ORF
Human Ortholog
Description Esterase that can function as an S-formylglutathione hydrolase; non-essential intracellular esterase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.98 0.97 0.97 0.95 0.89 0.8 0.79 0.67 0.68 0.64 0.66 0.99 1.0 1.0 0.98 0.99 1.0 0.91 0.93 0.88 0.94 0.92 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.1 0 0.08 0.18 0.11 0.44 0.36 0.36 0.32 0 0 0 0 0 0 0 0 0.05 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.06 0.12 0.16 0.11 0.06 0.09 0.08 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Bud 0 0 0 0 0 0 1 0 2 6 3 4 0 0 0 0 0 0 0 0 0 1 2 1
Bud Neck 0 1 0 0 1 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 0 0 2 3 4 4 2 1 0 3 1 1 2 0 1 0 0 0 0 0 0 0
Cytoplasm 108 360 32 75 152 177 179 266 145 159 121 172 148 242 247 46 68 40 118 347 70 90 146 96
Endoplasmic Reticulum 0 1 0 0 0 1 0 0 1 3 1 4 0 1 0 1 2 2 0 0 1 0 0 1
Endosome 1 0 1 0 0 2 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0
Mitochondria 2 8 0 8 2 16 41 36 97 84 67 84 0 0 0 0 1 0 3 6 3 1 1 2
Nucleus 0 1 0 0 0 1 5 3 6 5 4 11 0 1 0 0 0 0 0 1 0 0 0 1
Nuclear Periphery 0 1 0 0 0 0 1 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 1 1 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 1 0 0 1 0 2 3 0 0 1 0 0 0 0 0 0 0 0 1 0 0 1 1
Vac/Vac Membrane 1 3 0 0 6 11 26 55 25 15 17 21 1 1 0 1 2 1 2 3 0 1 1 1
Unique Cell Count 111 368 33 77 160 200 223 335 218 234 188 261 150 243 247 47 69 40 130 372 80 97 159 116
Labelled Cell Count 114 378 33 83 164 211 261 370 279 276 215 303 152 246 249 49 74 43 130 372 80 97 159 116


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.6 4.2 5.3 4.7 6.4 5.8 5.4 6.0 4.7 5.0 5.1 5.3 5.5 6.0 5.4 7.8 9.5 10.6 5.4 5.7 5.3
Std Deviation (1e-4) 1.5 0.9 0.7 1.3 2.0 1.8 1.3 1.3 1.5 1.4 1.7 1.5 1.6 1.8 1.3 1.4 2.0 2.2 1.7 1.7 1.2
Intensity Change (Log2) – – – -0.17 0.28 0.12 0.01 0.17 -0.18 -0.09 -0.05 -0.0 0.06 0.16 0.01 0.56 0.84 1.0 0.03 0.11 -0.01

