Standard name
Human Ortholog
Description Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bateria
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0.05 0 0 0.07
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.43 0.21 0.48 0.41 0.66 0.64 0.62 0.57 0.54 0.61 0.59 0.59 0.77 0.82 0.88 0.53 0.49 0.54 0.27 0.06 0.34 0.65 0.59 0.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.12 0 0.07 0.05 0 0.12 0.14 0.19 0.18 0.06 0.14 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.26 0.1 0.11 0.17 0.07 0.09 0 0 0 0 0 0 0.09 0 0 0.09 0.09 0 0.53 0.69 0.48 0.16 0.16 0.13
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.41 0.78 0.54 0.46 0.33 0.25 0.25 0.23 0.23 0.27 0.21 0.27 0.23 0.17 0.11 0.5 0.51 0.52 0.1 0.11 0.09 0.09 0.11 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 2 5 1 2 2 3 0 2 0 0 1 0 0 0 0 0 0 1
Bud 0 1 1 0 0 1 5 10 4 11 3 16 0 1 1 0 1 0 5 6 4 0 5 14
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 4
Bud Site 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 1 4 2 12 5 9 6 12 0 6 6 3 2 2 0 0 0 0 0 0
Cytoplasm 86 26 27 69 145 163 170 172 127 163 87 135 17 160 159 87 120 100 64 8 29 57 89 118
Endoplasmic Reticulum 1 0 0 0 0 1 4 5 6 4 6 9 0 0 1 9 5 4 0 1 0 0 0 1
Endosome 1 2 1 9 5 7 0 1 6 1 0 2 0 2 0 1 3 8 6 1 0 0 2 2
Golgi 0 1 0 2 0 0 1 2 1 1 0 0 0 1 1 1 5 0 0 0 0 0 0 1
Mitochondria 23 0 4 9 8 31 39 58 42 17 20 12 0 1 0 2 0 0 1 4 0 1 0 1
Nucleus 51 13 6 29 15 22 11 13 8 7 2 4 2 4 3 14 23 8 126 100 41 14 23 26
Nuclear Periphery 0 0 0 0 0 0 3 5 6 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 0 1 0 0 0 1 2 1 0 0 0 0 1 0 0 1 0 4 0 0 0 1
Peroxisomes 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 0 1 1 0 1 0 1 2 0 0 0 5 0 0 1 4 4
Vac/Vac Membrane 83 98 30 78 72 62 67 70 54 73 31 62 5 33 20 82 124 97 23 16 7 7 17 14
Unique Cell Count 200 125 56 170 220 253 272 304 235 269 147 229 22 195 181 163 244 186 239 146 87 89 150 197
Labelled Cell Count 245 142 69 198 247 291 305 354 263 290 158 257 24 211 194 199 284 220 239 146 87 89 150 197


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.1 21.7 9.4 8.3 8.5 9.2 14.3 16.7 18.8 26.3 26.4 35.3 6.0 14.2 23.8 12.5 11.9 11.0 7.1 7.6 8.2
Std Deviation (1e-4) 1.3 17.1 4.3 3.2 4.2 5.6 14.3 15.0 17.7 22.4 24.0 29.9 1.8 12.5 21.2 5.0 4.4 4.1 3.1 2.9 4.0
Intensity Change (Log2) – – – -0.19 -0.15 -0.03 0.61 0.83 0.99 1.48 1.49 1.91 -0.65 0.6 1.34 0.41 0.34 0.23 -0.42 -0.31 -0.2


