Standard name
Human Ortholog
Description Protein involved in the inositol acylation of GlcN-PI; the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) forms glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.08 0.11 0 0 0 0 0 0 0 0 0.07 0.08 0.09 0.13 0.12 0.16 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0.06 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 0 0 0 0.05 0 0 0 0 0.11 0.13 0.19 0 0 0 0 0 0
Cytoplasm 0.27 0.26 0.18 0.25 0.32 0.32 0.33 0.3 0.3 0.43 0.39 0.35 0.23 0.27 0.33 0.64 0.69 0.52 0 0 0 0 0 0.05
Endoplasmic Reticulum 0.74 0.77 0.79 0.49 0.29 0.37 0.25 0.26 0.22 0.1 0.18 0.18 0.76 0.7 0.62 0 0 0 0.87 0.87 0.87 0.81 0.8 0.77
Endosome 0 0 0 0.08 0.14 0 0.08 0 0.05 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.16 0.1 0.32 0.34 0.31 0.43 0.38 0.46 0.48 0 0 0 0.07 0.05 0 0 0 0 0.05 0.05 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.05 0 0 0.07 0.22 0.09 0.11 0.16 0.13 0.14 0.06 0.11 0 0 0 0 0.05 0.14 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 11 10 39 29 12 8 12 19 17 4 16 14 20 38 20 6 18 10 4 8 18 10 17 19
Bud 3 2 1 8 5 11 14 22 26 37 21 33 4 3 0 2 3 1 0 0 0 0 1 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 0 1 2 3
Bud Site 0 0 0 0 0 0 1 1 4 3 1 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 8 4 9 13 14 8 19 12 13 22 25 19 4 6 5 5 20 12 0 1 1 2 7 6
Cytoplasm 88 87 85 68 105 137 170 171 190 255 214 196 62 134 73 29 106 33 15 12 7 11 16 26
Endoplasmic Reticulum 236 262 362 133 94 160 129 144 136 59 99 100 202 345 135 0 6 0 314 325 455 277 396 431
Endosome 2 1 15 21 46 18 40 18 31 26 9 11 5 20 6 1 3 3 2 2 5 2 6 10
Golgi 2 1 3 4 2 1 0 1 0 0 0 1 0 4 2 0 0 1 4 4 8 6 4 7
Mitochondria 0 2 6 44 33 138 175 177 266 227 247 271 0 1 1 3 7 2 5 3 13 18 24 19
Nucleus 0 0 0 1 0 0 0 2 2 6 4 1 1 0 0 2 0 0 1 0 0 0 0 0
Nuclear Periphery 1 3 3 1 0 2 10 8 11 7 5 13 0 0 0 0 0 0 0 2 2 0 0 2
Nucleolus 0 0 0 0 0 0 2 5 2 1 1 1 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 1 1 1 0 3 0 1 1 0 4 2 0 1 1 0 0 0 0 0 0
Vac/Vac Membrane 15 3 14 19 70 37 57 90 80 84 31 65 2 11 6 2 8 9 5 7 5 8 13 25
Unique Cell Count 321 341 460 271 324 427 515 562 625 599 542 566 267 492 218 45 154 63 360 374 522 343 496 562
Labelled Cell Count 366 375 538 342 383 521 631 670 781 731 674 727 300 566 250 50 173 73 360 374 522 343 496 562


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.0 10.3 8.2 7.7 7.5 6.5 6.5 6.3 6.2 6.0 5.8 5.9 9.6 9.7 10.1 8.5 9.0 10.7 9.9 10.0 10.7
Std Deviation (1e-4) 1.6 1.5 1.2 1.4 1.4 1.1 1.2 1.2 1.1 1.2 1.2 1.2 1.5 1.3 1.5 1.8 1.8 2.3 2.0 1.6 2.1
Intensity Change (Log2) – – – -0.1 -0.14 -0.34 -0.35 -0.38 -0.42 -0.45 -0.5 -0.49 0.22 0.23 0.3 0.04 0.12 0.38 0.26 0.28 0.37