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.4825 3.0806 2.3047 1.7385 1.5972 1.9125 2.9097 4.1396 3.5083 3.5765 3.0019 3.8153 0.4872 1.525 1.1634 1.1345 0.8998 1.1286
Actin 0.0295 0.0007 0.0033 0.0185 0.0001 0.0045 0.0009 0.0002 0.0004 0.0003 0.0006 0.0011 0.0001 0.0013 0.0002 0.0007 0.0001 0.002
Bud 0.001 0.0002 0.0002 0.0126 0 0.0005 0 0.0001 0.0041 0 0.0001 0.0004 0.0001 0.0005 0.0002 0.0001 0.0002 0.0002
Bud Neck 0.0052 0.0003 0.0006 0.0217 0.0002 0.0005 0.0001 0.0001 0.0001 0.0001 0.0002 0.0003 0.0001 0.0003 0.0001 0.0002 0.0012 0.0006
Bud Periphery 0.0012 0.0002 0.0002 0.0136 0 0.0005 0 0.0001 0.0018 0 0.0001 0.0009 0.0001 0.0004 0.0003 0.0001 0.0002 0.0003
Bud Site 0.0109 0.0025 0.0034 0.0127 0 0.0001 0.0001 0.0005 0.0008 0.0001 0.0001 0.0001 0.0002 0.0101 0.0003 0.0001 0.003 0.0001
Cell Periphery 0.0003 0.0002 0.0002 0.0006 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0 0 0.0001
Cytoplasm 0.2113 0.4887 0.3947 0.4378 0.5823 0.4792 0.3305 0.5077 0.4693 0.3016 0.4433 0.5707 0.399 0.5258 0.4293 0.4662 0.3855 0.4841
Cytoplasmic Foci 0.0437 0.0041 0.0088 0.0068 0.0066 0.0114 0.0045 0.0048 0.0063 0.0035 0.008 0.0087 0.0043 0.0039 0.0044 0.0116 0.0208 0.0083
Eisosomes 0.0004 0 0.0002 0.0003 0 0.0001 0.0002 0 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0 0 0
Endoplasmic Reticulum 0.0039 0.0013 0.0015 0.002 0.0017 0.0032 0.0037 0.002 0.0024 0.0011 0.0016 0.0019 0.0014 0.0011 0.001 0.0007 0.0007 0.001
Endosome 0.0296 0.0008 0.0104 0.0037 0.0019 0.0018 0.0036 0.0012 0.0018 0.0006 0.0018 0.0051 0.0012 0.0007 0.0012 0.0018 0.0012 0.0015
Golgi 0.0117 0.0001 0.001 0.0019 0.0001 0.0004 0.0002 0.0001 0.0001 0.0001 0.0002 0.0024 0.0001 0.0001 0.0001 0.0002 0.0005 0.0001
Lipid Particles 0.0204 0.0002 0.0013 0.0008 0 0.0003 0.0002 0.0001 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0002 0.0003 0.0002
Mitochondria 0.005 0.0001 0.0023 0.0021 0.0002 0.0006 0.0002 0.0001 0.0015 0.0001 0.0002 0.0008 0.0002 0.0002 0.0002 0.0004 0.0002 0.0002
None 0.5644 0.4975 0.5575 0.4363 0.4039 0.4929 0.6418 0.4804 0.5067 0.6905 0.5411 0.4035 0.5889 0.4509 0.5571 0.5127 0.5794 0.4978
Nuclear Periphery 0.0064 0.0003 0.0007 0.0019 0.0004 0.0007 0.0087 0.0005 0.0006 0.0003 0.0004 0.0006 0.0004 0.0009 0.0005 0.0004 0.0002 0.0003
Nucleolus 0.0048 0.0001 0.0003 0.001 0 0.0001 0.0001 0 0.0003 0 0 0.0001 0.0001 0.0001 0.0004 0.0001 0.0004 0.0001
Nucleus 0.0053 0.0012 0.0012 0.0193 0.0012 0.0011 0.0032 0.0011 0.0018 0.0007 0.0008 0.0009 0.0027 0.0019 0.0021 0.003 0.001 0.0015
Peroxisomes 0.0299 0.0001 0.0054 0.0018 0.0002 0.0006 0 0 0.0002 0.0001 0.0003 0.0008 0.0001 0.0002 0.0001 0.0005 0.0016 0.0002
Punctate Nuclear 0.011 0.0003 0.0057 0.0019 0.0005 0.001 0.0006 0.0003 0.0006 0.0003 0.0007 0.0008 0.0005 0.001 0.0016 0.0009 0.003 0.001
Vacuole 0.0031 0.0009 0.001 0.0022 0.0004 0.0004 0.0008 0.0004 0.0007 0.0003 0.0003 0.0004 0.0005 0.0005 0.0006 0.0003 0.0005 0.0004
Vacuole Periphery 0.001 0 0.0002 0.0003 0.0001 0.0001 0.0003 0.0001 0.0001 0 0.0001 0.0001 0 0.0001 0.0001 0.0001 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 46.5882 43.8389 40.663 47.4728 59.6088 40.4358 46.8188 52.7282 65.0028 57.4241
Translational Efficiency 1.9069 1.6103 1.3803 1.4652 1.3685 2.5453 1.8373 1.9152 1.4729 1.5522

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1991 1598 2120 2011 1730 2587 249 1729 3721 4185 2369 3740