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.0 2.4 2.3 2.0 1.2 0.8 1.7 1.4 1.5 2.3 5.1 6.3 0.7 0.1 0.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 1.1 1.5 2.2 2.0 0 1.3 0 0 0 0 0 0 0
Nucleus 1.1 0 -0.5 0 0 0 0 0 0 0 0 0 -0.5 -0.3 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.0 -2.9 -4.3 -4.3 -4.7 -4.5 -3.9 -4.5 -3.8 -2.5 -5.6 -6.8 -0.4 -0.4 -0.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 13.2613 18.1068 12.7958 11.1762 13.2493 15.0169 8.5657 10.8283 8.9649 9.1566 8.3797 10.5249 8.62 9.2072 8.9662 9.4515 8.625 8.7087
Actin 0.0159 0.0007 0.0069 0.0384 0.0036 0.0006 0.0316 0.0011 0.0093 0.0028 0.009 0.0013 0.0144 0.0003 0.0025 0.0024 0.0399 0.0021
Bud 0.001 0.0008 0.0006 0.0004 0.0006 0.0002 0.0016 0.0008 0.001 0.0003 0.0013 0.0002 0.0008 0.0007 0.0011 0.0003 0.0006 0.0004
Bud Neck 0.0007 0.0003 0.0006 0.002 0.001 0.0009 0.003 0.0008 0.0009 0.0015 0.0018 0.0015 0.0011 0.0004 0.0004 0.0005 0.0011 0.0017
Bud Periphery 0.001 0.0004 0.0002 0.0004 0.0005 0.0001 0.0019 0.0005 0.0005 0.0004 0.0018 0.0002 0.0012 0.0002 0.0004 0.0004 0.0014 0.0021
Bud Site 0.0045 0.0046 0.0006 0.0007 0.0006 0.0001 0.0055 0.0027 0.0011 0.0009 0.0037 0.0004 0.0026 0.0017 0.0014 0.0007 0.0007 0.0003
Cell Periphery 0.0006 0.0001 0.0001 0.0001 0.0002 0 0.0006 0 0.0001 0.0001 0.0001 0 0.0002 0 0.0001 0.0002 0.0001 0.0002
Cytoplasm 0.1038 0.2149 0.125 0.0099 0.1427 0.1248 0.091 0.214 0.0807 0.1029 0.1314 0.0942 0.1371 0.2819 0.0935 0.1039 0.1135 0.1052
Cytoplasmic Foci 0.0184 0.0014 0.0125 0.0065 0.0389 0.0019 0.0225 0.0029 0.0047 0.004 0.0194 0.004 0.0194 0.0018 0.0167 0.0068 0.0014 0.0035
Eisosomes 0.0003 0 0 0.0001 0.0001 0 0.0003 0 0.0001 0.0001 0 0 0.0001 0 0 0.0001 0.0004 0
Endoplasmic Reticulum 0.0046 0.0005 0.0044 0.0005 0.0037 0.0006 0.0104 0.001 0.0012 0.004 0.0042 0.0016 0.0033 0.0015 0.0017 0.0021 0.0019 0.0036
Endosome 0.0204 0.0008 0.008 0.0129 0.0214 0.0023 0.0313 0.0019 0.0141 0.0242 0.0326 0.0127 0.0216 0.0013 0.0057 0.0213 0.0076 0.0153
Golgi 0.004 0.0003 0.0009 0.0287 0.0057 0.0004 0.006 0.0006 0.0065 0.0042 0.006 0.0038 0.0063 0 0.0039 0.0027 0.0052 0.0034
Lipid Particles 0.0103 0.0007 0.0024 0.002 0.0254 0.0016 0.0069 0.0001 0.0072 0.013 0.0145 0.006 0.018 0 0.0082 0.021 0.0023 0.0027
Mitochondria 0.0107 0.0014 0.0009 0.0065 0.0151 0.0004 0.0118 0.0018 0.0138 0.0343 0.0088 0.0045 0.0101 0.0003 0.0061 0.006 0.0059 0.0233
None 0.0033 0.0004 0.003 0.0001 0.0078 0.0005 0.0056 0.0018 0.0032 0.0008 0.0012 0.0005 0.0021 0.004 0.0035 0.0013 0.0009 0.0004
Nuclear Periphery 0.0266 0.0199 0.0129 0.0075 0.0484 0.0176 0.0277 0.0136 0.0079 0.0178 0.0201 0.0084 0.017 0.0166 0.0103 0.0097 0.0401 0.0167
Nucleolus 0.0048 0.0015 0.005 0.0003 0.0024 0.0017 0.0017 0.0008 0.0022 0.0013 0.0016 0.0014 0.0016 0.0009 0.0009 0.0013 0.0034 0.0012
Nucleus 0.7355 0.7345 0.8049 0.8762 0.64 0.8286 0.7124 0.7444 0.818 0.7566 0.6983 0.8462 0.7174 0.6786 0.8295 0.8028 0.7462 0.8039
Peroxisomes 0.0085 0.0022 0.0008 0.0054 0.0092 0.001 0.0058 0.0016 0.0077 0.0035 0.0107 0.0016 0.0031 0.0001 0.0077 0.0029 0.0006 0.0009
Punctate Nuclear 0.0141 0.0127 0.0074 0.0011 0.023 0.0156 0.0138 0.0081 0.0174 0.0226 0.0276 0.0095 0.0137 0.0077 0.0051 0.0025 0.0236 0.0065
Vacuole 0.0082 0.0014 0.0023 0.0003 0.0062 0.0008 0.0064 0.0013 0.0016 0.0032 0.0043 0.0012 0.0067 0.0015 0.0008 0.0076 0.0016 0.0034
Vacuole Periphery 0.0026 0.0005 0.0006 0.0003 0.0038 0.0003 0.0024 0.0002 0.0007 0.0016 0.0016 0.0006 0.0019 0.0003 0.0004 0.0036 0.0014 0.0032