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.0 -2.7 -4.4 -4.3 -3.5 -4.2 -6.4 -3.8 -4.3 -0.5 -0.4 0.3 0 1.2 1.9
Bud 0 0 3.0 3.2 4.0 4.1 5.2 3.9 5.0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 2.2 1.9 -0.1 1.6 0.2 0.1 1.6 2.3 1.4 0 -0.9 0 0 5.6 0
Cytoplasm 2.1 4.5 4.7 5.2 4.4 4.5 8.3 7.2 5.8 1.5 3.2 4.3 7.0 11.7 6.0
Endoplasmic Reticulum -8.3 -13.9 -12.5 -16.7 -16.9 -18.6 -22.7 -19.1 -19.5 -0.9 -3.0 -4.6 -11.2 -16.4 -12.7
Endosome 2.7 5.6 0.8 3.0 -0.1 1.4 0.9 -1.7 -1.3 -1.1 0.7 -0.4 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 7.7 5.6 12.5 13.1 12.5 15.5 14.2 16.1 16.7 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 1.8 0 1.6 0 0 2.1 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.5 8.3 3.6 4.8 6.8 5.6 6.1 2.0 5.0 -2.0 -0.8 -0.2 0 1.2 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.0243 6.4607 6.8576 6.3362 5.7099 6.4873 8.4825 9.1147 9.4331 8.9167 8.3886 8.9012 8.1654 8.8959 9.3826 8.9552 9.0166 8.9533
Actin 0.0044 0.004 0.0106 0.0049 0.0065 0.0109 0.0138 0.0167 0.0021 0.0069 0.0033 0.0053 0.0039 0.0067 0.004 0.0034 0.0038 0.001
Bud 0.0002 0.0004 0.0003 0.0005 0.0004 0.0001 0.0001 0.0003 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0
Bud Neck 0.0005 0.0012 0.0034 0.0012 0.0015 0.001 0.0008 0.0004 0.0004 0.0011 0.0006 0.0014 0.0002 0.0003 0.0004 0.0019 0.0025 0.0008
Bud Periphery 0.0003 0.0004 0.0004 0.0007 0.0007 0.0002 0.0002 0.0003 0.0001 0.0003 0.0001 0.0001 0.0001 0.0001 0.0002 0.0002 0.0001 0.0001
Bud Site 0.0006 0.0099 0.0031 0.0008 0.0016 0.0002 0.0019 0.0018 0.0003 0.0004 0.0001 0.0001 0.0002 0.0019 0.001 0.0002 0.0003 0
Cell Periphery 0.001 0.0019 0.0009 0.0028 0.0005 0.0003 0.0009 0.0008 0.0005 0.0017 0.0003 0.0003 0.0008 0.0009 0.0013 0.0014 0.0004 0.0004
Cytoplasm 0.1932 0.3129 0.1672 0.3241 0.2175 0.2144 0.0942 0.1635 0.1076 0.2573 0.1617 0.151 0.0621 0.0756 0.1008 0.1122 0.1322 0.0965
Cytoplasmic Foci 0.0248 0.0288 0.0217 0.0184 0.0207 0.016 0.0262 0.0268 0.0184 0.0086 0.0254 0.0205 0.0173 0.0242 0.0148 0.0203 0.0308 0.0123
Eisosomes 0.0001 0.0001 0.0001 0.0002 0.0003 0.0001 0.0002 0.0001 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0 0
Endoplasmic Reticulum 0.577 0.4585 0.6177 0.4585 0.4618 0.5998 0.7026 0.6437 0.7536 0.6249 0.6661 0.6776 0.7912 0.7666 0.7746 0.7085 0.6655 0.7823
Endosome 0.0755 0.0906 0.0893 0.0891 0.1023 0.0837 0.0653 0.0732 0.07 0.0347 0.0696 0.0785 0.056 0.066 0.0521 0.0747 0.0895 0.0629
Golgi 0.0243 0.0133 0.0282 0.0396 0.0199 0.0142 0.0149 0.0263 0.0142 0.0051 0.0281 0.0174 0.0267 0.0213 0.0185 0.0155 0.0346 0.0137
Lipid Particles 0.0218 0.0206 0.0132 0.0103 0.0583 0.0043 0.025 0.023 0.0118 0.0348 0.013 0.0139 0.0151 0.0158 0.0119 0.0177 0.0191 0.0105
Mitochondria 0.0061 0.0022 0.0044 0.0129 0.0247 0.0041 0.0053 0.0021 0.0019 0.0013 0.0053 0.0035 0.0018 0.0025 0.0021 0.0018 0.0018 0.0016
None 0.0232 0.0073 0.0036 0.0013 0.0048 0.0036 0.013 0.0042 0.0012 0.0041 0.002 0.0051 0.0032 0.0028 0.0018 0.0062 0.003 0.0044
Nuclear Periphery 0.0163 0.0187 0.0135 0.0147 0.032 0.0327 0.0152 0.0078 0.0101 0.0115 0.015 0.016 0.0125 0.0076 0.0091 0.0263 0.0087 0.0077
Nucleolus 0.0001 0.0005 0.0003 0.0001 0.0038 0.0001 0.0003 0 0 0 0 0 0.0001 0.0001 0.0001 0.0001 0 0
Nucleus 0.0023 0.0076 0.0103 0.0038 0.0144 0.0045 0.0054 0.001 0.0012 0.0013 0.0027 0.0019 0.001 0.0008 0.0014 0.0018 0.0013 0.0007
Peroxisomes 0.0092 0.0005 0.0011 0.0002 0.0026 0.0011 0.0073 0.0017 0.0002 0.0002 0.0008 0.0009 0.0017 0.0005 0.0002 0.0004 0.0008 0.0002
Punctate Nuclear 0.0008 0.0034 0.0009 0.0006 0.0162 0.0013 0.0022 0.0006 0.0004 0.0002 0.0008 0.0007 0.0011 0.0005 0.0005 0.0007 0.0008 0.0003
Vacuole 0.015 0.0152 0.0078 0.013 0.0057 0.0056 0.004 0.0044 0.0047 0.0045 0.004 0.0042 0.004 0.0048 0.004 0.0048 0.0039 0.0035
Vacuole Periphery 0.0032 0.0019 0.002 0.0025 0.0036 0.0019 0.0013 0.001 0.0011 0.0009 0.001 0.0014 0.0012 0.0008 0.0011 0.0015 0.0008 0.001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 29.9635 16.0713 11.4287 19.0792 32.0504 17.9681 13.3721 16.4512 16.6977 31.9398
Translational Efficiency 0.9691 1.0214 1.06 0.7749 0.7282 1.5635 1.3084 0.6887 0.9627 0.8313