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 701.87 774.74 807.03 849.34 658.00 806.75 912.56 846.98 681.47 794.53 818.12 848.25
Standard Deviation 80.30 179.95 97.18 112.03 82.46 90.98 105.69 127.51 84.20 133.13 103.31 119.44
Intensity Change Log 2 — 0.142508 0.201418 0.275138 — 0.294034 0.471832 0.364240 — 0.217816 0.338596 0.318940

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000260 0.000303 0.000070 0.000329 0.000081 0.000156 0.000282 0.000765 0.000177 0.000212 0.000093 0.000531
Bud Neck 0.014152 0.021002 0.003076 0.008170 0.014318 0.035480 0.001416 0.008481 0.014229 0.029952 0.002901 0.008314
Bud Site 0.003742 0.013578 0.006417 0.024601 0.002402 0.012922 0.002378 0.039590 0.003119 0.013173 0.005992 0.031531
Cell Periphery 0.000099 0.000155 0.000080 0.000104 0.000074 0.000148 0.000184 0.000143 0.000088 0.000151 0.000091 0.000122
Cytoplasm 0.497886 0.489466 0.519189 0.568432 0.525261 0.513990 0.418414 0.560602 0.510613 0.504625 0.508596 0.564812
Cytoplasmic Foci 0.212991 0.258986 0.009047 0.012992 0.184989 0.178331 0.034856 0.019353 0.199972 0.209128 0.011760 0.015933
Eisosomes 0.000127 0.000123 0.000015 0.000029 0.000115 0.000131 0.000075 0.000036 0.000121 0.000128 0.000021 0.000032
Endoplasmic Reticulum 0.000683 0.000936 0.000783 0.001187 0.000964 0.000431 0.002615 0.001323 0.000814 0.000623 0.000976 0.001250
Endosome 0.008044 0.016035 0.000961 0.002011 0.007833 0.013768 0.003950 0.007070 0.007946 0.014634 0.001275 0.004350
Golgi 0.002142 0.006058 0.000045 0.000436 0.001882 0.003151 0.000080 0.003045 0.002021 0.004261 0.000049 0.001642
Lipid Particles 0.008657 0.005814 0.000414 0.000855 0.007828 0.004257 0.002466 0.000885 0.008272 0.004852 0.000630 0.000869
Mitochondria 0.004869 0.006866 0.000386 0.003002 0.002774 0.007212 0.000219 0.002974 0.003895 0.007080 0.000369 0.002989
Mitotic Spindle 0.001644 0.003083 0.004616 0.047771 0.000635 0.005158 0.002117 0.033744 0.001175 0.004366 0.004353 0.041287
None 0.002972 0.003489 0.006499 0.004701 0.002522 0.004053 0.004762 0.006754 0.002763 0.003837 0.006316 0.005651
Nuclear Periphery 0.000488 0.000263 0.000931 0.001521 0.000398 0.000310 0.001366 0.001526 0.000446 0.000292 0.000977 0.001523
Nuclear Periphery Foci 0.000267 0.000447 0.000316 0.000696 0.000257 0.000149 0.002806 0.001907 0.000262 0.000262 0.000578 0.001256
Nucleolus 0.000904 0.001168 0.000297 0.000493 0.000890 0.001540 0.000513 0.000994 0.000897 0.001398 0.000320 0.000724
Nucleus 0.193497 0.112412 0.422798 0.238991 0.201646 0.157753 0.439920 0.217681 0.197286 0.140440 0.424598 0.229139
Peroxisomes 0.004373 0.009205 0.000093 0.000450 0.003746 0.006237 0.000416 0.002107 0.004081 0.007370 0.000127 0.001216
Vacuole 0.041422 0.048959 0.023849 0.081925 0.040830 0.053584 0.081046 0.087924 0.041147 0.051818 0.029861 0.084698
Vacuole Periphery 0.000781 0.001651 0.000117 0.001305 0.000556 0.001241 0.000118 0.003093 0.000676 0.001397 0.000117 0.002131

