Standard name
Human Ortholog
Description Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.95 0.96 0.96 – 0.98 0.9 0.88 0.88 0.67 0.79 0.55 0.72 0.99 0.99 0.99 0.94 0.97 0.97 0.7 0.78 0.52 0.87 0.84 0.85
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0 0.06 0.07 0.07 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 – 0 0.05 0.09 0.1 0.37 0.22 0.52 0.24 0 0 0 0 0 0 0.15 0.1 0.23 0 0.05 0
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 – 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0.07 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 – 0 1 0 0 1 1 1 1 0 0 0 0 0 1 5 4 2 3 6 7
Bud 3 0 0 – 0 2 1 2 3 2 4 3 0 0 0 0 0 0 1 1 1 1 11 10
Bud Neck 0 2 1 – 0 3 2 4 0 0 2 2 3 1 0 5 2 0 1 3 1 0 1 3
Bud Site 1 0 0 – 0 0 0 0 0 0 2 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 5 2 1 – 1 5 2 1 0 1 0 4 2 1 5 2 1 3 2 3 1 0 3 5
Cytoplasm 362 321 80 – 114 178 248 221 66 140 96 179 365 478 623 335 253 223 283 271 53 149 405 442
Endoplasmic Reticulum 2 10 1 – 0 7 6 3 5 2 3 6 2 1 0 21 18 16 13 7 2 1 2 2
Endosome 1 0 0 – 1 0 5 1 0 0 0 5 1 2 1 6 0 1 5 1 2 1 4 4
Golgi 1 0 0 – 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 1 0 0 2 1
Mitochondria 17 3 0 – 0 9 25 24 36 39 91 60 0 0 0 13 3 2 61 35 23 7 23 19
Nucleus 0 1 1 – 0 1 2 2 2 2 1 2 1 1 1 1 1 1 0 0 0 0 3 0
Nuclear Periphery 1 2 0 – 0 0 0 1 0 2 0 0 0 0 0 1 0 0 1 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 1 0 0 0 1 1 0 0 0 1 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 0 0
SpindlePole 2 0 1 – 1 1 4 2 0 0 6 6 1 1 1 1 1 0 1 4 0 0 5 8
Vac/Vac Membrane 5 4 0 – 1 1 5 7 1 10 3 7 0 0 3 11 6 3 17 6 6 2 1 8
Unique Cell Count 380 334 83 116 197 283 251 98 177 174 249 370 485 629 358 262 229 406 347 102 172 485 522
Labelled Cell Count 400 345 85 118 208 300 268 114 200 209 275 375 486 636 400 286 250 406 347 102 172 485 522


(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 4.2 5.3 – 5.8 4.6 5.0 5.2 3.7 4.5 3.8 4.2 5.3 5.3 5.5 5.7 5.6 5.0 5.3 5.1 5.5
Std Deviation (1e-4) 0.7 0.7 1.7 – 1.6 1.0 1.8 1.5 0.9 1.4 0.9 1.1 1.2 1.3 1.5 1.1 1.8 1.0 1.6 1.4 1.6
Intensity Change (Log2) – – – – 0.13 -0.21 -0.09 -0.04 -0.5 -0.22 -0.47 -0.33 0.01 0.01 0.06 0.1 0.08 -0.07 -0.01 -0.04 0.05


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.27 -0.2808 -0.2057 -0.1874 0.0728 -0.3839 -0.6591 -0.4987 -0.3714 -0.7108 -0.4833 -0.5075 -1.1643 -0.7281 -1.0387 -0.8984 -0.8518 -0.7486
Actin 0.01 0.0006 0.0246 0.0182 0.0523 0.0004 0.0312 0.0003 0.0028 0.0026 0.0039 0.0018 0.0331 0.0009 0.0097 0.0003 0.0159 0.0146
Bud 0.002 0.0012 0.0034 0.0004 0.001 0.0008 0.0066 0.0138 0.0066 0.0046 0.0005 0.0005 0.0007 0.0067 0.0016 0.0001 0.0001 0.0003
Bud Neck 0.011 0.0002 0.0044 0.0009 0.001 0.0009 0.0081 0.0001 0.0004 0.0023 0.0011 0.0002 0.0026 0.0001 0.0003 0.0001 0.0003 0.0163