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
132 906 216 70 2044 1591 220 1934 2176 2497 436 2004

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1001.44 1105.95 1501.60 1347.40 852.14 1018.59 1143.12 1207.60 861.20 1050.29 1320.72 1212.48
Standard Deviation 150.60 167.15 243.76 198.86 128.23 137.68 165.99 185.07 134.50 154.85 274.71 187.34
Intensity Change Log 2 — 0.143210 0.584425 0.428102 — 0.257411 0.423814 0.502980 — 0.196836 0.512801 0.463009

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002449 0.002522 0.007877 0.003626 0.001410 0.002486 0.001173 0.002548 0.001473 0.002499 0.004494 0.002585
Bud Neck 0.004781 0.000615 0.006798 0.002435 0.001465 0.000778 0.001168 0.002014 0.001666 0.000719 0.003957 0.002028
Bud Site 0.019252 0.004626 0.015137 0.023559 0.003846 0.003661 0.004583 0.010305 0.004780 0.004011 0.009812 0.010768
Cell Periphery 0.003364 0.000874 0.001615 0.006813 0.001414 0.000930 0.001031 0.004179 0.001532 0.000910 0.001320 0.004271
Cytoplasm 0.091537 0.059288 0.014182 0.051090 0.126785* 0.090622 0.039590 0.055387 0.124647* 0.079253 0.027002 0.055237
Cytoplasmic Foci 0.071445 0.028488 0.045379 0.011251 0.066648 0.034963 0.010831 0.008275 0.066939 0.032614 0.027947 0.008379
Eisosomes 0.000290 0.000321 0.000104 0.000183 0.001433 0.000577 0.000079 0.000367 0.001364 0.000484 0.000092 0.000360
Endoplasmic Reticulum 0.388192* 0.811979* 0.280580* 0.656153* 0.576660* 0.730437* 0.820524* 0.845764* 0.565227* 0.760024* 0.553029* 0.839140*
Endosome 0.029924 0.015482 0.149267 0.021413 0.018693 0.014984 0.017892 0.011379 0.019375 0.015165 0.082977 0.011729
Golgi 0.025161 0.025065 0.044364 0.004112 0.074713 0.040676 0.003918 0.005638 0.071707 0.035012 0.023956 0.005585
Lipid Particles 0.035123 0.027106 0.081080 0.063318 0.079010 0.047557 0.020233 0.024381 0.076348 0.040137 0.050377 0.025742
Mitochondria 0.010805 0.003206 0.000035 0.000119 0.011631 0.005790 0.000120 0.001555 0.011581 0.004852 0.000078 0.001504
Mitotic Spindle 0.005376 0.002104 0.018036 0.003020 0.000535 0.000662 0.000479 0.001006 0.000829 0.001185 0.009177 0.001077
None 0.000165 0.003355 0.000010 0.000328 0.006839 0.002089 0.000175 0.002155 0.006434 0.002548 0.000093 0.002091
Nuclear Periphery 0.003884 0.000310 0.005288 0.001750 0.001221 0.001284 0.001993 0.000402 0.001382 0.000931 0.003626 0.000449
Nuclear Periphery Foci 0.034947 0.005294 0.108101 0.074515 0.004525 0.005799 0.054748 0.006048 0.006370 0.005616 0.081180 0.008440
Nucleolus 0.000095 0.000153 0.000035 0.000016 0.000218 0.000095 0.000021 0.000045 0.000210 0.000116 0.000028 0.000044
Nucleus 0.011422 0.001224 0.000643 0.004545 0.004007 0.002644 0.002662 0.002463 0.004457 0.002129 0.001662 0.002535
Peroxisomes 0.001342 0.001955 0.000792 0.000142 0.008578 0.003572 0.000197 0.000983 0.008139 0.002985 0.000492 0.000954
Vacuole 0.257391* 0.004547 0.213212* 0.071196 0.006664 0.007488 0.018198 0.014270 0.021874 0.006421 0.114810 0.016258
Vacuole Periphery 0.003055 0.001485 0.007465 0.000418 0.003705 0.002906 0.000383 0.000838 0.003666 0.002390 0.003892 0.000824