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.33 1.17 -0.30 0.05 -4.32 -4.36 -2.55 -6.29 -5.10 -0.65 -0.48 0.66 -2.55 -4.30 -6.21
Bud Neck -3.67 9.02 5.12 8.39 -5.99 -10.59 11.04 4.95 15.12 -7.53 -11.08 12.65 7.12 17.46 -7.56
Bud Site -7.32 -2.06 -7.03 -0.61 -4.81 -10.39 -1.22 -10.01 -4.82 -9.13 -12.13 -2.78 -12.18 -4.06 -8.45
Cell Periphery -4.79 2.40 2.02 6.47 -0.76 -10.11 -6.85 -6.44 4.16 4.34 -9.45 -0.55 -2.09 8.11 -1.04
Cytoplasm 0.93 1.11 4.86 3.48 3.58 1.33 10.40 6.67 5.87 -6.50 0.97 4.97 8.12 7.19 1.96
Cytoplasmic Foci -6.29 43.96 43.21 43.35 -3.03 1.18 27.12 35.34 41.12 3.05 -1.93 56.51 55.66 59.08 -3.59
Eisosomes 0.45 17.52 13.69 16.42 -14.70 -2.01 2.86 11.80 14.58 5.50 -1.18 21.89 18.07 20.83 -11.72
Endoplasmic Reticulum -1.68 -3.89 -9.77 -6.25 -7.66 3.08 -7.61 -4.84 -12.10 5.65 1.76 -5.39 -9.62 -14.12 -4.79
Endosome -6.87 12.47 10.49 13.74 -4.74 -5.65 4.64 4.39 9.87 0.06 -8.69 15.15 9.99 16.93 -5.85
Golgi -5.50 5.79 5.15 9.45 -2.06 -2.76 5.79 1.33 3.96 -3.62 -5.65 8.17 4.51 10.09 -4.15
Lipid Particles 3.40 11.15 10.28 11.50 -11.31 4.94 6.72 10.19 10.77 4.15 6.18 15.15 14.36 15.70 -6.65
Mitochondria -1.50 5.32 3.39 4.80 -2.72 -5.56 9.38 2.56 6.76 -5.02 -4.16 7.52 4.05 8.16 -4.67
Mitotic Spindle -1.30 -3.68 -10.72 -9.90 -8.71 -4.49 -1.10 -11.18 -9.25 -8.50 -4.13 -4.41 -15.44 -13.36 -12.01
None -0.78 -4.43 -6.86 -4.12 -0.14 -2.60 -2.48 -6.04 -2.69 -3.18 -2.41 -5.29 -9.06 -4.53 -0.63
Nuclear Periphery 4.01 -11.73 -22.06 -25.34 -16.69 2.30 -13.23 -15.24 -15.86 -3.75 4.44 -18.48 -26.14 -28.53 -16.85
Nuclear Periphery Foci -4.10 -3.02 -8.97 -6.56 -7.28 3.85 -7.13 -4.16 -4.43 2.97 -0.08 -7.36 -6.30 -6.28 -3.55
Nucleolus -1.51 5.92 -0.89 0.54 -4.96 -4.01 4.37 -1.45 0.54 -2.71 -4.10 8.78 -1.70 1.05 -5.13
Nucleus 15.37 -32.75 -14.26 -28.10 18.55 8.05 -14.26 -7.92 -15.07 10.72 14.82 -36.70 -15.79 -29.06 23.47
Peroxisomes -5.64 10.85 9.90 11.59 -3.55 -4.76 8.67 5.60 10.15 -1.88 -7.12 14.94 10.95 16.37 -3.81
Vacuole -3.21 2.37 -25.28 -23.39 -25.81 -5.25 -8.81 -23.06 -20.78 -2.80 -6.26 -2.21 -34.21 -31.06 -29.69
Vacuole Periphery -5.26 7.13 1.08 4.22 -1.70 -6.63 10.01 -2.22 -0.31 -3.44 -7.61 10.33 -1.05 2.24 -3.78
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Esterase that can function as an S-formylglutathione hydrolase; non-essential intracellular esterase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D
Localization
Cell Percentages cytoplasm (38%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YJL068C

YJL068C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yjl068c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available