Bud Periphery 0.0056 0.0038 0.0056 0.0009 0.0015 0.0013 0.0053 0.0019 0.0074 0.0019 0.0014 0.0004 0.0023 0.0056 0.0026 0.0004 0.0003 0.0005
Bud Site 0.0074 0.0071 0.0158 0.0002 0.0091 0.0001 0.0164 0.0095 0.0125 0.0041 0.0007 0.0004 0.0015 0.0041 0.0024 0 0.0003 0.0008
Cell Periphery 0.0014 0.0003 0.001 0.0001 0.0004 0.0001 0.0005 0.0003 0.0003 0.0005 0.0002 0.0001 0.0003 0.0003 0.0002 0.0001 0.0001 0.0001
Cytoplasm 0.0329 0.0338 0.0392 0.0473 0.0304 0.0857 0.0196 0.0712 0.0278 0.0343 0.0671 0.0578 0.0832 0.1721 0.1608 0.2105 0.1748 0.2129
Cytoplasmic Foci 0.0203 0.0073 0.0226 0.011 0.0287 0.0229 0.0178 0.0045 0.0219 0.0324 0.0038 0.0049 0.0183 0.0054 0.0163 0.0026 0.0134 0.0131
Eisosomes 0.0006 0.0003 0.0005 0.0002 0.0008 0.0002 0.0023 0.0002 0.0003 0.0002 0.0001 0.0001 0.0007 0.0003 0.0003 0.0001 0.0002 0.0001
Endoplasmic Reticulum 0.0099 0.0017 0.0029 0.0018 0.0027 0.0009 0.0015 0.0017 0.001 0.0166 0.0016 0.0007 0.0056 0.003 0.0052 0.0018 0.0048 0.004
Endosome 0.0179 0.0013 0.0117 0.0131 0.0585 0.0037 0.0179 0.002 0.0107 0.0131 0.0232 0.0024 0.0199 0.0019 0.0145 0.0007 0.0089 0.0074
Golgi 0.0068 0.0003 0.0069 0.0199 0.0214 0.0005 0.0089 0.0004 0.0058 0.0081 0.0078 0.0038 0.0057 0.0002 0.002 0.0001 0.0055 0.0014
Lipid Particles 0.0153 0.0008 0.0097 0.0032 0.0411 0.0013 0.0195 0.0007 0.0092 0.0051 0.0057 0.0013 0.007 0.0009 0.0073 0.0002 0.0148 0.0041
Mitochondria 0.0166 0.0011 0.0114 0.0445 0.0447 0.0006 0.007 0.0003 0.0131 0.0035 0.0047 0.008 0.0017 0.0005 0.0067 0.0003 0.001 0.0052
None 0.8187 0.9338 0.8121 0.8306 0.6598 0.8691 0.8074 0.8885 0.8646 0.8522 0.8699 0.9053 0.7912 0.7935 0.7521 0.7802 0.7432 0.7036
Nuclear Periphery 0.0034 0.0005 0.0025 0.0011 0.0016 0.0015 0.0028 0.0004 0.0004 0.0076 0.0011 0.0008 0.0094 0.0008 0.0023 0.0007 0.0044 0.0054
Nucleolus 0.0007 0.0005 0.0011 0.0002 0.0013 0.0003 0.0015 0.0004 0.0006 0.0008 0.0003 0.0037 0.0003 0.0003 0.0005 0.0001 0.0003 0.0008
Nucleus 0.0015 0.0008 0.0014 0.0006 0.0011 0.0043 0.0037 0.0015 0.0019 0.0018 0.0005 0.0018 0.0019 0.0011 0.0017 0.0006 0.0013 0.0022
Peroxisomes 0.0122 0.0013 0.0097 0.0026 0.026 0.0011 0.0129 0.0001 0.008 0.0033 0.0008 0.0004 0.0088 0.0002 0.0061 0.0001 0.0027 0.0032
Punctate Nuclear 0.0018 0.0021 0.0033 0.0008 0.0016 0.0035 0.0071 0.0017 0.0038 0.0015 0.0009 0.0053 0.0038 0.0011 0.003 0.0004 0.005 0.0025
Vacuole 0.0031 0.0011 0.0092 0.0016 0.013 0.0006 0.0011 0.0005 0.0008 0.0026 0.0033 0.0003 0.0013 0.0011 0.0031 0.0004 0.0022 0.0011
Vacuole Periphery 0.0009 0.0002 0.0013 0.0007 0.0021 0.0001 0.0007 0.0001 0.0003 0.0009 0.0014 0.0002 0.0008 0.0001 0.0009 0.0001 0.0005 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 4.4048 5.9064 6.209 6.4307 1.0708 7.1539 4.6034 6.8858 6.9256 6.3229