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 3624.9984 3827.0211 4829.7366 2921.0447 3694.6739 3540.1993 3595.208 3703.8799 4833.8396 3218.8028
Translational Efficiency 0.6594 0.6419 0.4934 0.9379 0.6408 0.6529 0.9341 0.9062 0.6261 0.8066

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1803 946 1572 1748 2020 2108 768 1374 3823 3054 2340 3122

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 938.50 1421.51 1041.48 1653.66 723.24 866.54 4702.74 1688.85 824.76 1038.45 2243.12 1669.15
Standard Deviation 265.30 608.47 402.64 1510.31 212.04 196.25 3763.42 1477.22 261.72 455.10 2777.23 1495.94
Intensity Change Log 2 — 0.598996 0.150206 0.817234 — 0.260792 2.700955 1.223495 — 0.461424 1.789416 1.008237

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000118 0.000595 0.000248 0.000767 0.000100 0.000294 0.000413 0.001161 0.000109 0.000388 0.000302 0.000940
Bud Neck 0.006645 0.008155 0.011003 0.005352 0.010763 0.009165 0.006883 0.006533 0.008821 0.008852 0.009650 0.005871
Bud Site 0.006783 0.002715 0.010315 0.023416 0.007619 0.010897 0.013649 0.035688 0.007225 0.008362 0.011410 0.028817
Cell Periphery 0.000173 0.000209 0.000349 0.003032 0.000236 0.000174 0.005338 0.004023 0.000207 0.000185 0.001986 0.003468
Cytoplasm 0.452557* 0.081846 0.367983* 0.657000* 0.567751* 0.498934* 0.621046* 0.644390* 0.513424* 0.369738* 0.451040* 0.651450*
Cytoplasmic Foci 0.017120 0.002819 0.001848 0.014172 0.148098 0.050430 0.032886 0.016389 0.086326 0.035682 0.012035 0.015148
Eisosomes 0.000012 0.000014 0.000011 0.000015 0.000091 0.000030 0.000008 0.000014 0.000054 0.000025 0.000010 0.000015
Endoplasmic Reticulum 0.001053 0.003440 0.001697 0.001182 0.001318 0.001687 0.000352 0.000665 0.001193 0.002230 0.001255 0.000954
Endosome 0.000630 0.000600 0.000396 0.004212 0.007330 0.003308 0.001821 0.005750 0.004170 0.002469 0.000864 0.004889
Golgi 0.000127 0.000550 0.000236 0.007438 0.001433 0.001380 0.005473 0.003839 0.000817 0.001123 0.001955 0.005854
Lipid Particles 0.000477 0.000247 0.000358 0.003619 0.004417 0.001815 0.007330 0.006767 0.002559 0.001330 0.002646 0.005004
Mitochondria 0.001150 0.001338 0.001661 0.001665 0.003008 0.003153 0.000788 0.006000 0.002132 0.002591 0.001374 0.003573
Mitotic Spindle 0.002464 0.008722 0.008122 0.039174 0.001637 0.014606 0.006571 0.031731 0.002027 0.012783 0.007613 0.035898
None 0.013300 0.005613 0.011443 0.007983 0.007478 0.008333 0.006079 0.009835 0.010224 0.007490 0.009682 0.008798
Nuclear Periphery 0.000817 0.001058 0.001770 0.000903 0.000537 0.000999 0.001043 0.000640 0.000669 0.001017 0.001532 0.000787
Nuclear Periphery Foci 0.000493 0.000890 0.000350 0.003079 0.000478 0.000855 0.005327 0.002940 0.000485 0.000866 0.001984 0.003018
Nucleolus 0.001042 0.001255 0.000372 0.000390 0.001090 0.001627 0.000335 0.000302 0.001067 0.001512 0.000360 0.000351
Nucleus 0.484156* 0.871791* 0.563106* 0.150672* 0.195678* 0.367608* 0.149214* 0.147593* 0.331730* 0.523783* 0.427264* 0.149317*
Peroxisomes 0.000407 0.000181 0.000082 0.000540 0.002420 0.002331 0.000084 0.001068 0.001471 0.001665 0.000082 0.000772
Vacuole 0.010238 0.006400 0.018295 0.071518 0.037680 0.021613 0.128272 0.070316 0.024738 0.016901 0.054390 0.070989
Vacuole Periphery 0.000235 0.001564 0.000357 0.003871 0.000836 0.000761 0.007087 0.004355 0.000552 0.001010 0.002566 0.004084