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.06 -2.06 -0.51 -0.51 1.42 -1.46 0.29 -2.81 -0.19 -2.21 -1.89 -2.41 -2.79 -0.27 1.46
Bud Neck 2.04 -1.08 0.92 -2.65 3.32 2.22 0.58 -1.66 -3.83 -1.90 3.15 -3.84 -1.22 -4.42 3.02
Bud Site 2.32 0.38 -0.31 -1.62 -0.57 0.18 -0.58 -4.97 -4.61 -2.86 0.83 -3.18 -4.45 -4.85 -0.29
Cell Periphery 0.97 0.66 -0.64 -1.24 -1.07 1.69 0.87 -5.12 -6.43 -5.24 2.11 0.59 -4.88 -6.67 -5.47
Cytoplasm 3.16 6.38 2.48 0.34 -2.75 7.70 11.31 16.41 7.99 -2.25 11.27 18.10 16.51 6.28 -5.65
Cytoplasmic Foci 4.75 2.67 5.88 2.89 4.48 9.36 16.46 20.63 11.75 1.11 11.32 9.90 21.51 13.04 6.25
Eisosomes -0.38 3.15 1.22 1.49 -1.00 4.52 7.49 5.71 2.65 -5.49 5.04 7.50 5.71 1.86 -5.39
Endoplasmic Reticulum -12.39 2.21 -4.33 4.26 -6.72 -14.05 -13.31 -27.19 -11.42 -1.29 -20.17 0.69 -27.77 -8.69 -14.40
Endosome 3.38 -12.26 1.44 -1.34 12.97 2.82 0.27 5.93 2.94 2.42 3.51 -11.18 6.32 3.17 12.57
Golgi -0.16 -1.75 2.13 8.02 5.75 9.72 25.74 25.37 14.94 -1.92 11.94 11.13 25.07 16.80 5.09
Lipid Particles 1.09 -4.28 -2.01 -2.63 0.88 7.91 12.78 15.18 7.02 -1.09 10.51 4.45 14.51 5.10 4.49
Mitochondria 1.15 1.70 1.69 3.00 -1.49 4.97 14.77 12.53 4.68 -7.08 6.32 14.08 11.98 4.76 -7.38
Mitotic Spindle 0.95 -1.80 0.02 -0.69 1.62 -0.46 -0.00 -1.10 -0.82 -0.99 -0.76 -2.98 -0.69 -0.09 2.82
None -3.38 1.82 -0.62 3.10 -1.22 4.40 6.66 4.04 -0.08 -3.31 3.76 6.75 3.96 0.66 -3.48
Nuclear Periphery 4.23 -1.25 1.62 -2.72 2.82 -0.17 -1.64 3.60 2.98 3.72 1.62 -4.01 4.12 2.35 5.98
Nuclear Periphery Foci 5.45 -6.16 -2.69 -4.54 1.42 -1.31 -6.66 -1.98 -0.46 6.42 0.85 -11.07 -2.29 -3.01 10.64
Nucleolus -0.48 2.05 3.43 1.13 0.83 2.34 4.13 3.64 1.66 -3.00 1.58 4.01 3.71 1.49 -1.43
Nucleus 4.95 5.16 1.28 -1.61 -1.74 3.33 1.29 2.95 -0.17 0.10 6.45 4.86 3.59 -1.91 -1.88
Peroxisomes -1.04 1.39 3.85 3.37 3.45 7.97 15.99 14.29 7.06 -6.53 8.98 15.23 14.32 6.47 -3.15
Vacuole 9.99 1.91 5.21 -4.36 4.44 -0.91 -4.55 -6.30 -5.40 1.01 7.28 -9.56 1.70 -7.52 10.17
Vacuole Periphery 1.12 -2.74 2.05 3.15 6.20 1.57 9.45 7.83 5.22 -3.23 2.98 -0.27 8.03 5.35 5.09
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in the inositol acylation of GlcN-PI; the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) forms glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
Localization
Cell Percentages ER (97%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Gwt1

Gwt1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gwt1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available