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2290 1332 878 1469 1321 1546 321 2511 3611 2878 1199 3980

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 609.03 677.86 882.16 862.57 676.47 692.93 903.85 876.35 633.70 685.96 887.97 871.26
Standard Deviation 62.11 101.75 95.85 124.51 73.20 87.23 100.34 115.64 73.91 94.53 97.55 119.18
Intensity Change Log 2 — 0.154474 0.534527 0.502128 — 0.034684 0.418057 0.373481 — 0.092678 0.474411 0.435862

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000139 0.000130 0.000329 0.001998 0.000121 0.000242 0.000178 0.000776 0.000132 0.000190 0.000289 0.001227
Bud Neck 0.026354 0.012264 0.005301 0.013741 0.015159 0.042129 0.002323 0.015728 0.022259 0.028307 0.004504 0.014995
Bud Site 0.005694 0.005429 0.009470 0.051551 0.003755 0.013481 0.002889 0.039088 0.004984 0.009755 0.007708 0.043688
Cell Periphery 0.000185 0.000115 0.000275 0.000678 0.000176 0.000171 0.000256 0.000400 0.000182 0.000145 0.000270 0.000503
Cytoplasm 0.473332* 0.493731* 0.303745* 0.428792* 0.451842* 0.387803* 0.426079* 0.504341* 0.465470* 0.436829* 0.336497* 0.476457*
Cytoplasmic Foci 0.221109* 0.157962 0.021372 0.046481 0.275097* 0.243919* 0.050359 0.021880 0.240859* 0.204136* 0.029133 0.030960
Eisosomes 0.000371 0.000079 0.000072 0.000188 0.000253 0.000193 0.000118 0.000065 0.000328 0.000141 0.000084 0.000110
Endoplasmic Reticulum 0.001072 0.001235 0.006911 0.008489 0.000990 0.001605 0.004120 0.002332 0.001042 0.001434 0.006164 0.004605
Endosome 0.009149 0.009552 0.004566 0.008824 0.011661 0.024236 0.007811 0.003866 0.010068 0.017440 0.005434 0.005696
Golgi 0.004052 0.000929 0.000173 0.004198 0.003533 0.004897 0.000121 0.001006 0.003862 0.003060 0.000159 0.002184
Lipid Particles 0.011754 0.007952 0.003857 0.004404 0.014897 0.011913 0.005554 0.001525 0.012904 0.010080 0.004311 0.002588
Mitochondria 0.007152 0.005695 0.000839 0.002851 0.004584 0.014150 0.002764 0.003050 0.006213 0.010236 0.001355 0.002977
Mitotic Spindle 0.000510 0.001902 0.005351 0.017288 0.000606 0.007072 0.000721 0.023172 0.000545 0.004679 0.004111 0.021000
None 0.005900 0.008141 0.003972 0.003164 0.003337 0.002757 0.002613 0.003969 0.004962 0.005249 0.003608 0.003672
Nuclear Periphery 0.000394 0.000935 0.003589 0.001832 0.000461 0.000863 0.001987 0.001369 0.000418 0.000896 0.003160 0.001540
Nuclear Periphery Foci 0.000374 0.000768 0.003511 0.005280 0.000380 0.000329 0.005182 0.001508 0.000376 0.000532 0.003958 0.002900
Nucleolus 0.001704 0.002601 0.001126 0.000540 0.001131 0.001714 0.000489 0.000429 0.001495 0.002124 0.000955 0.000470
Nucleus 0.178910* 0.235290* 0.548609* 0.207894* 0.163977* 0.139576* 0.309259* 0.290673* 0.173447* 0.183874* 0.484529* 0.260120*