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.30 -5.87 -7.99 1.08 -4.73 -4.04 -10.59 -3.98 -2.81 -1.78 -7.45 -10.90 -6.75 -2.86 -3.77
Bud Neck -3.50 -4.17 1.21 5.01 5.72 1.39 0.40 5.55 4.47 4.26 -1.11 -2.49 5.26 6.50 7.06
Bud Site 2.81 -1.91 -7.00 -10.10 -4.35 -2.36 -6.17 -7.15 -5.21 -2.59 -1.47 -4.38 -10.01 -7.96 -5.31
Cell Periphery -1.86 -1.45 -5.59 -5.19 -4.94 2.48 -12.14 -6.30 -6.54 5.68 0.45 -11.08 -8.35 -8.39 -0.12
Cytoplasm 44.71* 13.87 -13.18 -60.87* -27.34 8.56 0.38 0.20 -7.25 -0.19 19.88 15.14 -8.71 -26.79 -22.14
Cytoplasmic Foci 9.42 11.42 2.92 -9.04 -13.24 20.51 22.09 31.39 13.47 7.74 16.66 27.11 28.23 12.03 -0.02
Eisosomes -2.80 -2.02 -3.45 -0.46 -2.00 13.57 18.28 16.33 6.78 -5.26 10.79 16.59 14.38 6.70 -4.70
Endoplasmic Reticulum -10.12 -7.89 -0.50 9.35 6.76 -1.47 2.89 1.06 4.13 -4.93 -5.34 -3.06 0.68 7.77 5.46
Endosome 0.21 2.92 -3.93 -3.79 -4.43 5.61 7.87 5.93 1.47 -1.16 4.10 9.23 4.47 0.89 -3.99
Golgi -1.83 -1.07 -3.59 -2.94 -3.49 0.20 -6.17 -0.36 -0.45 4.65 -0.86 -3.94 -3.07 -2.15 -1.41
Lipid Particles 2.62 0.29 -7.73 -8.29 -7.81 6.97 -3.85 -0.31 -4.25 2.94 5.38 -0.62 -3.05 -6.46 -2.27
Mitochondria -1.51 -2.86 0.24 1.97 3.39 -0.10 3.72 0.37 0.46 -2.03 -0.94 1.78 0.72 1.53 -0.56
Mitotic Spindle -3.02 -4.41 -9.44 -4.62 -5.99 -6.36 -4.48 -8.74 -3.65 -5.80 -6.88 -6.19 -12.97 -5.67 -8.16
None 7.47 2.83 6.29 -2.56 3.02 -0.83 3.04 -0.64 0.23 -4.60 3.96 2.51 4.21 -0.02 1.10
Nuclear Periphery -3.00 -12.77 -3.35 0.41 10.84 -2.39 -3.67 -4.09 -0.22 1.26 -2.87 -12.67 -5.58 -0.32 8.52
Nuclear Periphery Foci -1.44 0.81 -8.09 -3.77 -8.62 -2.13 -8.11 -8.54 -5.15 4.85 -2.53 -7.41 -11.62 -6.55 -1.10
Nucleolus -0.64 3.40 4.22 3.56 1.72 -2.75 6.78 7.43 7.22 2.07 -2.63 6.20 7.70 7.90 2.45
Nucleus -38.49* -11.10 31.89 79.38* 44.68 -21.90 2.83 -1.49 17.94 -3.74 -23.70 -15.40 20.70 42.07 32.65
Peroxisomes 1.44 3.71 0.59 -0.66 -2.17 0.08 10.55 6.37 4.63 -1.65 -0.87 11.09 6.40 4.86 -2.61
Vacuole 1.95 -8.88 -26.60 -27.02 -21.20 6.41 -13.93 -16.41 -19.28 2.73 4.25 -13.51 -29.80 -31.52 -13.14
Vacuole Periphery -1.46 -0.64 -3.45 -0.31 -3.28 0.64 -5.02 -2.24 -2.38 3.37 -1.47 -4.48 -3.88 -1.96 0.20
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bateria
Localization
Cell Percentages cytoplasm (65%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Tdh1

Tdh1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tdh1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available