 125.30 125.90 134.41 110.58 122.35 110.66 110.17 106.18 126.67 122.73 122.42
Intensity Change Log 2 — 0.261964 0.104133 0.246333 — 0.103146 0.055246 0.270516 — 0.184550 0.079839 0.258504

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000200 0.000404 0.000282 0.005418 0.000377 0.000233 0.000417 0.000986 0.000289 0.000256 0.000315 0.003044
Bud Neck 0.002332 0.001733 0.009565 0.013418 0.002282 0.001903 0.003480 0.008234 0.002307 0.001880 0.008062 0.010642
Bud Site 0.001471 0.000964 0.005399 0.031863 0.001296 0.001254 0.005012 0.024827 0.001382 0.001215 0.005303 0.028095
Cell Periphery 0.000134 0.000077 0.000088 0.000255 0.000151 0.000118 0.000111 0.000158 0.000142 0.000113 0.000094 0.000203
Cytoplasm 0.036741 0.008018 0.139384 0.248087 0.032701 0.031553 0.117286 0.177855 0.034696 0.028368 0.133926 0.210472
Cytoplasmic Foci 0.020355 0.011540 0.006486 0.030046 0.013428 0.020533 0.016919 0.044622 0.016849 0.019315 0.009063 0.037853
Eisosomes 0.000037 0.000023 0.000019 0.000080 0.000029 0.000033 0.000040 0.000079 0.000033 0.000031 0.000024 0.000079
Endoplasmic Reticulum 0.014206 0.013775 0.019924 0.024279 0.012916 0.010238 0.031773 0.021463 0.013553 0.010717 0.022850 0.022771
Endosome 0.008345 0.005452 0.007879 0.017796 0.007468 0.009505 0.014089 0.028636 0.007901 0.008957 0.009413 0.023602
Golgi 0.001717 0.001583 0.000383 0.021336 0.000811 0.002264 0.002211 0.006423 0.001258 0.002172 0.000834 0.013348
Lipid Particles 0.074108 0.036489 0.005867 0.012443 0.019946 0.045315 0.018612 0.017026 0.046692 0.044120 0.009015 0.014898
Mitochondria 0.006119 0.001708 0.005947 0.001376 0.002106 0.005091 0.002761 0.006441 0.004088 0.004633 0.005160 0.004089
Mitotic Spindle 0.051507 0.124224 0.079096 0.140732 0.048940 0.074905 0.049727 0.146336 0.050208 0.081580 0.071842 0.143733
None 0.003912 0.001125 0.003975 0.005044 0.006298 0.004358 0.003395 0.003989 0.005120 0.003920 0.003831 0.004479
Nuclear Periphery 0.110212 0.053762 0.274409 0.012943 0.052584 0.087040 0.177132 0.030328 0.081042 0.082535 0.250383 0.022254
Nuclear Periphery Foci 0.598316 0.702225 0.218983 0.080436 0.676047 0.613952 0.384987 0.237912 0.637662 0.625900 0.259983 0.164777
Nucleolus 0.026739 0.011283 0.011680 0.002435 0.037967 0.034538 0.010704 0.004489 0.032422 0.031390 0.011439 0.003535
Nucleus 0.037828 0.013037 0.191153 0.161127 0.080674 0.048383 0.132897 0.106807 0.059516 0.043599 0.176764 0.132034
Peroxisomes 0.002458 0.001792 0.000469 0.008529 0.001133 0.002306 0.000973 0.003617 0.001787 0.002236 0.000593 0.005898
Vacuole 0.002637 0.005728 0.018077 0.180218 0.002188 0.004591 0.026065 0.128991 0.002410 0.004745 0.020050 0.152782
Vacuole Periphery 0.000627 0.005057 0.000937 0.002139 0.000659 0.001888 0.001410 0.000784 0.000643 0.002317 0.001054 0.001413