Peroxisomes 0.004818 0.004423 0.000543 0.001827 0.007297 0.014101 0.000503 0.001420 0.005725 0.009622 0.000532 0.001570
Vacuole 0.046012 0.049348 0.075641 0.186563 0.039677 0.085745 0.176484 0.082273 0.043695 0.068899 0.102639 0.120766
Vacuole Periphery 0.001014 0.001516 0.000749 0.003418 0.001066 0.003105 0.000189 0.001129 0.001033 0.002370 0.000599 0.001974

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.28 -6.84 -5.47 -5.49 -4.39 -3.27 -2.69 -3.07 -2.56 -2.34 -2.84 -7.33 -5.60 -5.26 -4.15
Bud Neck 7.24 12.88 8.39 0.10 -4.08 -9.68 8.59 0.69 10.65 -10.10 -3.30 14.65 7.38 8.95 -8.21
Bud Site 0.38 -1.75 -9.52 -9.45 -7.62 -6.21 0.05 -12.46 -7.27 -12.41 -4.91 -1.84 -15.54 -12.09 -11.92
Cell Periphery 7.56 -4.76 -7.95 -9.53 -5.36 0.56 -4.88 -5.28 -5.33 -1.61 4.85 -6.29 -9.05 -10.39 -4.50
Cytoplasm -1.65 21.14 11.90 11.42 -9.04 6.66 5.51 -1.00 -8.32 -6.25 4.83 20.48 6.46 1.04 -15.43
Cytoplasmic Foci 9.72 46.43 40.76 22.96 -8.63 3.79 33.75 43.03 38.65 7.20 6.99 58.11 60.84 44.34 -0.49
Eisosomes 7.99 7.89 5.21 -7.33 -6.92 3.76 7.16 12.88 14.67 8.01 7.81 9.64 9.23 5.12 -1.25
Endoplasmic Reticulum -1.15 -14.10 -12.89 -12.46 0.39 -1.37 -7.58 -7.00 -3.28 4.42 -1.68 -15.73 -15.43 -11.24 5.99
Endosome -0.49 6.24 3.32 3.28 -1.33 -7.52 3.57 10.00 13.92 6.21 -7.48 7.65 10.32 14.00 3.44
Golgi 7.77 9.89 2.40 -1.86 -2.98 -2.03 8.15 5.96 7.62 -2.50 2.10 12.67 6.39 4.50 -3.76
Lipid Particles 4.03 10.66 11.12 4.79 -0.62 2.14 7.62 12.81 10.14 5.44 3.45 13.33 18.40 11.53 5.30
Mitochondria 1.31 8.80 5.57 3.14 -1.25 -5.93 1.53 2.53 7.69 -0.31 -3.74 7.48 6.23 8.06 -1.71
Mitotic Spindle -2.26 -2.78 -6.29 -5.30 -3.38 -4.30 0.30 -9.17 -5.28 -9.30 -4.97 -2.67 -11.20 -7.53 -7.65
None -1.65 2.86 4.09 5.25 1.91 0.93 2.07 -0.21 -1.58 -3.26 -0.25 3.14 3.30 3.76 -0.02
Nuclear Periphery -4.16 -17.06 -10.38 -6.66 5.72 -2.29 -11.73 -14.00 -5.93 1.11 -4.27 -19.23 -17.04 -8.96 7.53
Nuclear Periphery Foci -4.45 -8.91 -10.14 -9.31 -2.94 0.83 -8.41 -5.95 -6.02 5.99 -2.46 -11.92 -11.57 -10.81 2.78
Nucleolus -2.18 1.68 5.95 5.61 3.07 -2.82 4.92 5.27 9.44 0.43 -2.70 2.36 7.91 8.82 3.33
Nucleus -8.69 -36.77 -4.72 3.75 31.37 3.92 -9.48 -20.04 -24.49 -0.52 -2.54 -34.73 -20.15 -15.60 22.92
Peroxisomes 0.45 10.62 7.92 5.70 -2.60 -4.96 8.49 7.42 11.37 -2.27 -5.19 13.32 10.84 12.58 -3.08
Vacuole -1.72 -10.56 -31.66 -30.02 -20.35 -12.63 -13.99 -21.15 -7.93 8.04 -10.72 -16.64 -35.36 -26.11 -6.06
Vacuole Periphery -2.05 1.45 -1.41 -0.58 -1.90 -5.22 6.87 1.16 5.54 -3.27 -5.65 2.75 -0.59 3.55 -2.22
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p
Localization
Cell Percentages cytoplasm (34%), ER (1%), mixed (38%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Iks1

Iks1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Iks1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available