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.87 -3.79 -1.85 -1.69 -1.74 2.49 -1.40 -4.44 -5.82 -2.50 0.70 -2.48 -2.31 -2.35 -2.14
Bud Neck 1.16 -10.01 -5.77 -6.03 -1.66 0.93 -3.73 -5.40 -5.61 -3.91 1.22 -10.90 -7.90 -8.16 -2.57
Bud Site 1.31 -4.60 -4.77 -4.87 -4.01 -0.20 -3.02 -4.36 -4.33 -2.94 0.23 -5.66 -6.42 -6.44 -5.03
Cell Periphery 2.78 2.89 -3.48 -6.37 -7.28 1.52 2.15 -0.96 -2.36 -3.13 1.78 4.41 -3.28 -4.76 -8.39
Cytoplasm 5.16 -18.96 -10.23 -11.94 -3.52 0.06 -11.97 -11.14 -11.13 -3.58 1.53 -23.81 -15.08 -15.45 -4.69
Cytoplasmic Foci 1.45 7.16 -0.29 -1.49 -4.79 -2.46 -1.55 -4.42 -2.78 -3.62 -0.85 6.11 -3.63 -2.62 -6.91
Eisosomes 2.38 5.97 -7.99 -8.46 -11.13 -1.27 -3.85 -10.16 -9.46 -6.89 0.54 3.29 -12.84 -12.69 -14.50
Endoplasmic Reticulum -0.00 -4.25 -2.57 -1.66 -0.07 1.74 -8.47 -2.09 -3.31 4.90 2.09 -8.38 -3.27 -4.66 2.38
Endosome 2.31 0.91 -3.07 -4.83 -4.26 -1.50 -4.70 -4.35 -3.62 -1.87 -0.48 -1.81 -5.22 -4.64 -4.56
Golgi 0.10 2.52 -1.18 -1.19 -1.58 -2.11 -1.42 -0.85 0.08 -0.15 -1.38 1.84 -1.41 -0.92 -1.75
Lipid Particles 3.98 15.30 13.75 2.99 -4.06 -6.84 0.38 2.95 9.05 2.80 0.69 15.05 13.16 10.12 -2.62
Mitochondria 3.23 -0.05 3.99 1.42 10.87 -3.75 -2.04 -0.51 1.45 -0.01 -0.64 -1.76 2.14 2.64 4.08
Mitotic Spindle -3.61 -4.63 -4.10 -0.18 -2.43 -3.58 -0.49 -4.59 -2.80 -4.20 -4.73 -4.96 -6.14 -3.23 -4.09
None 3.87 0.64 -1.24 -3.03 -1.50 1.54 3.44 1.99 0.57 -0.77 1.22 3.29 0.13 -0.74 -1.62
Nuclear Periphery 4.67 -17.79 14.71 4.09 39.36 -5.16 -12.68 4.62 9.00 15.59 -0.32 -25.55 13.90 11.34 40.04
Nuclear Periphery Foci -3.97 31.68 32.55 23.09 9.13 4.49 19.10 27.23 23.21 10.21 1.37 41.67 40.54 34.51 10.09
Nucleolus 3.54 5.16 9.65 2.12 8.48 -0.06 8.87 9.81 8.95 2.18 -0.56 9.63 13.50 9.96 6.91
Nucleus 4.29 -28.95 -8.35 -9.94 5.85 4.57 -6.70 -4.41 -7.23 0.46 3.14 -25.12 -8.89 -10.50 6.33
Peroxisomes 0.91 5.25 -0.34 -0.64 -1.34 -3.08 0.20 -2.40 0.23 -2.26 -1.35 5.63 -0.89 -0.34 -2.15
Vacuole -1.24 -13.86 -15.88 -15.56 -14.70 -2.83 -9.83 -14.58 -14.41 -11.96 -2.81 -17.17 -21.41 -21.18 -19.23
Vacuole Periphery -1.24 -2.35 -0.53 1.18 0.16 -2.19 -2.09 0.51 2.27 2.13 -2.44 -3.06 -0.16 2.30 1.45
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline; UBX6 has a paralog, UBX7, that arose from the whole genome duplication
Localization
Cell Percentages nuclear periphery (43%), spindle pole (12%), mixed (7%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ubx6

Ubx6


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ubx6-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available